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Items: 30

1.

A 'poly-transfection' method for rapid, one-pot characterization and optimization of genetic systems.

Gam JJ, DiAndreth B, Jones RD, Huh J, Weiss R.

Nucleic Acids Res. 2019 Oct 10;47(18):e106. doi: 10.1093/nar/gkz623.

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A metal-free and mild approach to 1,3,4-oxadiazol-2(3H)-ones via oxidative C-C bond cleavage using molecular oxygen.

Lim B, Park S, Park JH, Gam J, Kim S, Yang JW, Lee J.

Org Biomol Chem. 2018 Mar 28;16(12):2105-2113. doi: 10.1039/c7ob03188b. Epub 2018 Mar 7.

PMID:
29511752
5.

Open-source, community-driven microfluidics with Metafluidics.

Kong DS, Thorsen TA, Babb J, Wick ST, Gam JJ, Weiss R, Carr PA.

Nat Biotechnol. 2017 Jun 7;35(6):523-529. doi: 10.1038/nbt.3873.

PMID:
28591125
6.

Highly Sensitive and Rapid Fluorescence Detection with a Portable FRET Analyzer.

Kim H, Han GH, Fu Y, Gam J, Lee SG.

J Vis Exp. 2016 Oct 1;(116). doi: 10.3791/54144.

7.

A critical element of the light-induced quaternary structural changes in YtvA-LOV.

Lee R, Gam J, Moon J, Lee SG, Suh YG, Lee BJ, Lee J.

Protein Sci. 2015 Dec;24(12):1997-2007. doi: 10.1002/pro.2810. Epub 2015 Oct 10.

8.

Ratiometric analyses at critical temperatures can magnify the signal intensity of FRET-based sugar sensors with periplasmic binding proteins.

Gam J, Ha JS, Kim H, Lee DH, Lee J, Lee SG.

Biosens Bioelectron. 2015 Oct 15;72:37-43. doi: 10.1016/j.bios.2015.04.083. Epub 2015 Apr 27.

PMID:
25957075
9.

Light-regulated tetracycline binding to the Tet repressor.

Moon J, Gam J, Lee SG, Suh YG, Lee J.

Chemistry. 2014 Feb 24;20(9):2508-14. doi: 10.1002/chem.201304027. Epub 2014 Jan 29.

PMID:
24478132
10.

Mapping protein-protein proximity in the purinosome.

Deng Y, Gam J, French JB, Zhao H, An S, Benkovic SJ.

J Biol Chem. 2012 Oct 19;287(43):36201-7. doi: 10.1074/jbc.M112.407056. Epub 2012 Sep 6.

11.

Polyvalent dendrimer-methotrexate as a folate receptor-targeted cancer therapeutic.

Thomas TP, Huang B, Choi SK, Silpe JE, Kotlyar A, Desai AM, Zong H, Gam J, Joice M, Baker JR Jr.

Mol Pharm. 2012 Sep 4;9(9):2669-2676. doi: 10.1021/mp3002232. Epub 2012 Aug 7.

12.

Quantitative analyses of individual sugars in mixture using FRET-based biosensors.

Ha JS, Gam J, Choi SL, Oh KH, Ro HS, Song JJ, Shin CS, Lee SG.

Biotechnol Prog. 2012 Sep-Oct;28(5):1376-83. doi: 10.1002/btpr.1592. Epub 2012 Jul 31.

PMID:
22753346
13.

Bifunctional PAMAM dendrimer conjugates of folic acid and methotrexate with defined ratio.

Zong H, Thomas TP, Lee KH, Desai AM, Li MH, Kotlyar A, Zhang Y, Leroueil PR, Gam JJ, Banaszak Holl MM, Baker JR Jr.

Biomacromolecules. 2012 Apr 9;13(4):982-91. doi: 10.1021/bm201639c. Epub 2012 Mar 30.

PMID:
22360561
14.

Biophysical characterization of a riboflavin-conjugated dendrimer platform for targeted drug delivery.

Witte AB, Timmer CM, Gam JJ, Choi SK, Banaszak Holl MM, Orr BG, Baker JR, Sinniah K.

Biomacromolecules. 2012 Feb 13;13(2):507-16. doi: 10.1021/bm201566g. Epub 2012 Jan 18.

15.

A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis.

Bhabha G, Lee J, Ekiert DC, Gam J, Wilson IA, Dyson HJ, Benkovic SJ, Wright PE.

Science. 2011 Apr 8;332(6026):234-8. doi: 10.1126/science.1198542.

16.

Kinetic and structural characterization of dihydrofolate reductase from Streptococcus pneumoniae.

Lee J, Yennawar NH, Gam J, Benkovic SJ.

Biochemistry. 2010 Jan 12;49(1):195-206. doi: 10.1021/bi901614m.

17.

Inhibition of HIV budding by a genetically selected cyclic peptide targeting the Gag-TSG101 interaction.

Tavassoli A, Lu Q, Gam J, Pan H, Benkovic SJ, Cohen SN.

ACS Chem Biol. 2008 Dec 19;3(12):757-64. doi: 10.1021/cb800193n.

PMID:
19053244
18.

Engineering of protease variants exhibiting high catalytic activity and exquisite substrate selectivity.

Varadarajan N, Gam J, Olsen MJ, Georgiou G, Iverson BL.

Proc Natl Acad Sci U S A. 2005 May 10;102(19):6855-60. Epub 2005 May 2.

19.

A periplasmic fluorescent reporter protein and its application in high-throughput membrane protein topology analysis.

Ki JJ, Kawarasaki Y, Gam J, Harvey BR, Iverson BL, Georgiou G.

J Mol Biol. 2004 Aug 20;341(4):901-9.

PMID:
15328603
20.

High-throughput FACS method for directed evolution of substrate specificity.

Olsen MJ, Gam J, Iverson BL, Georgiou G.

Methods Mol Biol. 2003;230:329-42. No abstract available.

PMID:
12824593
21.

Synthesis and anti-HIV-1 activity of a series of 1-alkoxy-5-alkyl-6-(arylthio)uracils.

Kim DK, Gam J, Kim YW, Lim J, Kim HT, Kim KH.

J Med Chem. 1997 Jul 18;40(15):2363-73.

PMID:
9240351
22.

Synthesis and antitumor activity of a series of [2-substituted-4,5-bis(aminomethyl)-1,3-dioxolane]platinum(II) complexes.

Kim DK, Kim G, Gam J, Cho YB, Kim HT, Tai JH, Kim KH, Hong WS, Park JG.

J Med Chem. 1994 May 13;37(10):1471-85.

PMID:
8182706
23.

[AIDS with apoplectic onset].

Gam J, Korbo L, Andersen J.

Ugeskr Laeger. 1994 Feb 28;156(9):1313-4. Danish.

PMID:
8009756
24.
25.

Thrombolytic therapy in acute ischemic stroke. A Danish pilot study.

Overgaard K, Sperling B, Boysen G, Pedersen H, Gam J, Ellemann K, Karle A, Arlien-Søborg P, Olsen TS, Videbaek C, et al.

Stroke. 1993 Oct;24(10):1439-46.

PMID:
8378943
26.

Alteplase therapy in acute ischemic stroke: a Danish pilot study.OFF.

Boysen G, Overgaard K, Sperling B, Pedersen H, Gam J, Ellemann K.

Z Kardiol. 1993;82 Suppl 2:105-8.

PMID:
8328185
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28.

[Delayed manifestations after acute oxygen deficiency in the cerebral white matter].

Gam J.

Ugeskr Laeger. 1987 Jun 22;149(26):1734-6. Danish. No abstract available.

PMID:
2885956
29.

[Reversible locked-in syndrome in hypoglycemia].

Gam J, Blichfeldt S.

Ugeskr Laeger. 1986 Feb 3;148(6):328-9. Danish. No abstract available.

PMID:
3952864
30.

[Accidents due to violence in Greenland].

Jørgensen B, Johansen LG, Roed S, Andersen JF, Nielsen F, Nielsen FK, Egelund B, Christensen R, Gam J, Baunsgård P, et al.

Ugeskr Laeger. 1984 Oct 29;146(44):3398-401. Danish. No abstract available.

PMID:
6506321

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