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Tumor treating fields increases membrane permeability in glioblastoma cells.

Chang E, Patel CB, Pohling C, Young C, Song J, Flores TA, Zeng Y, Joubert LM, Arami H, Natarajan A, Sinclair R, Gambhir SS.

Cell Death Discov. 2018 Dec 5;4:113. doi: 10.1038/s41420-018-0130-x. eCollection 2018.


An intravascular magnetic wire for the high-throughput retrieval of circulating tumour cells in vivo.

Vermesh O, Aalipour A, Ge TJ, Saenz Y, Guo Y, Alam IS, Park SM, Adelson CN, Mitsutake Y, Vilches-Moure J, Godoy E, Bachmann MH, Ooi CC, Lyons JK, Mueller K, Arami H, Green A, Solomon EI, Wang SX, Gambhir SS.

Nat Biomed Eng. 2018 Sep;2(9):696-705. doi: 10.1038/s41551-018-0257-3. Epub 2018 Jul 16.


Striatal dopamine deficits predict reductions in striatal functional connectivity in major depression: a concurrent 11C-raclopride positron emission tomography and functional magnetic resonance imaging investigation.

Hamilton JP, Sacchet MD, Hjørnevik T, Chin FT, Shen B, Kämpe R, Park JH, Knutson BD, Williams LM, Borg N, Zaharchuk G, Camacho MC, Mackey S, Heilig M, Drevets WC, Glover GH, Gambhir SS, Gotlib IH.

Transl Psychiatry. 2018 Nov 30;8(1):264. doi: 10.1038/s41398-018-0316-2.


Discussions with Leaders: A Conversation Between Sam Gambhir and Johannes Czernin.

Czernin J, Gambhir SS.

J Nucl Med. 2018 Dec;59(12):1783-1785. doi: 10.2967/jnumed.118.221648. No abstract available.


Assessment of tumor redox status through (S)-4-(3-[18F]fluoropropyl)-L-glutamic acid positron emission tomography imaging of system xc- activity.

McCormick PN, Greenwood HE, Glaser M, Maddocks ODK, Gendron T, Sander K, Gowrishankar G, Hoehne A, Zhang T, Shuhendler AJ, Lewis DY, Berndt M, Koglin N, Lythgoe MF, Gambhir SS, Årstad E, Witney TH.

Cancer Res. 2018 Nov 6. pii: canres.2634.2018. doi: 10.1158/0008-5472.CAN-18-2634. [Epub ahead of print]


Treating mucormycosis using a multimodality approach: a case series.

Gupta AK, Parwal C, Mangal M, Gambhir SS, Nanda BS, Sarangi K.

J Wound Care. 2018 Nov 2;27(11):735-742. doi: 10.12968/jowc.2018.27.11.735.


A Novel Engineered Small Protein for Positron Emission Tomography Imaging of Human Programmed Death Ligand-1 : Validation in Mouse Models and Human Cancer Tissues.

Natarajan A, Patel CB, Ramakrishnan S, Panesar PS, Long SR, Gambhir SS.

Clin Cancer Res. 2018 Oct 29. pii: clincanres.1871.2018. doi: 10.1158/1078-0432.CCR-18-1871. [Epub ahead of print]


Tumor Cell-Derived Extracellular Vesicle-Coated Nanocarriers: An Efficient Theranostic Platform for the Cancer-Specific Delivery of Anti-miR-21 and Imaging Agents.

Jc Bose R, Uday Kumar S, Zeng Y, Afjei R, Robinson E, Lau K, Bermudez A, Habte F, Pitteri SJ, Sinclair R, Willmann JK, Massoud TF, Gambhir SS, Paulmurugan R.

ACS Nano. 2018 Nov 27;12(11):10817-10832. doi: 10.1021/acsnano.8b02587. Epub 2018 Oct 22.


Surface-Enhanced Raman Scattering Nanoparticles for Multiplexed Imaging of Bladder Cancer Tissue Permeability and Molecular Phenotype.

Davis RM, Kiss B, Trivedi DR, Metzner TJ, Liao JC, Gambhir SS.

ACS Nano. 2018 Oct 23;12(10):9669-9679. doi: 10.1021/acsnano.8b03217. Epub 2018 Sep 11.


Osseous Metaplasia Mimicking Long Bone in Intramuscular Vascular Malformation.

Panda R, Mangal M, Reddy S, Gupta A, Gambhir SS, Nanda BS.

World J Plast Surg. 2018 May;7(2):243-248.


Quantification of Cerenkov Luminescence Imaging (CLI) Comparable With 3-D PET Standard Measurements.

Habte F, Natarajan A, Paik DS, Gambhir SS.

Mol Imaging. 2018 Jan-Dec;17:1536012118788637. doi: 10.1177/1536012118788637.


Ferumoxytol-based Dual-modality Imaging Probe for Detection of Stem Cell Transplant Rejection.

Li K, Chan CT, Nejadnik H, Lenkov OD, Wolterman C, Paulmurugan R, Yang H, Gambhir SS, Daldrup-Link HE.

Nanotheranostics. 2018 Jun 23;2(4):306-319. doi: 10.7150/ntno.26389. eCollection 2018.


Emerging Intraoperative Imaging Modalities to Improve Surgical Precision.

Alam IS, Steinberg I, Vermesh O, van den Berg NS, Rosenthal EL, van Dam GM, Ntziachristos V, Gambhir SS, Hernot S, Rogalla S.

Mol Imaging Biol. 2018 Jun 18. doi: 10.1007/s11307-018-1227-6. [Epub ahead of print]


A Dual-Modality Hybrid Imaging System Harnesses Radioluminescence and Sound to Reveal Molecular Pathology of Atherosclerotic Plaques.

Zaman RT, Yousefi S, Long SR, Saito T, Mandella M, Qiu Z, Chen R, Contag CH, Gambhir SS, Chin FT, Khuri-Yakub BT, McConnell MV, Shung KK, Xing L.

Sci Rep. 2018 Jun 12;8(1):8992. doi: 10.1038/s41598-018-26696-8.


Advances in Diagnostic and Intraoperative Molecular Imaging of Pancreatic Cancer.

Tummers WS, Willmann JK, Bonsing BA, Vahrmeijer AL, Gambhir SS, Swijnenburg RJ.

Pancreas. 2018 Jul;47(6):675-689. doi: 10.1097/MPA.0000000000001075. Review.


Development and MPI tracking of novel hypoxia-targeted theranostic exosomes.

Jung KO, Jo H, Yu JH, Gambhir SS, Pratx G.

Biomaterials. 2018 Sep;177:139-148. doi: 10.1016/j.biomaterials.2018.05.048. Epub 2018 May 29.


Towards clinically translatable in vivo nanodiagnostics.

Park SM, Aalipour A, Vermesh O, Yu JH, Gambhir SS.

Nat Rev Mater. 2017 May;2(5). pii: 17014. doi: 10.1038/natrevmats.2017.14. Epub 2017 May 3.


The Immunoimaging Toolbox.

Mayer AT, Gambhir SS.

J Nucl Med. 2018 Aug;59(8):1174-1182. doi: 10.2967/jnumed.116.185967. Epub 2018 May 24.


The Utility of [18F]DASA-23 for Molecular Imaging of Prostate Cancer with Positron Emission Tomography.

Beinat C, Haywood T, Chen YS, Patel CB, Alam IS, Murty S, Gambhir SS.

Mol Imaging Biol. 2018 May 7. doi: 10.1007/s11307-018-1194-y. [Epub ahead of print]


A blood biomarker for monitoring response to anti-EGFR therapy.

Hughes NP, Xu L, Nielsen CH, Chang E, Hori SS, Natarajan A, Lee S, Kjær A, Kani K, Wang SX, Mallick P, Gambhir SS.

Cancer Biomark. 2018;22(2):333-344. doi: 10.3233/CBM-171149.


Intraoperative Pancreatic Cancer Detection using Tumor-Specific Multimodality Molecular Imaging.

Tummers WS, Miller SE, Teraphongphom NT, Gomez A, Steinberg I, Huland DM, Hong S, Kothapalli SR, Hasan A, Ertsey R, Bonsing BA, Vahrmeijer AL, Swijnenburg RJ, Longacre TA, Fisher GA, Gambhir SS, Poultsides GA, Rosenthal EL.

Ann Surg Oncol. 2018 Jul;25(7):1880-1888. doi: 10.1245/s10434-018-6453-2. Epub 2018 Apr 17.


Initial experience with a SiPM-based PET/CT scanner: influence of acquisition time on image quality.

Sonni I, Baratto L, Park S, Hatami N, Srinivas S, Davidzon G, Gambhir SS, Iagaru A.

EJNMMI Phys. 2018 Apr 18;5(1):9. doi: 10.1186/s40658-018-0207-x.


Reply: 6″-18F-Fluoromaltotriose PET Evaluation in Escherichia Coli-Induced Myositis: Is There Uptake Saturation in Control?

Wardak M, Gowrishankar G, Gambhir SS.

J Nucl Med. 2018 Jul;59(7):1166-1167. doi: 10.2967/jnumed.118.208736. Epub 2018 Apr 13. No abstract available.


Smart-Dust-Nanorice for Enhancement of Endogenous Raman Signal, Contrast in Photoacoustic Imaging, and T2-Shortening in Magnetic Resonance Imaging.

Pohling C, Campbell JL, Larson TA, Van de Sompel D, Levi J, Bachmann MH, Bohndiek SE, Jokerst JV, Gambhir SS.

Small. 2018 May;14(19):e1703683. doi: 10.1002/smll.201703683. Epub 2018 Apr 10.


Molecular imaging agents for ultrasound.

Zlitni A, Gambhir SS.

Curr Opin Chem Biol. 2018 Aug;45:113-120. doi: 10.1016/j.cbpa.2018.03.017. Epub 2018 Apr 7. Review.


Imaging activated T cells predicts response to cancer vaccines.

Alam IS, Mayer AT, Sagiv-Barfi I, Wang K, Vermesh O, Czerwinski DK, Johnson EM, James ML, Levy R, Gambhir SS.

J Clin Invest. 2018 Jun 1;128(6):2569-2580. doi: 10.1172/JCI98509. Epub 2018 May 14.


Tumor characterization by ultrasound-release of multiple protein and microRNA biomarkers, preclinical and clinical evidence.

D'Souza AL, Chevillet JR, Ghanouni P, Yan X, Tewari M, Gambhir SS.

PLoS One. 2018 Mar 16;13(3):e0194268. doi: 10.1371/journal.pone.0194268. eCollection 2018.


A PET imaging approach for determining EGFR mutation status for improved lung cancer patient management.

Sun X, Xiao Z, Chen G, Han Z, Liu Y, Zhang C, Sun Y, Song Y, Wang K, Fang F, Wang X, Lin Y, Xu L, Shao L, Li J, Cheng Z, Gambhir SS, Shen B.

Sci Transl Med. 2018 Mar 7;10(431). pii: eaan8840. doi: 10.1126/scitranslmed.aan8840.


Toward achieving precision health.

Gambhir SS, Ge TJ, Vermesh O, Spitler R.

Sci Transl Med. 2018 Feb 28;10(430). pii: eaao3612. doi: 10.1126/scitranslmed.aao3612. Review.


[18F]FSPG-PET reveals increased cystine/glutamate antiporter (xc-) activity in a mouse model of multiple sclerosis.

Hoehne A, James ML, Alam IS, Ronald JA, Schneider B, D'Souza A, Witney TH, Andrews LE, Cropper HC, Behera D, Gowrishankar G, Ding Z, Wyss-Coray T, Chin FT, Biswal S, Gambhir SS.

J Neuroinflammation. 2018 Feb 22;15(1):55. doi: 10.1186/s12974-018-1080-1.


Intraoperative Molecular Imaging in Lung Cancer: The State of the Art and the Future.

Rogalla S, Joosten SCM, Alam IS, Gambhir SS, Vermesh O.

Mol Ther. 2018 Feb 7;26(2):338-341. doi: 10.1016/j.ymthe.2018.01.013. Epub 2018 Feb 2. No abstract available.


Eradication of spontaneous malignancy by local immunotherapy.

Sagiv-Barfi I, Czerwinski DK, Levy S, Alam IS, Mayer AT, Gambhir SS, Levy R.

Sci Transl Med. 2018 Jan 31;10(426). pii: eaan4488. doi: 10.1126/scitranslmed.aan4488.


Reply: Optimizing Strategies for Immune Checkpoint Imaging with Immuno-PET in Preclinical Study.

Mayer AT, Gambhir SS.

J Nucl Med. 2018 Apr;59(4):711-712. doi: 10.2967/jnumed.117.205153. Epub 2018 Jan 18. No abstract available.


Dosimetry Prediction for Clinical Translation of 64Cu-Pembrolizumab ImmunoPET Targeting Human PD-1 Expression.

Natarajan A, Patel CB, Habte F, Gambhir SS.

Sci Rep. 2018 Jan 12;8(1):633. doi: 10.1038/s41598-017-19123-x.


A novel synthesis of 6''-[18 F]-fluoromaltotriose as a PET tracer for imaging bacterial infection.

Namavari M, Gowrishankar G, Srinivasan A, Gambhir SS, Haywood T, Beinat C.

J Labelled Comp Radiopharm. 2018 May 15;61(5):408-414. doi: 10.1002/jlcr.3601. Epub 2018 Mar 30.


Thy1-Targeted Microbubbles for Ultrasound Molecular Imaging of Pancreatic Ductal Adenocarcinoma.

Abou-Elkacem L, Wang H, Chowdhury SM, Kimura RH, Bachawal SV, Gambhir SS, Tian L, Willmann JK.

Clin Cancer Res. 2018 Apr 1;24(7):1574-1585. doi: 10.1158/1078-0432.CCR-17-2057. Epub 2018 Jan 4.


Development and Preclinical Validation of a Cysteine Knottin Peptide Targeting Integrin αvβ6 for Near-infrared Fluorescent-guided Surgery in Pancreatic Cancer.

Tummers WS, Kimura RH, Abou-Elkacem L, Beinat C, Vahrmeijer AL, Swijnenburg RJ, Willmann JK, Gambhir SS.

Clin Cancer Res. 2018 Apr 1;24(7):1667-1676. doi: 10.1158/1078-0432.CCR-17-2491. Epub 2018 Jan 3.


Future cancer research priorities in the USA: a Lancet Oncology Commission.

Jaffee EM, Dang CV, Agus DB, Alexander BM, Anderson KC, Ashworth A, Barker AD, Bastani R, Bhatia S, Bluestone JA, Brawley O, Butte AJ, Coit DG, Davidson NE, Davis M, DePinho RA, Diasio RB, Draetta G, Frazier AL, Futreal A, Gambhir SS, Ganz PA, Garraway L, Gerson S, Gupta S, Heath J, Hoffman RI, Hudis C, Hughes-Halbert C, Ibrahim R, Jadvar H, Kavanagh B, Kittles R, Le QT, Lippman SM, Mankoff D, Mardis ER, Mayer DK, McMasters K, Meropol NJ, Mitchell B, Naredi P, Ornish D, Pawlik TM, Peppercorn J, Pomper MG, Raghavan D, Ritchie C, Schwarz SW, Sullivan R, Wahl R, Wolchok JD, Wong SL, Yung A.

Lancet Oncol. 2017 Nov;18(11):e653-e706. doi: 10.1016/S1470-2045(17)30698-8. Epub 2017 Oct 31. Review.


High-throughput full-length single-cell mRNA-seq of rare cells.

Ooi CC, Mantalas GL, Koh W, Neff NF, Fuchigami T, Wong DJ, Wilson RJ, Park SM, Gambhir SS, Quake SR, Wang SX.

PLoS One. 2017 Nov 29;12(11):e0188510. doi: 10.1371/journal.pone.0188510. eCollection 2017.


Tomographic magnetic particle imaging of cancer targeted nanoparticles.

Arami H, Teeman E, Troksa A, Bradshaw H, Saatchi K, Tomitaka A, Gambhir SS, Häfeli UO, Liggitt D, Krishnan KM.

Nanoscale. 2017 Dec 7;9(47):18723-18730. doi: 10.1039/c7nr05502a.


A First Report on [18F]FPRGD2 PET/CT Imaging in Multiple Myeloma.

Withofs N, Cousin F, De Prijck B, Bonnet C, Hustinx R, Gambhir SS, Beguin Y, Caers J.

Contrast Media Mol Imaging. 2017 Jul 27;2017:6162845. doi: 10.1155/2017/6162845. eCollection 2017.


The Exosome Total Isolation Chip.

Liu F, Vermesh O, Mani V, Ge TJ, Madsen SJ, Sabour A, Hsu EC, Gowrishankar G, Kanada M, Jokerst JV, Sierra RG, Chang E, Lau K, Sridhar K, Bermudez A, Pitteri SJ, Stoyanova T, Sinclair R, Nair VS, Gambhir SS, Demirci U.

ACS Nano. 2017 Nov 28;11(11):10712-10723. doi: 10.1021/acsnano.7b04878. Epub 2017 Nov 1.


Prospective Evaluation of 68Ga-RM2 PET/MRI in Patients with Biochemical Recurrence of Prostate Cancer and Negative Findings on Conventional Imaging.

Minamimoto R, Sonni I, Hancock S, Vasanawala S, Loening A, Gambhir SS, Iagaru A.

J Nucl Med. 2018 May;59(5):803-808. doi: 10.2967/jnumed.117.197624. Epub 2017 Oct 30.


Deactivated CRISPR Associated Protein 9 for Minor-Allele Enrichment in Cell-Free DNA.

Aalipour A, Dudley JC, Park SM, Murty S, Chabon JJ, Boyle EA, Diehn M, Gambhir SS.

Clin Chem. 2018 Feb;64(2):307-316. doi: 10.1373/clinchem.2017.278911. Epub 2017 Oct 16.


Longitudinal Monitoring of Antibody Responses against Tumor Cells Using Magneto-nanosensors with a Nanoliter of Blood.

Lee JR, Chan CT, Ruderman D, Chuang HY, Gaster RS, Atallah M, Mallick P, Lowe SW, Gambhir SS, Wang SX.

Nano Lett. 2017 Nov 8;17(11):6644-6652. doi: 10.1021/acs.nanolett.7b02591. Epub 2017 Oct 20.


Visualizing Nerve Injury in a Neuropathic Pain Model with [18F]FTC-146 PET/MRI.

Shen B, Behera D, James ML, Reyes ST, Andrews L, Cipriano PW, Klukinov M, Lutz AB, Mavlyutov T, Rosenberg J, Ruoho AE, McCurdy CR, Gambhir SS, Yeomans DC, Biswal S, Chin FT.

Theranostics. 2017 Jul 8;7(11):2794-2805. doi: 10.7150/thno.19378. eCollection 2017.


Capture and Genetic Analysis of Circulating Tumor Cells Using a Magnetic Separation Device (Magnetic Sifter).

Ooi CC, Park SM, Wong DJ, Gambhir SS, Wang SX.

Methods Mol Biol. 2017;1634:153-162. doi: 10.1007/978-1-4939-7144-2_12.


Engineering Intracellularly Retained Gaussia Luciferase Reporters for Improved Biosensing and Molecular Imaging Applications.

Gaur S, Bhargava-Shah A, Hori S, Afjei R, Sekar TV, Gambhir SS, Massoud TF, Paulmurugan R.

ACS Chem Biol. 2017 Sep 15;12(9):2345-2353. doi: 10.1021/acschembio.7b00454. Epub 2017 Aug 10.


Imaging B Cells in a Mouse Model of Multiple Sclerosis Using 64Cu-Rituximab PET.

James ML, Hoehne A, Mayer AT, Lechtenberg K, Moreno M, Gowrishankar G, Ilovich O, Natarajan A, Johnson EM, Nguyen J, Quach L, Han M, Buckwalter M, Chandra S, Gambhir SS.

J Nucl Med. 2017 Nov;58(11):1845-1851. doi: 10.2967/jnumed.117.189597. Epub 2017 Jul 7.


Synergistic inhibition of glioma cell proliferation by Withaferin A and tumor treating fields.

Chang E, Pohling C, Beygui N, Patel CB, Rosenberg J, Ha DH, Gambhir SS.

J Neurooncol. 2017 Sep;134(2):259-268. doi: 10.1007/s11060-017-2534-5. Epub 2017 Jul 5.

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