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Items: 16

1.

Structure of the Cardiac Sodium Channel.

Jiang D, Shi H, Tonggu L, Gamal El-Din TM, Lenaeus MJ, Zhao Y, Yoshioka C, Zheng N, Catterall WA.

Cell. 2020 Jan 9;180(1):122-134.e10. doi: 10.1016/j.cell.2019.11.041. Epub 2019 Dec 19.

PMID:
31866066
2.

Structure and Pharmacology of Voltage-Gated Sodium and Calcium Channels.

Catterall WA, Lenaeus MJ, Gamal El-Din TM.

Annu Rev Pharmacol Toxicol. 2020 Jan 6;60:133-154. doi: 10.1146/annurev-pharmtox-010818-021757. Epub 2019 Sep 19.

PMID:
31537174
3.

Structural Basis for Diltiazem Block of a Voltage-Gated Ca2+ Channel.

Tang L, Gamal El-Din TM, Lenaeus MJ, Zheng N, Catterall WA.

Mol Pharmacol. 2019 Oct;96(4):485-492. doi: 10.1124/mol.119.117531. Epub 2019 Aug 7.

PMID:
31391290
4.

Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel.

Wisedchaisri G, Tonggu L, McCord E, Gamal El-Din TM, Wang L, Zheng N, Catterall WA.

Cell. 2019 Aug 8;178(4):993-1003.e12. doi: 10.1016/j.cell.2019.06.031. Epub 2019 Jul 25.

PMID:
31353218
5.

Fenestrations control resting-state block of a voltage-gated sodium channel.

Gamal El-Din TM, Lenaeus MJ, Zheng N, Catterall WA.

Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):13111-13116. doi: 10.1073/pnas.1814928115. Epub 2018 Dec 5.

6.

Molecular dissection of multiphase inactivation of the bacterial sodium channel NaVAb.

Gamal El-Din TM, Lenaeus MJ, Ramanadane K, Zheng N, Catterall WA.

J Gen Physiol. 2019 Feb 4;151(2):174-185. doi: 10.1085/jgp.201711884. Epub 2018 Dec 3.

7.

Structural basis for gating pore current in periodic paralysis.

Jiang D, Gamal El-Din TM, Ing C, Lu P, Pomès R, Zheng N, Catterall WA.

Nature. 2018 May;557(7706):590-594. doi: 10.1038/s41586-018-0120-4. Epub 2018 May 16.

8.

Structural and Functional Analysis of Sodium Channels Viewed from an Evolutionary Perspective.

Gamal El-Din TM, Lenaeus MJ, Catterall WA.

Handb Exp Pharmacol. 2018;246:53-72. doi: 10.1007/164_2017_61. Review.

PMID:
29043505
9.

Structures of closed and open states of a voltage-gated sodium channel.

Lenaeus MJ, Gamal El-Din TM, Ing C, Ramanadane K, Pomès R, Zheng N, Catterall WA.

Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):E3051-E3060. doi: 10.1073/pnas.1700761114. Epub 2017 Mar 27.

10.

Structural basis for inhibition of a voltage-gated Ca2+ channel by Ca2+ antagonist drugs.

Tang L, Gamal El-Din TM, Swanson TM, Pryde DC, Scheuer T, Zheng N, Catterall WA.

Nature. 2016 Sep 1;537(7618):117-121. doi: 10.1038/nature19102. Epub 2016 Aug 24.

11.

Tracking S4 movement by gating pore currents in the bacterial sodium channel NaChBac.

Gamal El-Din TM, Scheuer T, Catterall WA.

J Gen Physiol. 2014 Aug;144(2):147-57. doi: 10.1085/jgp.201411210.

12.

Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.

Tang L, Gamal El-Din TM, Payandeh J, Martinez GQ, Heard TM, Scheuer T, Zheng N, Catterall WA.

Nature. 2014 Jan 2;505(7481):56-61. doi: 10.1038/nature12775. Epub 2013 Nov 24.

13.

A gating charge interaction required for late slow inactivation of the bacterial sodium channel NavAb.

Gamal El-Din TM, Martinez GQ, Payandeh J, Scheuer T, Catterall WA.

J Gen Physiol. 2013 Sep;142(3):181-90. doi: 10.1085/jgp.201311012.

14.

Crystal structure of a voltage-gated sodium channel in two potentially inactivated states.

Payandeh J, Gamal El-Din TM, Scheuer T, Zheng N, Catterall WA.

Nature. 2012 May 20;486(7401):135-9. doi: 10.1038/nature11077.

15.

Double gaps along Shaker S4 demonstrate omega currents at three different closed states.

Gamal El-Din TM, Heldstab H, Lehmann C, Greeff NG.

Channels (Austin). 2010 Mar-Apr;4(2):93-100. Epub 2010 Mar 17.

PMID:
20009570
16.

More gating charges are needed to open a Shaker K+ channel than are needed to open an rBIIA Na+ channel.

Gamal El-Din TM, Grögler D, Lehmann C, Heldstab H, Greeff NG.

Biophys J. 2008 Aug;95(3):1165-75. doi: 10.1529/biophysj.108.130765. Epub 2008 Apr 4.

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