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Items: 1 to 50 of 529

1.

Surface-Modified Shortwave-Infrared-Emitting Nanophotonic Reporters for Gene-Therapy Applications.

Zhao Z, Kantamneni H, He S, Pelka S, Venkataraman AS, Kwon M, Libutti SK, Pierce M, Moghe PV, Ganapathy V, Tan MC.

ACS Biomater Sci Eng. 2018 Jul 9;4(7):2305-2363. doi: 10.1021/acsbiomaterials.8b00378. Epub 2018 Apr 30.

2.

Embryonic lethality in mice due to carnitine transporter OCTN2 defect and placental carnitine deficiency.

Shekhawat PS, Sonne S, Matern D, Ganapathy V.

Placenta. 2018 Sep;69:71-73. doi: 10.1016/j.placenta.2018.06.312. Epub 2018 Jun 30.

PMID:
30213487
3.

Antibiotic use in patients hospitalized with chronic obstructive pulmonary disease.

Dietrich E, Davis K, Amin AN, Ganapathy V, Netzer L.

Am J Health Syst Pharm. 2018 Sep 1;75(17):1268-1269. doi: 10.2146/ajhp180178. No abstract available.

PMID:
30139734
4.

Chemical validation and optimization of pharmacoperones targeting vasopressin type 2 receptor mutant.

Janovick JA, Spicer TP, Bannister TD, Smith E, Ganapathy V, Scampavia L.

Biochem J. 2018 Sep 25;475(18):2941-2953. doi: 10.1042/BCJ20180065.

PMID:
30068530
5.

Retraction Note: Identification of a novel Na+-coupled Fe3+-citrate transport system, distinct from mammalian INDY, for uptake of citrate in mammalian cells.

Ogura J, Babu E, Miyauchi S, Ramachandran S, Nemeth E, Bhutia YD, Ganapathy V.

Sci Rep. 2018 Jul 17;8(1):11021. doi: 10.1038/s41598-018-28645-x.

6.

Recent advances in drug delivery via the organic cation/carnitine transporter 2 (OCTN2/SLC22A5).

Kou L, Sun R, Ganapathy V, Yao Q, Chen R.

Expert Opin Ther Targets. 2018 Aug;22(8):715-726. doi: 10.1080/14728222.2018.1502273. Epub 2018 Jul 23.

PMID:
30016594
7.

Preparation of self-assembled platinum nanoclusters to combat Salmonella typhi infection and inhibit biofilm formation.

Subramaniyan SB, Ramani A, Ganapathy V, Anbazhagan V.

Colloids Surf B Biointerfaces. 2018 Nov 1;171:75-84. doi: 10.1016/j.colsurfb.2018.07.023. Epub 2018 Jul 11.

PMID:
30015141
8.

Fronto-striatal effective connectivity of working memory in adults with cannabis use disorder.

Ma L, Steinberg JL, Bjork JM, Keyser-Marcus L, Vassileva J, Zhu M, Ganapathy V, Wang Q, Boone EL, Ferré S, Bickel WK, Gerard Moeller F.

Psychiatry Res Neuroimaging. 2018 Jun 8;278:21-34. doi: 10.1016/j.pscychresns.2018.05.010. [Epub ahead of print]

PMID:
29957349
9.

Electronic cigarette aerosols induce DNA damage and reduce DNA repair: Consistency across species.

Queimado L, Wagener T, Ganapathy V.

Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):E5437-E5438. doi: 10.1073/pnas.1807411115. Epub 2018 May 25. No abstract available.

PMID:
29802233
10.

Multiscale optical imaging of rare-earth-doped nanocomposites in a small animal model.

Higgins LM, Ganapathy V, Kantamneni H, Zhao X, Sheng Y, Tan MC, Roth CM, Riman RE, Moghe PV, Pierce MC.

J Biomed Opt. 2018 Mar;23(3):1-4. doi: 10.1117/1.JBO.23.3.030505.

PMID:
29564865
11.

Treatment patterns for patients hospitalized with chronic obstructive pulmonary disease.

Amin AN, Bollu V, Stensland MD, Netzer L, Ganapathy V.

Am J Health Syst Pharm. 2018 Mar 15;75(6):359-366. doi: 10.2146/ajhp160979.

PMID:
29523532
12.

Gpr109a Limits Microbiota-Induced IL-23 Production To Constrain ILC3-Mediated Colonic Inflammation.

Bhatt B, Zeng P, Zhu H, Sivaprakasam S, Li S, Xiao H, Dong L, Shiao P, Kolhe R, Patel N, Li H, Levy-Bercowski D, Ganapathy V, Singh N.

J Immunol. 2018 Apr 15;200(8):2905-2914. doi: 10.4049/jimmunol.1701625. Epub 2018 Mar 7.

PMID:
29514953
13.

Extracellular Citrate Affects Critical Elements of Cancer Cell Metabolism and Supports Cancer Development In Vivo.

Mycielska ME, Dettmer K, Rümmele P, Schmidt K, Prehn C, Milenkovic VM, Jagla W, Madej GM, Lantow M, Schladt M, Cecil A, Koehl GE, Eggenhofer E, Wachsmuth CJ, Ganapathy V, Schlitt HJ, Kunzelmann K, Ziegler C, Wetzel CH, Gaumann A, Lang SA, Adamski J, Oefner PJ, Geissler EK.

Cancer Res. 2018 May 15;78(10):2513-2523. doi: 10.1158/0008-5472.CAN-17-2959. Epub 2018 Mar 6.

PMID:
29510993
14.

Vesicle-based secretion in schistosomes: Analysis of protein and microRNA (miRNA) content of exosome-like vesicles derived from Schistosoma mansoni.

Samoil V, Dagenais M, Ganapathy V, Aldridge J, Glebov A, Jardim A, Ribeiro P.

Sci Rep. 2018 Feb 19;8(1):3286. doi: 10.1038/s41598-018-21587-4.

15.

Iron Overload Accelerates the Progression of Diabetic Retinopathy in Association with Increased Retinal Renin Expression.

Chaudhary K, Promsote W, Ananth S, Veeranan-Karmegam R, Tawfik A, Arjunan P, Martin P, Smith SB, Thangaraju M, Kisselev O, Ganapathy V, Gnana-Prakasam JP.

Sci Rep. 2018 Feb 14;8(1):3025. doi: 10.1038/s41598-018-21276-2.

16.

Transporter-Guided Delivery of Nanoparticles to Improve Drug Permeation across Cellular Barriers and Drug Exposure to Selective Cell Types.

Kou L, Bhutia YD, Yao Q, He Z, Sun J, Ganapathy V.

Front Pharmacol. 2018 Jan 26;9:27. doi: 10.3389/fphar.2018.00027. eCollection 2018. Review.

17.

Identification of a novel Na+-coupled Fe3+-citrate transport system, distinct from mammalian INDY, for uptake of citrate in mammalian cells.

Ogura J, Babu E, Miyauchi S, Ramachandran S, Nemeth E, Bhutia YD, Ganapathy V.

Sci Rep. 2018 Feb 6;8(1):2519. doi: 10.1038/s41598-018-20620-w. Retraction in: Sci Rep. 2018 Jul 17;8(1):11021.

18.

GPR81, a Cell-Surface Receptor for Lactate, Regulates Intestinal Homeostasis and Protects Mice from Experimental Colitis.

Ranganathan P, Shanmugam A, Swafford D, Suryawanshi A, Bhattacharjee P, Hussein MS, Koni PA, Prasad PD, Kurago ZB, Thangaraju M, Ganapathy V, Manicassamy S.

J Immunol. 2018 Mar 1;200(5):1781-1789. doi: 10.4049/jimmunol.1700604. Epub 2018 Jan 31.

PMID:
29386257
19.

Short-Chain Fatty Acid Transporters: Role in Colonic Homeostasis.

Sivaprakasam S, Bhutia YD, Yang S, Ganapathy V.

Compr Physiol. 2017 Dec 12;8(1):299-314. doi: 10.1002/cphy.c170014.

20.

Delay in State Adoption of Newborn Screening Tests.

Xu A, Ganapathy V, Morain SR.

Pediatrics. 2018 Jan;141(1). pii: e20170300. doi: 10.1542/peds.2017-0300. Epub 2017 Dec 20. No abstract available. Erratum in: Pediatrics. 2018 Mar 30;:.

PMID:
29263252
21.

The Na+/Cl--Coupled, Broad-Specific, Amino Acid Transporter SLC6A14 (ATB0,+): Emerging Roles in Multiple Diseases and Therapeutic Potential for Treatment and Diagnosis.

Sikder MOF, Yang S, Ganapathy V, Bhutia YD.

AAPS J. 2017 Dec 4;20(1):12. doi: 10.1208/s12248-017-0164-7. Review.

PMID:
29204754
22.

Role of estrogen receptor beta in neural differentiation of mouse embryonic stem cells.

Varshney MK, Inzunza J, Lupu D, Ganapathy V, Antonson P, Rüegg J, Nalvarte I, Gustafsson JÅ.

Proc Natl Acad Sci U S A. 2017 Nov 28;114(48):E10428-E10437. doi: 10.1073/pnas.1714094114. Epub 2017 Nov 13.

23.

Effective Floquet Hamiltonian theory of multiple-quantum NMR in anisotropic solids involving quadrupolar spins: Challenges and Perspectives.

Ganapathy V, Ramachandran R.

J Chem Phys. 2017 Oct 14;147(14):144202. doi: 10.1063/1.4993313.

PMID:
29031275
24.

L-Carnitine-conjugated nanoparticles to promote permeation across blood-brain barrier and to target glioma cells for drug delivery via the novel organic cation/carnitine transporter OCTN2.

Kou L, Hou Y, Yao Q, Guo W, Wang G, Wang M, Fu Q, He Z, Ganapathy V, Sun J.

Artif Cells Nanomed Biotechnol. 2018 Dec;46(8):1605-1616. doi: 10.1080/21691401.2017.1384385. Epub 2017 Oct 3.

PMID:
28974108
25.

Hydroxyurea differentially modulates activator and repressors of γ-globin gene in erythroblasts of responsive and non-responsive patients with sickle cell disease in correlation with Index of Hydroxyurea Responsiveness.

Zhu X, Hu T, Ho MH, Wang Y, Yu M, Patel N, Pi W, Choi JH, Xu H, Ganapathy V, Kutlar F, Kutlar A, Tuan D.

Haematologica. 2017 Dec;102(12):1995-2004. doi: 10.3324/haematol.2017.175646. Epub 2017 Sep 29.

26.

Carbidopa is an activator of aryl hydrocarbon receptor with potential for cancer therapy.

Ogura J, Miyauchi S, Shimono K, Yang S, Gonchigar S, Ganapathy V, Bhutia YD.

Biochem J. 2017 Sep 28;474(20):3391-3402. doi: 10.1042/BCJ20170583.

PMID:
28963435
27.

Dual targeting of l-carnitine-conjugated nanoparticles to OCTN2 and ATB0,+ to deliver chemotherapeutic agents for colon cancer therapy.

Kou L, Yao Q, Sivaprakasam S, Luo Q, Sun Y, Fu Q, He Z, Sun J, Ganapathy V.

Drug Deliv. 2017 Nov;24(1):1338-1349. doi: 10.1080/10717544.2017.1377316.

PMID:
28911246
28.

Prevalence of Low Peak Inspiratory Flow Rate at Discharge in Patients Hospitalized for COPD Exacerbation.

Sharma G, Mahler DA, Mayorga VM, Deering KL, Harshaw O, Ganapathy V.

Chronic Obstr Pulm Dis. 2017 Jul 15;4(3):217-224. doi: 10.15326/jcopdf.4.3.2017.0183.

29.

Monomethyl fumarate inhibits pain behaviors and amygdala activity in a rat arthritis model.

Kim H, Thompson J, Ji G, Ganapathy V, Neugebauer V.

Pain. 2017 Dec;158(12):2376-2385. doi: 10.1097/j.pain.0000000000001042.

PMID:
28832396
30.

Cell-Surface and Nuclear Receptors in the Colon as Targets for Bacterial Metabolites and Its Relevance to Colon Health.

Sivaprakasam S, Bhutia YD, Ramachandran S, Ganapathy V.

Nutrients. 2017 Aug 10;9(8). pii: E856. doi: 10.3390/nu9080856. Review.

31.

Confidence in correct inhaler technique and its association with treatment adherence and health status among US patients with chronic obstructive pulmonary disease.

Amin AN, Ganapathy V, Roughley A, Small M.

Patient Prefer Adherence. 2017 Jul 12;11:1205-1212. doi: 10.2147/PPA.S140139. eCollection 2017.

32.

Health resource utilization for inpatients with COPD treated with nebulized arformoterol or nebulized formoterol.

Ganapathy V, Stensland MD.

Int J Chron Obstruct Pulmon Dis. 2017 Jun 20;12:1793-1801. doi: 10.2147/COPD.S134145. eCollection 2017.

33.

Cotransporting Ion is a Trigger for Cellular Endocytosis of Transporter-Targeting Nanoparticles: A Case Study of High-Efficiency SLC22A5 (OCTN2)-Mediated Carnitine-Conjugated Nanoparticles for Oral Delivery of Therapeutic Drugs.

Kou L, Yao Q, Sun M, Wu C, Wang J, Luo Q, Wang G, Du Y, Fu Q, Wang J, He Z, Ganapathy V, Sun J.

Adv Healthc Mater. 2017 Sep;6(17). doi: 10.1002/adhm.201700165. Epub 2017 Jun 29.

PMID:
28661032
34.

Electronic cigarette aerosols suppress cellular antioxidant defenses and induce significant oxidative DNA damage.

Ganapathy V, Manyanga J, Brame L, McGuire D, Sadhasivam B, Floyd E, Rubenstein DA, Ramachandran I, Wagener T, Queimado L.

PLoS One. 2017 May 18;12(5):e0177780. doi: 10.1371/journal.pone.0177780. eCollection 2017.

35.

Cell-surface G-protein-coupled receptors for tumor-associated metabolites: A direct link to mitochondrial dysfunction in cancer.

Ristic B, Bhutia YD, Ganapathy V.

Biochim Biophys Acta Rev Cancer. 2017 Aug;1868(1):246-257. doi: 10.1016/j.bbcan.2017.05.003. Epub 2017 May 13. Review.

36.

Gut Microbiome and Colon Cancer: Role of Bacterial Metabolites and Their Molecular Targets in the Host.

Bhutia YD, Ogura J, Sivaprakasam S, Ganapathy V.

Curr Colorectal Cancer Rep. 2017 Apr;13(2):111-118. doi: 10.1007/s11888-017-0362-9. Epub 2017 Feb 22.

37.

Plasma Membrane Na⁺-Coupled Citrate Transporter (SLC13A5) and Neonatal Epileptic Encephalopathy.

Bhutia YD, Kopel JJ, Lawrence JJ, Neugebauer V, Ganapathy V.

Molecules. 2017 Feb 28;22(3). pii: E378. doi: 10.3390/molecules22030378. Review.

38.

Influence of postoperative sagittal balance and spinopelvic parameters on the outcome of patients surgically treated for degenerative lumbar spondylolisthesis.

Radovanovic I, Urquhart JC, Ganapathy V, Siddiqi F, Gurr KR, Bailey SI, Bailey CS.

J Neurosurg Spine. 2017 Apr;26(4):448-453. doi: 10.3171/2016.9.SPINE1680. Epub 2017 Jan 20.

PMID:
28106523
39.

Cystic Pheochromocytoma Presenting as Adrenal Cyst.

Abdulsalam MS, Ganapathy V, Satish P, Janakiraman RK, Singh S.

J Clin Diagn Res. 2016 Nov;10(11):OD09-OD10. doi: 10.7860/JCDR/2016/20129.8892. Epub 2016 Nov 1.

40.

Yoga: Past and Present.

Pandurangi AK, Keshavan MS, Ganapathy V, Gangadhar BN.

Am J Psychiatry. 2017 Jan 1;174(1):16-17. doi: 10.1176/appi.ajp.2016.16080853. No abstract available.

PMID:
28040996
41.

Surveillance nanotechnology for multi-organ cancer metastases.

Kantamneni H, Zevon M, Donzanti MJ, Zhao X, Sheng Y, Barkund SR, McCabe LH, Banach-Petrosky W, Higgins LM, Ganesan S, Riman RE, Roth CM, Tan MC, Pierce MC, Ganapathy V, Moghe PV.

Nat Biomed Eng. 2017;1:993-1003. doi: 10.1038/s41551-017-0167-9. Epub 2017 Dec 12.

42.

Health Status of Patients with Moderate to Severe COPD after Treatment with Nebulized Arformoterol Tartrate or Placebo for 1 Year.

Donohue JF, Ganapathy V, Bollu V, Stensland MD, Nelson LM.

Clin Ther. 2017 Jan;39(1):66-74. doi: 10.1016/j.clinthera.2016.11.021. Epub 2016 Dec 20.

PMID:
28011247
43.

Transporter occluded-state conformation-induced endocytosis: Amino acid transporter ATB0,+-mediated tumor targeting of liposomes for docetaxel delivery for hepatocarcinoma therapy.

Luo Q, Gong P, Sun M, Kou L, Ganapathy V, Jing Y, He Z, Sun J.

J Control Release. 2016 Dec 10;243:370-380. doi: 10.1016/j.jconrel.2016.10.031. Epub 2016 Nov 1.

PMID:
27810556
44.

Nutrient Transporter Expression in the Jejunum in Relation to Body Mass Index in Patients Undergoing Bariatric Surgery.

Irving BA, Wood GC, Bennotti PN, Babu E, Deshpande A, Lent MR, Petrick A, Gabrielsen J, Strodel W, Gerhard GS, Still CD, Ganapathy V, Rolston DD.

Nutrients. 2016 Oct 29;8(11). pii: E683.

45.

High fructose-mediated attenuation of insulin receptor signaling does not affect PDGF-induced proliferative signaling in vascular smooth muscle cells.

Osman I, Poulose N, Ganapathy V, Segar L.

Eur J Pharmacol. 2016 Nov 15;791:703-710. doi: 10.1016/j.ejphar.2016.10.007. Epub 2016 Oct 8.

46.

Amino acid transporter SLC6A14 is a novel and effective drug target for pancreatic cancer.

Coothankandaswamy V, Cao S, Xu Y, Prasad PD, Singh PK, Reynolds CP, Yang S, Ogura J, Ganapathy V, Bhutia YD.

Br J Pharmacol. 2016 Dec;173(23):3292-3306. doi: 10.1111/bph.13616. Epub 2016 Oct 18.

47.

Oral Monomethyl Fumarate Therapy Ameliorates Retinopathy in a Humanized Mouse Model of Sickle Cell Disease.

Promsote W, Powell FL, Veean S, Thounaojam M, Markand S, Saul A, Gutsaeva D, Bartoli M, Smith SB, Ganapathy V, Martin PM.

Antioxid Redox Signal. 2016 Dec 10;25(17):921-935. Epub 2016 Aug 22.

48.

An essential role of Ffar2 (Gpr43) in dietary fibre-mediated promotion of healthy composition of gut microbiota and suppression of intestinal carcinogenesis.

Sivaprakasam S, Gurav A, Paschall AV, Coe GL, Chaudhary K, Cai Y, Kolhe R, Martin P, Browning D, Huang L, Shi H, Sifuentes H, Vijay-Kumar M, Thompson SA, Munn DH, Mellor A, McGaha TL, Shiao P, Cutler CW, Liu K, Ganapathy V, Li H, Singh N.

Oncogenesis. 2016 Jun 27;5(6):e238. doi: 10.1038/oncsis.2016.38.

49.

Re-programming tumour cell metabolism to treat cancer: no lone target for lonidamine.

Bhutia YD, Babu E, Ganapathy V.

Biochem J. 2016 Jun 1;473(11):1503-6. doi: 10.1042/BCJ20160068. Review.

50.

Combined Inhibition of DNMT and HDAC Blocks the Tumorigenicity of Cancer Stem-like Cells and Attenuates Mammary Tumor Growth.

Pathania R, Ramachandran S, Mariappan G, Thakur P, Shi H, Choi JH, Manicassamy S, Kolhe R, Prasad PD, Sharma S, Lokeshwar BL, Ganapathy V, Thangaraju M.

Cancer Res. 2016 Jun 1;76(11):3224-35. doi: 10.1158/0008-5472.CAN-15-2249. Epub 2016 Apr 5.

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