Sort by
Items per page

Send to

Choose Destination

Search results

Items: 41


IL-36 promotes anti-viral immunity by boosting sensitivity to IFN-α/β in IRF1 dependent and independent manners.

Wang P, Gamero AM, Jensen LE.

Nat Commun. 2019 Oct 16;10(1):4700. doi: 10.1038/s41467-019-12318-y.


Characterization of cancer-associated IDH2 mutations that differ in tumorigenicity, chemosensitivity and 2-hydroxyglutarate production.

Kotredes KP, Razmpour R, Lutton E, Alfonso-Prieto M, Ramirez SH, Gamero AM.

Oncotarget. 2019 Apr 12;10(28):2675-2692. doi: 10.18632/oncotarget.26848. eCollection 2019 Apr 12.


STAT2 dependent Type I Interferon response promotes dysbiosis and luminal expansion of the enteric pathogen Salmonella Typhimurium.

Wilson RP, Tursi SA, Rapsinski GJ, Medeiros NJ, Le LS, Kotredes KP, Patel S, Liverani E, Sun S, Zhu W, Kilpatrick L, Winter SE, Gamero AM, Tükel Ç.

PLoS Pathog. 2019 Apr 22;15(4):e1007745. doi: 10.1371/journal.ppat.1007745. eCollection 2019 Apr.


Interferon-γ Signaling in Melanocytes and Melanoma Cells Regulates Expression of CTLA-4.

Mo X, Zhang H, Preston S, Martin K, Zhou B, Vadalia N, Gamero AM, Soboloff J, Tempera I, Zaidi MR.

Cancer Res. 2018 Jan 15;78(2):436-450. doi: 10.1158/0008-5472.CAN-17-1615. Epub 2017 Nov 17.


The Protective Role of Type I Interferons in the Gastrointestinal Tract.

Kotredes KP, Thomas B, Gamero AM.

Front Immunol. 2017 Apr 6;8:410. doi: 10.3389/fimmu.2017.00410. eCollection 2017. Review.


Prostaglandin E2 Inhibition of IL-27 Production in Murine Dendritic Cells: A Novel Mechanism That Involves IRF1.

Hooper KM, Yen JH, Kong W, Rahbari KM, Kuo PC, Gamero AM, Ganea D.

J Immunol. 2017 Feb 15;198(4):1521-1530. doi: 10.4049/jimmunol.1601073. Epub 2017 Jan 6.


Phosphorylation of STAT2 on serine-734 negatively regulates the IFN-α-induced antiviral response.

Steen HC, Kotredes KP, Nogusa S, Harris MY, Balachandran S, Gamero AM.

J Cell Sci. 2016 Nov 15;129(22):4190-4199. Epub 2016 Oct 19.


STAT2 Is Required for TLR-Induced Murine Dendritic Cell Activation and Cross-Presentation.

Xu J, Lee MH, Chakhtoura M, Green BL, Kotredes KP, Chain RW, Sriram U, Gamero AM, Gallucci S.

J Immunol. 2016 Jul 1;197(1):326-36. doi: 10.4049/jimmunol.1500152. Epub 2016 May 27.


Type I interferon restricts type 2 immunopathology through the regulation of group 2 innate lymphoid cells.

Duerr CU, McCarthy CD, Mindt BC, Rubio M, Meli AP, Pothlichet J, Eva MM, Gauchat JF, Qureshi ST, Mazer BD, Mossman KL, Malo D, Gamero AM, Vidal SM, King IL, Sarfati M, Fritz JH.

Nat Immunol. 2016 Jan;17(1):65-75. doi: 10.1038/ni.3308. Epub 2015 Nov 23.


Stat1 Regulates Lupus-like Chronic Graft-versus-Host Disease Severity via Interactions with Stat3.

Shao WH, Gamero AM, Zhen Y, Lobue MJ, Priest SO, Albandar HJ, Cohen PL.

J Immunol. 2015 Nov 1;195(9):4136-43. doi: 10.4049/jimmunol.1501353. Epub 2015 Sep 21.


Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages.

McComb S, Cessford E, Alturki NA, Joseph J, Shutinoski B, Startek JB, Gamero AM, Mossman KL, Sad S.

Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):E3206-13. doi: 10.1073/pnas.1407068111. Epub 2014 Jul 21.


An essential role for IFN-β in the induction of IFN-stimulated gene expression by LPS in macrophages.

Sheikh F, Dickensheets H, Gamero AM, Vogel SN, Donnelly RP.

J Leukoc Biol. 2014 Oct;96(4):591-600. doi: 10.1189/jlb.2A0414-191R. Epub 2014 Jul 14.


Host STAT2/type I interferon axis controls tumor growth.

Yue C, Xu J, Tan Estioko MD, Kotredes KP, Lopez-Otalora Y, Hilliard BA, Baker DP, Gallucci S, Gamero AM.

Int J Cancer. 2015 Jan 1;136(1):117-26. doi: 10.1002/ijc.29004. Epub 2014 Jun 17.


TLR ligands up-regulate Trex1 expression in murine conventional dendritic cells through type I Interferon and NF-κB-dependent signaling pathways.

Xu J, Zoltick PW, Gamero AM, Gallucci S.

J Leukoc Biol. 2014 Jul;96(1):93-103. doi: 10.1189/jlb.2A0713-393RR. Epub 2014 Mar 5.


STAT2 phosphorylation and signaling.

Steen HC, Gamero AM.

JAKSTAT. 2013 Oct 1;2(4):e25790. doi: 10.4161/jkst.25790. Epub 2013 Aug 12. Review.


Stat2 loss leads to cytokine-independent, cell-mediated lethality in LPS-induced sepsis.

Alazawi W, Heath H, Waters JA, Woodfin A, O'Brien AJ, Scarzello AJ, Ma B, Lopez-Otalora Y, Jacobs M, Petts G, Goldin RD, Nourshargh S, Gamero AM, Foster GR.

Proc Natl Acad Sci U S A. 2013 May 21;110(21):8656-61. doi: 10.1073/pnas.1221652110. Epub 2013 May 7.


Interferons as inducers of apoptosis in malignant cells.

Kotredes KP, Gamero AM.

J Interferon Cytokine Res. 2013 Apr;33(4):162-70. doi: 10.1089/jir.2012.0110. Review.


Identification of STAT2 serine 287 as a novel regulatory phosphorylation site in type I interferon-induced cellular responses.

Steen HC, Nogusa S, Thapa RJ, Basagoudanavar SH, Gill AL, Merali S, Barrero CA, Balachandran S, Gamero AM.

J Biol Chem. 2013 Jan 4;288(1):747-58. doi: 10.1074/jbc.M112.402529. Epub 2012 Nov 8.


The role of signal transducer and activator of transcription-2 in the interferon response.

Steen HC, Gamero AM.

J Interferon Cytokine Res. 2012 Mar;32(3):103-10. doi: 10.1089/jir.2011.0099. Epub 2012 Jan 26. Review.


Control of type I interferon-induced cell death by Orai1-mediated calcium entry in T cells.

Yue C, Soboloff J, Gamero AM.

J Biol Chem. 2012 Jan 27;287(5):3207-16. doi: 10.1074/jbc.M111.269068. Epub 2011 Dec 5.


Cecal ligation puncture procedure.

Toscano MG, Ganea D, Gamero AM.

J Vis Exp. 2011 May 7;(51). pii: 2860. doi: 10.3791/2860.


Interferon-lambda as a potential therapeutic agent in cancer treatment.

Steen HC, Gamero AM.

J Interferon Cytokine Res. 2010 Aug;30(8):597-602. doi: 10.1089/jir.2010.0058. Review.


STAT2 contributes to promotion of colorectal and skin carcinogenesis.

Gamero AM, Young MR, Mentor-Marcel R, Bobe G, Scarzello AJ, Wise J, Colburn NH.

Cancer Prev Res (Phila). 2010 Apr;3(4):495-504. doi: 10.1158/1940-6207.CAPR-09-0105. Epub 2010 Mar 16.


Resistance to IFN-alpha-induced apoptosis is linked to a loss of STAT2.

Romero-Weaver AL, Wang HW, Steen HC, Scarzello AJ, Hall VL, Sheikh F, Donnelly RP, Gamero AM.

Mol Cancer Res. 2010 Jan;8(1):80-92. doi: 10.1158/1541-7786.MCR-08-0344. Epub 2010 Jan 12.


IFNalpha and IFNlambda differ in their antiproliferative effects and duration of JAK/STAT signaling activity.

Maher SG, Sheikh F, Scarzello AJ, Romero-Weaver AL, Baker DP, Donnelly RP, Gamero AM.

Cancer Biol Ther. 2008 Jul;7(7):1109-15. Epub 2008 Apr 24.


Interferon: cellular executioner or white knight?

Maher SG, Romero-Weaver AL, Scarzello AJ, Gamero AM.

Curr Med Chem. 2007;14(12):1279-89. Review.


A Mutation in the SH2 domain of STAT2 prolongs tyrosine phosphorylation of STAT1 and promotes type I IFN-induced apoptosis.

Scarzello AJ, Romero-Weaver AL, Maher SG, Veenstra TD, Zhou M, Qin A, Donnelly RP, Sheikh F, Gamero AM.

Mol Biol Cell. 2007 Jul;18(7):2455-62. Epub 2007 Apr 18.


Activation of Tyk2 and Stat3 is required for the apoptotic actions of interferon-beta in primary pro-B cells.

Gamero AM, Potla R, Wegrzyn J, Szelag M, Edling AE, Shimoda K, Link DC, Dulak J, Baker DP, Tanabe Y, Grayson JM, Larner AC.

J Biol Chem. 2006 Jun 16;281(24):16238-44. Epub 2006 Apr 6.


IL-1 can act as number one.

Gamero AM, Oppenheim JJ.

Immunity. 2006 Jan;24(1):16-7.


Type I interferons activate apoptosis in a Jurkat cell variant by caspase-dependent and independent mechanisms.

Gamero AM, Potla R, Sakamoto S, Baker DP, Abraham R, Larner AC.

Cell Signal. 2006 Aug;18(8):1299-308. Epub 2005 Dec 6.


Calcium-dependent activation of interleukin-21 gene expression in T cells.

Kim HP, Korn LL, Gamero AM, Leonard WJ.

J Biol Chem. 2005 Jul 1;280(26):25291-7. Epub 2005 May 6.


Inactivation of Stat3 in tumor cells: releasing a brake on immune responses against cancer?

Gamero AM, Young HA, Wiltrout RH.

Cancer Cell. 2004 Feb;5(2):111-2. Review.


Thrombomodulin RNA is destabilized through its 3'-untranslated element in cells exposed to IFN-gamma.

Navarro A, Frevel M, Gamero AM, Williams BR, Feldman G, Larner AC.

J Interferon Cytokine Res. 2003 Dec;23(12):723-8.


Identification of a novel conserved motif in the STAT family that is required for tyrosine phosphorylation.

Gamero AM, Sakamoto S, Montenegro J, Larner AC.

J Biol Chem. 2004 Mar 26;279(13):12379-85. Epub 2004 Jan 13.


Effects of interferon beta on transcobalamin II-receptor expression and antitumor activity of nitrosylcobalamin.

Bauer JA, Morrison BH, Grane RW, Jacobs BS, Dabney S, Gamero AM, Carnevale KA, Smith DJ, Drazba J, Seetharam B, Lindner DJ.

J Natl Cancer Inst. 2002 Jul 3;94(13):1010-9.


Vanadate facilitates interferon alpha-mediated apoptosis that is dependent on the Jak/Stat pathway.

Gamero AM, Larner AC.

J Biol Chem. 2001 Apr 27;276(17):13547-53. Epub 2001 Jan 19.


Functional association of TGF-beta receptor II with cyclin B.

Liu JH, Wei S, Burnette PK, Gamero AM, Hutton M, Djeu JY.

Oncogene. 1999 Jan 7;18(1):269-75.


Critical role of Lyn kinase in inhibition of neutrophil apoptosis by granulocyte-macrophage colony-stimulating factor.

Wei S, Liu JH, Epling-Burnette PK, Gamero AM, Ussery D, Pearson EW, Elkabani ME, Diaz JI, Djeu JY.

J Immunol. 1996 Dec 1;157(11):5155-62.


Supplemental Content

Loading ...
Support Center