Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 159

1.

Biosafety Studies of a Clinically Applicable Lentiviral Vector for the Gene Therapy of Artemis-SCID.

Charrier S, Lagresle-Peyrou C, Poletti V, Rothe M, Cédrone G, Gjata B, Mavilio F, Fischer A, Schambach A, de Villartay JP, Cavazzana M, Hacein-Bey-Abina S, Galy A.

Mol Ther Methods Clin Dev. 2019 Sep 13;15:232-245. doi: 10.1016/j.omtm.2019.08.014. eCollection 2019 Dec 13.

2.

Sustained wood burial in the Bengal Fan over the last 19 My.

Lee H, Galy V, Feng X, Ponton C, Galy A, France-Lanord C, Feakins SJ.

Proc Natl Acad Sci U S A. 2019 Nov 5;116(45):22518-22525. doi: 10.1073/pnas.1913714116. Epub 2019 Oct 21.

PMID:
31636189
3.

Vectofusin-1 Improves Transduction of Primary Human Cells with Diverse Retroviral and Lentiviral Pseudotypes, Enabling Robust, Automated Closed-System Manufacturing.

Radek C, Bernadin O, Drechsel K, Cordes N, Pfeifer R, Sträßer P, Mormin M, Gutierrez-Guerrero A, Cosset FL, Kaiser AD, Schaser T, Galy A, Verhoeyen E, Johnston ICD.

Hum Gene Ther. 2019 Dec;30(12):1477-1493. doi: 10.1089/hum.2019.157. Epub 2019 Dec 3.

4.

Toward a Scalable Purification Protocol of GaLV-TR-Pseudotyped Lentiviral Vectors.

Boudeffa D, Bertin B, Biek A, Mormin M, Leseigneur F, Galy A, Merten OW.

Hum Gene Ther Methods. 2019 Oct;30(5):153-171. doi: 10.1089/hgtb.2019.076.

PMID:
31516018
5.

Successful engraftment of gene-corrected hematopoietic stem cells in non-conditioned patients with Fanconi anemia.

Río P, Navarro S, Wang W, Sánchez-Domínguez R, Pujol RM, Segovia JC, Bogliolo M, Merino E, Wu N, Salgado R, Lamana ML, Yañez RM, Casado JA, Giménez Y, Román-Rodríguez FJ, Álvarez L, Alberquilla O, Raimbault A, Guenechea G, Lozano ML, Cerrato L, Hernando M, Gálvez E, Hladun R, Giralt I, Barquinero J, Galy A, García de Andoín N, López R, Catalá A, Schwartz JD, Surrallés J, Soulier J, Schmidt M, Díaz de Heredia C, Sevilla J, Bueren JA.

Nat Med. 2019 Sep;25(9):1396-1401. doi: 10.1038/s41591-019-0550-z. Epub 2019 Sep 9.

PMID:
31501599
6.

Temporary Reduction of Membrane CD4 with the Antioxidant MnTBAP Is Sufficient to Prevent Immune Responses Induced by Gene Transfer.

Da Rocha S, Bigot J, Onodi F, Cosette J, Corre G, Poupiot J, Fenard D, Gjata B, Galy A, Neildez-Nguyen TMA.

Mol Ther Methods Clin Dev. 2019 Jul 23;14:285-299. doi: 10.1016/j.omtm.2019.06.011. eCollection 2019 Sep 13.

7.

Immune Response and Intraocular Inflammation in Patients With Leber Hereditary Optic Neuropathy Treated With Intravitreal Injection of Recombinant Adeno-Associated Virus 2 Carrying the ND4 Gene: A Secondary Analysis of a Phase 1/2 Clinical Trial.

Bouquet C, Vignal Clermont C, Galy A, Fitoussi S, Blouin L, Munk MR, Valero S, Meunier S, Katz B, Sahel JA, Thomasson N.

JAMA Ophthalmol. 2019 Apr 1;137(4):399-406. doi: 10.1001/jamaophthalmol.2018.6902.

8.

Effects of cone combinations on accurate and precise Mg-isotopic determination using multi-collector inductively coupled plasma mass spectrometry.

Gou LF, Jin Z, Galy A, Sun H, Deng L, Xu Y.

Rapid Commun Mass Spectrom. 2019 Feb 28;33(4):351-360. doi: 10.1002/rcm.8356.

PMID:
30447022
9.

Allogeneic stem cell transplantation recipients requiring intensive care: time is of the essence.

Orvain C, Beloncle F, Hamel JF, Del Galy AS, Thépot S, Mercier M, Kouatchet A, Farhi J, Francois S, Ifrah N, Mercat A, Asfar P, Hunault-Berger M, Tanguy-Schmidt A.

Ann Hematol. 2018 Sep;97(9):1601-1609. doi: 10.1007/s00277-018-3320-y. Epub 2018 May 2.

PMID:
29717367
10.

Non-Clinical Efficacy and Safety Studies on G1XCGD, a Lentiviral Vector for Ex Vivo Gene Therapy of X-Linked Chronic Granulomatous Disease.

Brendel C, Rothe M, Santilli G, Charrier S, Stein S, Kunkel H, Abriss D, Müller-Kuller U, Gaspar B, Modlich U, Galy A, Schambach A, Thrasher AJ, Grez M.

Hum Gene Ther Clin Dev. 2018 Jun;29(2):69-79. doi: 10.1089/humc.2017.245. Epub 2018 Apr 17.

PMID:
29664709
11.

Subretinal Injection of HY Peptides Induces Systemic Antigen-Specific Inhibition of Effector CD4+ and CD8+ T-Cell Responses.

Vendomèle J, Dehmani S, Khebizi Q, Galy A, Fisson S.

Front Immunol. 2018 Mar 13;9:504. doi: 10.3389/fimmu.2018.00504. eCollection 2018.

12.

[The plague: An overview and hot topics].

Galy A, Loubet P, Peiffer-Smadja N, Yazdanpanah Y.

Rev Med Interne. 2018 Nov;39(11):863-868. doi: 10.1016/j.revmed.2018.03.019. Epub 2018 Apr 5. Review. French.

PMID:
29628173
13.

Transitory microbial habitat in the hyperarid Atacama Desert.

Schulze-Makuch D, Wagner D, Kounaves SP, Mangelsdorf K, Devine KG, de Vera JP, Schmitt-Kopplin P, Grossart HP, Parro V, Kaupenjohann M, Galy A, Schneider B, Airo A, Frösler J, Davila AF, Arens FL, Cáceres L, Cornejo FS, Carrizo D, Dartnell L, DiRuggiero J, Flury M, Ganzert L, Gessner MO, Grathwohl P, Guan L, Heinz J, Hess M, Keppler F, Maus D, McKay CP, Meckenstock RU, Montgomery W, Oberlin EA, Probst AJ, Sáenz JS, Sattler T, Schirmack J, Sephton MA, Schloter M, Uhl J, Valenzuela B, Vestergaard G, Wörmer L, Zamorano P.

Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):2670-2675. doi: 10.1073/pnas.1714341115. Epub 2018 Feb 26.

14.

Implementation and evaluation of a therapeutic patient education programme during a clinical trial in Yaoundé, Cameroon - Trial ANRS-12286/MOBIDIP.

Galy A, Ciaffi L, Mberyo GM, Mbouyap P, Abessolo H, Toby R, Essomba F, Lamarre G, Bikié A, Bell O, Koulla-Shiro S, Delaporte E.

Patient Educ Couns. 2018 Jul;101(7):1262-1269. doi: 10.1016/j.pec.2018.01.021. Epub 2018 Feb 1.

PMID:
29433950
15.

Safety of rAAV2/2-ND4 Gene Therapy for Leber Hereditary Optic Neuropathy.

Vignal C, Uretsky S, Fitoussi S, Galy A, Blouin L, Girmens JF, Bidot S, Thomasson N, Bouquet C, Valero S, Meunier S, Combal JP, Gilly B, Katz B, Sahel JA.

Ophthalmology. 2018 Jun;125(6):945-947. doi: 10.1016/j.ophtha.2017.12.036. Epub 2018 Feb 14. No abstract available.

16.

Vectofusin-1, a potent peptidic enhancer of viral gene transfer forms pH-dependent α-helical nanofibrils, concentrating viral particles.

Vermeer LS, Hamon L, Schirer A, Schoup M, Cosette J, Majdoul S, Pastré D, Stockholm D, Holic N, Hellwig P, Galy A, Fenard D, Bechinger B.

Acta Biomater. 2017 Dec;64:259-268. doi: 10.1016/j.actbio.2017.10.009. Epub 2017 Oct 7.

PMID:
29017974
17.

Peptides derived from evolutionarily conserved domains in Beclin-1 and Beclin-2 enhance the entry of lentiviral vectors into human cells.

Majdoul S, Cosette J, Seye AK, Bernard E, Frin S, Holic N, Chazal N, Briant L, Espert L, Galy A, Fenard D.

J Biol Chem. 2017 Nov 10;292(45):18672-18681. doi: 10.1074/jbc.M117.800813. Epub 2017 Sep 19.

18.
19.

Engraftment and in vivo proliferation advantage of gene-corrected mobilized CD34+ cells from Fanconi anemia patients.

Río P, Navarro S, Guenechea G, Sánchez-Domínguez R, Lamana ML, Yañez R, Casado JA, Mehta PA, Pujol MR, Surrallés J, Charrier S, Galy A, Segovia JC, Díaz de Heredia C, Sevilla J, Bueren JA.

Blood. 2017 Sep 28;130(13):1535-1542. doi: 10.1182/blood-2017-03-774174. Epub 2017 Aug 11.

PMID:
28801449
20.

Gene therapy for Wiskott-Aldrich syndrome in a severely affected adult.

Morris EC, Fox T, Chakraverty R, Tendeiro R, Snell K, Rivat C, Grace S, Gilmour K, Workman S, Buckland K, Butler K, Chee R, Salama AD, Ibrahim H, Hara H, Duret C, Mavilio F, Male F, Bushman FD, Galy A, Burns SO, Gaspar HB, Thrasher AJ.

Blood. 2017 Sep 14;130(11):1327-1335. doi: 10.1182/blood-2017-04-777136. Epub 2017 Jul 17.

21.

Vectofusin-1 Promotes RD114-TR-Pseudotyped Lentiviral Vector Transduction of Human HSPCs and T Lymphocytes.

Piovan C, Marin V, Scavullo C, Corna S, Giuliani E, Bossi S, Galy A, Fenard D, Bordignon C, Rizzardi GP, Bovolenta C.

Mol Ther Methods Clin Dev. 2017 Mar 8;5:22-30. doi: 10.1016/j.omtm.2017.02.003. eCollection 2017 Jun 16.

22.

Improvement of De Novo Cholesterol Biosynthesis Efficiently Promotes the Production of Human Immunodeficiency Virus Type 1-Derived Lentiviral Vectors.

Holic N, Frin S, Seye AK, Galy A, Fenard D.

Hum Gene Ther Methods. 2017 Apr;28(2):67-77. doi: 10.1089/hgtb.2016.150. Epub 2016 Dec 29.

PMID:
28042946
23.

Simultaneous Analysis of Secondary Structure and Light Scattering from Circular Dichroism Titrations: Application to Vectofusin-1.

Vermeer LS, Marquette A, Schoup M, Fenard D, Galy A, Bechinger B.

Sci Rep. 2016 Dec 22;6:39450. doi: 10.1038/srep39450.

24.

Incidence of infectious morbidity events after second-line antiretroviral therapy initiation in HIV-infected adults in Yaoundé, Cameroon.

Galy A, Ciaffi L, Le Moing V, Eymard-Duvernay S, Abessolo H, Toby R, Ayangma L, Le Gac S, Mpoudi-Etame M, Koulla-Shiro S, Delaporte E, Cournil A; 2LADY Study Group.

Antivir Ther. 2016;21(6):547-552. doi: 10.3851/IMP3030. Epub 2016 Feb 16.

PMID:
26882335
25.

Like Angler Fish, CAARs Lure Their Prey.

Galy A.

Mol Ther. 2016 Aug;24(8):1339-41. doi: 10.1038/mt.2016.165. No abstract available.

26.

In Vivo Gene Delivery to Lymph Node Stromal Cells Leads to Transgene-specific CD8+ T Cell Anergy in Mice.

Ciré S, Da Rocha S, Ferrand M, Collins MK, Galy A.

Mol Ther. 2016 Nov;24(11):1965-1973. doi: 10.1038/mt.2016.168. Epub 2016 Aug 26.

27.

Twelfth Annual Meeting of the French Society of Cell and Gene Therapy.

Verhoeyen E, Gomez S, Galy A, Ayuso E, Midoux P, Pucéat M, Vassaux G, Cordelier P.

Hum Gene Ther. 2016 Jul;27(7):555-8. doi: 10.1089/hum.2016.29031.eve. No abstract available.

PMID:
27428658
28.

Systemic epigenetic response to recombinant lentiviral vectors independent of proviral integration.

Aranyi T, Stockholm D, Yao R, Poinsignon C, Wiart T, Corre G, Touleimat N, Tost J, Galy A, Paldi A.

Epigenetics Chromatin. 2016 Jul 11;9:29. doi: 10.1186/s13072-016-0077-1. eCollection 2016.

29.

Target-controlled inhalation anaesthesia: A cost-benefit analysis based on the cost per minute of anaesthesia by inhalation.

Ponsonnard S, Galy A, Cros J, Daragon AM, Nathan N.

Anaesth Crit Care Pain Med. 2017 Feb;36(1):33-37. doi: 10.1016/j.accpm.2016.02.005. Epub 2016 Jun 18.

PMID:
27329989
30.

Psoas abscess and chronic Q fever: a contiguous or hematogenous complication? A case report and literature review.

Galy A, Decousser JW, El-Anbassi S, Nebbad B, Belzunce C, Cochennec F, Deforges L, Lepeule R.

Infect Dis (Lond). 2016 Aug;48(8):626-31. doi: 10.1080/23744235.2016.1180709. Epub 2016 May 11.

PMID:
27167531
31.

Tertiary Lymphoid Organs in Takayasu Arteritis.

Clement M, Galy A, Bruneval P, Morvan M, Hyafil F, Benali K, Pasi N, Deschamps L, Pellenc Q, Papo T, Nicoletti A, Sacre K.

Front Immunol. 2016 Apr 22;7:158. doi: 10.3389/fimmu.2016.00158. eCollection 2016.

32.

Prognostic impact of left ventricular diastolic function in patients with septic shock.

Gonzalez C, Begot E, Dalmay F, Pichon N, François B, Fedou AL, Chapellas C, Galy A, Mancia C, Daix T, Vignon P.

Ann Intensive Care. 2016 Dec;6(1):36. doi: 10.1186/s13613-016-0136-6. Epub 2016 Apr 21.

33.

Presentation and impact of catheter-associated thrombosis in patients with infected long-term central venous catheters: a prospective bicentric observational study.

Galy A, Lepeule R, Goulenok T, Buzele R, de Lastours V, Fantin B.

Ann Med. 2016;48(3):182-9. doi: 10.3109/07853890.2016.1154981. Epub 2016 Mar 29.

PMID:
27022769
34.

"RCL-Pooling Assay": A Simplified Method for the Detection of Replication-Competent Lentiviruses in Vector Batches Using Sequential Pooling.

Corre G, Dessainte M, Marteau JB, Dalle B, Fenard D, Galy A.

Hum Gene Ther. 2016 Feb;27(2):202-10. doi: 10.1089/hum.2015.166.

PMID:
26886834
35.

Treatment of Uveitis by In Situ Administration of Ex Vivo-Activated Polyclonal Regulatory T Cells.

Grégoire S, Terrada C, Martin GH, Fourcade G, Baeyens A, Marodon G, Fisson S, Billiard F, Lucas B, Tadayoni R, Béhar-Cohen F, Levacher B, Galy A, LeHoang P, Klatzmann D, Bodaghi B, Salomon BL.

J Immunol. 2016 Mar 1;196(5):2109-18. doi: 10.4049/jimmunol.1501723. Epub 2016 Jan 29.

36.

[Efficacy and safety of gene therapy for Wiskott-Aldrich syndrome].

Galy A, Corre G, Cavazzana M, Hacein-Bey-Abina S.

Med Sci (Paris). 2015 Dec;31(12):1066-9. doi: 10.1051/medsci/20153112006. Epub 2015 Dec 16. French. No abstract available.

37.

Molecular Determinants of Vectofusin-1 and Its Derivatives for the Enhancement of Lentivirally Mediated Gene Transfer into Hematopoietic Stem/Progenitor Cells.

Majdoul S, Seye AK, Kichler A, Holic N, Galy A, Bechinger B, Fenard D.

J Biol Chem. 2016 Jan 29;291(5):2161-9. doi: 10.1074/jbc.M115.675033. Epub 2015 Dec 14.

38.

Lentiviral-Mediated Gene Therapy in Fanconi Anemia-A Mice Reveals Long-Term Engraftment and Continuous Turnover of Corrected HSCs.

Molina-Estevez FJ, Nowrouzi A, Lozano ML, Galy A, Charrier S, von Kalle C, Guenechea G, Bueren JA, Schmidt M.

Curr Gene Ther. 2015;15(6):550-62.

PMID:
26415575
39.

Lymphopoiesis in transgenic mice over-expressing Artemis.

Rivera-Munoz P, Abramowski V, Jacquot S, André P, Charrier S, Lipson-Ruffert K, Fischer A, Galy A, Cavazzana M, de Villartay JP.

Gene Ther. 2016 Feb;23(2):176-86. doi: 10.1038/gt.2015.95. Epub 2015 Oct 1.

PMID:
26361272
40.

Outcomes following gene therapy in patients with severe Wiskott-Aldrich syndrome.

Hacein-Bey Abina S, Gaspar HB, Blondeau J, Caccavelli L, Charrier S, Buckland K, Picard C, Six E, Himoudi N, Gilmour K, McNicol AM, Hara H, Xu-Bayford J, Rivat C, Touzot F, Mavilio F, Lim A, Treluyer JM, Héritier S, Lefrère F, Magalon J, Pengue-Koyi I, Honnet G, Blanche S, Sherman EA, Male F, Berry C, Malani N, Bushman FD, Fischer A, Thrasher AJ, Galy A, Cavazzana M.

JAMA. 2015 Apr 21;313(15):1550-63. doi: 10.1001/jama.2015.3253.

41.

Serotype-specific Binding Properties and Nanoparticle Characteristics Contribute to the Immunogenicity of rAAV1 Vectors.

Ferrand M, Da Rocha S, Corre G, Galy A, Boisgerault F.

Mol Ther. 2015 Jun;23(6):1022-1033. doi: 10.1038/mt.2015.59. Epub 2015 Apr 16.

42.

Hypoxic culture conditions enhance the generation of regulatory T cells.

Neildez-Nguyen TMA, Bigot J, Da Rocha S, Corre G, Boisgerault F, Paldi A, Galy A.

Immunology. 2015 Mar;144(3):431-443. doi: 10.1111/imm.12388.

43.

Influence of mildly acidic pH conditions on the production of lentiviral and retroviral vectors.

Holic N, Seye AK, Majdoul S, Martin S, Merten OW, Galy A, Fenard D.

Hum Gene Ther Clin Dev. 2014 Sep;25(3):178-85. doi: 10.1089/humc.2014.027. Epub 2014 Sep 5.

44.

Immunization of mice with lentiviral vectors targeted to MHC class II+ cells is due to preferential transduction of dendritic cells in vivo.

Ciré S, Da Rocha S, Yao R, Fisson S, Buchholz CJ, Collins MK, Galy A.

PLoS One. 2014 Jul 24;9(7):e101644. doi: 10.1371/journal.pone.0101644. eCollection 2014.

45.

A dystrophic muscle broadens the contribution and activation of immune cells reacting to rAAV gene transfer.

Ferrand M, Galy A, Boisgerault F.

Gene Ther. 2014 Sep;21(9):828-39. doi: 10.1038/gt.2014.61. Epub 2014 Jul 17.

46.

Human intellectual disability genes form conserved functional modules in Drosophila.

Oortveld MA, Keerthikumar S, Oti M, Nijhof B, Fernandes AC, Kochinke K, Castells-Nobau A, van Engelen E, Ellenkamp T, Eshuis L, Galy A, van Bokhoven H, Habermann B, Brunner HG, Zweier C, Verstreken P, Huynen MA, Schenck A.

PLoS Genet. 2013 Oct;9(10):e1003911. doi: 10.1371/journal.pgen.1003911. Epub 2013 Oct 31.

47.

Concurrent measures of fusion and transduction efficiency of primary CD34+ cells with human immunodeficiency virus 1-based lentiviral vectors reveal different effects of transduction enhancers.

Ingrao D, Majdoul S, Seye AK, Galy A, Fenard D.

Hum Gene Ther Methods. 2014 Feb;25(1):48-56. doi: 10.1089/hgtb.2013.090. Epub 2013 Nov 20.

48.

Gene therapy on the move.

Kaufmann KB, Büning H, Galy A, Schambach A, Grez M.

EMBO Mol Med. 2013 Nov;5(11):1642-61. doi: 10.1002/emmm.201202287. Epub 2013 Sep 17. Review.

49.

Heterozygous and homozygous JAK2(V617F) states modeled by induced pluripotent stem cells from myeloproliferative neoplasm patients.

Saliba J, Hamidi S, Lenglet G, Langlois T, Yin J, Cabagnols X, Secardin L, Legrand C, Galy A, Opolon P, Benyahia B, Solary E, Bernard OA, Chen L, Debili N, Raslova H, Norol F, Vainchenker W, Plo I, Di Stefano A.

PLoS One. 2013 Sep 16;8(9):e74257. doi: 10.1371/journal.pone.0074257. eCollection 2013.

50.

Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome.

Aiuti A, Biasco L, Scaramuzza S, Ferrua F, Cicalese MP, Baricordi C, Dionisio F, Calabria A, Giannelli S, Castiello MC, Bosticardo M, Evangelio C, Assanelli A, Casiraghi M, Di Nunzio S, Callegaro L, Benati C, Rizzardi P, Pellin D, Di Serio C, Schmidt M, Von Kalle C, Gardner J, Mehta N, Neduva V, Dow DJ, Galy A, Miniero R, Finocchi A, Metin A, Banerjee PP, Orange JS, Galimberti S, Valsecchi MG, Biffi A, Montini E, Villa A, Ciceri F, Roncarolo MG, Naldini L.

Science. 2013 Aug 23;341(6148):1233151. doi: 10.1126/science.1233151. Epub 2013 Jul 11.

Supplemental Content

Support Center