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Is Myopia associated with the Incidence and Progression of Diabetic Retinopathy?

Man RE, Gan AT, Gupta P, Fenwick EK, Sabanayagam C, Tan NY, Mitchell P, Wong TY, Cheng CY, Lamoureux EL.

Am J Ophthalmol. 2019 May 16. pii: S0002-9394(19)30232-6. doi: 10.1016/j.ajo.2019.05.012. [Epub ahead of print]


Validation of a novel diabetic retinopathy utility index using discrete choice experiments.

Fenwick EK, Bansback N, Gan ATL, Ratcliffe J, Burgess L, Wong TY, Lamoureux EL.

Br J Ophthalmol. 2019 May 16. pii: bjophthalmol-2019-313899. doi: 10.1136/bjophthalmol-2019-313899. [Epub ahead of print]


Association between Choroidal Thickness and Drusen Subtypes in Age-Related Macular Degeneration.

Cheung CMG, Gan A, Yanagi Y, Wong TY, Spaide R.

Ophthalmol Retina. 2018 Dec;2(12):1196-1205. doi: 10.1016/j.oret.2018.06.014. Epub 2018 Aug 29.


Assessing gender trends in Canadian urology.

Stringer L, Morris H, Gan AML, Sener A.

Can Urol Assoc J. 2019 Apr 26. doi: 10.5489/cuaj.5836. [Epub ahead of print]


Six-year incidence and progression of diabetic retinopathy in Indian adults: the Singapore Indian Eye study.

Kumari N, Bhargava M, Nguyen DQ, Gan ATL, Tan G, Cheung N, Tan N, Wong C, Wang JJ, Mitchell P, Lamoureux EL, Cheng CY, Wong TY, Sabanayagam C.

Br J Ophthalmol. 2019 Feb 2. pii: bjophthalmol-2018-313282. doi: 10.1136/bjophthalmol-2018-313282. [Epub ahead of print]


Estimation of bicycle crash modification factors (CMFs) on urban facilities using zero inflated negative binomial models.

Raihan MA, Alluri P, Wu W, Gan A.

Accid Anal Prev. 2019 Feb;123:303-313. doi: 10.1016/j.aap.2018.12.009. Epub 2018 Dec 15.


The Relationship between Generalized and Abdominal Obesity with Diabetic Kidney Disease in Type 2 Diabetes: A Multiethnic Asian Study and Meta-Analysis.

Man REK, Gan ATL, Fenwick EK, Gupta P, Wong MYZ, Wong TY, Tan GSW, Teo BW, Sabanayagam C, Lamoureux EL.

Nutrients. 2018 Nov 5;10(11). pii: E1685. doi: 10.3390/nu10111685.


Beyond vision loss: the independent impact of diabetic retinopathy on vision-related quality of life in a Chinese Singaporean population.

Fenwick EK, Man REK, Gan ATL, Kumari N, Wong C, Aravindhan A, Gupta P, Wang JJ, Mitchell P, Wong TY, Cheng CY, Lamoureux EL.

Br J Ophthalmol. 2018 Oct 25. pii: bjophthalmol-2018-313082. doi: 10.1136/bjophthalmol-2018-313082. [Epub ahead of print]


Risk of Incident Cardiovascular Disease and Cardiovascular Risk Factors in First and Second-Generation Indians: The Singapore Indian Eye Study.

Gupta P, Gan ATL, Man REK, Fenwick EK, Tham YC, Sabanayagam C, Wong TY, Cheng CY, Lamoureux EL.

Sci Rep. 2018 Oct 4;8(1):14805. doi: 10.1038/s41598-018-32833-0.


Cast immobilisation for the treatment of paediatric distal radius fracture: fibreglass versus polyolefin.

Zhu M, Lokino ES, Chan CSH, Gan AJ, Ong LL, Lim KBL.

Singapore Med J. 2019 Apr;60(4):183-187. doi: 10.11622/smedj.2018118. Epub 2018 Sep 24.


Augmented Reality-Assisted Percutaneous Dilatational Tracheostomy in Critically Ill Patients With Chronic Respiratory Disease.

Gan A, Cohen A, Tan L.

J Intensive Care Med. 2019 Feb;34(2):153-155. doi: 10.1177/0885066618791952. Epub 2018 Aug 5.


The impact of DocosaHexaenoic Acid supplementation during pregnancy and lactation on Neurodevelopment of the offspring in India (DHANI): trial protocol.

Khandelwal S, Swamy MK, Patil K, Kondal D, Chaudhry M, Gupta R, Divan G, Kamate M, Ramakrishnan L, Bellad MB, Gan A, Kodkany BS, Martorell R, Srinath Reddy K, Prabhakaran D, Ramakrishnan U, Tandon N, Stein AD.

BMC Pediatr. 2018 Aug 4;18(1):261. doi: 10.1186/s12887-018-1225-5.


Correction to: Cardiospecific deletion of αE-catenin leads to heart failure and lethality in mice.

Balatskyi VV, Macewicz LL, Gan AM, Goncharov SV, Pawelec P, Portnichenko GV, Lapikova-Bryginska TY, Navrulin VO, Dosenko VE, Olichwier A, Dobrzyn P, Piven OO.

Pflugers Arch. 2018 Oct;470(10):1501-1502. doi: 10.1007/s00424-018-2174-4.


Cardiospecific deletion of αE-catenin leads to heart failure and lethality in mice.

Balatskyi VV, Macewicz LL, Gan AM, Goncharov SV, Pawelec P, Portnichenko GV, Lapikova-Bryginska TY, Navrulin VO, Dosenko VE, Olichwier A, Dobrzyn P, Piven OO.

Pflugers Arch. 2018 Oct;470(10):1485-1499. doi: 10.1007/s00424-018-2168-2. Epub 2018 Jun 20. Erratum in: Pflugers Arch. 2018 Jul 4;:.


Images - Well-differentiated papillary mesothelioma of the tunica vaginalis.

Gan AML, Plantinga P, Punjani N, Hussey A, Power N.

Can Urol Assoc J. 2018 May 14. doi: 10.5489/cuaj.4940. [Epub ahead of print] No abstract available.


Spatial analysis of macro-level bicycle crashes using the class of conditional autoregressive models.

Saha D, Alluri P, Gan A, Wu W.

Accid Anal Prev. 2018 Sep;118:166-177. doi: 10.1016/j.aap.2018.02.014. Epub 2018 Feb 22.


The effects of bi-functional anti-adhesion scaffolds on flexor tendon healing in a rabbit model.

Liao JCY, He M, Gan AWT, Wen F, Tan LP, Chong AKS.

J Biomed Mater Res B Appl Biomater. 2018 Oct;106(7):2605-2614. doi: 10.1002/jbm.b.34077. Epub 2018 Feb 9.


Diet soft drink is associated with increased odds of proliferative diabetic retinopathy.

Fenwick EK, Gan AT, Man RE, Sabanayagam C, Gupta P, Khoo K, Aravindhan A, Wong TY, Lamoureux EL.

Clin Exp Ophthalmol. 2018 Sep;46(7):767-776. doi: 10.1111/ceo.13154. Epub 2018 Feb 23.


Development and Validation of a Deep Learning System for Diabetic Retinopathy and Related Eye Diseases Using Retinal Images From Multiethnic Populations With Diabetes.

Ting DSW, Cheung CY, Lim G, Tan GSW, Quang ND, Gan A, Hamzah H, Garcia-Franco R, San Yeo IY, Lee SY, Wong EYM, Sabanayagam C, Baskaran M, Ibrahim F, Tan NC, Finkelstein EA, Lamoureux EL, Wong IY, Bressler NM, Sivaprasad S, Varma R, Jonas JB, He MG, Cheng CY, Cheung GCM, Aung T, Hsu W, Lee ML, Wong TY.

JAMA. 2017 Dec 12;318(22):2211-2223. doi: 10.1001/jama.2017.18152.


Ethnic Differences in the Prevalence and Risk Factors of Diabetic Retinopathy: The Singapore Epidemiology of Eye Diseases Study.

Tan GS, Gan A, Sabanayagam C, Tham YC, Neelam K, Mitchell P, Wang JJ, Lamoureux EL, Cheng CY, Wong TY.

Ophthalmology. 2018 Apr;125(4):529-536. doi: 10.1016/j.ophtha.2017.10.026. Epub 2017 Dec 6.


Association Between Perceived Barriers to Diabetes Self-management and Diabetic Retinopathy in Asian Patients With Type 2 Diabetes.

Man REK, Fenwick EK, Gan ATL, Sabanayagam C, Gupta P, Aravindhan A, Wong TY, Tan GSW, Lamoureux EL.

JAMA Ophthalmol. 2017 Dec 1;135(12):1387-1393. doi: 10.1001/jamaophthalmol.2017.4888.


Retinal vasculature and 5-year metabolic syndrome among women with gestational diabetes mellitus.

Li LJ, Tan KH, Aris IM, Man REK, Gan ATL, Chong YS, Saw SM, Gluckman P, Wong TY, Lamoureux E.

Metabolism. 2018 Jun;83:216-224. doi: 10.1016/j.metabol.2017.10.004. Epub 2017 Oct 16.


Genetically Determined Plasma Lipid Levels and Risk of Diabetic Retinopathy: A Mendelian Randomization Study.

Sobrin L, Chong YH, Fan Q, Gan A, Stanwyck LK, Kaidonis G, Craig JE, Kim J, Liao WL, Huang YC, Lee WJ, Hung YJ, Guo X, Hai Y, Ipp E, Pollack S, Hancock H, Price A, Penman A, Mitchell P, Liew G, Smith AV, Gudnason V, Tan G, Klein BEK, Kuo J, Li X, Christiansen MW, Psaty BM, Sandow K; Asian Genetic Epidemiology Network Consortium, Jensen RA, Klein R, Cotch MF, Wang JJ, Jia Y, Chen CJ, Chen YI, Rotter JI, Tsai FJ, Hanis CL, Burdon KP, Wong TY, Cheng CY.

Diabetes. 2017 Dec;66(12):3130-3141. doi: 10.2337/db17-0398. Epub 2017 Sep 26.


The Effects of Autologous Platelet-Rich Fibrin on Flexor Tendon Healing in a Rabbit Model.

Liao JCY, He M, Gan AWT, Chong AKS.

J Hand Surg Am. 2017 Nov;42(11):928.e1-928.e7. doi: 10.1016/j.jhsa.2017.06.098. Epub 2017 Aug 9.


Plasma lipoprotein subfraction concentrations are associated with lipid metabolism and age-related macular degeneration.

Cheung CMG, Gan A, Fan Q, Chee ML, Apte RS, Khor CC, Yeo I, Mathur R, Cheng CY, Wong TY, Tai ES.

J Lipid Res. 2017 Sep;58(9):1785-1796. doi: 10.1194/jlr.M073684. Epub 2017 Jul 11.


Randomized phase II placebo-controlled study to evaluate the efficacy of topical pure emu oil for joint pain related to adjuvant aromatase inhibitor use in postmenopausal women with early breast cancer: JUST (Joints Under Study).

Chan A, De Boer R, Gan A, Willsher P, Martin R, Zissiadis Y, Miller K, Bauwens A, Hastrich D.

Support Care Cancer. 2017 Dec;25(12):3785-3791. doi: 10.1007/s00520-017-3810-9. Epub 2017 Jul 9.


Change in vision-related quality of life and influencing factors in Asians receiving treatment for neovascular age-related macular degeneration.

Fenwick EK, Cheung GCM, Gan AT, Tan G, Lee SY, Wong D, Yeo I, Mathur R, Wong TY, Lamoureux EL.

Br J Ophthalmol. 2018 Mar;102(3):377-382. doi: 10.1136/bjophthalmol-2017-310532. Epub 2017 Jun 28.


Cumulative incidence and risk factors of prediabetes and type 2 diabetes in a Singaporean Malay cohort.

Man REK, Charumathi S, Gan ATL, Fenwick EK, Tey CS, Chua J, Wong TY, Cheng CY, Lamoureux EL.

Diabetes Res Clin Pract. 2017 May;127:163-171. doi: 10.1016/j.diabres.2017.03.007. Epub 2017 Mar 22.


Ethnic Differences in the Association Between Age-Related Macular Degeneration and Vision-Specific Functioning.

Fenwick EK, Man REK, Cheung CMG, Sabanayagam C, Cheng CY, Neelam K, Chua J, Gan ATL, Mitchell P, Wong TY, Lamoureux EL.

JAMA Ophthalmol. 2017 May 1;135(5):469-476. doi: 10.1001/jamaophthalmol.2017.0266.


Retinal angiomatous proliferation.

Tsai ASH, Cheung N, Gan ATL, Jaffe GJ, Sivaprasad S, Wong TY, Cheung CMG.

Surv Ophthalmol. 2017 Jul - Aug;62(4):462-492. doi: 10.1016/j.survophthal.2017.01.008. Epub 2017 Feb 9. Review.


Multiregion ultra-deep sequencing reveals early intermixing and variable levels of intratumoral heterogeneity in colorectal cancer.

Suzuki Y, Ng SB, Chua C, Leow WQ, Chng J, Liu SY, Ramnarayanan K, Gan A, Ho DL, Ten R, Su Y, Lezhava A, Lai JH, Koh D, Lim KH, Tan P, Rozen SG, Tan IB.

Mol Oncol. 2017 Feb;11(2):124-139. doi: 10.1002/1878-0261.12012. Epub 2016 Oct 20.


Prevalence, Risk Factors, and Impact of Undiagnosed Visually Significant Cataract: The Singapore Epidemiology of Eye Diseases Study.

Chua J, Lim B, Fenwick EK, Gan AT, Tan AG, Lamoureux E, Mitchell P, Wang JJ, Wong TY, Cheng CY.

PLoS One. 2017 Jan 27;12(1):e0170804. doi: 10.1371/journal.pone.0170804. eCollection 2017.


Individualised multiplexed circulating tumour DNA assays for monitoring of tumour presence in patients after colorectal cancer surgery.

Ng SB, Chua C, Ng M, Gan A, Poon PS, Teo M, Fu C, Leow WQ, Lim KH, Chung A, Koo SL, Choo SP, Ho D, Rozen S, Tan P, Wong M, Burkholder WF, Tan IB.

Sci Rep. 2017 Jan 19;7:40737. doi: 10.1038/srep40737.


Type 2 Diabetes Genetic Variants and Risk of Diabetic Retinopathy.

Chong YH, Fan Q, Tham YC, Gan A, Tan SP, Tan G, Wang JJ, Mitchell P, Wong TY, Cheng CY.

Ophthalmology. 2017 Mar;124(3):336-342. doi: 10.1016/j.ophtha.2016.11.016. Epub 2016 Dec 27.


Human retinal microvascular imaging using adaptive optics scanning light ophthalmoscopy.

Chui TYP, Mo S, Krawitz B, Menon NR, Choudhury N, Gan A, Razeen M, Shah N, Pinhas A, Rosen RB.

Int J Retina Vitreous. 2016 May 1;2:11. doi: 10.1186/s40942-016-0037-8. eCollection 2016. Review.


Stearoyl-CoA desaturase 1 deficiency reduces lipid accumulation in the heart by activating lipolysis independently of peroxisome proliferator-activated receptor α.

Bednarski T, Olichwier A, Opasinska A, Pyrkowska A, Gan AM, Ntambi JM, Dobrzyn P.

Biochim Biophys Acta. 2016 Dec;1861(12 Pt A):2029-2037. doi: 10.1016/j.bbalip.2016.10.005. Epub 2016 Oct 15.


A Bayesian procedure for evaluating the frequency of calibration factor updates in highway safety manual (HSM) applications.

Saha D, Alluri P, Gan A.

Accid Anal Prev. 2017 Jan;98:74-86. doi: 10.1016/j.aap.2016.09.027. Epub 2016 Oct 1.


Amendment of the cytokine profile in macrophages subsequent to their interaction with smooth muscle cells: Differential modulation by fractalkine and resistin.

Tucureanu MM, Butoi E, Gan AM, Stan D, Constantinescu CA, Calin M, Simionescu M, Manduteanu I.

Cytokine. 2016 Jul;83:250-261. doi: 10.1016/j.cyto.2016.04.019. Epub 2016 May 12.


Diagnostic Performance of DNA Hypermethylation Markers in Peripheral Blood for the Detection of Colorectal Cancer: A Meta-Analysis and Systematic Review.

Li B, Gan A, Chen X, Wang X, He W, Zhang X, Huang R, Zhou S, Song X, Xu A.

PLoS One. 2016 May 9;11(5):e0155095. doi: 10.1371/journal.pone.0155095. eCollection 2016. Review.


Cross-talk between macrophages and smooth muscle cells impairs collagen and metalloprotease synthesis and promotes angiogenesis.

Butoi E, Gan AM, Tucureanu MM, Stan D, Macarie RD, Constantinescu C, Calin M, Simionescu M, Manduteanu I.

Biochim Biophys Acta. 2016 Jul;1863(7 Pt A):1568-78. doi: 10.1016/j.bbamcr.2016.04.001. Epub 2016 Apr 7.


Longitudinal imaging of microvascular remodelling in proliferative diabetic retinopathy using adaptive optics scanning light ophthalmoscopy.

Chui TY, Pinhas A, Gan A, Razeen M, Shah N, Cheang E, Liu CL, Dubra A, Rosen RB.

Ophthalmic Physiol Opt. 2016 May;36(3):290-302. doi: 10.1111/opo.12273. Epub 2016 Jan 24.


Conjugation of curcumin-loaded lipid nanoemulsions with cell-penetrating peptides increases their cellular uptake and enhances the anti-inflammatory effects in endothelial cells.

Simion V, Stan D, Constantinescu CA, Deleanu M, Dragan E, Tucureanu MM, Gan AM, Butoi E, Constantin A, Manduteanu I, Simionescu M, Calin M.

J Pharm Pharmacol. 2016 Feb;68(2):195-207. doi: 10.1111/jphp.12513. Epub 2016 Jan 8.


Safety performance evaluation of cable median barriers on freeways in Florida.

Alluri P, Haleem K, Gan A, Mauthner J.

Traffic Inj Prev. 2016 Jul 3;17(5):544-51. doi: 10.1080/15389588.2015.1101079. Epub 2015 Oct 27.


Interpretation of hip fracture patterns using areal bone mineral density in the proximal femur.

Hey HW, Sng WJ, Lim JL, Tan CS, Gan AT, Ng JH, Kagda FH.

Arch Orthop Trauma Surg. 2015 Dec;135(12):1647-53. doi: 10.1007/s00402-015-2326-3. Epub 2015 Sep 21.


Bone Marrow Derived Mesenchymal Stem Cell Augmentation of Rabbit Flexor Tendon Healing.

He M, Gan AW, Lim AY, Goh JC, Hui JH, Chong AK.

Hand Surg. 2015 Oct;20(3):421-9. doi: 10.1142/S0218810415500343.


SETD2 histone modifier loss in aggressive GI stromal tumours.

Huang KK, McPherson JR, Tay ST, Das K, Tan IB, Ng CC, Chia NY, Zhang SL, Myint SS, Hu L, Rajasegaran V, Huang D, Loh JL, Gan A, Sairi AN, Sam XX, Dominguez LT, Lee M, Soo KC, Ooi LL, Ong HS, Chung A, Chow PK, Wong WK, Selvarajan S, Ong CK, Lim KH, Nandi T, Rozen S, Teh BT, Quek R, Tan P.

Gut. 2016 Dec;65(12):1960-1972. doi: 10.1136/gutjnl-2015-309482. Epub 2015 Sep 3.


Mutation signatures implicate aristolochic acid in bladder cancer development.

Poon SL, Huang MN, Choo Y, McPherson JR, Yu W, Heng HL, Gan A, Myint SS, Siew EY, Ler LD, Ng LG, Weng WH, Chuang CK, Yuen JS, Pang ST, Tan P, Teh BT, Rozen SG.

Genome Med. 2015 Apr 28;7(1):38. doi: 10.1186/s13073-015-0161-3. eCollection 2015.


Analyzing pedestrian crash injury severity at signalized and non-signalized locations.

Haleem K, Alluri P, Gan A.

Accid Anal Prev. 2015 Aug;81:14-23. doi: 10.1016/j.aap.2015.04.025. Epub 2015 May 2.


Contributing factors of crash injury severity at public highway-railroad grade crossings in the U.S.

Haleem K, Gan A.

J Safety Res. 2015 Jun;53:23-9. doi: 10.1016/j.jsr.2015.03.005. Epub 2015 Mar 21.


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