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Items: 18


Current State of and Future Opportunities for Prediction in Microbiome Research: Report from the Mid-Atlantic Microbiome Meet-up in Baltimore on 9 January 2019.

Sakowski E, Uritskiy G, Cooper R, Gomes M, McLaren MR, Meisel JS, Mickol RL, Mintz CD, Mongodin EF, Pop M, Rahman MA, Sanchez A, Timp W, Vela JD, Wolz CM, Zackular JP, Chopyk J, Commichaux S, Davis M, Dluzen D, Ganesan SM, Haruna M, Nasko D, Regan MJ, Sarria S, Shah N, Stacy B, Taylor D, DiRuggiero J, Preheim SP.

mSystems. 2019 Oct 8;4(5). pii: e00392-19. doi: 10.1128/mSystems.00392-19.


Mitochondrial type II NADH dehydrogenase of Plasmodium falciparum (PfNDH2) is dispensable in the asexual blood stages.

Ke H, Ganesan SM, Dass S, Morrisey JM, Pou S, Nilsen A, Riscoe MK, Mather MW, Vaidya AB.

PLoS One. 2019 Apr 9;14(4):e0214023. doi: 10.1371/journal.pone.0214023. eCollection 2019.


Plasmodium Niemann-Pick type C1-related protein is a druggable target required for parasite membrane homeostasis.

Istvan ES, Das S, Bhatnagar S, Beck JR, Owen E, Llinas M, Ganesan SM, Niles JC, Winzeler E, Vaidya AB, Goldberg DE.

Elife. 2019 Mar 19;8. pii: e40529. doi: 10.7554/eLife.40529.


ATG8 Is Essential Specifically for an Autophagy-Independent Function in Apicoplast Biogenesis in Blood-Stage Malaria Parasites.

Walczak M, Ganesan SM, Niles JC, Yeh E.

MBio. 2018 Jan 2;9(1). pii: e02021-17. doi: 10.1128/mBio.02021-17.


The making of a miscreant: tobacco smoke and the creation of pathogen-rich biofilms.

Shah SA, Ganesan SM, Varadharaj S, Dabdoub SM, Walters JD, Kumar PS.

NPJ Biofilms Microbiomes. 2017 Oct 24;3:26. doi: 10.1038/s41522-017-0033-2. eCollection 2017.


Small molecule inhibition of apicomplexan FtsH1 disrupts plastid biogenesis in human pathogens.

Amberg-Johnson K, Hari SB, Ganesan SM, Lorenzi HA, Sauer RT, Niles JC, Yeh E.

Elife. 2017 Aug 18;6. pii: e29865. doi: 10.7554/eLife.29865.


A tale of two risks: smoking, diabetes and the subgingival microbiome.

Ganesan SM, Joshi V, Fellows M, Dabdoub SM, Nagaraja HN, O'Donnell B, Deshpande NR, Kumar PS.

ISME J. 2017 Sep;11(9):2075-2089. doi: 10.1038/ismej.2017.73. Epub 2017 May 23.


Quantification of labile heme in live malaria parasites using a genetically encoded biosensor.

Abshire JR, Rowlands CJ, Ganesan SM, So PT, Niles JC.

Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):E2068-E2076. doi: 10.1073/pnas.1615195114. Epub 2017 Feb 27.


The chaperonin TRiC forms an oligomeric complex in the malaria parasite cytosol.

Spillman NJ, Beck JR, Ganesan SM, Niles JC, Goldberg DE.

Cell Microbiol. 2017 Jun;19(6). doi: 10.1111/cmi.12719. Epub 2017 Jan 24.


Comparative metagenomics reveals taxonomically idiosyncratic yet functionally congruent communities in periodontitis.

Dabdoub SM, Ganesan SM, Kumar PS.

Sci Rep. 2016 Dec 19;6:38993. doi: 10.1038/srep38993.


A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes.

Sidik SM, Huet D, Ganesan SM, Huynh MH, Wang T, Nasamu AS, Thiru P, Saeij JPJ, Carruthers VB, Niles JC, Lourido S.

Cell. 2016 Sep 8;166(6):1423-1435.e12. doi: 10.1016/j.cell.2016.08.019. Epub 2016 Sep 2.


Synthetic RNA-protein modules integrated with native translation mechanisms to control gene expression in malaria parasites.

Ganesan SM, Falla A, Goldfless SJ, Nasamu AS, Niles JC.

Nat Commun. 2016 Mar 1;7:10727. doi: 10.1038/ncomms10727.


Genetic investigation of tricarboxylic acid metabolism during the Plasmodium falciparum life cycle.

Ke H, Lewis IA, Morrisey JM, McLean KJ, Ganesan SM, Painter HJ, Mather MW, Jacobs-Lorena M, LlinĂ¡s M, Vaidya AB.

Cell Rep. 2015 Apr 7;11(1):164-74. doi: 10.1016/j.celrep.2015.03.011. Epub 2015 Apr 2.


An integrated strategy for efficient vector construction and multi-gene expression in Plasmodium falciparum.

Wagner JC, Goldfless SJ, Ganesan SM, Lee MC, Fidock DA, Niles JC.

Malar J. 2013 Oct 26;12:373. doi: 10.1186/1475-2875-12-373.


Mitochondrial RNA polymerase is an essential enzyme in erythrocytic stages of Plasmodium falciparum.

Ke H, Morrisey JM, Ganesan SM, Mather MW, Vaidya AB.

Mol Biochem Parasitol. 2012 Sep;185(1):48-51. doi: 10.1016/j.molbiopara.2012.05.001. Epub 2012 May 26.


ATP synthase complex of Plasmodium falciparum: dimeric assembly in mitochondrial membranes and resistance to genetic disruption.

Balabaskaran Nina P, Morrisey JM, Ganesan SM, Ke H, Pershing AM, Mather MW, Vaidya AB.

J Biol Chem. 2011 Dec 2;286(48):41312-22. doi: 10.1074/jbc.M111.290973. Epub 2011 Oct 7.


Variation among Plasmodium falciparum strains in their reliance on mitochondrial electron transport chain function.

Ke H, Morrisey JM, Ganesan SM, Painter HJ, Mather MW, Vaidya AB.

Eukaryot Cell. 2011 Aug;10(8):1053-61. doi: 10.1128/EC.05049-11. Epub 2011 Jun 17.


Yeast dihydroorotate dehydrogenase as a new selectable marker for Plasmodium falciparum transfection.

Ganesan SM, Morrisey JM, Ke H, Painter HJ, Laroiya K, Phillips MA, Rathod PK, Mather MW, Vaidya AB.

Mol Biochem Parasitol. 2011 May;177(1):29-34. doi: 10.1016/j.molbiopara.2011.01.004. Epub 2011 Jan 18.

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