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Items: 1 to 50 of 712

1.

Engineering of a novel subnanomolar affinity fibronectin III domain binder targeting human programmed death-ligand 1.

Ramakrishnan S, Natarajan A, Chan CT, Panesar PS, Gambhir SS.

Protein Eng Des Sel. 2019 Oct 15. pii: gzz030. doi: 10.1093/protein/gzz030. [Epub ahead of print]

PMID:
31612217
2.

Evaluation of integrin αvβ6 cystine knot PET tracers to detect cancer and idiopathic pulmonary fibrosis.

Kimura RH, Wang L, Shen B, Huo L, Tummers W, Filipp FV, Guo HH, Haywood T, Abou-Elkacem L, Baratto L, Habte F, Devulapally R, Witney TH, Cheng Y, Tikole S, Chakraborti S, Nix J, Bonagura CA, Hatami N, Mooney JJ, Desai T, Turner S, Gaster RS, Otte A, Visser BC, Poultsides GA, Norton J, Park W, Stolowitz M, Lau K, Yang E, Natarajan A, Ilovich O, Srinivas S, Srinivasan A, Paulmurugan R, Willmann J, Chin FT, Cheng Z, Iagaru A, Li F, Gambhir SS.

Nat Commun. 2019 Oct 14;10(1):4673. doi: 10.1038/s41467-019-11863-w.

3.

Initial experience with a PET/computed tomography system using silicon photomultiplier detectors.

Park SY, Barrato L, Hatami N, Davidzon G, Gambhir SS, Iagaru A.

Nucl Med Commun. 2019 Nov;40(11):1174-1178. doi: 10.1097/MNM.0000000000001088.

PMID:
31568189
4.

Simultaneous transrectal ultrasound and photoacoustic human prostate imaging.

Kothapalli SR, Sonn GA, Choe JW, Nikoozadeh A, Bhuyan A, Park KK, Cristman P, Fan R, Moini A, Lee BC, Wu J, Carver TE, Trivedi D, Shiiba L, Steinberg I, Huland DM, Rasmussen MF, Liao JC, Brooks JD, Khuri-Yakub PT, Gambhir SS.

Sci Transl Med. 2019 Aug 28;11(507). pii: eaav2169. doi: 10.1126/scitranslmed.aav2169.

PMID:
31462508
5.

Microvesicle-mediated delivery of minicircle DNA results in effective gene-directed enzyme prodrug cancer therapy.

Kanada M, Kim BD, Hardy JW, Ronald JA, Bachmann MH, Bernard MP, Perez GI, Zarea AA, Ge TJ, Withrow A, Ibrahim SA, Toomajian V, Gambhir SS, Paulmurugan R, Contag CH.

Mol Cancer Ther. 2019 Aug 26. pii: molcanther.0299.2019. doi: 10.1158/1535-7163.MCT-19-0299. [Epub ahead of print]

PMID:
31451563
6.

Continuous-Wave Coherent Raman Spectroscopy via Plasmonic Enhancement.

Monfared YE, Shaffer TM, Gambhir SS, Hewitt KC.

Sci Rep. 2019 Aug 20;9(1):12092. doi: 10.1038/s41598-019-48573-8.

7.

Improved detection of prostate cancer using a magneto-nanosensor assay for serum circulating autoantibodies.

Xu L, Lee JR, Hao S, Ling XB, Brooks JD, Wang SX, Gambhir SS.

PLoS One. 2019 Aug 12;14(8):e0221051. doi: 10.1371/journal.pone.0221051. eCollection 2019.

8.

Intranasal delivery of targeted polyfunctional gold-iron oxide nanoparticles loaded with therapeutic microRNAs for combined theranostic multimodality imaging and presensitization of glioblastoma to temozolomide.

Sukumar UK, Bose RJC, Malhotra M, Babikir HA, Afjei R, Robinson E, Zeng Y, Chang E, Habte F, Sinclair R, Gambhir SS, Massoud TF, Paulmurugan R.

Biomaterials. 2019 Oct;218:119342. doi: 10.1016/j.biomaterials.2019.119342. Epub 2019 Jul 12.

PMID:
31326657
9.

Ultrasound/microbubble-mediated targeted delivery of anticancer microRNA-loaded nanoparticles to deep tissues in pigs.

Di Ianni T, Bose RJC, Sukumar UK, Bachawal S, Wang H, Telichko A, Herickhoff C, Robinson E, Baker S, Vilches-Moure JG, Felt SA, Gambhir SS, Paulmurugan R, Dahl JD.

J Control Release. 2019 Sep 10;309:1-10. doi: 10.1016/j.jconrel.2019.07.024. Epub 2019 Jul 18.

PMID:
31326463
10.

Photoacoustic clinical imaging.

Steinberg I, Huland DM, Vermesh O, Frostig HE, Tummers WS, Gambhir SS.

Photoacoustics. 2019 Jun 8;14:77-98. doi: 10.1016/j.pacs.2019.05.001. eCollection 2019 Jun. Review.

11.

Author Correction: Miniature gold nanorods for photoacoustic molecular imaging in the second near-infrared optical window.

Chen YS, Zhao Y, Yoon SJ, Gambhir SS, Emelianov S.

Nat Nanotechnol. 2019 Aug;14(8):810. doi: 10.1038/s41565-019-0522-y.

PMID:
31289408
12.

Simultaneous PET/MRI in the Evaluation of Breast and Prostate Cancer Using Combined Na[18F] F and [18F]FDG: a Focus on Skeletal Lesions.

Sonni I, Minamimoto R, Baratto L, Gambhir SS, Loening AM, Vasanawala SS, Iagaru A.

Mol Imaging Biol. 2019 Jun 24. doi: 10.1007/s11307-019-01392-9. [Epub ahead of print]

PMID:
31236756
13.

The characterization of 18F-hGTS13 for molecular imaging of xC- transporter activity with positron emission tomography.

Beinat C, Gowrishankar G, Shen B, Alam IS, Robinson E, Haywood T, Patel CB, Azevedo EC, Castillo J, Ilovich O, Koglin N, Schmitt-Willich H, Berndt M, Mueller A, Zerna M, Srinivasan A, Gambhir SS.

J Nucl Med. 2019 Jun 6. pii: jnumed.119.225870. doi: 10.2967/jnumed.119.225870. [Epub ahead of print]

PMID:
31171595
14.

Positron emission tomography reporter gene strategy for use in the central nervous system.

Haywood T, Beinat C, Gowrishankar G, Patel CB, Alam IS, Murty S, Gambhir SS.

Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11402-11407. doi: 10.1073/pnas.1901645116. Epub 2019 May 23.

PMID:
31123153
15.

How to Prevent a Leaky Pipeline in Academic Radiology: Insights From a Faculty Survey.

Daldrup-Link H, Villavasso K, Zhao Q, Lu Y, Ranieri A, Simard C, Gambhir SS.

J Am Coll Radiol. 2019 Sep;16(9 Pt A):1220-1224. doi: 10.1016/j.jacr.2019.04.008. Epub 2019 May 16. No abstract available.

PMID:
31092345
16.

Evaluation of Glycolytic Response to Multiple Classes of Anti-glioblastoma Drugs by Noninvasive Measurement of Pyruvate Kinase M2 Using [18F]DASA-23.

Beinat C, Patel CB, Xie Y, Gambhir SS.

Mol Imaging Biol. 2019 Apr 15. doi: 10.1007/s11307-019-01353-2. [Epub ahead of print]

PMID:
30989436
17.

[18F]-SuPAR: A Radiofluorinated Probe for Noninvasive Imaging of DNA Damage-Dependent Poly(ADP-ribose) Polymerase Activity.

Shuhendler AJ, Cui L, Chen Z, Shen B, Chen M, James ML, Witney TH, Bazalova-Carter M, Gambhir SS, Chin FT, Graves EE, Rao J.

Bioconjug Chem. 2019 May 15;30(5):1331-1342. doi: 10.1021/acs.bioconjchem.9b00089. Epub 2019 Apr 22.

PMID:
30973715
18.

Engineered immune cells as highly sensitive cancer diagnostics.

Aalipour A, Chuang HY, Murty S, D'Souza AL, Park SM, Gulati GS, Patel CB, Beinat C, Simonetta F, Martinić I, Gowrishankar G, Robinson ER, Aalipour E, Zhian Z, Gambhir SS.

Nat Biotechnol. 2019 May;37(5):531-539. doi: 10.1038/s41587-019-0064-8. Epub 2019 Mar 18.

PMID:
30886438
19.

Proceedings: Pathways for Successful Translation of New Imaging Agents and Modalities-Phase III Studies.

Gambhir SS, Shankar LK, Rosenthal E, Warram JM, Ghesani M, Hope TA, Jacobs PM, Jacobson GB, Wilson T, Siegel BA.

J Nucl Med. 2019 Jun;60(6):736-744. doi: 10.2967/jnumed.118.219824. Epub 2019 Mar 8. No abstract available.

PMID:
30850482
20.

Miniature gold nanorods for photoacoustic molecular imaging in the second near-infrared optical window.

Chen YS, Zhao Y, Yoon SJ, Gambhir SS, Emelianov S.

Nat Nanotechnol. 2019 May;14(5):465-472. doi: 10.1038/s41565-019-0392-3. Epub 2019 Mar 4. Erratum in: Nat Nanotechnol. 2019 Aug;14(8):810.

21.

In Vivo Translation of the CIRPI System: Revealing Molecular Pathology of Rabbit Aortic Atherosclerotic Plaques.

Zaman RT, Yousefi S, Chibana H, Ikeno F, Long SR, Gambhir SS, Chin FT, McConnell MV, Xing L, Yeung A.

J Nucl Med. 2019 Sep;60(9):1308-1316. doi: 10.2967/jnumed.118.222471. Epub 2019 Feb 8.

PMID:
30737298
22.

Detection of visually occult metastatic lymph nodes using molecularly targeted fluorescent imaging during surgical resection of pancreatic cancer.

Tummers WS, Miller SE, Teraphongphom NT, van den Berg NS, Hasan A, Longacre TA, Fisher GA, Bonsing BA, Vahrmeijer AL, Gambhir SS, Swijnenburg RJ, Rosenthal EL, Poultsides GA.

HPB (Oxford). 2019 Jul;21(7):883-890. doi: 10.1016/j.hpb.2018.11.008. Epub 2019 Feb 2.

PMID:
30723062
23.

Nanomedicine for Spontaneous Brain Tumors: A Companion Clinical Trial.

Arami H, Patel CB, Madsen SJ, Dickinson PJ, Davis RM, Zeng Y, Sturges BK, Woolard KD, Habte FG, Akin D, Sinclair R, Gambhir SS.

ACS Nano. 2019 Mar 26;13(3):2858-2869. doi: 10.1021/acsnano.8b04406. Epub 2019 Feb 4.

24.

Detection of Premalignant Gastrointestinal Lesions Using Surface-Enhanced Resonance Raman Scattering-Nanoparticle Endoscopy.

Harmsen S, Rogalla S, Huang R, Spaliviero M, Neuschmelting V, Hayakawa Y, Lee Y, Tailor Y, Toledo-Crow R, Kang JW, Samii JM, Karabeber H, Davis RM, White JR, van de Rijn M, Gambhir SS, Contag CH, Wang TC, Kircher MF.

ACS Nano. 2019 Feb 26;13(2):1354-1364. doi: 10.1021/acsnano.8b06808. Epub 2019 Feb 4.

25.

Tumor treating fields increases membrane permeability in glioblastoma cells.

Chang E, Patel CB, Pohling C, Young C, Song J, Flores TA, Zeng Y, Joubert LM, Arami H, Natarajan A, Sinclair R, Gambhir SS.

Cell Death Discov. 2018 Dec 5;4:113. doi: 10.1038/s41420-018-0130-x. eCollection 2018.

26.

An intravascular magnetic wire for the high-throughput retrieval of circulating tumour cells in vivo.

Vermesh O, Aalipour A, Ge TJ, Saenz Y, Guo Y, Alam IS, Park SM, Adelson CN, Mitsutake Y, Vilches-Moure J, Godoy E, Bachmann MH, Ooi CC, Lyons JK, Mueller K, Arami H, Green A, Solomon EI, Wang SX, Gambhir SS.

Nat Biomed Eng. 2018 Sep;2(9):696-705. doi: 10.1038/s41551-018-0257-3. Epub 2018 Jul 16.

27.

Striatal dopamine deficits predict reductions in striatal functional connectivity in major depression: a concurrent 11C-raclopride positron emission tomography and functional magnetic resonance imaging investigation.

Hamilton JP, Sacchet MD, Hjørnevik T, Chin FT, Shen B, Kämpe R, Park JH, Knutson BD, Williams LM, Borg N, Zaharchuk G, Camacho MC, Mackey S, Heilig M, Drevets WC, Glover GH, Gambhir SS, Gotlib IH.

Transl Psychiatry. 2018 Nov 30;8(1):264. doi: 10.1038/s41398-018-0316-2.

28.

Discussions with Leaders: A Conversation Between Sam Gambhir and Johannes Czernin.

Czernin J, Gambhir SS.

J Nucl Med. 2018 Dec;59(12):1783-1785. doi: 10.2967/jnumed.118.221648. No abstract available.

PMID:
30510073
29.

Assessment of Tumor Redox Status through (S)-4-(3-[18F]fluoropropyl)-L-Glutamic Acid PET Imaging of System xc - Activity.

McCormick PN, Greenwood HE, Glaser M, Maddocks ODK, Gendron T, Sander K, Gowrishankar G, Hoehne A, Zhang T, Shuhendler AJ, Lewis DY, Berndt M, Koglin N, Lythgoe MF, Gambhir SS, Årstad E, Witney TH.

Cancer Res. 2019 Feb 15;79(4):853-863. doi: 10.1158/0008-5472.CAN-18-2634. Epub 2018 Nov 6.

30.

Treating mucormycosis using a multimodality approach: a case series.

Gupta AK, Parwal C, Mangal M, Gambhir SS, Nanda BS, Sarangi K.

J Wound Care. 2018 Nov 2;27(11):735-742. doi: 10.12968/jowc.2018.27.11.735.

PMID:
30398934
31.

A Novel Engineered Small Protein for Positron Emission Tomography Imaging of Human Programmed Death Ligand-1: Validation in Mouse Models and Human Cancer Tissues.

Natarajan A, Patel CB, Ramakrishnan S, Panesar PS, Long SR, Gambhir SS.

Clin Cancer Res. 2019 Mar 15;25(6):1774-1785. doi: 10.1158/1078-0432.CCR-18-1871. Epub 2018 Oct 29.

PMID:
30373750
32.

Tumor Cell-Derived Extracellular Vesicle-Coated Nanocarriers: An Efficient Theranostic Platform for the Cancer-Specific Delivery of Anti-miR-21 and Imaging Agents.

Bose RJC, Uday Kumar S, Zeng Y, Afjei R, Robinson E, Lau K, Bermudez A, Habte F, Pitteri SJ, Sinclair R, Willmann JK, Massoud TF, Gambhir SS, Paulmurugan R.

ACS Nano. 2018 Nov 27;12(11):10817-10832. doi: 10.1021/acsnano.8b02587. Epub 2018 Oct 22.

PMID:
30346694
33.

Surface-Enhanced Raman Scattering Nanoparticles for Multiplexed Imaging of Bladder Cancer Tissue Permeability and Molecular Phenotype.

Davis RM, Kiss B, Trivedi DR, Metzner TJ, Liao JC, Gambhir SS.

ACS Nano. 2018 Oct 23;12(10):9669-9679. doi: 10.1021/acsnano.8b03217. Epub 2018 Sep 11.

34.

Osseous Metaplasia Mimicking Long Bone in Intramuscular Vascular Malformation.

Panda R, Mangal M, Reddy S, Gupta A, Gambhir SS, Nanda BS.

World J Plast Surg. 2018 May;7(2):243-248.

35.

Quantification of Cerenkov Luminescence Imaging (CLI) Comparable With 3-D PET Standard Measurements.

Habte F, Natarajan A, Paik DS, Gambhir SS.

Mol Imaging. 2018 Jan-Dec;17:1536012118788637. doi: 10.1177/1536012118788637.

36.

Ferumoxytol-based Dual-modality Imaging Probe for Detection of Stem Cell Transplant Rejection.

Li K, Chan CT, Nejadnik H, Lenkov OD, Wolterman C, Paulmurugan R, Yang H, Gambhir SS, Daldrup-Link HE.

Nanotheranostics. 2018 Jun 23;2(4):306-319. doi: 10.7150/ntno.26389. eCollection 2018.

37.

Emerging Intraoperative Imaging Modalities to Improve Surgical Precision.

Alam IS, Steinberg I, Vermesh O, van den Berg NS, Rosenthal EL, van Dam GM, Ntziachristos V, Gambhir SS, Hernot S, Rogalla S.

Mol Imaging Biol. 2018 Oct;20(5):705-715. doi: 10.1007/s11307-018-1227-6. Review.

PMID:
29916118
38.

A Dual-Modality Hybrid Imaging System Harnesses Radioluminescence and Sound to Reveal Molecular Pathology of Atherosclerotic Plaques.

Zaman RT, Yousefi S, Long SR, Saito T, Mandella M, Qiu Z, Chen R, Contag CH, Gambhir SS, Chin FT, Khuri-Yakub BT, McConnell MV, Shung KK, Xing L.

Sci Rep. 2018 Jun 12;8(1):8992. doi: 10.1038/s41598-018-26696-8.

39.

Advances in Diagnostic and Intraoperative Molecular Imaging of Pancreatic Cancer.

Tummers WS, Willmann JK, Bonsing BA, Vahrmeijer AL, Gambhir SS, Swijnenburg RJ.

Pancreas. 2018 Jul;47(6):675-689. doi: 10.1097/MPA.0000000000001075. Review.

40.

Development and MPI tracking of novel hypoxia-targeted theranostic exosomes.

Jung KO, Jo H, Yu JH, Gambhir SS, Pratx G.

Biomaterials. 2018 Sep;177:139-148. doi: 10.1016/j.biomaterials.2018.05.048. Epub 2018 May 29.

41.

Towards clinically translatable in vivo nanodiagnostics.

Park SM, Aalipour A, Vermesh O, Yu JH, Gambhir SS.

Nat Rev Mater. 2017 May;2(5). pii: 17014. doi: 10.1038/natrevmats.2017.14. Epub 2017 May 3.

42.

The Immunoimaging Toolbox.

Mayer AT, Gambhir SS.

J Nucl Med. 2018 Aug;59(8):1174-1182. doi: 10.2967/jnumed.116.185967. Epub 2018 May 24. Review.

43.

The Utility of [18F]DASA-23 for Molecular Imaging of Prostate Cancer with Positron Emission Tomography.

Beinat C, Haywood T, Chen YS, Patel CB, Alam IS, Murty S, Gambhir SS.

Mol Imaging Biol. 2018 Dec;20(6):1015-1024. doi: 10.1007/s11307-018-1194-y.

PMID:
29736561
44.

A blood biomarker for monitoring response to anti-EGFR therapy.

Hughes NP, Xu L, Nielsen CH, Chang E, Hori SS, Natarajan A, Lee S, Kjær A, Kani K, Wang SX, Mallick P, Gambhir SS.

Cancer Biomark. 2018;22(2):333-344. doi: 10.3233/CBM-171149.

PMID:
29689709
45.

Intraoperative Pancreatic Cancer Detection using Tumor-Specific Multimodality Molecular Imaging.

Tummers WS, Miller SE, Teraphongphom NT, Gomez A, Steinberg I, Huland DM, Hong S, Kothapalli SR, Hasan A, Ertsey R, Bonsing BA, Vahrmeijer AL, Swijnenburg RJ, Longacre TA, Fisher GA, Gambhir SS, Poultsides GA, Rosenthal EL.

Ann Surg Oncol. 2018 Jul;25(7):1880-1888. doi: 10.1245/s10434-018-6453-2. Epub 2018 Apr 17.

46.

Initial experience with a SiPM-based PET/CT scanner: influence of acquisition time on image quality.

Sonni I, Baratto L, Park S, Hatami N, Srinivas S, Davidzon G, Gambhir SS, Iagaru A.

EJNMMI Phys. 2018 Apr 18;5(1):9. doi: 10.1186/s40658-018-0207-x.

47.

Reply: 6″-18F-Fluoromaltotriose PET Evaluation in Escherichia Coli-Induced Myositis: Is There Uptake Saturation in Control?

Wardak M, Gowrishankar G, Gambhir SS.

J Nucl Med. 2018 Jul;59(7):1166-1167. doi: 10.2967/jnumed.118.208736. Epub 2018 Apr 13. No abstract available.

48.

Smart-Dust-Nanorice for Enhancement of Endogenous Raman Signal, Contrast in Photoacoustic Imaging, and T2-Shortening in Magnetic Resonance Imaging.

Pohling C, Campbell JL, Larson TA, Van de Sompel D, Levi J, Bachmann MH, Bohndiek SE, Jokerst JV, Gambhir SS.

Small. 2018 May;14(19):e1703683. doi: 10.1002/smll.201703683. Epub 2018 Apr 10.

49.

Molecular imaging agents for ultrasound.

Zlitni A, Gambhir SS.

Curr Opin Chem Biol. 2018 Aug;45:113-120. doi: 10.1016/j.cbpa.2018.03.017. Epub 2018 Apr 7. Review.

50.

Imaging activated T cells predicts response to cancer vaccines.

Alam IS, Mayer AT, Sagiv-Barfi I, Wang K, Vermesh O, Czerwinski DK, Johnson EM, James ML, Levy R, Gambhir SS.

J Clin Invest. 2018 Jun 1;128(6):2569-2580. doi: 10.1172/JCI98509. Epub 2018 May 14.

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