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Items: 1 to 50 of 124

1.

A comparison of medical education in Germany and the United States: from applying to medical school to the beginnings of residency.

Zavlin D, Jubbal KT, Noé JG, Gansbacher B.

Ger Med Sci. 2017 Sep 25;15:Doc15. doi: 10.3205/000256. eCollection 2017. Review.

2.

Clinical Development and Commercialization of Advanced Therapy Medicinal Products in the European Union: How Are the Product Pipeline and Regulatory Framework Evolving?

Boráň T, Menezes-Ferreira M, Reischl I, Celis P, Ferry N, Gänsbacher B, Krafft H, Lipucci di Paola M, Sladowski D, Salmikangas P.

Hum Gene Ther Clin Dev. 2017 Sep;28(3):126-135. doi: 10.1089/humc.2016.193. Epub 2017 May 16. Review.

PMID:
28510497
3.

Optimizing adenoviral transduction of endothelial cells under flow conditions.

Anton M, Wolf A, Mykhaylyk O, Koch C, Gansbacher B, Plank C.

Pharm Res. 2012 May;29(5):1219-31. doi: 10.1007/s11095-011-0631-2. Epub 2011 Dec 30.

PMID:
22207207
4.

YB-1 dependent virotherapy in combination with temozolomide as a multimodal therapy approach to eradicate malignant glioma.

Holzmüller R, Mantwill K, Haczek C, Rognoni E, Anton M, Kasajima A, Weichert W, Treue D, Lage H, Schuster T, Schlegel J, Gänsbacher B, Holm PS.

Int J Cancer. 2011 Sep 1;129(5):1265-76. doi: 10.1002/ijc.25783. Epub 2011 Jan 6.

5.

Prostate cancer gene therapy: attempts to innovate.

Kochanek S, Gansbacher B.

Hum Gene Ther. 2010 Jul;21(7):791. doi: 10.1089/hum.2010.1216. No abstract available.

PMID:
20608876
6.

Tetracycline-regulated bone morphogenetic protein 2 gene expression in lentivirally transduced primary rabbit chondrocytes for treatment of cartilage defects.

Wübbenhorst D, Dumler K, Wagner B, Wexel G, Imhoff A, Gansbacher B, Vogt S, Anton M.

Arthritis Rheum. 2010 Jul;62(7):2037-46. doi: 10.1002/art.27461.

7.

Tissue inhibitor of metalloproteinases-1-induced scattered liver metastasis is mediated by host-derived urokinase-type plasminogen activator.

Schrötzlmair F, Kopitz C, Halbgewachs B, Lu F, Algül H, Brünner N, Gänsbacher B, Krüger A.

J Cell Mol Med. 2010 Dec;14(12):2760-70. doi: 10.1111/j.1582-4934.2009.00951.x.

8.

Cancer gene therapy: present and future.

Bonini C, Gansbacher B.

Hum Gene Ther. 2009 Oct;20(10):1100. doi: 10.1089/hum.2009.911. No abstract available.

PMID:
19848596
9.

Tissue engineering of the anterior cruciate ligament-sodium dodecyl sulfate-acellularized and revitalized tendons are inferior to native tendons.

Tischer T, Aryee S, Wexel G, Steinhauser E, Adamczyk C, Eichhorn S, Milz S, Martinek V, Gänsbacher B, Imhoff AB, Vogt S.

Tissue Eng Part A. 2010 Mar;16(3):1031-40. doi: 10.1089/ten.TEA.2009.0043.

PMID:
19845462
10.

Therapeutic vaccination with an interleukin-2-interferon-gamma-secreting allogeneic tumor vaccine in patients with progressive castration-resistant prostate cancer: a phase I/II trial.

Brill TH, Kübler HR, Pohla H, Buchner A, Fend F, Schuster T, van Randenborgh H, Paul R, Kummer T, Plank C, Eisele B, Breul J, Hartung R, Schendel DJ, Gansbacher B.

Hum Gene Ther. 2009 Dec;20(12):1641-51. doi: 10.1089/hum.2009.101.

PMID:
19671000
11.

Combined reporter gene PET and iron oxide MRI for monitoring survival and localization of transplanted cells in the rat heart.

Higuchi T, Anton M, Dumler K, Seidl S, Pelisek J, Saraste A, Welling A, Hofmann F, Oostendorp RA, Gansbacher B, Nekolla SG, Bengel FM, Botnar RM, Schwaiger M.

J Nucl Med. 2009 Jul;50(7):1088-94. doi: 10.2967/jnumed.108.060665. Epub 2009 Jun 12.

12.

Adenovirus-based virotherapy enabled by cellular YB-1 expression in vitro and in vivo.

Rognoni E, Widmaier M, Haczek C, Mantwill K, Holzmüller R, Gansbacher B, Kolk A, Schuster T, Schmid RM, Saur D, Kaszubiak A, Lage H, Holm PS.

Cancer Gene Ther. 2009 Oct;16(10):753-63. doi: 10.1038/cgt.2009.20. Epub 2009 Apr 10.

PMID:
19363467
13.

Physicobiochemical synergism through gene therapy and functional tissue engineering for in vitro chondrogenesis.

Salzmann GM, Nuernberger B, Schmitz P, Anton M, Stoddart MJ, Grad S, Milz S, Tischer T, Vogt S, Gansbacher B, Imhoff AB, Alini M.

Tissue Eng Part A. 2009 Sep;15(9):2513-24. doi: 10.1089/ten.tea.2008.0479.

PMID:
19292668
14.

The influence of the stable expression of BMP2 in fibrin clots on the remodelling and repair of osteochondral defects.

Vogt S, Wexel G, Tischer T, Schillinger U, Ueblacker P, Wagner B, Hensler D, Wilisch J, Geis C, Wübbenhorst D, Aigner J, Gerg M, Krüger A, Salzmann GM, Martinek V, Anton M, Plank C, Imhoff AB, Gansbacher B.

Biomaterials. 2009 Apr;30(12):2385-92. doi: 10.1016/j.biomaterials.2009.01.016. Epub 2009 Jan 31.

PMID:
19185914
15.

Non-viral VEGF(165) gene therapy--magnetofection of acoustically active magnetic lipospheres ('magnetobubbles') increases tissue survival in an oversized skin flap model.

Holzbach T, Vlaskou D, Neshkova I, Konerding MA, Wörtler K, Mykhaylyk O, Gänsbacher B, Machens HG, Plank C, Giunta RE.

J Cell Mol Med. 2010 Mar;14(3):587-99. doi: 10.1111/j.1582-4934.2008.00592.x. Epub 2008 Nov 14.

16.

Searching for the right timing of surgical delay: angiogenesis, vascular endothelial growth factor and perfusion changes in a skin-flap model.

Holzbach T, Neshkova I, Vlaskou D, Konerding MA, Gansbacher B, Biemer E, Giunta RE.

J Plast Reconstr Aesthet Surg. 2009 Nov;62(11):1534-42. doi: 10.1016/j.bjps.2008.05.036. Epub 2008 Sep 23.

PMID:
18815084
17.

Plasminogen activator inhibitor-2, but not cystatin C, inhibits the prometastatic activity of tissue inhibitor of metalloproteinases-1 in the liver.

Kopitz C, Gerg M, Gansbacher B, Krüger A.

Hum Gene Ther. 2008 Oct;19(10):1039-49. doi: 10.1089/hum.2008.078.

PMID:
18681831
18.

Good news on the clinical gene transfer front.

Wilson JM, Gansbacher B, Berns KI, Bosch F, Kay MA, Naldini L, Wei YQ.

Hum Gene Ther. 2008 May;19(5):429-30. doi: 10.1089/hum.2008.0519. No abstract available.

PMID:
18507511
19.

GDNF-transduced Schwann cell grafts enhance regeneration of erectile nerves.

May F, Matiasek K, Vroemen M, Caspers C, Mrva T, Arndt C, Schlenker B, Gais P, Brill T, Buchner A, Blesch A, Hartung R, Stief C, Gansbacher B, Weidner N.

Eur Urol. 2008 Nov;54(5):1179-87. doi: 10.1016/j.eururo.2008.02.003. Epub 2008 Feb 15.

PMID:
18313832
20.

Efficient and stable gene transfer of growth factors into chondrogenic cells and primary articular chondrocytes using a VSV.G pseudotyped retroviral vector.

Vogt S, Ueblacker P, Geis C, Wagner B, Wexel G, Tischer T, Krüger A, Plank C, Anton M, Martinek V, Imhoff AB, Gansbacher B.

Biomaterials. 2008 Mar;29(9):1242-9.

PMID:
18078987
21.

Impact of radiation therapy on the oncolytic adenovirus dl520: implications on the treatment of glioblastoma.

Bieler A, Mantwill K, Holzmüller R, Jürchott K, Kaszubiak A, Stärk S, Glockzin G, Lage H, Grosu AL, Gansbacher B, Holm PS.

Radiother Oncol. 2008 Mar;86(3):419-27. Epub 2007 Oct 29.

PMID:
17967494
22.

In vivo analysis of retroviral gene transfer to chondrocytes within collagen scaffolds for the treatment of osteochondral defects.

Ueblacker P, Wagner B, Vogt S, Salzmann G, Wexel G, Krüger A, Plank C, Brill T, Specht K, Hennig T, Schillinger U, Imhoff AB, Martinek V, Gansbacher B.

Biomaterials. 2007 Oct;28(30):4480-7. Epub 2007 Jul 13.

PMID:
17629939
23.

Allogeneic retrovirally transduced, IL-2- and IFN-gamma-secreting cancer cell vaccine in patients with hormone refractory prostate cancer--a phase I clinical trial.

Brill TH, Kübler HR, von Randenborgh H, Fend F, Pohla H, Breul J, Hartung R, Paul R, Schendel DJ, Gansbacher B.

J Gene Med. 2007 Jul;9(7):547-60.

PMID:
17514769
24.

Inhibition of the multidrug-resistant phenotype by targeting YB-1 with a conditionally oncolytic adenovirus: implications for combinatorial treatment regimen with chemotherapeutic agents.

Mantwill K, Köhler-Vargas N, Bernshausen A, Bieler A, Lage H, Kaszubiak A, Surowiak P, Dravits T, Treiber U, Hartung R, Gansbacher B, Holm PS.

Cancer Res. 2006 Jul 15;66(14):7195-202.

25.

Characterization of the recombinant adenovirus vector AdYB-1: implications for oncolytic vector development.

Glockzin G, Mantwill K, Jurchott K, Bernshausen A, Ladhoff A, Royer HD, Gansbacher B, Holm PS.

J Virol. 2006 Apr;80(8):3904-11.

26.

Novel three-pronged strategy to enhance cancer cell killing in glioblastoma cell lines: histone deacetylase inhibitor, chemotherapy, and oncolytic adenovirus dl520.

Bieler A, Mantwill K, Dravits T, Bernshausen A, Glockzin G, Köhler-Vargas N, Lage H, Gansbacher B, Holm PS.

Hum Gene Ther. 2006 Jan;17(1):55-70.

PMID:
16409125
27.

[Evaluation of perfusion in skin flaps by laser-induced indocyanine green fluorescence].

Holzbach T, Taskov C, Henke J, Busch R, Gänsbacher B, Biemer E, Giunta RE.

Handchir Mikrochir Plast Chir. 2005 Dec;37(6):396-402. German.

PMID:
16388454
28.

[Angiogenesis VEGF165 gene therapy with AdVEGF- a new delay procedure for flaps].

Holzbach T, Taskov C, Neshkova I, Holm PS, Konerding MA, Schams D, Gänsbacher B, Biemer E, Giunta RE.

Handchir Mikrochir Plast Chir. 2005 Dec;37(6):365-74. German.

PMID:
16388451
29.

[Angiogenesis gene therapy - a new innovation push in plastic surgery?].

Giunta RE, Gänsbacher B.

Handchir Mikrochir Plast Chir. 2005 Dec;37(6):363-4. German. No abstract available.

PMID:
16388450
30.

Second generation of meniscus transplantation: in-vivo study with tissue engineered meniscus replacement.

Martinek V, Ueblacker P, Bräun K, Nitschke S, Mannhardt R, Specht K, Gansbacher B, Imhoff AB.

Arch Orthop Trauma Surg. 2006 May;126(4):228-34. Epub 2005 Oct 8.

PMID:
16215722
31.
32.

Non-invasive imaging of cardiac transgene expression with PET: comparison of the human sodium/iodide symporter gene and HSV1-tk as the reporter gene.

Miyagawa M, Anton M, Wagner B, Haubner R, Souvatzoglou M, Gansbacher B, Schwaiger M, Bengel FM.

Eur J Nucl Med Mol Imaging. 2005 Sep;32(9):1108-14.

PMID:
15988610
33.

Nerve replacement strategies for cavernous nerves.

May F, Vroemen M, Matiasek K, Henke J, Brill T, Lehmer A, Apprich M, Erhardt W, Schoeler S, Paul R, Blesch A, Hartung R, Gansbacher B, Weidner N.

Eur Urol. 2005 Sep;48(3):372-8. Review.

PMID:
15964126
34.

[Nerve repair strategies for restoration of erectile function after radical pelvic surgery].

May F, Schoeler S, Vroemen M, Matiasek K, Apprich M, Erhardt W, Hartung R, Gansbacher B, Weidner N.

Urologe A. 2005 Jul;44(7):780-4. Review. German.

PMID:
15952015
35.

Prediction of flap necrosis with laser induced indocyanine green fluorescence in a rat model.

Giunta RE, Holzbach T, Taskov C, Holm PS, Brill T, Busch R, Gansbacher B, Biemer E.

Br J Plast Surg. 2005 Jul;58(5):695-701.

PMID:
15925341
36.

Optimization of radiation controlled gene expression by adenoviral vectors in vitro.

Anton M, Gomaa IE, von Lukowicz T, Molls M, Gansbacher B, Würschmidt F.

Cancer Gene Ther. 2005 Jul;12(7):640-6.

PMID:
15803145
37.

Cardiac reporter gene imaging using the human sodium/iodide symporter gene.

Miyagawa M, Beyer M, Wagner B, Anton M, Spitzweg C, Gansbacher B, Schwaiger M, Bengel FM.

Cardiovasc Res. 2005 Jan 1;65(1):195-202.

PMID:
15621047
38.

[Tissue engineering of erectile nerves].

May F, Weidner N, Matiasek K, Vroemen M, Mrva T, Caspers C, Henke J, Brill T, Lehmer A, Blesch A, Erhardt W, Gänsbacher B, Hartung R.

Urologe A. 2004 Oct;43(10):1242-8. Review. German.

PMID:
15549162
39.

PET of cardiac transgene expression: comparison of 2 approaches based on herpesviral thymidine kinase reporter gene.

Miyagawa M, Anton M, Haubner R, Simoes MV, Städele C, Erhardt W, Reder S, Lehner T, Wagner B, Noll S, Noll B, Grote M, Gambhir SS, Gansbacher B, Schwaiger M, Bengel FM.

J Nucl Med. 2004 Nov;45(11):1917-23.

40.

AdVEGF165 gene transfer increases survival in overdimensioned skin flaps.

Giunta RE, Holzbach T, Taskov C, Holm PS, Konerding MA, Schams D, Biemer E, Gänsbacher B.

J Gene Med. 2005 Mar;7(3):297-306.

PMID:
15515117
41.

Coexpression of herpesviral thymidine kinase reporter gene and VEGF gene for noninvasive monitoring of therapeutic gene transfer: an in vitro evaluation.

Anton M, Wittermann C, Haubner R, Simoes M, Reder S, Essien B, Wagner B, Henke J, Erhardt W, Noll S, Hackett NR, Crystal RG, Schwaiger M, Gansbacher B, Bengel FM.

J Nucl Med. 2004 Oct;45(10):1743-6.

42.

Adenovirus-mediated overexpression of tissue inhibitor of metalloproteinases-1 in the liver: efficient protection against T-cell lymphoma and colon carcinoma metastasis.

Elezkurtaj S, Kopitz C, Baker AH, Perez-Cantó A, Arlt MJ, Khokha R, Gansbacher B, Anton M, Brand K, Krüger A.

J Gene Med. 2004 Nov;6(11):1228-37.

PMID:
15390257
43.

Inducible nonviral gene expression in the treatment of osteochondral defects.

Ueblacker P, Wagner B, Krüger A, Vogt S, DeSantis G, Kennerknecht E, Brill T, Hillemanns M, Salzmann GM, Imhoff AB, Plank C, Gänsbacher B, Martinek V.

Osteoarthritis Cartilage. 2004 Sep;12(9):711-9.

44.

Schwann cell seeded guidance tubes restore erectile function after ablation of cavernous nerves in rats.

May F, Weidner N, Matiasek K, Caspers C, Mrva T, Vroemen M, Henke J, Lehmer A, Schwaibold H, Erhardt W, Gänsbacher B, Hartung R.

J Urol. 2004 Jul;172(1):374-7.

PMID:
15201814
45.

Multidrug-resistant cancer cells facilitate E1-independent adenoviral replication: impact for cancer gene therapy.

Holm PS, Lage H, Bergmann S, Jürchott K, Glockzin G, Bernshausen A, Mantwill K, Ladhoff A, Wichert A, Mymryk JS, Ritter T, Dietel M, Gänsbacher B, Royer HD.

Cancer Res. 2004 Jan 1;64(1):322-8.

46.

Use of the norepinephrine transporter as a reporter gene for non-invasive imaging of genetically modified cells.

Anton M, Wagner B, Haubner R, Bodenstein C, Essien BE, Bönisch H, Schwaiger M, Gansbacher B, Weber WA.

J Gene Med. 2004 Jan;6(1):119-26.

PMID:
14716684
47.

Increase of anti-metastatic efficacy by selectivity- but not affinity-optimization of synthetic serine protease inhibitors.

Banke IJ, Arlt MJ, Pennington C, Kopitz C, Steinmetzer T, Schweinitz A, Gansbacher B, Quigley JP, Edwards DR, Stürzebecher J, Krüger A.

Biol Chem. 2003 Oct-Nov;384(10-11):1515-25.

PMID:
14669995
48.

Noninvasive imaging of transgene expression by use of positron emission tomography in a pig model of myocardial gene transfer.

Bengel FM, Anton M, Richter T, Simoes MV, Haubner R, Henke J, Erhardt W, Reder S, Lehner T, Brandau W, Boekstegers P, Nekolla SG, Gansbacher B, Schwaiger M.

Circulation. 2003 Oct 28;108(17):2127-33. Epub 2003 Oct 6.

PMID:
14530205
49.
50.

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