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Items: 1 to 50 of 159

1.

The non-psychoactive phytocannabinoid cannabidiol (CBD) attenuates pro-inflammatory mediators, T cell infiltration, and thermal sensitivity following spinal cord injury in mice.

Li H, Kong W, Chambers CR, Yu D, Ganea D, Tuma RF, Ward SJ.

Cell Immunol. 2018 Jul;329:1-9. doi: 10.1016/j.cellimm.2018.02.016. Epub 2018 Mar 8.

PMID:
29784129
2.

Phase III Trial of Ipilimumab Combined With Paclitaxel and Carboplatin in Advanced Squamous Non-Small-Cell Lung Cancer.

Govindan R, Szczesna A, Ahn MJ, Schneider CP, Gonzalez Mella PF, Barlesi F, Han B, Ganea DE, Von Pawel J, Vladimirov V, Fadeeva N, Lee KH, Kurata T, Zhang L, Tamura T, Postmus PE, Jassem J, O'Byrne K, Kopit J, Li M, Tschaika M, Reck M.

J Clin Oncol. 2017 Oct 20;35(30):3449-3457. doi: 10.1200/JCO.2016.71.7629. Epub 2017 Aug 30.

PMID:
28854067
3.

Prostaglandin E2 inhibits Tr1 cell differentiation through suppression of c-Maf.

Hooper KM, Kong W, Ganea D.

PLoS One. 2017 Jun 12;12(6):e0179184. doi: 10.1371/journal.pone.0179184. eCollection 2017.

4.

Protein tyrosine phosphatase σ regulates autoimmune encephalomyelitis development.

Ohtake Y, Kong W, Hussain R, Horiuchi M, Tremblay ML, Ganea D, Li S.

Brain Behav Immun. 2017 Oct;65:111-124. doi: 10.1016/j.bbi.2017.05.018. Epub 2017 May 27.

PMID:
28559011
5.

Prostaglandin E2 Inhibition of IL-27 Production in Murine Dendritic Cells: A Novel Mechanism That Involves IRF1.

Hooper KM, Yen JH, Kong W, Rahbari KM, Kuo PC, Gamero AM, Ganea D.

J Immunol. 2017 Feb 15;198(4):1521-1530. doi: 10.4049/jimmunol.1601073. Epub 2017 Jan 6.

6.

Interferon-β Modulates Inflammatory Response in Cerebral Ischemia.

Kuo PC, Scofield BA, Yu IC, Chang FL, Ganea D, Yen JH.

J Am Heart Assoc. 2016 Jan 8;5(1). pii: e002610. doi: 10.1161/JAHA.115.002610.

7.

The natural dual cyclooxygenase and 5-lipoxygenase inhibitor flavocoxid is protective in EAE through effects on Th1/Th17 differentiation and macrophage/microglia activation.

Kong W, Hooper KM, Ganea D.

Brain Behav Immun. 2016 Mar;53:59-71. doi: 10.1016/j.bbi.2015.11.002. Epub 2015 Nov 2.

PMID:
26541818
8.

Differential effects of IFN-β on IL-12, IL-23, and IL-10 expression in TLR-stimulated dendritic cells.

Yen JH, Kong W, Hooper KM, Emig F, Rahbari KM, Kuo PC, Scofield BA, Ganea D.

J Leukoc Biol. 2015 Nov;98(5):689-702. doi: 10.1189/jlb.3HI0914-453R. Epub 2015 Jun 9.

9.

A selective cannabinoid CB2 agonist attenuates damage and improves memory retention following stroke in mice.

Ronca RD, Myers AM, Ganea D, Tuma RF, Walker EA, Ward SJ.

Life Sci. 2015 Oct 1;138:72-7. doi: 10.1016/j.lfs.2015.05.005. Epub 2015 May 30.

10.

The Membrane Proximal Region of AMPA Receptors in Lateral Amygdala is Essential for Fear Memory Formation.

Ganea DA, Dines M, Basu S, Lamprecht R.

Neuropsychopharmacology. 2015 Nov;40(12):2727-35. doi: 10.1038/npp.2015.121. Epub 2015 Apr 27.

11.

The neuropeptide vasoactive intestinal peptide: direct effects on immune cells and involvement in inflammatory and autoimmune diseases.

Ganea D, Hooper KM, Kong W.

Acta Physiol (Oxf). 2015 Feb;213(2):442-52. doi: 10.1111/apha.12427. Epub 2014 Dec 11. Review.

12.

Members of the novel UBASH3/STS/TULA family of cellular regulators suppress T-cell-driven inflammatory responses in vivo.

Newman TN, Liverani E, Ivanova E, Russo GL, Carpino N, Ganea D, Safadi F, Kunapuli SP, Tsygankov AY.

Immunol Cell Biol. 2014 Nov;92(10):837-50. doi: 10.1038/icb.2014.60. Epub 2014 Jul 22.

PMID:
25047644
13.

Selective CB2 receptor activation ameliorates EAE by reducing Th17 differentiation and immune cell accumulation in the CNS.

Kong W, Li H, Tuma RF, Ganea D.

Cell Immunol. 2014 Jan;287(1):1-17. doi: 10.1016/j.cellimm.2013.11.002. Epub 2013 Nov 14.

14.

Adrenomedullin protects from experimental autoimmune encephalomyelitis at multiple levels.

Pedreño M, Morell M, Robledo G, Souza-Moreira L, Forte-Lago I, Caro M, O'Valle F, Ganea D, Gonzalez-Rey E.

Brain Behav Immun. 2014 Mar;37:152-63. doi: 10.1016/j.bbi.2013.11.021. Epub 2013 Dec 7.

15.

ABL1 in thalamus is associated with safety but not fear learning.

Habib MR, Ganea DA, Katz IK, Lamprecht R.

Front Syst Neurosci. 2013 Mar 26;7:5. doi: 10.3389/fnsys.2013.00005. eCollection 2013.

16.

Higher susceptibility to experimental autoimmune encephalomyelitis in Muc1-deficient mice is associated with increased Th1/Th17 responses.

Yen JH, Xu S, Park YS, Ganea D, Kim KC.

Brain Behav Immun. 2013 Mar;29:70-81. doi: 10.1016/j.bbi.2012.12.004. Epub 2012 Dec 20.

17.

Microbial amyloids induce interleukin 17A (IL-17A) and IL-22 responses via Toll-like receptor 2 activation in the intestinal mucosa.

Nishimori JH, Newman TN, Oppong GO, Rapsinski GJ, Yen JH, Biesecker SG, Wilson RP, Butler BP, Winter MG, Tsolis RM, Ganea D, Tükel Ç.

Infect Immun. 2012 Dec;80(12):4398-408. doi: 10.1128/IAI.00911-12. Epub 2012 Oct 1.

18.

Prostaglandin E2-induced IL-23p19 subunit is regulated by cAMP-responsive element-binding protein and C/AATT enhancer-binding protein β in bone marrow-derived dendritic cells.

Kocieda VP, Adhikary S, Emig F, Yen JH, Toscano MG, Ganea D.

J Biol Chem. 2012 Oct 26;287(44):36922-35. doi: 10.1074/jbc.M112.402958. Epub 2012 Sep 12.

19.

Signaling through cannabinoid receptor 2 suppresses murine dendritic cell migration by inhibiting matrix metalloproteinase 9 expression.

Adhikary S, Kocieda VP, Yen JH, Tuma RF, Ganea D.

Blood. 2012 Nov 1;120(18):3741-9. doi: 10.1182/blood-2012-06-435362. Epub 2012 Sep 12.

20.

Unique effects of compounds active at both cannabinoid and serotonin receptors during stroke.

Zhang M, Mahadevan A, Amere M, Li H, Ganea D, Tuma RF.

Transl Stroke Res. 2012 Sep;3(3):348-56. doi: 10.1007/s12975-012-0197-2. Epub 2012 Jul 26.

PMID:
24323810
21.

Vasoactive intestinal peptide: a neuropeptide with pleiotropic immune functions.

Delgado M, Ganea D.

Amino Acids. 2013 Jul;45(1):25-39. doi: 10.1007/s00726-011-1184-8. Epub 2011 Dec 3. Review.

22.

Modulation of inflammatory responses by a cannabinoid-2-selective agonist after spinal cord injury.

Adhikary S, Li H, Heller J, Skarica M, Zhang M, Ganea D, Tuma RF.

J Neurotrauma. 2011 Dec;28(12):2417-27. doi: 10.1089/neu.2011.1853. Epub 2011 Oct 4.

23.

Prostaglandin E2 induces matrix metalloproteinase 9 expression in dendritic cells through two independent signaling pathways leading to activator protein 1 (AP-1) activation.

Yen JH, Kocieda VP, Jing H, Ganea D.

J Biol Chem. 2011 Nov 11;286(45):38913-23. doi: 10.1074/jbc.M111.252932. Epub 2011 Sep 22.

25.

Cecal ligation puncture procedure.

Toscano MG, Ganea D, Gamero AM.

J Vis Exp. 2011 May 7;(51). pii: 2860. doi: 10.3791/2860.

26.
27.

Neuropeptides: keeping the balance between pathogen immunity and immune tolerance.

Gonzalez-Rey E, Ganea D, Delgado M.

Curr Opin Pharmacol. 2010 Aug;10(4):473-81. doi: 10.1016/j.coph.2010.03.003. Review.

28.

IFN-beta inhibits dendritic cell migration through STAT-1-mediated transcriptional suppression of CCR7 and matrix metalloproteinase 9.

Yen JH, Kong W, Ganea D.

J Immunol. 2010 Apr 1;184(7):3478-86. doi: 10.4049/jimmunol.0902542. Epub 2010 Feb 26.

29.

Docosahexaenoic acid prevents dendritic cell maturation and in vitro and in vivo expression of the IL-12 cytokine family.

Kong W, Yen JH, Vassiliou E, Adhikary S, Toscano MG, Ganea D.

Lipids Health Dis. 2010 Feb 1;9:12. doi: 10.1186/1476-511X-9-12.

30.

Dendritic cells transduced with lentiviral vectors expressing VIP differentiate into VIP-secreting tolerogenic-like DCs.

Toscano MG, Delgado M, Kong W, Martin F, Skarica M, Ganea D.

Mol Ther. 2010 May;18(5):1035-45. doi: 10.1038/mt.2009.293. Epub 2010 Jan 12.

31.

Interferon beta induces mature dendritic cell apoptosis through caspase-11/caspase-3 activation.

Yen JH, Ganea D.

Blood. 2009 Aug 13;114(7):1344-54. doi: 10.1182/blood-2008-12-196592. Epub 2009 Jun 16.

32.

CB2 receptor activation attenuates microcirculatory dysfunction during cerebral ischemic/reperfusion injury.

Zhang M, Adler MW, Abood ME, Ganea D, Jallo J, Tuma RF.

Microvasc Res. 2009 Jun;78(1):86-94. doi: 10.1016/j.mvr.2009.03.005. Epub 2009 Mar 28.

33.

Modulation of cannabinoid receptor activation as a neuroprotective strategy for EAE and stroke.

Zhang M, Martin BR, Adler MW, Razdan RJ, Kong W, Ganea D, Tuma RF.

J Neuroimmune Pharmacol. 2009 Jun;4(2):249-59. doi: 10.1007/s11481-009-9148-4. Epub 2009 Mar 3. Review.

34.

The combination of selective inhibition of the cannabinoid CB1 receptor and activation of the cannabinoid CB2 receptor yields improved attenuation of motor and autonomic deficits in a mouse model of spinal cord injury.

Heller JE, Baty DE, Zhang M, Li H, Adler M, Ganea D, Gaughan J, Loftus CM, Jallo JI, Tuma RF.

Clin Neurosurg. 2009;56:84-92. No abstract available.

PMID:
20214038
35.
36.

Anti-inflammatory neuropeptides: a new class of endogenous immunoregulatory agents.

Delgado M, Ganea D.

Brain Behav Immun. 2008 Nov;22(8):1146-51. doi: 10.1016/j.bbi.2008.06.001. Epub 2008 Jun 14. Review.

38.

Modulation of the balance between cannabinoid CB(1) and CB(2) receptor activation during cerebral ischemic/reperfusion injury.

Zhang M, Martin BR, Adler MW, Razdan RK, Ganea D, Tuma RF.

Neuroscience. 2008 Mar 27;152(3):753-60. doi: 10.1016/j.neuroscience.2008.01.022. Epub 2008 Jan 25.

39.

Cannabinoid CB2 receptor activation attenuates motor and autonomic function deficits in a mouse model of spinal cord injury.

Baty DE, Zhang M, Li H, Erb CJ, Adler MW, Ganea D, Loftus CM, Jallo JI, Tuma RF.

Clin Neurosurg. 2008;55:172-7. No abstract available.

PMID:
19248685
40.

A novel mechanism for immunosuppression: from neuropeptides to regulatory T cells.

Ganea D, Gonzalez-Rey E, Delgado M.

J Neuroimmune Pharmacol. 2006 Dec;1(4):400-9. Epub 2006 Oct 10. Review.

PMID:
18040812
41.

PGE2-induced metalloproteinase-9 is essential for dendritic cell migration.

Yen JH, Khayrullina T, Ganea D.

Blood. 2008 Jan 1;111(1):260-70. Epub 2007 Oct 9.

42.

Neuropeptides: active participants in regulation of immune responses in the CNS and periphery.

Ganea D.

Brain Behav Immun. 2008 Jan;22(1):33-4. Epub 2007 Aug 15. No abstract available.

43.

Prostaglandin E2 exacerbates collagen-induced arthritis in mice through the inflammatory interleukin-23/interleukin-17 axis.

Sheibanie AF, Khayrullina T, Safadi FF, Ganea D.

Arthritis Rheum. 2007 Aug;56(8):2608-19.

44.

The proinflammatory effect of prostaglandin E2 in experimental inflammatory bowel disease is mediated through the IL-23-->IL-17 axis.

Sheibanie AF, Yen JH, Khayrullina T, Emig F, Zhang M, Tuma R, Ganea D.

J Immunol. 2007 Jun 15;178(12):8138-47.

45.
46.

VIP protects Th2 cells by downregulating granzyme B expression.

Sharma V, Delgado M, Ganea D.

Ann N Y Acad Sci. 2006 Jul;1070:540-4.

PMID:
16888222
47.

VIP prevents experimental multiple sclerosis by downregulating both inflammatory and autoimmune components of the disease.

Fernandez-Martin A, Gonzalez-Rey E, Chorny A, Martin J, Pozo D, Ganea D, Delgado M.

Ann N Y Acad Sci. 2006 Jul;1070:276-81.

PMID:
16888178
48.

Vasoactive intestinal peptide: the dendritic cell --> regulatory T cell axis.

Delgado M, Gonzalez-Rey E, Ganea D.

Ann N Y Acad Sci. 2006 Jul;1070:233-8.

PMID:
16888172
50.

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