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Items: 1 to 50 of 370

1.

The Aftermath of Surviving Acute Radiation Hematopoietic Syndrome and its Mitigation.

Micewicz ED, Iwamoto KS, Ratikan JA, Nguyen C, Xie MW, Cheng G, Boxx GM, Deriu E, Damoiseaux RD, Whitelegge JP, Ruchala PP, Avetisyan R, Jung ME, Lawson G, Nemeth E, Ganz T, Sayre JW, McBride WH, Schaue D.

Radiat Res. 2019 Feb 7. doi: 10.1667/RR15231.1. [Epub ahead of print]

PMID:
30730284
2.

Increased gene copy number of DEFA1/DEFA3 worsens sepsis by inducing endothelial pyroptosis.

Chen Q, Yang Y, Hou J, Shu Q, Yin Y, Fu W, Han F, Hou T, Zeng C, Nemeth E, Linzmeier R, Ganz T, Fang X.

Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3161-3170. doi: 10.1073/pnas.1812947116. Epub 2019 Feb 4.

3.

Erythrocytes and erythroblasts give up iron.

Ganz T.

Blood. 2018 Nov 8;132(19):2004-2005. doi: 10.1182/blood-2018-09-876102. No abstract available.

PMID:
30409893
4.

Anemia of inflammation.

Weiss G, Ganz T, Goodnough LT.

Blood. 2019 Jan 3;133(1):40-50. doi: 10.1182/blood-2018-06-856500. Epub 2018 Nov 6. Review.

PMID:
30401705
5.

Iron homeostasis in pregnancy and spontaneous abortion.

Guo Y, Zhang N, Zhang D, Ren Q, Ganz T, Liu S, Nemeth E.

Am J Hematol. 2019 Feb;94(2):184-188. doi: 10.1002/ajh.25341. Epub 2018 Nov 26.

PMID:
30394565
6.

Erythropoietin and iron-a conflicted alliance?

Ganz T.

Kidney Int. 2018 Nov;94(5):851-853. doi: 10.1016/j.kint.2018.07.027.

PMID:
30348300
7.

Mechanisms responsible for reduced erythropoiesis during androgen deprivation therapy in men with prostate cancer.

Gagliano-Jucá T, Pencina KM, Ganz T, Travison TG, Kantoff PW, Nguyen PL, Taplin ME, Kibel AS, Li Z, Huang G, Edwards RR, Nemeth E, Basaria S.

Am J Physiol Endocrinol Metab. 2018 Dec 1;315(6):E1185-E1193. doi: 10.1152/ajpendo.00272.2018. Epub 2018 Oct 16.

PMID:
30325657
8.

Erythroferrone is not required for the glucoregulatory and hematologic effects of chronic erythropoietin treatment in mice.

Coffey R, Sardo U, Kautz L, Gabayan V, Nemeth E, Ganz T.

Physiol Rep. 2018 Sep;6(19):e13890. doi: 10.14814/phy2.13890.

9.

Calcium is an essential cofactor for metal efflux by the ferroportin transporter family.

Deshpande CN, Ruwe TA, Shawki A, Xin V, Vieth KR, Valore EV, Qiao B, Ganz T, Nemeth E, Mackenzie B, Jormakka M.

Nat Commun. 2018 Aug 6;9(1):3075. doi: 10.1038/s41467-018-05446-4.

10.

Dysregulated iron metabolism in polycythemia vera: etiology and consequences.

Ginzburg YZ, Feola M, Zimran E, Varkonyi J, Ganz T, Hoffman R.

Leukemia. 2018 Oct;32(10):2105-2116. doi: 10.1038/s41375-018-0207-9. Epub 2018 Jul 24. Review.

11.

Effects of erythropoietin on fibroblast growth factor 23 in mice and humans.

Hanudel MR, Eisenga MF, Rappaport M, Chua K, Qiao B, Jung G, Gabayan V, Gales B, Ramos G, de Jong MA, van Zanden JJ, de Borst MH, Bakker SJL, Nemeth E, Salusky IB, Gaillard CAJM, Ganz T.

Nephrol Dial Transplant. 2018 Jul 10. doi: 10.1093/ndt/gfy189. [Epub ahead of print]

PMID:
30007314
12.

Erythropoietic regulators of iron metabolism.

Ganz T.

Free Radic Biol Med. 2019 Mar;133:69-74. doi: 10.1016/j.freeradbiomed.2018.07.003. Epub 2018 Jul 5. Review.

PMID:
29981834
13.

Hepcidin Protects against Lethal Escherichia coli Sepsis in Mice Inoculated with Isolates from Septic Patients.

Stefanova D, Raychev A, Deville J, Humphries R, Campeau S, Ruchala P, Nemeth E, Ganz T, Bulut Y.

Infect Immun. 2018 Jun 21;86(7). pii: e00253-18. doi: 10.1128/IAI.00253-18. Print 2018 Jul.

14.

Evaluation of serum markers for improved detection of autologous blood transfusions.

Cox HD, Miller GD, Lai A, Cushman D, Ganz T, Eichner D.

Haematologica. 2018 Oct;103(10):e443-e445. doi: 10.3324/haematol.2018.190918. Epub 2018 Apr 19. No abstract available.

15.

Fetal presentation of congenital dyserythropoietic anemia type 1 with novel compound heterozygous CDAN1 mutations.

Meznarich JA, Draper L, Christensen RD, Yaish HM, Luem ND, Pysher TJ, Jung G, Nemeth E, Ganz T, Ward DM.

Blood Cells Mol Dis. 2018 Jul;71:63-66. doi: 10.1016/j.bcmd.2018.03.002. Epub 2018 Mar 20.

PMID:
29599085
16.

Iron storage disease (hemochromatosis) and hepcidin response to iron load in two species of pteropodid fruit bats relative to the common vampire bat.

Stasiak IM, Smith DA, Ganz T, Crawshaw GJ, Hammermueller JD, Bienzle D, Lillie BN.

J Comp Physiol B. 2018 Jul;188(4):683-694. doi: 10.1007/s00360-018-1155-4. Epub 2018 Mar 29.

PMID:
29594459
17.

Therapeutic recommendations in HFE hemochromatosis for p.Cys282Tyr (C282Y/C282Y) homozygous genotype.

Adams P, Altes A, Brissot P, Butzeck B, Cabantchik I, Cançado R, Distante S, Evans P, Evans R, Ganz T, Girelli D, Hultcrantz R, McLaren G, Marris B, Milman N, Nemeth E, Nielsen P, Pineau B, Piperno A, Porto G, Prince D, Ryan J, Sanchez M, Santos P, Swinkels D, Teixeira E, Toska K, Vanclooster A, White D; Contributors and Hemochromatosis International Taskforce.

Hepatol Int. 2018 Mar;12(2):83-86. doi: 10.1007/s12072-018-9855-0. Epub 2018 Mar 27.

18.

Positive Iron Balance in Chronic Kidney Disease: How Much is Too Much and How to Tell?

Wish JB, Aronoff GR, Bacon BR, Brugnara C, Eckardt KU, Ganz T, Macdougall IC, Núñez J, Perahia AJ, Wood JC.

Am J Nephrol. 2018;47(2):72-83. doi: 10.1159/000486968. Epub 2018 Feb 13.

19.

Levels of the erythropoietin-responsive hormone erythroferrone in mice and humans with chronic kidney disease.

Hanudel MR, Rappaport M, Chua K, Gabayan V, Qiao B, Jung G, Salusky IB, Ganz T, Nemeth E.

Haematologica. 2018 Apr;103(4):e141-e142. doi: 10.3324/haematol.2017.181743. Epub 2018 Feb 1. No abstract available.

20.

Comment on "Serum Hepcidin and Soluble Transferrin Receptor in the Assessment of Iron Metabolism in Children on a Vegetarian Diet".

Rzymski P, Ganz T.

Biol Trace Elem Res. 2018 Sep;185(1):252-254. doi: 10.1007/s12011-018-1241-1. Epub 2018 Jan 10. No abstract available.

21.

Structure-function analysis of ferroportin defines the binding site and an alternative mechanism of action of hepcidin.

Aschemeyer S, Qiao B, Stefanova D, Valore EV, Sek AC, Ruwe TA, Vieth KR, Jung G, Casu C, Rivella S, Jormakka M, Mackenzie B, Ganz T, Nemeth E.

Blood. 2018 Feb 22;131(8):899-910. doi: 10.1182/blood-2017-05-786590. Epub 2017 Dec 13.

PMID:
29237594
22.

Correction to: Iron and infection.

Ganz T.

Int J Hematol. 2018 Jan;107(1):122. doi: 10.1007/s12185-017-2385-z.

PMID:
29197980
23.

Iron and infection.

Ganz T.

Int J Hematol. 2018 Jan;107(1):7-15. doi: 10.1007/s12185-017-2366-2. Epub 2017 Nov 16. Review. Erratum in: Int J Hematol. 2017 Dec 2;:.

PMID:
29147843
24.

Effects of a stand-alone web-based electronic screening and brief intervention targeting alcohol use in university students of legal drinking age: A randomized controlled trial.

Ganz T, Braun M, Laging M, Schermelleh-Engel K, Michalak J, Heidenreich T.

Addict Behav. 2018 Feb;77:81-88. doi: 10.1016/j.addbeh.2017.09.017. Epub 2017 Sep 28.

PMID:
28985586
25.

Influences of Breakfast on Clock Gene Expression and Postprandial Glycemia in Healthy Individuals and Individuals With Diabetes: A Randomized Clinical Trial.

Jakubowicz D, Wainstein J, Landau Z, Raz I, Ahren B, Chapnik N, Ganz T, Menaged M, Barnea M, Bar-Dayan Y, Froy O.

Diabetes Care. 2017 Nov;40(11):1573-1579. doi: 10.2337/dc16-2753. Epub 2017 Aug 22.

PMID:
28830875
26.

Erythropoietin stimulates murine and human fibroblast growth factor-23, revealing novel roles for bone and bone marrow.

Clinkenbeard EL, Hanudel MR, Stayrook KR, Appaiah HN, Farrow EG, Cass TA, Summers LJ, Ip CS, Hum JM, Thomas JC, Ivan M, Richine BM, Chan RJ, Clemens TL, Schipani E, Sabbagh Y, Xu L, Srour EF, Alvarez MB, Kacena MA, Salusky IB, Ganz T, Nemeth E, White KE.

Haematologica. 2017 Nov;102(11):e427-e430. doi: 10.3324/haematol.2017.167882. Epub 2017 Aug 17. No abstract available.

27.

Hamp1 mRNA and plasma hepcidin levels are influenced by sex and strain but do not predict tissue iron levels in inbred mice.

McLachlan S, Page KE, Lee SM, Loguinov A, Valore E, Hui ST, Jung G, Zhou J, Lusis AJ, Fuqua B, Ganz T, Nemeth E, Vulpe CD.

Am J Physiol Gastrointest Liver Physiol. 2017 Nov 1;313(5):G511-G523. doi: 10.1152/ajpgi.00307.2016. Epub 2017 Aug 10.

28.

CXCL13 levels are elevated in patients with Waldenström macroglobulinemia, and are predictive of major response to ibrutinib.

Vos JM, Tsakmaklis N, Patterson CJ, Meid K, Castillo JJ, Brodsky P, Ganz T, Pals ST, Kersten MJ, Xu L, Yang G, Treon SP, Hunter ZR.

Haematologica. 2017 Nov;102(11):e452-e455. doi: 10.3324/haematol.2017.172627. Epub 2017 Aug 10. No abstract available.

29.

Peroxiredoxin-2: A Novel Regulator of Iron Homeostasis in Ineffective Erythropoiesis.

Matte A, De Falco L, Federti E, Cozzi A, Iolascon A, Levi S, Mohandas N, Zamo A, Bruno M, Lebouef C, Janin A, Siciliano A, Ganz T, Federico G, Carlomagno F, Mueller S, Silva I, Carbone C, Melisi D, Kim DW, Choi SY, De Franceschi L.

Antioxid Redox Signal. 2018 Jan 1;28(1):1-14. doi: 10.1089/ars.2017.7051. Epub 2017 Sep 6.

PMID:
28793778
30.

NIH Centers for Accelerated Innovations Program: principles, practices, successes and challenges.

Antman EM, Di Corleto PE, Freeman MW, Ganz T, Golan DE, Kitterman R, Loscalzo J, Low M, McKenna E, O'Connor AC, Palazzolo M, Parrish J, Reizes O, Ross RS, Vaughan C, Vince DG, Watts L; NIH Centers for Accelerated Innovations.

Nat Rev Drug Discov. 2017 Oct;16(10):663-664. doi: 10.1038/nrd.2017.131. Epub 2017 Aug 4. No abstract available.

31.

Immunoassay for human serum erythroferrone.

Ganz T, Jung G, Naeim A, Ginzburg Y, Pakbaz Z, Walter PB, Kautz L, Nemeth E.

Blood. 2017 Sep 7;130(10):1243-1246. doi: 10.1182/blood-2017-04-777987. Epub 2017 Jul 24.

32.

Iron-related markers are associated with infection after liver transplantation.

Chow JKL, Ganz T, Ruthazer R, Simpson MA, Pomfret EA, Gordon FD, Westerman ME, Snydman DR.

Liver Transpl. 2017 Dec;23(12):1541-1552. doi: 10.1002/lt.24817.

33.

Iron homeostasis: An anthropocentric perspective.

Coffey R, Ganz T.

J Biol Chem. 2017 Aug 4;292(31):12727-12734. doi: 10.1074/jbc.R117.781823. Epub 2017 Jun 14. Review.

34.

Does Pathological Iron Overload Impair the Function of Human Lungs?

Ganz T.

EBioMedicine. 2017 Jun;20:13-14. doi: 10.1016/j.ebiom.2017.05.023. Epub 2017 May 17. No abstract available.

35.

Endogenous hepcidin and its agonist mediate resistance to selected infections by clearing non-transferrin-bound iron.

Stefanova D, Raychev A, Arezes J, Ruchala P, Gabayan V, Skurnik M, Dillon BJ, Horwitz MA, Ganz T, Bulut Y, Nemeth E.

Blood. 2017 Jul 20;130(3):245-257. doi: 10.1182/blood-2017-03-772715. Epub 2017 May 2.

36.

In a Mouse Model of Sepsis, Hepcidin Ablation Ameliorates Anemia More Effectively than Iron and Erythropoietin Treatment.

Khorramian E, Fung E, Chua K, Gabayan V, Ganz T, Nemeth E, Kim A.

Shock. 2017 Oct;48(4):490-497. doi: 10.1097/SHK.0000000000000886.

37.

Hepcidin-mediated iron sequestration protects against bacterial dissemination during pneumonia.

Michels KR, Zhang Z, Bettina AM, Cagnina RE, Stefanova D, Burdick MD, Vaulont S, Nemeth E, Ganz T, Mehrad B.

JCI Insight. 2017 Mar 23;2(6):e92002. doi: 10.1172/jci.insight.92002.

38.

Mice lacking liver-specific β-catenin develop steatohepatitis and fibrosis after iron overload.

Preziosi ME, Singh S, Valore EV, Jung G, Popovic B, Poddar M, Nagarajan S, Ganz T, Monga SP.

J Hepatol. 2017 Aug;67(2):360-369. doi: 10.1016/j.jhep.2017.03.012. Epub 2017 Mar 22.

39.

Erythroferrone and matriptase-2 independently regulate hepcidin expression.

Aschemeyer S, Gabayan V, Ganz T, Nemeth E, Kautz L.

Am J Hematol. 2017 May;92(5):E61-E63. doi: 10.1002/ajh.24672. Epub 2017 Feb 24. No abstract available.

40.

Increased serum hepcidin contributes to the anemia of chronic kidney disease in a murine model.

Hanudel MR, Rappaport M, Gabayan V, Jung G, Salusky IB, Nemeth E, Ganz T, Zaritsky J.

Haematologica. 2017 Mar;102(3):e85-e88. doi: 10.3324/haematol.2016.150433. Epub 2016 Nov 24. No abstract available.

41.

Macrophages and Iron Metabolism.

Ganz T.

Microbiol Spectr. 2016 Oct;4(5). doi: 10.1128/microbiolspec.MCHD-0037-2016. Review.

PMID:
27763254
42.

Effects of dietary iron intake and chronic kidney disease on fibroblast growth factor 23 metabolism in wild-type and hepcidin knockout mice.

Hanudel MR, Chua K, Rappaport M, Gabayan V, Valore E, Goltzman D, Ganz T, Nemeth E, Salusky IB.

Am J Physiol Renal Physiol. 2016 Dec 1;311(6):F1369-F1377. doi: 10.1152/ajprenal.00281.2016. Epub 2016 Oct 12.

43.

Hepcidin.

Ganz T.

Rinsho Ketsueki. 2016;57(10):1913-1917.

PMID:
27725588
44.

Erythroferrone contributes to hepcidin repression in a mouse model of malarial anemia.

Latour C, Wlodarczyk MF, Jung G, Gineste A, Blanchard N, Ganz T, Roth MP, Coppin H, Kautz L.

Haematologica. 2017 Jan;102(1):60-68. doi: 10.3324/haematol.2016.150227. Epub 2016 Sep 22.

45.

Serum asymmetric dimethylarginine and arginine levels predict microvascular and macrovascular complications in type 2 diabetes mellitus.

Ganz T, Wainstein J, Gilad S, Limor R, Boaz M, Stern N.

Diabetes Metab Res Rev. 2017 Feb;33(2). doi: 10.1002/dmrr.2836. Epub 2016 Oct 5.

PMID:
27393712
46.

Iron Balance and the Role of Hepcidin in Chronic Kidney Disease.

Ganz T, Nemeth E.

Semin Nephrol. 2016 Mar;36(2):87-93. doi: 10.1016/j.semnephrol.2016.02.001. Review.

47.

Minihepcidin peptides as disease modifiers in mice affected by β-thalassemia and polycythemia vera.

Casu C, Oikonomidou PR, Chen H, Nandi V, Ginzburg Y, Prasad P, Fleming RE, Shah YM, Valore EV, Nemeth E, Ganz T, MacDonald B, Rivella S.

Blood. 2016 Jul 14;128(2):265-76. doi: 10.1182/blood-2015-10-676742. Epub 2016 May 6.

48.

Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics.

Kalinowski DS, Stefani C, Toyokuni S, Ganz T, Anderson GJ, Subramaniam NV, Trinder D, Olynyk JK, Chua A, Jansson PJ, Sahni S, Lane DJ, Merlot AM, Kovacevic Z, Huang ML, Lee CS, Richardson DR.

Biochim Biophys Acta. 2016 Apr;1863(4):727-48. doi: 10.1016/j.bbamcr.2016.01.026. Epub 2016 Feb 2. Review.

49.

Isocitrate treatment of acute anemia of inflammation in a mouse model.

Kim A, Fung E, Parikh SG, Gabayan V, Nemeth E, Ganz T.

Blood Cells Mol Dis. 2016 Jan;56(1):31-6. doi: 10.1016/j.bcmd.2015.09.007. Epub 2015 Sep 28.

50.

Dynamic polarization flip in nanoripples on photoexcited Ti surface near its surface plasmon resonance.

Kudryashov SI, Makarov SV, Ionin AA, Nathala CS, Ajami A, Ganz T, Assion A, Husinsky W.

Opt Lett. 2015 Nov 1;40(21):4967-70. doi: 10.1364/OL.40.004967.

PMID:
26512495

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