Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 50

1.

Sphingolipid Modulation Activates Proteostasis Programs to Govern Human Hematopoietic Stem Cell Self-Renewal.

Xie SZ, Garcia-Prat L, Voisin V, Ferrari R, Gan OI, Wagenblast E, Kaufmann KB, Zeng AGX, Takayanagi SI, Patel I, Lee EK, Jargstorf J, Holmes G, Romm G, Pan K, Shoong M, Vedi A, Luberto C, Minden MD, Bader GD, Laurenti E, Dick JE.

Cell Stem Cell. 2019 Oct 11. pii: S1934-5909(19)30393-5. doi: 10.1016/j.stem.2019.09.008. [Epub ahead of print]

2.

Functional profiling of single CRISPR/Cas9-edited human long-term hematopoietic stem cells.

Wagenblast E, Azkanaz M, Smith SA, Shakib L, McLeod JL, Krivdova G, Araújo J, Shultz LD, Gan OI, Dick JE, Lechman ER.

Nat Commun. 2019 Oct 18;10(1):4730. doi: 10.1038/s41467-019-12726-0.

PMID:
31628330
3.

An ERG Enhancer-Based Reporter Identifies Leukemia Cells with Elevated Leukemogenic Potential Driven by ERG-USP9X Feed-Forward Regulation.

Aqaqe N, Yassin M, Yassin AA, Ershaid N, Katz-Even C, Zipin-Roitman A, Kugler E, Lechman ER, Gan OI, Mitchell A, Dick JE, Izraeli S, Milyavsky M.

Cancer Res. 2019 Aug 1;79(15):3862-3876. doi: 10.1158/0008-5472.CAN-18-3215. Epub 2019 Jun 7.

PMID:
31175119
4.

SMYD2 lysine methyltransferase regulates leukemia cell growth and regeneration after genotoxic stress.

Zipin-Roitman A, Aqaqe N, Yassin M, Biechonski S, Amar M, van Delft MF, Gan OI, McDermott SP, Buzina A, Ketela T, Shlush L, Xie S, Voisin V, Moffat J, Minden MD, Dick JE, Milyavsky M.

Oncotarget. 2017 Mar 7;8(10):16712-16727. doi: 10.18632/oncotarget.15147.

5.

Ectopic miR-125a Expression Induces Long-Term Repopulating Stem Cell Capacity in Mouse and Human Hematopoietic Progenitors.

Wojtowicz EE, Lechman ER, Hermans KG, Schoof EM, Wienholds E, Isserlin R, van Veelen PA, Broekhuis MJ, Janssen GM, Trotman-Grant A, Dobson SM, Krivdova G, Elzinga J, Kennedy J, Gan OI, Sinha A, Ignatchenko V, Kislinger T, Dethmers-Ausema B, Weersing E, Alemdehy MF, de Looper HW, Bader GD, Ritsema M, Erkeland SJ, Bystrykh LV, Dick JE, de Haan G.

Cell Stem Cell. 2016 Sep 1;19(3):383-96. doi: 10.1016/j.stem.2016.06.008. Epub 2016 Jul 14.

6.

Distinct routes of lineage development reshape the human blood hierarchy across ontogeny.

Notta F, Zandi S, Takayama N, Dobson S, Gan OI, Wilson G, Kaufmann KB, McLeod J, Laurenti E, Dunant CF, McPherson JD, Stein LD, Dror Y, Dick JE.

Science. 2016 Jan 8;351(6269):aab2116. doi: 10.1126/science.aab2116. Epub 2015 Nov 5.

7.

Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer.

Kreso A, O'Brien CA, van Galen P, Gan OI, Notta F, Brown AM, Ng K, Ma J, Wienholds E, Dunant C, Pollett A, Gallinger S, McPherson J, Mullighan CG, Shibata D, Dick JE.

Science. 2013 Feb 1;339(6119):543-8. doi: 10.1126/science.1227670. Epub 2012 Dec 13.

8.

A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis-independent role for p53 in self-renewal.

Milyavsky M, Gan OI, Trottier M, Komosa M, Tabach O, Notta F, Lechman E, Hermans KG, Eppert K, Konovalova Z, Ornatsky O, Domany E, Meyn MS, Dick JE.

Cell Stem Cell. 2010 Aug 6;7(2):186-97. doi: 10.1016/j.stem.2010.05.016. Epub 2010 Jul 8.

9.

Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells.

Takenaka K, Prasolava TK, Wang JC, Mortin-Toth SM, Khalouei S, Gan OI, Dick JE, Danska JS.

Nat Immunol. 2007 Dec;8(12):1313-23. Epub 2007 Nov 4.

PMID:
17982459
10.

Reversible cell surface expression of CD38 on CD34-positive human hematopoietic repopulating cells.

McKenzie JL, Gan OI, Doedens M, Dick JE.

Exp Hematol. 2007 Sep;35(9):1429-36. Epub 2007 Jul 25.

PMID:
17656009
11.

Individual stem cells with highly variable proliferation and self-renewal properties comprise the human hematopoietic stem cell compartment.

McKenzie JL, Gan OI, Doedens M, Wang JC, Dick JE.

Nat Immunol. 2006 Nov;7(11):1225-33. Epub 2006 Oct 1.

PMID:
17013390
12.

Low rhodamine 123 retention identifies long-term human hematopoietic stem cells within the Lin-CD34+CD38- population.

McKenzie JL, Takenaka K, Gan OI, Doedens M, Dick JE.

Blood. 2007 Jan 15;109(2):543-5. Epub 2006 Sep 21.

PMID:
16990597
13.
14.

Lentivector-mediated clonal tracking reveals intrinsic heterogeneity in the human hematopoietic stem cell compartment and culture-induced stem cell impairment.

Mazurier F, Gan OI, McKenzie JL, Doedens M, Dick JE.

Blood. 2004 Jan 15;103(2):545-52. Epub 2003 Sep 22.

PMID:
14504079
15.

Characterization of cord blood hematopoietic stem cells.

Mazurier F, Doedens M, Gan OI, Dick JE.

Ann N Y Acad Sci. 2003 May;996:67-71.

PMID:
12799284
16.
18.

In vivo dynamics of human stem cell repopulation in NOD/SCID mice.

Dick JE, Guenechea G, Gan OI, Dorrell C.

Ann N Y Acad Sci. 2001 Jun;938:184-90.

PMID:
11458507
19.

Distinct classes of human stem cells that differ in proliferative and self-renewal potential.

Guenechea G, Gan OI, Dorrell C, Dick JE.

Nat Immunol. 2001 Jan;2(1):75-82.

PMID:
11135582
20.

Transduction of human CD34+ CD38- bone marrow and cord blood-derived SCID-repopulating cells with third-generation lentiviral vectors.

Guenechea G, Gan OI, Inamitsu T, Dorrell C, Pereira DS, Kelly M, Naldini L, Dick JE.

Mol Ther. 2000 Jun;1(6):566-73.

22.
23.

Characterization and retroviral transduction of an early human lymphomyeloid precursor assayed in nonswitched long-term culture on murine stroma.

Gan OI, Dorrell C, Pereira DS, Ito CY, Wang JC, Dick JE.

Exp Hematol. 1999 Jun;27(6):1097-106.

PMID:
10378899
24.

A newly discovered class of human hematopoietic cells with SCID-repopulating activity.

Bhatia M, Bonnet D, Murdoch B, Gan OI, Dick JE.

Nat Med. 1998 Sep;4(9):1038-45.

PMID:
9734397
25.

Retroviral transduction of TLS-ERG initiates a leukemogenic program in normal human hematopoietic cells.

Pereira DS, Dorrell C, Ito CY, Gan OI, Murdoch B, Rao VN, Zou JP, Reddy ES, Dick JE.

Proc Natl Acad Sci U S A. 1998 Jul 7;95(14):8239-44.

26.

Bone marrow failure in the Fanconi anemia group C mouse model after DNA damage.

Carreau M, Gan OI, Liu L, Doedens M, McKerlie C, Dick JE, Buchwald M.

Blood. 1998 Apr 15;91(8):2737-44.

PMID:
9531583
28.

[The effect of leukemia-inhibitory factor on the hematopoiesis and stromal precursor cells in long-term culture of murine bone marrow].

Drize NI, Gan OI, Chertkov IL, Goddar A, Jaques J.

Biull Eksp Biol Med. 1996 Sep;122(9):325-8. Russian. No abstract available.

PMID:
8974492
29.

TPSg, an anti-human immunodeficiency virus (HIV-1) agent, isolated from the Cupressaceae Thuja occidentale L. (Arborvitae) enhances in vivo hemopoietic progenitor cells recovery in sublethally irradiated mice.

Hassan HT, Drize NJ, Sadovinkova EYu, Gan OI, Gohla S, Schrum S, Neth RD.

Immunol Lett. 1996 Apr;50(1-2):119-22. No abstract available.

PMID:
8793569
30.
32.

[Hematopoietic stem cells with an introduced foreign gene-- proliferative activity and proliferative potential in the long term period after transplantation in irradiated mice].

Chertkov IL, Drize NI, Gan OI, Olovnikova NI, Belkina EV, Nikolaeva TL.

Biull Eksp Biol Med. 1994 Jun;117(6):648-50. Russian. No abstract available.

PMID:
7915147
34.

[The introduction of the marker gene Neor into hematopoietic stem cells by electroporation].

Drize NI, Gan OI, Surin VL.

Gematol Transfuziol. 1993 Feb;38(2):3-7. Russian.

PMID:
8020717
35.

Gene therapy model for stromal precursor cells of hematopoietic microenvironment.

Drize NJ, Surin VL, Gan OI, Deryugina EI, Chertkov JL.

Leukemia. 1992;6 Suppl 3:174S-175S.

PMID:
1602818
36.

[Effects of polysaccharide from Thuja occidentale L. on stromal precursor cells of hematopoietic microenvironment in mice].

Gan OI, Drize NI, Gola S, Shrum S, Net R.

Biull Eksp Biol Med. 1991 Dec;112(12):635-7. Russian.

PMID:
1777637
37.

[Transduction of a marker gene (Neor) into precursor cells of the hematopoietic microenvironment].

Drize NI, Surin VL, Gan OI, Deriugina EI, Chertkov IL.

Biull Eksp Biol Med. 1991 Nov;112(11):529-32. Russian.

PMID:
1810497
38.

[Hematopoietic stem cells in mice during embryonic development preceding the establishment of liver hematopoiesis].

Gan OI, Medvinskiĭ AL, Samoĭlina NL.

Ontogenez. 1991 Mar-Apr;22(2):133-6. Russian.

PMID:
1857593
39.

[Repair of the radiation damage in hematopoietic stem cells from the mouse embryonic liver. Kinetic aspects].

Gan OI, Todriia TV.

Radiobiologiia. 1991 Mar-Apr;31(2):222-6. Russian.

PMID:
1674612
40.

[Kinetics of reparation of sublethal radiation damage in early hematopoietic precursors].

Todriia TV, Gan OI.

Biull Eksp Biol Med. 1991 Jan;111(1):74-6. Russian.

PMID:
2054482
41.

[The development of the hemopoietic system: colony-forming splenic units in mouse embryogenesis].

Samoĭlina NL, Gan OI, Medvinskiĭ AL.

Ontogenez. 1990 Mar-Apr;21(2):177-84. Russian.

PMID:
2367075
42.

[Induced hematopoietic foci in mice. I. Induction of extraskeletal hematopoietic areas using demineralized tooth matrix].

Gurevich OA, Samoĭlina NL, Medvinskiĭ AL, Gan OI.

Gematol Transfuziol. 1990 Feb;35(2):7-12. Russian.

PMID:
2332137
43.

[Comparative radiosensitivity of CFUs of the mouse bone marrow and embryonal liver forming 7- and 11-day colonies].

Gan OI, Konopliannikov AG.

Biull Eksp Biol Med. 1989 Jan;107(1):93-5. Russian.

PMID:
2914183
44.
45.
46.

[Progenitors of transitory spleen colonies in mouse embryonal liver].

Gan OI, Drize NI, Todriia TV, Chertkov IL.

Biull Eksp Biol Med. 1984 Jun;97(6):727-9. Russian.

PMID:
6743815
47.

[Effect of an inhibitor of granulo- and monocytopoietic precursors on hematopoiesis in an organ culture of embryonic mouse liver].

Samoĭlina NL, Petrova GP, Gan OI.

Gematol Transfuziol. 1984 Apr;29(4):24-8. Russian. No abstract available.

PMID:
6735115
48.

[Effect of colony-stimulating activity on hematopoiesis in the organ culture of mouse embryonal liver].

Gan OI, Samoĭlina NL.

Biull Eksp Biol Med. 1983 Nov;96(11):110-2. Russian.

PMID:
6605769
49.

[Formation of granulocytic-macrophage precursors in organ cultures of the mouse embryo liver].

Gan OI, Samoĭlina NL.

Probl Gematol Pereliv Krovi. 1982 Sep;27(9):46-9. Russian. No abstract available.

PMID:
7178058
50.

[Determination of the granulocyte-macrophage precursors in mouse embryonic liver by the agar diffusion chamber method].

Gan OI.

Probl Gematol Pereliv Krovi. 1981 Jun;26(6):38-42. Russian. No abstract available.

PMID:
7279886

Supplemental Content

Support Center