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Items: 1 to 50 of 348

1.

Allopurinol treatment adversely impacts left ventricular mass regression in patients with well-controlled hypertension.

Gingles CR, Symon R, Gandy SJ, Struthers AD, Houston G, MacDonald TM, Lang CC, Donnan PT, George J.

J Hypertens. 2019 Jul 1. doi: 10.1097/HJH.0000000000002189. [Epub ahead of print]

PMID:
31268872
2.

Relationship of traumatic brain injury to chronic mental health problems and dementia in military veterans.

Elder GA, Ehrlich ME, Gandy S.

Neurosci Lett. 2019 May 26;707:134294. doi: 10.1016/j.neulet.2019.134294. [Epub ahead of print] Review.

PMID:
31141716
3.

A randomized controlled trial of metformin on left ventricular hypertrophy in patients with coronary artery disease without diabetes: the MET-REMODEL trial.

Mohan M, Al-Talabany S, McKinnie A, Mordi IR, Singh JSS, Gandy SJ, Baig F, Hussain MS, Bhalraam U, Khan F, Choy AM, Matthew S, Houston JG, Struthers AD, George J, Lang CC.

Eur Heart J. 2019 Apr 17. pii: ehz203. doi: 10.1093/eurheartj/ehz203. [Epub ahead of print]

PMID:
30993313
4.

Posttraumatic stress disorder and total amyloid burden and amyloid-β 42/40 ratios in plasma: Results from a pilot study of World Trade Center responders.

Clouston SAP, Deri Y, Diminich E, Kew R, Kotov R, Stewart C, Yang X, Gandy S, Sano M, Bromet EJ, Luft BJ.

Alzheimers Dement (Amst). 2019 Feb 28;11:216-220. doi: 10.1016/j.dadm.2019.01.003. eCollection 2019 Dec.

5.

Unexpected systemic phenotypes result from focal combined deficiencies of forebrain insulin receptor/IGF-1 receptor signaling.

Gandy S, Huffman DM.

Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):5852-5854. doi: 10.1073/pnas.1901970116. Epub 2019 Mar 11. No abstract available.

PMID:
30858326
6.

Low-level blast exposure disrupts gliovascular and neurovascular connections and induces a chronic vascular pathology in rat brain.

Gama Sosa MA, De Gasperi R, Perez Garcia GS, Perez GM, Searcy C, Vargas D, Spencer A, Janssen PL, Tschiffely AE, McCarron RM, Ache B, Manoharan R, Janssen WG, Tappan SJ, Hanson RW, Gandy S, Hof PR, Ahlers ST, Elder GA.

Acta Neuropathol Commun. 2019 Jan 9;7(1):6. doi: 10.1186/s40478-018-0647-5.

7.

Correction: Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden.

Haure-Mirande JV, Wang M, Audrain M, Fanutza T, Kim SH, Heja S, Readhead B, Dudley JT, Blitzer RD, Schadt EE, Zhang B, Gandy S, Ehrlich ME.

Mol Psychiatry. 2019 Mar;24(3):472. doi: 10.1038/s41380-018-0301-4.

PMID:
30464330
8.
9.

Parahippocampal gyrus expression of endothelial and insulin receptor signaling pathway genes is modulated by Alzheimer's disease and normalized by treatment with anti-diabetic agents.

Katsel P, Roussos P, Beeri MS, Gama-Sosa MA, Gandy S, Khan S, Haroutunian V.

PLoS One. 2018 Nov 1;13(11):e0206547. doi: 10.1371/journal.pone.0206547. eCollection 2018.

10.

Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden.

Haure-Mirande JV, Wang M, Audrain M, Fanutza T, Kim SH, Heja S, Readhead B, Dudley JT, Blitzer RD, Schadt EE, Zhang B, Gandy S, Ehrlich ME.

Mol Psychiatry. 2019 Mar;24(3):431-446. doi: 10.1038/s41380-018-0255-6. Epub 2018 Oct 3. Erratum in: Mol Psychiatry. 2018 Nov 21;:.

11.

Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in a tauopathy mouse model reduces C1q and normalizes clinical phenotype while increasing spread and state of phosphorylation of tau.

Audrain M, Haure-Mirande JV, Wang M, Kim SH, Fanutza T, Chakrabarty P, Fraser P, St George-Hyslop PH, Golde TE, Blitzer RD, Schadt EE, Zhang B, Ehrlich ME, Gandy S.

Mol Psychiatry. 2018 Oct 3. doi: 10.1038/s41380-018-0258-3. [Epub ahead of print]

12.

Blast-induced "PTSD": Evidence from an animal model.

Perez-Garcia G, Gama Sosa MA, De Gasperi R, Tschiffely AE, McCarron RM, Hof PR, Gandy S, Ahlers ST, Elder GA.

Neuropharmacology. 2019 Feb;145(Pt B):220-229. doi: 10.1016/j.neuropharm.2018.09.023. Epub 2018 Sep 15. Review.

PMID:
30227150
13.

The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease.

Wang M, Beckmann ND, Roussos P, Wang E, Zhou X, Wang Q, Ming C, Neff R, Ma W, Fullard JF, Hauberg ME, Bendl J, Peters MA, Logsdon B, Wang P, Mahajan M, Mangravite LM, Dammer EB, Duong DM, Lah JJ, Seyfried NT, Levey AI, Buxbaum JD, Ehrlich M, Gandy S, Katsel P, Haroutunian V, Schadt E, Zhang B.

Sci Data. 2018 Sep 11;5:180185. doi: 10.1038/sdata.2018.185.

14.

Non-contrast MRI methods as a tool for the pre-operative assessment and surveillance of the arterio-venous fistula for haemodialysis.

MacDonald CJ, Gandy S, Avison ECM, Matthew S, Ross R, Houston JG.

MAGMA. 2018 Dec;31(6):735-745. doi: 10.1007/s10334-018-0700-1. Epub 2018 Aug 21.

PMID:
30132298
15.

Morphological and hemodynamical alterations in brachial artery and cephalic vein. An image-based study for preoperative assessment for vascular access creation.

Aristokleous N, Houston JG, Browne LD, Broderick SP, Kokkalis E, Gandy SJ, Walsh MT.

Int J Numer Method Biomed Eng. 2018 Nov;34(11):e3136. doi: 10.1002/cnm.3136. Epub 2018 Sep 5.

PMID:
30070048
16.

iPSC-derived familial Alzheimer's PSEN2 N141I cholinergic neurons exhibit mutation-dependent molecular pathology corrected by insulin signaling.

Moreno CL, Della Guardia L, Shnyder V, Ortiz-Virumbrales M, Kruglikov I, Zhang B, Schadt EE, Tanzi RE, Noggle S, Buettner C, Gandy S.

Mol Neurodegener. 2018 Jun 26;13(1):33. doi: 10.1186/s13024-018-0265-5.

17.

Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus.

Readhead B, Haure-Mirande JV, Funk CC, Richards MA, Shannon P, Haroutunian V, Sano M, Liang WS, Beckmann ND, Price ND, Reiman EM, Schadt EE, Ehrlich ME, Gandy S, Dudley JT.

Neuron. 2018 Jul 11;99(1):64-82.e7. doi: 10.1016/j.neuron.2018.05.023. Epub 2018 Jun 21.

18.

Prevalence and Distribution of Atherosclerosis in a Low- to Intermediate-Risk Population: Assessment with Whole-Body MR Angiography.

Lambert MA, Weir-McCall JR, Salsano M, Gandy SJ, Levin D, Cavin I, Littleford R, MacFarlane JA, Matthew SZ, Nicholas RS, Struthers AD, Sullivan F, Henderson SA, White RD, Belch JJF, Houston JG.

Radiology. 2018 Jun;287(3):795-804. doi: 10.1148/radiol.2018171609. Epub 2018 May 1.

19.

Psychological variables implied in the therapeutic effect of ayahuasca: A contextual approach.

Franquesa A, Sainz-Cort A, Gandy S, Soler J, Alcázar-Córcoles MÁ, Bouso JC.

Psychiatry Res. 2018 Jun;264:334-339. doi: 10.1016/j.psychres.2018.04.012. Epub 2018 Apr 4.

PMID:
29674223
20.

Quantitative parameters in dynamic contrast-enhanced magnetic resonance imaging for the detection and characterization of prostate cancer.

Wei C, Jin B, Szewczyk-Bieda M, Gandy S, Lang S, Zhang Y, Huang Z, Nabi G.

Oncotarget. 2018 Mar 23;9(22):15997-16007. doi: 10.18632/oncotarget.24652. eCollection 2018 Mar 23.

21.

Integrated biology approach reveals molecular and pathological interactions among Alzheimer's Aβ42, Tau, TREM2, and TYROBP in Drosophila models.

Sekiya M, Wang M, Fujisaki N, Sakakibara Y, Quan X, Ehrlich ME, De Jager PL, Bennett DA, Schadt EE, Gandy S, Ando K, Zhang B, Iijima KM.

Genome Med. 2018 Mar 29;10(1):26. doi: 10.1186/s13073-018-0530-9.

22.

Quantitative MRI evaluation of whole abdomen adipose tissue volumes in healthy volunteers-validation of technique and implications for clinical studies.

Marzetti M, Brunton T, McCreight L, Pearson E, Docherty S, Gandy SJ.

Br J Radiol. 2018 Jul;91(1087):20180025. doi: 10.1259/bjr.20180025. Epub 2018 May 17.

23.

Alzheimer's Disease: A Journey from Amyloid Peptides and Oxidative Stress, to Biomarker Technologies and Disease Prevention Strategies-Gains from AIBL and DIAN Cohort Studies.

Martins RN, Villemagne V, Sohrabi HR, Chatterjee P, Shah TM, Verdile G, Fraser P, Taddei K, Gupta VB, Rainey-Smith SR, Hone E, Pedrini S, Lim WL, Martins I, Frost S, Gupta S, O'Bryant S, Rembach A, Ames D, Ellis K, Fuller SJ, Brown B, Gardener SL, Fernando B, Bharadwaj P, Burnham S, Laws SM, Barron AM, Goozee K, Wahjoepramono EJ, Asih PR, Doecke JD, Salvado O, Bush AI, Rowe CC, Gandy SE, Masters CL.

J Alzheimers Dis. 2018;62(3):965-992. doi: 10.3233/JAD-171145. Review.

24.

PTSD-Related Behavioral Traits in a Rat Model of Blast-Induced mTBI Are Reversed by the mGluR2/3 Receptor Antagonist BCI-838.

Perez-Garcia G, De Gasperi R, Gama Sosa MA, Perez GM, Otero-Pagan A, Tschiffely A, McCarron RM, Ahlers ST, Elder GA, Gandy S.

eNeuro. 2018 Jan 30;5(1). pii: ENEURO.0357-17.2018. doi: 10.1523/ENEURO.0357-17.2018. eCollection 2018 Jan-Feb.

25.

Systemic arteriosclerosis is associated with left ventricular remodeling but not atherosclerosis: a TASCFORCE study.

Weir-McCall JR, Lambert M, Gandy SJ, Belch JJF, Cavin I, Henderson SA, Littleford R, Macfarlane JA, Matthew SZ, Stephen Nicholas R, Struthers AD, Sullivan F, White RD, Graeme Houston J.

J Cardiovasc Magn Reson. 2018 Jan 30;20(1):7. doi: 10.1186/s12968-018-0428-0.

26.

Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums.

Arnold SE, Arvanitakis Z, Macauley-Rambach SL, Koenig AM, Wang HY, Ahima RS, Craft S, Gandy S, Buettner C, Stoeckel LE, Holtzman DM, Nathan DM.

Nat Rev Neurol. 2018 Mar;14(3):168-181. doi: 10.1038/nrneurol.2017.185. Epub 2018 Jan 29. Review.

27.

CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer's PSEN2 N141I neurons.

Ortiz-Virumbrales M, Moreno CL, Kruglikov I, Marazuela P, Sproul A, Jacob S, Zimmer M, Paull D, Zhang B, Schadt EE, Ehrlich ME, Tanzi RE, Arancio O, Noggle S, Gandy S.

Acta Neuropathol Commun. 2017 Oct 27;5(1):77. doi: 10.1186/s40478-017-0475-z.

28.

Military Blast Injury and Chronic Neurodegeneration: Research Presentations from the 2015 International State-of-the-Science Meeting.

Agoston D, Arun P, Bellgowan P, Broglio S, Cantu R, Cook D, da Silva UO, Dickstein D, Elder G, Fudge E, Gandy S, Gill J, Glenn JF, Gupta RK, Hinds S, Hoffman S, Lattimore T, Lin A, Lu KP, Maroon J, Okonkwo D, Perl D, Robinson M, Rosen C, Smith D.

J Neurotrauma. 2017 Sep;34(S1):S6-S17. doi: 10.1089/neu.2017.5220.

29.

Imaging in Vascular Access.

Murphy EA, Ross RA, Jones RG, Gandy SJ, Aristokleous N, Salsano M, Weir-McCall JR, Matthew S, Houston JG.

Cardiovasc Eng Technol. 2017 Sep;8(3):255-272. doi: 10.1007/s13239-017-0317-y. Epub 2017 Jul 13. Review.

30.

Multiple Mechanisms Linking Type 2 Diabetes and Alzheimer's Disease: Testosterone as a Modifier.

Asih PR, Tegg ML, Sohrabi H, Carruthers M, Gandy SE, Saad F, Verdile G, Ittner LM, Martins RN.

J Alzheimers Dis. 2017;59(2):445-466. doi: 10.3233/JAD-161259. Review.

31.

Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer's pathology.

Haure-Mirande JV, Audrain M, Fanutza T, Kim SH, Klein WL, Glabe C, Readhead B, Dudley JT, Blitzer RD, Wang M, Zhang B, Schadt EE, Gandy S, Ehrlich ME.

Acta Neuropathol. 2017 Nov;134(5):769-788. doi: 10.1007/s00401-017-1737-3. Epub 2017 Jun 13.

32.

Directed Differentiation of Human Pluripotent Stem Cells to Microglia.

Douvaras P, Sun B, Wang M, Kruglikov I, Lallos G, Zimmer M, Terrenoire C, Zhang B, Gandy S, Schadt E, Freytes DO, Noggle S, Fossati V.

Stem Cell Reports. 2017 Jun 6;8(6):1516-1524. doi: 10.1016/j.stemcr.2017.04.023. Epub 2017 May 18.

33.

Reply: The Enigma of Left Ventricular Non-Compaction.

Weir-McCall JR, Yeap PM, Papagiorcopulo C, Fitzgerald K, Gandy SJ, Lambert M, Belch JJF, Cavin I, Littleford R, Macfarlane JA, Matthew SZ, Nicholas RS, Struthers AD, Sullivan F, Henderson SA, White RD, Houston JG.

J Am Coll Cardiol. 2017 May 16;69(19):2470-2471. doi: 10.1016/j.jacc.2017.02.062. No abstract available.

34.

Midlife interventions are critical in prevention, delay, or improvement of Alzheimer's disease and vascular cognitive impairment and dementia.

Gandy S, Bartfai T, Lees GV, Sano M.

F1000Res. 2017 Apr 3;6:413. doi: 10.12688/f1000research.11140.1. eCollection 2017.

35.

Effects of inaccuracies in arterial path length measurement on differences in MRI and tonometry measured pulse wave velocity.

Weir-McCall JR, Khan F, Cassidy DB, Thakur A, Summersgill J, Matthew SZ, Adams F, Dove F, Gandy SJ, Colhoun HM, Belch JJ, Houston JG.

BMC Cardiovasc Disord. 2017 May 10;17(1):118. doi: 10.1186/s12872-017-0546-x.

36.

The factor structure of the Mystical Experience Questionnaire (MEQ): Reply to Barrett & Griffiths (2016).

Bouso JC, Pedrero-Pérez EJ, Gandy S, Alcázar-Córcoles MÁ.

Hum Psychopharmacol. 2017 Jan;32(1). doi: 10.1002/hup.2570. No abstract available.

PMID:
28120484
37.

Antemortem biomarker support for a diagnosis of clinically probable chronic traumatic encephalopathy.

Pullman MY, Dickstein DL, DeKosky ST, Gandy S.

Mol Psychiatry. 2017 May;22(5):638-639. doi: 10.1038/mp.2016.236. Epub 2017 Jan 10. No abstract available.

38.

Left Ventricular Noncompaction: Anatomical Phenotype or Distinct Cardiomyopathy?

Weir-McCall JR, Yeap PM, Papagiorcopulo C, Fitzgerald K, Gandy SJ, Lambert M, Belch JJ, Cavin I, Littleford R, Macfarlane JA, Matthew SZ, Nicholas RS, Struthers AD, Sullivan F, Waugh SA, White RD, Houston JG.

J Am Coll Cardiol. 2016 Nov 15;68(20):2157-2165. doi: 10.1016/j.jacc.2016.08.054.

39.

Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer's disease.

Wang M, Roussos P, McKenzie A, Zhou X, Kajiwara Y, Brennand KJ, De Luca GC, Crary JF, Casaccia P, Buxbaum JD, Ehrlich M, Gandy S, Goate A, Katsel P, Schadt E, Haroutunian V, Zhang B.

Genome Med. 2016 Nov 1;8(1):104.

40.

Lysosomal dysfunction in the brain of a mouse model with intraneuronal accumulation of carboxyl terminal fragments of the amyloid precursor protein.

Kaur G, Pawlik M, Gandy SE, Ehrlich ME, Smiley JF, Levy E.

Mol Psychiatry. 2017 Jul;22(7):981-989. doi: 10.1038/mp.2016.189. Epub 2016 Oct 25.

41.

Cerebral [18 F]T807/AV1451 retention pattern in clinically probable CTE resembles pathognomonic distribution of CTE tauopathy.

Dickstein DL, Pullman MY, Fernandez C, Short JA, Kostakoglu L, Knesaurek K, Soleimani L, Jordan BD, Gordon WA, Dams-O'Connor K, Delman BN, Wong E, Tang CY, DeKosky ST, Stone JR, Cantu RC, Sano M, Hof PR, Gandy S.

Transl Psychiatry. 2016 Sep 27;6(9):e900. doi: 10.1038/tp.2016.175.

42.

Prevalence of unrecognized myocardial infarction in a low-intermediate risk asymptomatic cohort and its relation to systemic atherosclerosis.

Weir-McCall JR, Fitzgerald K, Papagiorcopulo CJ, Gandy SJ, Lambert M, Belch JJF, Cavin I, Littleford R, Macfarlane JA, Matthew SZ, Nicholas RS, Struthers AD, Sullivan FM, Waugh SA, White RD, Houston JG.

Eur Heart J Cardiovasc Imaging. 2017 Jun 1;18(6):657-662. doi: 10.1093/ehjci/jew155.

43.

Measuring the subjective: revisiting the psychometric properties of three rating scales that assess the acute effects of hallucinogens.

Bouso JC, Pedrero-Pérez EJ, Gandy S, Alcázar-Córcoles MÁ.

Hum Psychopharmacol. 2016 Sep;31(5):356-72. doi: 10.1002/hup.2545. Epub 2016 Jul 29.

PMID:
27470427
44.

Whole-body cardiovascular MRI for the comparison of atherosclerotic burden and cardiac remodelling in healthy South Asian and European adults.

Weir-McCall JR, Cassidy DB, Belch JJ, Gandy SJ, Houston JG, Lambert MA, Littleford RC, Rowland J, Struthers AD, Khan F.

Br J Radiol. 2016 Sep;89(1065):20160342. doi: 10.1259/bjr.20160342. Epub 2016 Jun 28.

45.

Complex mechanisms linking neurocognitive dysfunction to insulin resistance and other metabolic dysfunction.

Stoeckel LE, Arvanitakis Z, Gandy S, Small D, Kahn CR, Pascual-Leone A, Pawlyk A, Sherwin R, Smith P.

Version 2. F1000Res. 2016 Mar 15 [revised 2016 Jan 1];5:353. doi: 10.12688/f1000research.8300.2. eCollection 2016. Review.

46.

Effective anti-Alzheimer Aβ therapy involves depletion of specific Aβ oligomer subtypes.

Knight EM, Kim SH, Kottwitz JC, Hatami A, Albay R, Suzuki A, Lublin A, Alberini CM, Klein WL, Szabo P, Relkin NR, Ehrlich M, Glabe CG, Gandy S, Steele JW.

Neurol Neuroimmunol Neuroinflamm. 2016 May 10;3(3):e237. doi: 10.1212/NXI.0000000000000237. eCollection 2016 Jun.

47.

3T MRI investigation of cardiac left ventricular structure and function in a UK population: The tayside screening for the prevention of cardiac events (TASCFORCE) study.

Gandy SJ, Lambert M, Belch J, Cavin I, Crowe E, Littleford R, MacFarlane JA, Matthew SZ, Martin P, Nicholas RS, Struthers A, Sullivan F, Waugh SA, White RD, Weir-McCall JR, Houston JG.

J Magn Reson Imaging. 2016 Nov;44(5):1186-1196. doi: 10.1002/jmri.25267. Epub 2016 May 3.

48.

Serum high-density lipoprotein is associated with better cognitive function in a cross-sectional study of aging women.

Bates KA, Sohrabi HR, Rainey-Smith SR, Weinborn M, Bucks RS, Rodrigues M, Beilby J, Howard M, Taddei K, Martins G, Paton A, Shah T, Dhaliwal SS, Foster JK, Martins IJ, Lautenschlager NT, Mastaglia FL, Gandy SE, Martins RN.

Int J Neurosci. 2017 Mar;127(3):243-252. doi: 10.1080/00207454.2016.1182527. Epub 2016 May 15.

PMID:
27113638
49.

Sex differences in cognition: Does the "fairer sex" need a fairer test?

Sano M, Gandy S.

Neurology. 2016 Apr 12;86(15):1364-1365. doi: 10.1212/WNL.0000000000002573. Epub 2016 Mar 16. No abstract available.

PMID:
26984948
50.

Increased susceptibility to metabolic dysregulation in a mouse model of Alzheimer's disease is associated with impaired hypothalamic insulin signaling and elevated BCAA levels.

Ruiz HH, Chi T, Shin AC, Lindtner C, Hsieh W, Ehrlich M, Gandy S, Buettner C.

Alzheimers Dement. 2016 Aug;12(8):851-61. doi: 10.1016/j.jalz.2016.01.008. Epub 2016 Feb 28.

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