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Items: 17

1.

HIV-1 capsid is involved in post-nuclear entry steps.

Chen NY, Zhou L, Gane PJ, Opp S, Ball NJ, Nicastro G, Zufferey M, Buffone C, Luban J, Selwood D, Diaz-Griffero F, Taylor I, Fassati A.

Retrovirology. 2016 Apr 23;13:28. doi: 10.1186/s12977-016-0262-0.

2.

2- and 3-substituted imidazo[1,2-a]pyrazines as inhibitors of bacterial type IV secretion.

Sayer JR, Walldén K, Pesnot T, Campbell F, Gane PJ, Simone M, Koss H, Buelens F, Boyle TP, Selwood DL, Waksman G, Tabor AB.

Bioorg Med Chem. 2014 Nov 15;22(22):6459-70. doi: 10.1016/j.bmc.2014.09.036. Epub 2014 Sep 28.

3.

Endothelial C-type natriuretic peptide maintains vascular homeostasis.

Moyes AJ, Khambata RS, Villar I, Bubb KJ, Baliga RS, Lumsden NG, Xiao F, Gane PJ, Rebstock AS, Worthington RJ, Simone MI, Mota F, Rivilla F, Vallejo S, Peiró C, Sánchez Ferrer CF, Djordjevic S, Caulfield MJ, MacAllister RJ, Selwood DL, Ahluwalia A, Hobbs AJ.

J Clin Invest. 2014 Sep;124(9):4039-51. doi: 10.1172/JCI74281. Epub 2014 Aug 8.

4.

Suppression of type 1 pilus assembly in uropathogenic Escherichia coli by chemical inhibition of subunit polymerization.

Lo AW, Van de Water K, Gane PJ, Chan AW, Steadman D, Stevens K, Selwood DL, Waksman G, Remaut H.

J Antimicrob Chemother. 2014 Apr;69(4):1017-26. doi: 10.1093/jac/dkt467. Epub 2013 Dec 8.

5.

Molecular fields in ligand discovery.

Gane PJ, Chan AW.

Methods Mol Biol. 2013;1008:479-99. doi: 10.1007/978-1-62703-398-5_18.

PMID:
23729264
6.

SIFTS: Structure Integration with Function, Taxonomy and Sequences resource.

Velankar S, Dana JM, Jacobsen J, van Ginkel G, Gane PJ, Luo J, Oldfield TJ, O'Donovan C, Martin MJ, Kleywegt GJ.

Nucleic Acids Res. 2013 Jan;41(Database issue):D483-9. doi: 10.1093/nar/gks1258. Epub 2012 Nov 29.

7.

Gyrase B inhibitor impairs HIV-1 replication by targeting Hsp90 and the capsid protein.

Vozzolo L, Loh B, Gane PJ, Tribak M, Zhou L, Anderson I, Nyakatura E, Jenner RG, Selwood D, Fassati A.

J Biol Chem. 2010 Dec 10;285(50):39314-28. doi: 10.1074/jbc.M110.155275. Epub 2010 Oct 11.

8.

Oxadiazolylindazole sodium channel modulators are neuroprotective toward hippocampal neurones.

Clutterbuck LA, Posada CG, Visintin C, Riddall DR, Lancaster B, Gane PJ, Garthwaite J, Selwood DL.

J Med Chem. 2009 May 14;52(9):2694-707. doi: 10.1021/jm801180p.

PMID:
19341281
9.

Discovery of inhibitors of the pentein superfamily protein dimethylarginine dimethylaminohydrolase (DDAH), by virtual screening and hit analysis.

Hartzoulakis B, Rossiter S, Gill H, O'Hara B, Steinke E, Gane PJ, Hurtado-Guerrero R, Leiper JM, Vallance P, Rust JM, Selwood DL.

Bioorg Med Chem Lett. 2007 Jul 15;17(14):3953-6. Epub 2007 May 3.

PMID:
17543521
10.

Recent advances in structure-based rational drug design.

Gane PJ, Dean PM.

Curr Opin Struct Biol. 2000 Aug;10(4):401-4. Review.

PMID:
10981625
12.

Experimental and theoretical analyses of the domain architecture of mammalian protein disulphide-isomerase.

Freedman RB, Gane PJ, Hawkins HC, Hlodan R, McLaughlin SH, Parry JW.

Biol Chem. 1998 Mar;379(3):321-8.

PMID:
9563828
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15.

A model for prion protein dimerisation based on alpha-helical packing.

Warwicker J, Gane PJ.

Biochem Biophys Res Commun. 1996 Sep 24;226(3):777-82.

PMID:
8831689
16.

Calculation of Cys 30 delta pKa's and oxidising power for DsbA mutants.

Warwicker J, Gane PJ.

FEBS Lett. 1996 Apr 29;385(1-2):105-8.

17.

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