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Items: 30


Combining hyperpolarized real-time metabolic imaging and NMR spectroscopy to identify metabolic biomarkers in pancreatic cancer.

Dutta P, Perez MR, Lee J, Kang Y, Pratt M, Salzillo TC, Weygand J, Zacharias NM, Gammon ST, Koay EJ, Kim M, McAllister F, Sen S, Maitra A, Piwnica-Worms D, Fleming JB, Bhattacharya PK.

J Proteome Res. 2019 May 23. doi: 10.1021/acs.jproteome.9b00132. [Epub ahead of print]


Multiwalled Carbon Nanotubes for Combination Therapy: a Biodistribution and Efficacy Pilot Study.

Biagiotti G, Pisaneschi F, Gammon ST, Machetti F, Ligi MC, Giambastiani G, Tuci G, Powell E, Piwnica-Worms H, Pranzini E, Paoli P, Cicchi S, Piwnica-Worms D.

J Mater Chem B. 2019 Apr 28;7(16):2678-2687. doi: 10.1039/C8TB03299H. Epub 2019 Mar 12.


Assessing Therapeutic Efficacy in Real-time by Hyperpolarized Magnetic Resonance Metabolic Imaging.

Dutta P, Salzillo TC, Pudakalakatti S, Gammon ST, Kaipparettu BA, McAllister F, Wagner S, Frigo DE, Logothetis CJ, Zacharias NM, Bhattacharya PK.

Cells. 2019 Apr 11;8(4). pii: E340. doi: 10.3390/cells8040340. Review.


Caspase-3 Substrates for Noninvasive Pharmacodynamic Imaging of Apoptosis by PET/CT.

Engel BJ, Gammon ST, Chaudhari R, Lu Z, Pisaneschi F, Yang H, Ornelas A, Yan V, Kelderhouse L, Najjar AM, Tong WP, Zhang S, Piwnica-Worms D, Bast RC Jr, Millward SW.

Bioconjug Chem. 2018 Sep 19;29(9):3180-3195. doi: 10.1021/acs.bioconjchem.8b00514. Epub 2018 Aug 31.


Interrogating Metabolism in Brain Cancer.

Salzillo TC, Hu J, Nguyen L, Whiting N, Lee J, Weygand J, Dutta P, Pudakalakatti S, Millward NZ, Gammon ST, Lang FF, Heimberger AB, Bhattacharya PK.

Magn Reson Imaging Clin N Am. 2016 Nov;24(4):687-703. doi: 10.1016/j.mric.2016.07.003. Review.


Directed Evolution of Scanning Unnatural-Protease-Resistant (SUPR) Peptides for in Vivo Applications.

Fiacco SV, Kelderhouse LE, Hardy A, Peleg Y, Hu B, Ornelas A, Yang P, Gammon ST, Howell SM, Wang P, Takahashi TT, Millward SW, Roberts RW.

Chembiochem. 2016 Sep 2;17(17):1643-51. doi: 10.1002/cbic.201600253. Epub 2016 Jul 28.


Glypican-1 identifies cancer exosomes and detects early pancreatic cancer.

Melo SA, Luecke LB, Kahlert C, Fernandez AF, Gammon ST, Kaye J, LeBleu VS, Mittendorf EA, Weitz J, Rahbari N, Reissfelder C, Pilarsky C, Fraga MF, Piwnica-Worms D, Kalluri R.

Nature. 2015 Jul 9;523(7559):177-82. doi: 10.1038/nature14581. Epub 2015 Jun 24.


Preclinical anatomical, molecular, and functional imaging of the lung with multiple modalities.

Gammon ST, Foje N, Brewer EM, Owers E, Downs CA, Budde MD, Leevy WM, Helms MN.

Am J Physiol Lung Cell Mol Physiol. 2014 May 15;306(10):L897-914. doi: 10.1152/ajplung.00007.2014. Epub 2014 Mar 21. Review.


Single-cell resolution imaging of retinal ganglion cell apoptosis in vivo using a cell-penetrating caspase-activatable peptide probe.

Qiu X, Johnson JR, Wilson BS, Gammon ST, Piwnica-Worms D, Barnett EM.

PLoS One. 2014 Feb 21;9(2):e88855. doi: 10.1371/journal.pone.0088855. eCollection 2014.


Bacterial infection probes and imaging strategies in clinical nuclear medicine and preclinical molecular imaging.

Sasser TA, Van Avermaete AE, White A, Chapman S, Johnson JR, Van Avermaete T, Gammon ST, Leevy WM.

Curr Top Med Chem. 2013;13(4):479-87. Review.


A bioluminescent transposon reporter-trap identifies tumor-specific microenvironment-induced promoters in Salmonella for conditional bacterial-based tumor therapy.

Flentie K, Kocher B, Gammon ST, Novack DV, McKinney JS, Piwnica-Worms D.

Cancer Discov. 2012 Jul;2(7):624-37. doi: 10.1158/2159-8290.CD-11-0201. Epub 2012 May 3.


Segmentation and measurement of fat volumes in murine obesity models using X-ray computed tomography.

Sasser TA, Chapman SE, Li S, Hudson C, Orton SP, Diener JM, Gammon ST, Correcher C, Leevy WM.

J Vis Exp. 2012 Apr 4;(62):e3680. doi: 10.3791/3680.


Salmonella typhimurium infections in BALB/c mice: a comparison of tissue bioluminescence, tissue cultures and mice clinical scores.

Özkaya H, Akcan AB, Aydemir G, Aydinöz S, Razia Y, Gammon ST, McKinney J.

New Microbiol. 2012 Jan;35(1):53-9. Epub 2012 Jan 10.


In vivo cell death mediated by synthetic ion channels.

Smith BA, Daschbach MM, Gammon ST, Xiao S, Chapman SE, Hudson C, Suckow M, Piwnica-Worms D, Gokel GW, Leevy WM.

Chem Commun (Camb). 2011 Jul 28;47(28):7977-9. doi: 10.1039/c1cc12933c. Epub 2011 Jun 17.


In vivo optical imaging of acute cell death using a near-infrared fluorescent zinc-dipicolylamine probe.

Smith BA, Gammon ST, Xiao S, Wang W, Chapman S, McDermott R, Suckow MA, Johnson JR, Piwnica-Worms D, Gokel GW, Smith BD, Leevy WM.

Mol Pharm. 2011 Apr 4;8(2):583-90. doi: 10.1021/mp100395u. Epub 2011 Mar 1.


Targeted chemotherapy in drug-resistant tumors, noninvasive imaging of P-glycoprotein-mediated functional transport in cancer, and emerging role of Pgp in neurodegenerative diseases.

Sivapackiam J, Gammon ST, Harpstrite SE, Sharma V.

Methods Mol Biol. 2010;596:141-81. doi: 10.1007/978-1-60761-416-6_8.


Rational design of novel red-shifted BRET pairs: Platforms for real-time single-chain protease biosensors.

Gammon ST, Villalobos VM, Roshal M, Samrakandi M, Piwnica-Worms D.

Biotechnol Prog. 2009 Mar-Apr;25(2):559-69. doi: 10.1002/btpr.144.


Bioluminescence imaging of myeloperoxidase activity in vivo.

Gross S, Gammon ST, Moss BL, Rauch D, Harding J, Heinecke JW, Ratner L, Piwnica-Worms D.

Nat Med. 2009 Apr;15(4):455-61. doi: 10.1038/nm.1886. Epub 2009 Mar 22.


Stably integrated luxCDABE for assessment of Salmonella invasion kinetics.

Flentie KN, Qi M, Gammon ST, Razia Y, Lui F, Marpegan L, Manglik A, Piwnica-Worms D, McKinney JS.

Mol Imaging. 2008 Sep-Oct;7(5):222-33.


Noninvasive optical imaging of staphylococcus aureus bacterial infection in living mice using a Bis-dipicolylamine-Zinc(II) affinity group conjugated to a near-infrared fluorophore.

Leevy WM, Gammon ST, Johnson JR, Lampkins AJ, Jiang H, Marquez M, Piwnica-Worms D, Suckow MA, Smith BD.

Bioconjug Chem. 2008 Mar;19(3):686-92. doi: 10.1021/bc700376v. Epub 2008 Feb 9.


Identification of a ligand-induced transient refractory period in nuclear factor-kappaB signaling.

Moss BL, Gross S, Gammon ST, Vinjamoori A, Piwnica-Worms D.

J Biol Chem. 2008 Mar 28;283(13):8687-98. doi: 10.1074/jbc.M706831200. Epub 2008 Jan 17.


A method for quantification of nucleotides and nucleotide analogues in thymidine kinase assays using lanthanum phosphate coprecipitation.

Gammon ST, Bernstein M, Schuster DP, Piwnica-Worms D.

Anal Biochem. 2007 Oct 1;369(1):80-6. Epub 2007 Jun 15.


Squaraine rotaxanes: superior substitutes for Cy-5 in molecular probes for near-infrared fluorescence cell imaging.

Johnson JR, Fu N, Arunkumar E, Leevy WM, Gammon ST, Piwnica-Worms D, Smith BD.

Angew Chem Int Ed Engl. 2007;46(29):5528-31. No abstract available.


Optical imaging of bacterial infection in living mice using a fluorescent near-infrared molecular probe.

Leevy WM, Gammon ST, Jiang H, Johnson JR, Maxwell DJ, Jackson EN, Marquez M, Piwnica-Worms D, Smith BD.

J Am Chem Soc. 2006 Dec 27;128(51):16476-7.


Linkage between cellular communications, energy utilization, and proliferation in metastatic neuroendocrine cancers.

Ippolito JE, Merritt ME, Bäckhed F, Moulder KL, Mennerick S, Manchester JK, Gammon ST, Piwnica-Worms D, Gordon JI.

Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12505-10. Epub 2006 Aug 8.


Permeation peptide conjugates for in vivo molecular imaging applications.

Bullok KE, Gammon ST, Violini S, Prantner AM, Villalobos VM, Sharma V, Piwnica-Worms D.

Mol Imaging. 2006 Jan-Mar;5(1):1-15. Review.


Spectral unmixing of multicolored bioluminescence emitted from heterogeneous biological sources.

Gammon ST, Leevy WM, Gross S, Gokel GW, Piwnica-Worms D.

Anal Chem. 2006 Mar 1;78(5):1520-7.


Structure-activity relationships, kinetics, selectivity, and mechanistic studies of synthetic hydraphile channels in bacterial and mammalian cells.

Leevy WM, Gammon ST, Levchenko T, Daranciang DD, Murillo O, Torchilin V, Piwnica-Worms D, Huettner JE, Gokel GW.

Org Biomol Chem. 2005 Oct 7;3(19):3544-50. Epub 2005 Aug 26.


Kinetics of regulated protein-protein interactions revealed with firefly luciferase complementation imaging in cells and living animals.

Luker KE, Smith MC, Luker GD, Gammon ST, Piwnica-Worms H, Piwnica-Worms D.

Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12288-93. Epub 2004 Jul 29.


Quantitative analysis of permeation peptide complexes labeled with Technetium-99m: chiral and sequence-specific effects on net cell uptake.

Gammon ST, Villalobos VM, Prior JL, Sharma V, Piwnica-Worms D.

Bioconjug Chem. 2003 Mar-Apr;14(2):368-76.


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