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Glycosylation-independent binding of monoclonal antibody toripalimab to FG loop of PD-1 for tumor immune checkpoint therapy.

Liu H, Guo L, Zhang J, Zhou Y, Zhou J, Yao J, Wu H, Yao S, Chen B, Chai Y, Qi J, Gao GF, Tan S, Feng H, Yan J.

MAbs. 2019 Mar 20. doi: 10.1080/19420862.2019.1596513. [Epub ahead of print]


Pseudorabies virus: a neglected zoonotic pathogen in humans?

Wong G, Lu J, Zhang W, Gao GF.

Emerg Microbes Infect. 2019;8(1):150-154. doi: 10.1080/22221751.2018.1563459. No abstract available.


Diverse biological characteristics and varied virulence of H7N9 from Wave 5.

Bao L, Bi Y, Wong G, Qi W, Li F, Lv Q, Wang L, Liu F, Yang Y, Zhang C, Liu WJ, Quan C, Jia W, Liu Y, Liu W, Liao M, Gao GF, Qin C.

Emerg Microbes Infect. 2019;8(1):94-102. doi: 10.1080/22221751.2018.1560234.


Regulation of Circadian Genes by the MAPK Pathway: Implications for Rapid Antidepressant Action.

Wang XL, Yuan K, Zhang W, Li SX, Gao GF, Lu L.

Neurosci Bull. 2019 Mar 11. doi: 10.1007/s12264-019-00358-9. [Epub ahead of print] Review.


Humoral and cellular immunity against both ZIKV and poxvirus is elicited by a two-dose regimen using DNA and non-replicating vaccinia virus-based vaccine candidates.

Zhan Y, Deng Y, Huang B, Song Q, Wang W, Yang Y, Dai L, Wang W, Yan J, Gao GF, Tan W.

Vaccine. 2019 Mar 6. pii: S0264-410X(19)30270-1. doi: 10.1016/j.vaccine.2019.02.063. [Epub ahead of print]


HIV prevalence in suspected Ebola cases during the 2014-2016 Ebola epidemic in Sierra Leone.

Liu WJ, Hu HY, Su QD, Zhang Z, Liu Y, Sun YL, Yang XD, Sun DP, Cai SJ, Yang XX, Kamara I, Kamara A, Lebby M, Kargbo B, Ongpin P, Dong XP, Shu YL, Xu WB, Wu GZ, Gboun M, Gao GF.

Infect Dis Poverty. 2019 Mar 4;8(1):15. doi: 10.1186/s40249-019-0525-9.


E-protein regulatory network links TCR signaling to effector Treg cell differentiation.

Han X, Huang H, Gao P, Zhang Q, Liu X, Jia B, Strober W, Hou B, Zhou X, Gao GF, Zhang F.

Proc Natl Acad Sci U S A. 2019 Feb 15. pii: 201800494. doi: 10.1073/pnas.1800494116. [Epub ahead of print]


Molecular basis of a protective/neutralizing monoclonal antibody targeting envelope proteins of both tick-borne encephalitis virus and louping ill virus.

Yang X, Qi J, Peng R, Dai L, Gould EA, Gao GF, Tien P.

J Virol. 2019 Feb 13. pii: JVI.02132-18. doi: 10.1128/JVI.02132-18. [Epub ahead of print]


Strengthening the role of ethnic minority women in science and medicine in China.

Hu J, Gao GF, Chen JL.

Lancet. 2019 Feb 9;393(10171):527-528. doi: 10.1016/S0140-6736(18)32108-1. No abstract available.


Comparison between human infections caused by highly and low pathogenic H7N9 avian influenza viruses in Wave Five: Clinical and virological findings.

Yang Y, Wong G, Yang L, Tan S, Li J, Bai B, Xu Z, Li H, Xu W, Zhao X, Quan C, Zheng H, Liu WJ, Liu W, Liu L, Liu Y, Bi Y, Gao GF.

J Infect. 2019 Mar;78(3):241-248. doi: 10.1016/j.jinf.2019.01.005. Epub 2019 Jan 18.


Taxonomy of the order Bunyavirales: second update 2018.

Maes P, Adkins S, Alkhovsky SV, Avšič-Županc T, Ballinger MJ, Bente DA, Beer M, Bergeron É, Blair CD, Briese T, Buchmeier MJ, Burt FJ, Calisher CH, Charrel RN, Choi IR, Clegg JCS, de la Torre JC, de Lamballerie X, DeRisi JL, Digiaro M, Drebot M, Ebihara H, Elbeaino T, Ergünay K, Fulhorst CF, Garrison AR, Gāo GF, Gonzalez JJ, Groschup MH, Günther S, Haenni AL, Hall RA, Hewson R, Hughes HR, Jain RK, Jonson MG, Junglen S, Klempa B, Klingström J, Kormelink R, Lambert AJ, Langevin SA, Lukashevich IS, Marklewitz M, Martelli GP, Mielke-Ehret N, Mirazimi A, Mühlbach HP, Naidu R, Nunes MRT, Palacios G, Papa A, Pawęska JT, Peters CJ, Plyusnin A, Radoshitzky SR, Resende RO, Romanowski V, Sall AA, Salvato MS, Sasaya T, Schmaljohn C, Shí X, Shirako Y, Simmonds P, Sironi M, Song JW, Spengler JR, Stenglein MD, Tesh RB, Turina M, Wèi T, Whitfield AE, Yeh SD, Zerbini FM, Zhang YZ, Zhou X, Kuhn JH.

Arch Virol. 2019 Mar;164(3):927-941. doi: 10.1007/s00705-018-04127-3.


Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope.

Lu X, Xiao H, Li S, Pang X, Song J, Liu S, Cheng H, Li Y, Wang X, Huang C, Guo T, Ter Meulen J, Daffis S, Yan J, Dai L, Rao Z, Klenk HD, Qi J, Shi Y, Gao GF.

Cell Rep. 2019 Jan 8;26(2):438-446.e5. doi: 10.1016/j.celrep.2018.12.065.


Low Pathogenic Avian Influenza A (H5N7) Virus Isolated from a Domestic Duck in Dongting Lake Wetland of China, 2016.

Ma L, Liu H, Wang R, Jin T, Liu D, Gao GF, Chen Q.

Virol Sin. 2019 Feb;34(1):97-101. doi: 10.1007/s12250-018-0081-7. Epub 2019 Jan 4. No abstract available.


Binding mode of the side-by-side two-IgV molecule CD226/DNAM-1 to its ligand CD155/Necl-5.

Wang H, Qi J, Zhang S, Li Y, Tan S, Gao GF.

Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):988-996. doi: 10.1073/pnas.1815716116. Epub 2018 Dec 27.


ID2 and ID3 are indispensable for Th1 cell differentiation during influenza virus infection in mice.

Han X, Liu H, Huang H, Liu X, Jia B, Gao GF, Zhang F.

Eur J Immunol. 2019 Mar;49(3):476-489. doi: 10.1002/eji.201847822. Epub 2019 Jan 4.


Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells.

Gannon HS, Zou T, Kiessling MK, Gao GF, Cai D, Choi PS, Ivan AP, Buchumenski I, Berger AC, Goldstein JT, Cherniack AD, Vazquez F, Tsherniak A, Levanon EY, Hahn WC, Meyerson M.

Nat Commun. 2018 Dec 21;9(1):5450. doi: 10.1038/s41467-018-07824-4.


On the Centenary of the Spanish Flu: Being Prepared for the Next Pandemic.

Liu WJ, Bi Y, Wang D, Gao GF.

Virol Sin. 2018 Dec;33(6):463-466. doi: 10.1007/s12250-018-0079-1. Epub 2018 Dec 20. No abstract available.


Clinical, immunological and bacteriological characteristics of H7N9 patients nosocomially co-infected by Acinetobacter Baumannii: a case control study.

Liu WJ, Zou R, Hu Y, Zhao M, Quan C, Tan S, Luo K, Yuan J, Zheng H, Liu J, Liu M, Bi Y, Yan J, Zhu B, Wang D, Wu G, Liu L, Yuen KY, Gao GF, Liu Y.

BMC Infect Dis. 2018 Dec 14;18(1):664. doi: 10.1186/s12879-018-3447-4.


Equine-origin immunoglobulin fragments protects nonhuman primates from Ebola virus disease.

Wang H, Wong G, Zhu W, He S, Zhao Y, Yan F, Rahim MN, Bi Y, Zhang Z, Cheng K, Jin H, Cao Z, Zheng X, Gai W, Bai J, Chen W, Zou Y, Gao Y, Gao GF, Yang S, Xia X, Qiu X.

J Virol. 2018 Dec 12. pii: JVI.01548-18. doi: 10.1128/JVI.01548-18. [Epub ahead of print]


Introduction to Special Issue on Pathogens in China.

Liang G, Gao GF, Higgs S.

Vector Borne Zoonotic Dis. 2019 Jan;19(1):1-2. doi: 10.1089/vbz.2018.2413. Epub 2018 Dec 12. No abstract available.


Isolation and Identification of a Highly Divergent Kaeng Khoi Virus from Bat Flies (Eucampsipoda sundaica) in China.

Xu Z, Yang W, Feng Y, Li Y, Fu S, Li X, Song J, Zhang H, Zhang Y, Liu WJ, Gao GF, Liang G.

Vector Borne Zoonotic Dis. 2019 Jan;19(1):73-80. doi: 10.1089/vbz.2018.2350. Epub 2018 Dec 11.


Emergence and adaptation of H3N2 canine influenza virus from avian influenza virus: An overlooked role of dogs in interspecies transmission.

He W, Li G, Zhu H, Shi W, Wang R, Zhang C, Bi Y, Lai A, Gao GF, Su S.

Transbound Emerg Dis. 2019 Mar;66(2):842-851. doi: 10.1111/tbed.13093. Epub 2019 Jan 5.


Structure-function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans.

Huang KA, Rijal P, Jiang H, Wang B, Schimanski L, Dong T, Liu YM, Chang P, Iqbal M, Wang MC, Chen Z, Song R, Huang CC, Yang JH, Qi J, Lin TY, Li A, Powell TJ, Jan JT, Ma C, Gao GF, Shi Y, Townsend AR.

Nat Microbiol. 2019 Feb;4(2):306-315. doi: 10.1038/s41564-018-0303-7. Epub 2018 Nov 26.


Transcripts of antibacterial peptides in chicken erythrocytes infected with Marek's disease virus.

Niu S, Jahejo AR, Jia FJ, Li X, Ning GB, Zhang D, Ma HL, Hao WF, Gao WW, Zhao YJ, Gao SM, Li GL, Li JH, Yan F, Gao RK, Bi YH, Han LX, Gao GF, Tian WX.

BMC Vet Res. 2018 Nov 21;14(1):363. doi: 10.1186/s12917-018-1678-7.


Spartina alterniflora invasion alters soil bacterial communities and enhances soil N2O emissions by stimulating soil denitrification in mangrove wetland.

Gao GF, Li PF, Zhong JX, Shen ZJ, Chen J, Li YT, Isabwe A, Zhu XY, Ding QS, Zhang S, Gao CH, Zheng HL.

Sci Total Environ. 2019 Feb 25;653:231-240. doi: 10.1016/j.scitotenv.2018.10.277. Epub 2018 Oct 21.


Evaluation of Zika Virus-specific T-cell Responses in Immunoprivileged Organs of Infected Ifnar1-/- Mice.

Zhang Y, Zhang H, Ma W, Liu K, Zhao M, Zhao Y, Lu X, Zhang F, Li X, Gao GF, Liu WJ.

J Vis Exp. 2018 Oct 17;(140). doi: 10.3791/58110.


Limited Cross-Linking of 4-1BB by 4-1BB Ligand and the Agonist Monoclonal Antibody Utomilumab.

Li Y, Tan S, Zhang C, Chai Y, He M, Zhang CW, Wang Q, Tong Z, Liu K, Lei Y, Liu WJ, Liu Y, Tian Z, Cao X, Yan J, Qi J, Tien P, Gao S, Gao GF.

Cell Rep. 2018 Oct 23;25(4):909-920.e4. doi: 10.1016/j.celrep.2018.09.073.


An Invariant Arginine in Common with MHC Class II Allows Extension at the C-Terminal End of Peptides Bound to Chicken MHC Class I.

Xiao J, Xiang W, Zhang Y, Peng W, Zhao M, Niu L, Chai Y, Qi J, Wang F, Qi P, Pan C, Han L, Wang M, Kaufman J, Gao GF, Liu WJ.

J Immunol. 2018 Nov 15;201(10):3084-3095. doi: 10.4049/jimmunol.1800611. Epub 2018 Oct 19.


Naturally Occurring Single Mutations in Ebola Virus Observably Impact Infectivity.

Wong G, He S, Leung A, Cao W, Bi Y, Zhang Z, Zhu W, Wang L, Zhao Y, Cheng K, Liu D, Liu W, Kobasa D, Gao GF, Qiu X.

J Virol. 2018 Dec 10;93(1). pii: e01098-18. doi: 10.1128/JVI.01098-18. Print 2019 Jan 1.


Continued reassortment of avian H6 influenza viruses from Southern China, 2014-2016.

Li J, Quan C, Xie Y, Ke C, Nie Y, Chen Q, Hu T, Chen J, Wong G, Wang Q, Feng L, Yu H, Liu Y, Liu W, Gao GF, Liu WJ, Shi W, Bi Y.

Transbound Emerg Dis. 2019 Jan;66(1):592-598. doi: 10.1111/tbed.13037. Epub 2018 Oct 26.


Origin, Genetic Diversity, and Evolutionary Dynamics of Novel Porcine Circovirus 3.

Li G, He W, Zhu H, Bi Y, Wang R, Xing G, Zhang C, Zhou J, Yuen KY, Gao GF, Su S.

Adv Sci (Weinh). 2018 Jul 4;5(9):1800275. doi: 10.1002/advs.201800275. eCollection 2018 Sep.


Structural and functional insights into MCR-2 mediated colistin resistance.

Wang X, Lu Q, Qi J, Chai Y, Wang Y, Gao GF.

Sci China Life Sci. 2018 Nov;61(11):1432-1436. doi: 10.1007/s11427-018-9363-4. Epub 2018 Sep 3. No abstract available.


Phylogenomic analysis unravels evolution of yellow fever virus within hosts.

Chen C, Jiang D, Ni M, Li J, Chen Z, Liu J, Ye H, Wong G, Li W, Zhang Y, Wang B, Bi Y, Chen D, Zhang P, Zhao X, Kong Y, Shi W, Du P, Xiao G, Ma J, Gao GF, Cui J, Zhang F, Liu W, Bo X, Li A, Zeng H, Liu D.

PLoS Negl Trop Dis. 2018 Sep 6;12(9):e0006738. doi: 10.1371/journal.pntd.0006738. eCollection 2018 Sep.


[Antibiotic resistome in farm animals and their related environments: a review].

Wang Y, Hu Y, Zhu B, Jiao X, Gao GF.

Sheng Wu Gong Cheng Xue Bao. 2018 Aug 25;34(8):1226-1233. doi: 10.13345/j.cjb.180163. Chinese.


Clinical and immunological characteristics of human infections with H5N6 avian influenza virus.

Bi Y, Tan S, Yang Y, Wong G, Zhao M, Zhang Q, Wang Q, Zhao X, Li L, Yuan J, Li H, Li H, Xu W, Shi W, Quan C, Zou R, Li J, Zheng H, Yang L, Liu WJ, Liu D, Wang H, Qin Y, Liu L, Jiang C, Liu W, Lu L, Gao GF, Liu Y.

Clin Infect Dis. 2018 Aug 16. doi: 10.1093/cid/ciy681. [Epub ahead of print]


Development of a quadruple qRT-PCR assay for simultaneous identification of highly and low pathogenic H7N9 avian influenza viruses and characterization against oseltamivir resistance.

Yang Y, Li S, Wong G, Ma S, Xu Z, Zhao X, Li H, Xu W, Zheng H, Lin J, Zhao Q, Liu W, Liu Y, Gao GF, Bi Y.

BMC Infect Dis. 2018 Aug 15;18(1):406. doi: 10.1186/s12879-018-3302-7.


Heterosubtypic Protections against Human-Infecting Avian Influenza Viruses Correlate to Biased Cross-T-Cell Responses.

Zhao M, Liu K, Luo J, Tan S, Quan C, Zhang S, Chai Y, Qi J, Li Y, Bi Y, Xiao H, Wong G, Zhou J, Jiang T, Liu W, Yu H, Yan J, Liu Y, Shu Y, Wu G, Wu A, Gao GF, Liu WJ.

MBio. 2018 Aug 7;9(4). pii: e01408-18. doi: 10.1128/mBio.01408-18.


Serological Investigation of Laboratory-Confirmed and Suspected Ebola Virus Disease Patients During the Late Phase of the Ebola Outbreak in Sierra Leone.

Liu Y, Sun Y, Wu W, Li A, Yang X, Zhang S, Li C, Su Q, Cai S, Sun D, Hu H, Zhang Z, Yang X, Kamara I, Koroma S, Bangura G, Tia A, Kamara A, Lebby M, Kargbo B, Li J, Wang S, Dong X, Shu Y, Xu W, Gao GF, Wu G, Li D, Liu WJ, Liang M.

Virol Sin. 2018 Aug;33(4):323-334. doi: 10.1007/s12250-018-0044-z. Epub 2018 Jul 31.


A case of Naegleria fowleri related primary amoebic meningoencephalitis in China diagnosed by next-generation sequencing.

Wang Q, Li J, Ji J, Yang L, Chen L, Zhou R, Yang Y, Zheng H, Yuan J, Li L, Bi Y, Gao GF, Ma J, Liu Y.

BMC Infect Dis. 2018 Jul 28;18(1):349. doi: 10.1186/s12879-018-3261-z.


Genomic characterizations of H4 subtype avian influenza viruses from live poultry markets in Sichuan province of China, 2014-2015.

Quan C, Huang T, Chen X, Zhang J, Wang Q, Zhang C, Zhang T, Zhou L, Shu L, Long C, Yang L, Du X, Zhao Y, Liu P, Song H, Shi W, Bi Y, Lv Q, Liu WJ, Gao GF.

Sci China Life Sci. 2018 Sep;61(9):1123-1126. doi: 10.1007/s11427-018-9327-4. Epub 2018 Jul 9. No abstract available.


Standardized assays for determining the catalytic activity and kinetics of peroxidase-like nanozymes.

Jiang B, Duan D, Gao L, Zhou M, Fan K, Tang Y, Xi J, Bi Y, Tong Z, Gao GF, Xie N, Tang A, Nie G, Liang M, Yan X.

Nat Protoc. 2018 Jul;13(7):1506-1520. doi: 10.1038/s41596-018-0001-1.


CD8+ T-Cell Response-Associated Evolution of Hepatitis B Virus Core Protein and Disease Progress.

Zhang Y, Wu Y, Deng M, Xu D, Li X, Xu Z, Hu J, Zhang H, Liu K, Zhao Y, Gao F, Bi S, Gao GF, Zhao J, Liu WJ, Meng S.

J Virol. 2018 Aug 16;92(17). pii: e02120-17. doi: 10.1128/JVI.02120-17. Print 2018 Sep 1.


Prolonged Evolution of Virus-Specific Memory T Cell Immunity after Severe Avian Influenza A (H7N9) Virus Infection.

Zhao M, Chen J, Tan S, Dong T, Jiang H, Zheng J, Quan C, Liao Q, Zhang H, Wang X, Wang Q, Bi Y, Liu F, Feng L, Horby PW, Klenerman P, Gao GF, Liu WJ, Yu H.

J Virol. 2018 Aug 16;92(17). pii: e01024-18. doi: 10.1128/JVI.01024-18. Print 2018 Sep 1.


Proteomic Analysis of Zika Virus Infected Primary Human Fetal Neural Progenitors Suggests a Role for Doublecortin in the Pathological Consequences of Infection in the Cortex.

Jiang X, Dong X, Li SH, Zhou YP, Rayner S, Xia HM, Gao GF, Yuan H, Tang YP, Luo MH.

Front Microbiol. 2018 Jun 5;9:1067. doi: 10.3389/fmicb.2018.01067. eCollection 2018.


Proteomic analysis on mangrove plant Avicennia marina leaves reveals nitric oxide enhances the salt tolerance by up-regulating photosynthetic and energy metabolic protein expression.

Shen ZJ, Chen J, Ghoto K, Hu WJ, Gao GF, Luo MR, Li Z, Simon M, Zhu XY, Zheng HL.

Tree Physiol. 2018 Nov 1;38(11):1605-1622. doi: 10.1093/treephys/tpy058.


Exotic Spartina alterniflora invasion increases CH4 while reduces CO2 emissions from mangrove wetland soils in southeastern China.

Gao GF, Li PF, Shen ZJ, Qin YY, Zhang XM, Ghoto K, Zhu XY, Zheng HL.

Sci Rep. 2018 Jun 18;8(1):9243. doi: 10.1038/s41598-018-27625-5.


Zika Virus Envelope Protein and Antibody Complexes.

Dai L, Wang Q, Song H, Gao GF.

Subcell Biochem. 2018;88:147-168. doi: 10.1007/978-981-10-8456-0_7. Review.


Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells.

Chu H, Chan CM, Zhang X, Wang Y, Yuan S, Zhou J, Au-Yeung RK, Sze KH, Yang D, Shuai H, Hou Y, Li C, Zhao X, Poon VK, Leung SP, Yeung ML, Yan J, Lu G, Jin DY, Gao GF, Chan JF, Yuen KY.

J Biol Chem. 2018 Jul 27;293(30):11709-11726. doi: 10.1074/jbc.RA118.001897. Epub 2018 Jun 10.


Structures of Zika Virus E & NS1: Relations with Virus Infection and Host Immune Responses.

Shi Y, Dai L, Song H, Gao GF.

Adv Exp Med Biol. 2018;1062:77-87. doi: 10.1007/978-981-10-8727-1_6. Review.


Cellular-Beacon-Mediated Counting for the Ultrasensitive Detection of Ebola Virus on an Integrated Micromagnetic Platform.

Hong SL, Zhang YN, Liu YH, Tang M, Pang DW, Wong G, Chen J, Qiu X, Gao GF, Liu W, Bi Y, Zhang ZL.

Anal Chem. 2018 Jun 19;90(12):7310-7317. doi: 10.1021/acs.analchem.8b00513. Epub 2018 Jun 7.


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