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Items: 1 to 50 of 86

1.

Clustering, Spatial Distribution, and Phosphorylation of Discoidin Domain Receptors 1 and 2 in Response to Soluble Collagen I.

Yeung DA, Shanker N, Sohail A, Weiss BA, Wang C, Wellmerling J, Das S, Ganju RK, Miller JLC, Herr AB, Fridman R, Agarwal G.

J Mol Biol. 2019 Jan 18;431(2):368-390. doi: 10.1016/j.jmb.2018.11.015. Epub 2018 Nov 17.

PMID:
30458172
2.

Fibroblast-derived CXCL12 promotes breast cancer metastasis by facilitating tumor cell intravasation.

Ahirwar DK, Nasser MW, Ouseph MM, Elbaz M, Cuitiño MC, Kladney RD, Varikuti S, Kaul K, Satoskar AR, Ramaswamy B, Zhang X, Ostrowski MC, Leone G, Ganju RK.

Oncogene. 2018 Aug;37(32):4428-4442. doi: 10.1038/s41388-018-0263-7. Epub 2018 May 3.

PMID:
29720724
3.

STAT1 gene deficient mice develop accelerated breast cancer growth and metastasis which is reduced by IL-17 blockade.

Varikuti S, Oghumu S, Elbaz M, Volpedo G, Ahirwar DK, Alarcon PC, Sperling RH, Moretti E, Pioso MS, Kimble J, Nasser MW, Ganju RK, Terrazas C, Satoskar AR.

Oncoimmunology. 2017 Aug 14;6(11):e1361088. doi: 10.1080/2162402X.2017.1361088. eCollection 2017.

4.

Psoriasin (S100A7): a novel mediator of angiogenesis.

Mishra S, Ahirwar DK, Ganju RK.

Br J Dermatol. 2016 Dec;175(6):1141-1142. doi: 10.1111/bjd.15141. No abstract available.

PMID:
27996128
5.

Enhanced peripheral dopamine impairs post-ischemic healing by suppressing angiotensin receptor type 1 expression in endothelial cells and inhibiting angiogenesis.

Sarkar C, Ganju RK, Pompili VJ, Chakroborty D.

Angiogenesis. 2017 Feb;20(1):97-107. doi: 10.1007/s10456-016-9531-8. Epub 2016 Nov 16.

PMID:
27853962
6.

TRPV2 is a novel biomarker and therapeutic target in triple negative breast cancer.

Elbaz M, Ahirwar D, Xiaoli Z, Zhou X, Lustberg M, Nasser MW, Shilo K, Ganju RK.

Oncotarget. 2016 May 27;9(71):33459-33470. doi: 10.18632/oncotarget.9663. eCollection 2018 Sep 11.

7.

Novel role of cannabinoid receptor 2 in inhibiting EGF/EGFR and IGF-I/IGF-IR pathways in breast cancer.

Elbaz M, Ahirwar D, Ravi J, Nasser MW, Ganju RK.

Oncotarget. 2017 May 2;8(18):29668-29678. doi: 10.18632/oncotarget.9408.

8.

RAGE: A novel target for breast cancer growth and metastasis.

Nasser MW, Ahirwar DK, Ganju RK.

Oncoscience. 2016 Mar 3;3(2):52-3. eCollection 2016. No abstract available.

9.

Endothelial Robo4 suppresses breast cancer growth and metastasis through regulation of tumor angiogenesis.

Zhao H, Ahirwar DK, Oghumu S, Wilkie T, Powell CA, Nasser MW, Satoskar AR, Li DY, Ganju RK.

Mol Oncol. 2016 Feb;10(2):272-81. doi: 10.1016/j.molonc.2015.10.007. Epub 2015 Oct 28.

10.

Cannabinoid receptor-2 agonist inhibits macrophage induced EMT in non-small cell lung cancer by downregulation of EGFR pathway.

Ravi J, Elbaz M, Wani NA, Nasser MW, Ganju RK.

Mol Carcinog. 2016 Dec;55(12):2063-2076. doi: 10.1002/mc.22451. Epub 2016 Jan 6.

PMID:
26741322
11.

Erratum to: miR-29b defines the pro-/anti-proliferative effects of S100A7 in breast cancer.

Zhao H, Wilkie T, Deol Y, Sneh A, Ganju A, Basree M, Nasser MW, Ganju RK.

Mol Cancer. 2015 Nov 16;14(1):195. doi: 10.1186/s12943-015-0451-9. No abstract available.

12.

Non-contact method for directing electrotaxis.

Ahirwar DK, Nasser MW, Jones TH, Sequin EK, West JD, Henthorne TL, Javor J, Kaushik AM, Ganju RK, Subramaniam VV.

Sci Rep. 2015 Jun 9;5:11005. doi: 10.1038/srep11005.

13.

Conditioning solid tumor microenvironment through inflammatory chemokines and S100 family proteins.

Nasser MW, Elbaz M, Ahirwar DK, Ganju RK.

Cancer Lett. 2015 Aug 28;365(1):11-22. doi: 10.1016/j.canlet.2015.05.002. Epub 2015 May 8. Review.

PMID:
25963887
14.

Fatty acid binding protein 5 promotes metastatic potential of triple negative breast cancer cells through enhancing epidermal growth factor receptor stability.

Powell CA, Nasser MW, Zhao H, Wochna JC, Zhang X, Shapiro C, Shilo K, Ganju RK.

Oncotarget. 2015 Mar 20;6(8):6373-85.

15.

Modulation of the tumor microenvironment and inhibition of EGF/EGFR pathway: novel anti-tumor mechanisms of Cannabidiol in breast cancer.

Elbaz M, Nasser MW, Ravi J, Wani NA, Ahirwar DK, Zhao H, Oghumu S, Satoskar AR, Shilo K, Carson WE 3rd, Ganju RK.

Mol Oncol. 2015 Apr;9(4):906-19. doi: 10.1016/j.molonc.2014.12.010. Epub 2015 Jan 19.

16.

miR-29b defines the pro-/anti-proliferative effects of S100A7 in breast cancer.

Zhao H, Wilkie T, Deol Y, Sneh A, Ganju A, Basree M, Nasser MW, Ganju RK.

Mol Cancer. 2015 Jan 27;14:11. doi: 10.1186/s12943-014-0275-z. Erratum in: Mol Cancer. 2015;14(1):195.

17.

RAGE mediates S100A7-induced breast cancer growth and metastasis by modulating the tumor microenvironment.

Nasser MW, Wani NA, Ahirwar DK, Powell CA, Ravi J, Elbaz M, Zhao H, Padilla L, Zhang X, Shilo K, Ostrowski M, Shapiro C, Carson WE 3rd, Ganju RK.

Cancer Res. 2015 Mar 15;75(6):974-85. doi: 10.1158/0008-5472.CAN-14-2161. Epub 2015 Jan 8.

18.

Cannabinoids as therapeutic agents in cancer: current status and future implications.

Chakravarti B, Ravi J, Ganju RK.

Oncotarget. 2014 Aug 15;5(15):5852-72. Review.

19.

C-X-C motif chemokine 12/C-X-C chemokine receptor type 7 signaling regulates breast cancer growth and metastasis by modulating the tumor microenvironment.

Wani N, Nasser MW, Ahirwar DK, Zhao H, Miao Z, Shilo K, Ganju RK.

Breast Cancer Res. 2014 May 29;16(3):R54. doi: 10.1186/bcr3665.

20.
21.

CXCR3 deficiency enhances tumor progression by promoting macrophage M2 polarization in a murine breast cancer model.

Oghumu S, Varikuti S, Terrazas C, Kotov D, Nasser MW, Powell CA, Ganju RK, Satoskar AR.

Immunology. 2014 Sep;143(1):109-19. doi: 10.1111/imm.12293.

22.

CDK4 deficiency promotes genomic instability and enhances Myc-driven lymphomagenesis.

Lu Y, Wu Y, Feng X, Shen R, Wang JH, Fallahi M, Li W, Yang C, Hankey W, Zhao W, Ganju RK, Li MO, Cleveland JL, Zou X.

J Clin Invest. 2014 Apr;124(4):1672-84. doi: 10.1172/JCI63139. Epub 2014 Mar 10.

23.

Slit2-Robo4 pathway modulates lipopolysaccharide-induced endothelial inflammation and its expression is dysregulated during endotoxemia.

Zhao H, Anand AR, Ganju RK.

J Immunol. 2014 Jan 1;192(1):385-93. doi: 10.4049/jimmunol.1302021. Epub 2013 Nov 22.

24.

Reciprocal regulation of microRNA-122 and c-Myc in hepatocellular cancer: role of E2F1 and transcription factor dimerization partner 2.

Wang B, Hsu SH, Wang X, Kutay H, Bid HK, Yu J, Ganju RK, Jacob ST, Yuneva M, Ghoshal K.

Hepatology. 2014 Feb;59(2):555-66. doi: 10.1002/hep.26712. Epub 2013 Dec 20.

25.

Differential role of psoriasin (S100A7) in estrogen receptor α positive and negative breast cancer cells occur through actin remodeling.

Sneh A, Deol YS, Ganju A, Shilo K, Rosol TJ, Nasser MW, Ganju RK.

Breast Cancer Res Treat. 2013 Apr;138(3):727-39. doi: 10.1007/s10549-013-2491-4. Epub 2013 Mar 28.

26.

N-terminal Slit2 inhibits HIV-1 replication by regulating the actin cytoskeleton.

Anand AR, Zhao H, Nagaraja T, Robinson LA, Ganju RK.

Retrovirology. 2013 Jan 7;10:2. doi: 10.1186/1742-4690-10-2.

27.

Activation of the connective tissue growth factor (CTGF)-transforming growth factor β 1 (TGF-β 1) axis in hepatitis C virus-expressing hepatocytes.

Nagaraja T, Chen L, Balasubramanian A, Groopman JE, Ghoshal K, Jacob ST, Leask A, Brigstock DR, Anand AR, Ganju RK.

PLoS One. 2012;7(10):e46526. doi: 10.1371/journal.pone.0046526. Epub 2012 Oct 4.

28.

The adaptor protein SLP-76 regulates HIV-1 release and cell-to-cell transmission in T cells.

Nagaraja T, Anand AR, Zhao H, Ganju RK.

J Immunol. 2012 Mar 15;188(6):2769-77. doi: 10.4049/jimmunol.1102106. Epub 2012 Feb 8.

29.

S100A7 enhances mammary tumorigenesis through upregulation of inflammatory pathways.

Nasser MW, Qamri Z, Deol YS, Ravi J, Powell CA, Trikha P, Schwendener RA, Bai XF, Shilo K, Zou X, Leone G, Wolf R, Yuspa SH, Ganju RK.

Cancer Res. 2012 Feb 1;72(3):604-15. doi: 10.1158/0008-5472.CAN-11-0669. Epub 2011 Dec 12.

30.

Tumor-suppressive effects of psoriasin (S100A7) are mediated through the β-catenin/T cell factor 4 protein pathway in estrogen receptor-positive breast cancer cells.

Deol YS, Nasser MW, Yu L, Zou X, Ganju RK.

J Biol Chem. 2011 Dec 30;286(52):44845-54. doi: 10.1074/jbc.M111.225466. Epub 2011 Oct 20.

31.

Crosstalk between chemokine receptor CXCR4 and cannabinoid receptor CB2 in modulating breast cancer growth and invasion.

Nasser MW, Qamri Z, Deol YS, Smith D, Shilo K, Zou X, Ganju RK.

PLoS One. 2011;6(9):e23901. doi: 10.1371/journal.pone.0023901. Epub 2011 Sep 7.

32.

A novel role for Slit2/Robo1 axis in modulating HIV-1 replication in T cells.

Anand AR, Tirumuru Nagaraja, Ganju RK.

AIDS. 2011 Nov 13;25(17):2105-11. doi: 10.1097/QAD.0b013e32834bab86.

33.

Cdc25A regulates matrix metalloprotease 1 through Foxo1 and mediates metastasis of breast cancer cells.

Feng X, Wu Z, Wu Y, Hankey W, Prior TW, Li L, Ganju RK, Shen R, Zou X.

Mol Cell Biol. 2011 Aug;31(16):3457-71. doi: 10.1128/MCB.05523-11. Epub 2011 Jun 13.

34.

Differential roles of hypoxia inducible factor subunits in multipotential stromal cells under hypoxic condition.

Tamama K, Kawasaki H, Kerpedjieva SS, Guan J, Ganju RK, Sen CK.

J Cell Biochem. 2011 Mar;112(3):804-17. doi: 10.1002/jcb.22961.

35.

Cannabinoid receptors, CB1 and CB2, as novel targets for inhibition of non-small cell lung cancer growth and metastasis.

Preet A, Qamri Z, Nasser MW, Prasad A, Shilo K, Zou X, Groopman JE, Ganju RK.

Cancer Prev Res (Phila). 2011 Jan;4(1):65-75. doi: 10.1158/1940-6207.CAPR-10-0181. Epub 2010 Nov 19.

36.

Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer.

Qamri Z, Preet A, Nasser MW, Bass CE, Leone G, Barsky SH, Ganju RK.

Mol Cancer Ther. 2009 Nov;8(11):3117-29. doi: 10.1158/1535-7163.MCT-09-0448. Epub 2009 Nov 3.

37.

HIV-1 gp120-induced migration of dendritic cells is regulated by a novel kinase cascade involving Pyk2, p38 MAP kinase, and LSP1.

Anand AR, Prasad A, Bradley RR, Deol YS, Nagaraja T, Ren X, Terwilliger EF, Ganju RK.

Blood. 2009 Oct 22;114(17):3588-600. doi: 10.1182/blood-2009-02-206342. Epub 2009 Aug 21.

38.

LPS-induced MCP-1 expression in human microvascular endothelial cells is mediated by the tyrosine kinase, Pyk2 via the p38 MAPK/NF-kappaB-dependent pathway.

Anand AR, Bradley R, Ganju RK.

Mol Immunol. 2009 Feb;46(5):962-8. doi: 10.1016/j.molimm.2008.09.022. Epub 2008 Oct 26.

39.

Medicinal plants and cancer chemoprevention.

Desai AG, Qazi GN, Ganju RK, El-Tamer M, Singh J, Saxena AK, Bedi YS, Taneja SC, Bhat HK.

Curr Drug Metab. 2008 Sep;9(7):581-91. Review.

40.

Underlying pathophysiology of HCV infection in HIV-positive drug users.

Balasubramanian A, Groopman JE, Ganju RK.

J Addict Dis. 2008;27(2):75-82. doi: 10.1300/J069v27n02_09. Review.

41.

Slit-2 induces a tumor-suppressive effect by regulating beta-catenin in breast cancer cells.

Prasad A, Paruchuri V, Preet A, Latif F, Ganju RK.

J Biol Chem. 2008 Sep 26;283(39):26624-33. doi: 10.1074/jbc.M800679200. Epub 2008 Jul 8.

42.

Phytoestrogens and breast cancer prevention: possible mechanisms of action.

Mense SM, Hei TK, Ganju RK, Bhat HK.

Environ Health Perspect. 2008 Apr;116(4):426-33. doi: 10.1289/ehp.10538. Review.

43.

The tyrosine kinase Pyk2 mediates lipopolysaccharide-induced IL-8 expression in human endothelial cells.

Anand AR, Cucchiarini M, Terwilliger EF, Ganju RK.

J Immunol. 2008 Apr 15;180(8):5636-44.

44.

S100A7-downregulation inhibits epidermal growth factor-induced signaling in breast cancer cells and blocks osteoclast formation.

Paruchuri V, Prasad A, McHugh K, Bhat HK, Polyak K, Ganju RK.

PLoS One. 2008 Mar 5;3(3):e1741. doi: 10.1371/journal.pone.0001741.

45.

The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis.

Gupta A, Guerin-Peyrou TG, Sharma GG, Park C, Agarwal M, Ganju RK, Pandita S, Choi K, Sukumar S, Pandita RK, Ludwig T, Pandita TK.

Mol Cell Biol. 2008 Jan;28(1):397-409. Epub 2007 Oct 29.

46.
47.

Slit-2/Robo-1 modulates the CXCL12/CXCR4-induced chemotaxis of T cells.

Prasad A, Qamri Z, Wu J, Ganju RK.

J Leukoc Biol. 2007 Sep;82(3):465-76. Epub 2007 Jun 12.

48.

Signal transducer and activator of transcription factor 1 mediates apoptosis induced by hepatitis C virus and HIV envelope proteins in hepatocytes.

Balasubramanian A, Ganju RK, Groopman JE.

J Infect Dis. 2006 Sep 1;194(5):670-81. Epub 2006 Jul 18.

PMID:
16897667
49.

Cbl and Akt regulate CXCL8-induced and CXCR1- and CXCR2-mediated chemotaxis.

Lane HC, Anand AR, Ganju RK.

Int Immunol. 2006 Aug;18(8):1315-25. Epub 2006 Jun 23.

PMID:
16798838
50.

HIV-1 gp120-mediated apoptosis of T cells is regulated by the membrane tyrosine phosphatase CD45.

Anand AR, Ganju RK.

J Biol Chem. 2006 May 5;281(18):12289-99. Epub 2006 Mar 7.

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