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Items: 16


Upregulation of Myt1 Promotes Acquired Resistance of Cancer Cells to Wee1 Inhibition.

Lewis CW, Bukhari AB, Xiao EJ, Choi WS, Smith JD, Homola E, Mackey JR, Campbell SD, Gamper AM, Chan GK.

Cancer Res. 2019 Dec 1;79(23):5971-5985. doi: 10.1158/0008-5472.CAN-19-1961. Epub 2019 Oct 8.


Inhibiting Wee1 and ATR kinases produces tumor-selective synthetic lethality and suppresses metastasis.

Bukhari AB, Lewis CW, Pearce JJ, Luong D, Chan GK, Gamper AM.

J Clin Invest. 2019 Mar 1;129(3):1329-1344. doi: 10.1172/JCI122622. Epub 2019 Feb 18.


Human DNA polymerase ε is phosphorylated at serine-1940 after DNA damage and interacts with the iron-sulfur complex chaperones CIAO1 and MMS19.

Moiseeva TN, Gamper AM, Hood BL, Conrads TP, Bakkenist CJ.

DNA Repair (Amst). 2016 Jul;43:9-17. doi: 10.1016/j.dnarep.2016.04.007. Epub 2016 May 7.


Restricted protein phosphatase 2A targeting by Merkel cell polyomavirus small T antigen.

Kwun HJ, Shuda M, Camacho CJ, Gamper AM, Thant M, Chang Y, Moore PS.

J Virol. 2015 Apr;89(8):4191-200. doi: 10.1128/JVI.00157-15. Epub 2015 Jan 28.


ATR kinase activation in G1 phase facilitates the repair of ionizing radiation-induced DNA damage.

Gamper AM, Rofougaran R, Watkins SC, Greenberger JS, Beumer JH, Bakkenist CJ.

Nucleic Acids Res. 2013 Dec;41(22):10334-44. doi: 10.1093/nar/gkt833. Epub 2013 Sep 14.


ATM protein physically and functionally interacts with proliferating cell nuclear antigen to regulate DNA synthesis.

Gamper AM, Choi S, Matsumoto Y, Banerjee D, Tomkinson AE, Bakkenist CJ.

J Biol Chem. 2012 Apr 6;287(15):12445-54. doi: 10.1074/jbc.M112.352310. Epub 2012 Feb 23.


Regulation of KLF4 turnover reveals an unexpected tissue-specific role of pVHL in tumorigenesis.

Gamper AM, Qiao X, Kim J, Zhang L, DeSimone MC, Rathmell WK, Wan Y.

Mol Cell. 2012 Jan 27;45(2):233-43. doi: 10.1016/j.molcel.2011.11.031. Erratum in: Mol Cell. 2015 Oct 15;60(2):339.


APC/C-Cdh1: from cell cycle to cellular differentiation and genomic integrity.

Qiao X, Zhang L, Gamper AM, Fujita T, Wan Y.

Cell Cycle. 2010 Oct 1;9(19):3904-12. Epub 2010 Oct 11. Review.


The STAGA subunit ADA2b is an important regulator of human GCN5 catalysis.

Gamper AM, Kim J, Roeder RG.

Mol Cell Biol. 2009 Jan;29(1):266-80. doi: 10.1128/MCB.00315-08. Epub 2008 Oct 20.


Multivalent binding of p53 to the STAGA complex mediates coactivator recruitment after UV damage.

Gamper AM, Roeder RG.

Mol Cell Biol. 2008 Apr;28(8):2517-27. doi: 10.1128/MCB.01461-07. Epub 2008 Feb 4.


Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration.

Palhan VB, Chen S, Peng GH, Tjernberg A, Gamper AM, Fan Y, Chait BT, La Spada AR, Roeder RG.

Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8472-7. Epub 2005 Jun 2.


Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo.

Martinez E, Palhan VB, Tjernberg A, Lymar ES, Gamper AM, Kundu TK, Chait BT, Roeder RG.

Mol Cell Biol. 2001 Oct;21(20):6782-95.


Comparative molecular field analysis of haptens docked to the multispecific antibody IgE(Lb4)

Gamper AM, Winger RH, Liedl KR, Sotriffer CA, Varga JM, Kroemer RT, Rode BM.

J Med Chem. 1996 Sep 27;39(20):3882-8. Erratum in: J Med Chem 1997 Mar 14;40(6):1047-8.


Prediction of IgE(Lb4)-ligand complex structures by automated docking.

Winger RH, Liedl KR, Sotriffer CA, Gamper AM, Rode BM, Kroemer RT, Varga JM.

J Mol Recognit. 1996 May-Jun;9(3):239-46.


Heteroligation of a mouse monoclonal IgE antibody (La2) with small molecules, analysed by computer-aided automated docking.

Sotriffer CA, Liedl KR, Winger RH, Gamper AM, Kroemer RT, Linthicum DS, Rode BM, Varga JM.

Mol Immunol. 1996 Feb;33(2):129-44.


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