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Items: 39

1.

Monitoring real-time hormone release kinetics via high-content 3-D imaging of compensatory endocytosis.

Tarasov AI, Galvanovskis J, Rorsman O, Hamilton A, Vergari E, Johnson PRV, Reimann F, Ashcroft FM, Rorsman P.

Lab Chip. 2018 Sep 11;18(18):2838-2848. doi: 10.1039/c8lc00417j.

2.

Increased Expression of the Diabetes Gene SOX4 Reduces Insulin Secretion by Impaired Fusion Pore Expansion.

Collins SC, Do HW, Hastoy B, Hugill A, Adam J, Chibalina MV, Galvanovskis J, Godazgar M, Lee S, Goldsworthy M, Salehi A, Tarasov AI, Rosengren AH, Cox R, Rorsman P.

Diabetes. 2016 Jul;65(7):1952-61. doi: 10.2337/db15-1489. Epub 2016 Mar 18.

3.

Water intake disorder in a DEND syndrome afflicted patient with R50P mutation.

Maejima Y, Hasegawa S, Horita S, Kumamoto K, Galvanovskis J, Takenoshita S, Shimomura K.

Endocr J. 2015;62(4):387-92. doi: 10.1507/endocrj.EJ14-0392. Epub 2015 Mar 14.

4.

Role of KATP channels in glucose-regulated glucagon secretion and impaired counterregulation in type 2 diabetes.

Zhang Q, Ramracheya R, Lahmann C, Tarasov A, Bengtsson M, Braha O, Braun M, Brereton M, Collins S, Galvanovskis J, Gonzalez A, Groschner LN, Rorsman NJ, Salehi A, Travers ME, Walker JN, Gloyn AL, Gribble F, Johnson PR, Reimann F, Ashcroft FM, Rorsman P.

Cell Metab. 2013 Dec 3;18(6):871-82. doi: 10.1016/j.cmet.2013.10.014.

5.

Bupropion can close KATP channel and induce insulin secretion.

Yang Y, Shimomura K, Sakuma K, Maejima Y, Iwasaki Y, Galvanovskis J, Dezaki K, Nakata M, Yada T.

J Pediatr Endocrinol Metab. 2013;26(3-4):343-6. doi: 10.1515/jpem-2012-0295.

PMID:
23348218
6.

Exocytosis from pancreatic β-cells: mathematical modelling of the exit of low-molecular-weight granule content.

Galvanovskis J, Braun M, Rorsman P.

Interface Focus. 2011 Feb 6;1(1):143-52. doi: 10.1098/rsfs.2010.0006. Epub 2010 Dec 8.

7.

Multivesicular exocytosis in rat pancreatic beta cells.

Hoppa MB, Jones E, Karanauskaite J, Ramracheya R, Braun M, Collins SC, Zhang Q, Clark A, Eliasson L, Genoud C, Macdonald PE, Monteith AG, Barg S, Galvanovskis J, Rorsman P.

Diabetologia. 2012 Apr;55(4):1001-12. doi: 10.1007/s00125-011-2400-5. Epub 2011 Dec 22.

8.

SEDLIN forms homodimers: characterisation of SEDLIN mutations and their interactions with transcription factors MBP1, PITX1 and SF1.

Jeyabalan J, Nesbit MA, Galvanovskis J, Callaghan R, Rorsman P, Thakker RV.

PLoS One. 2010 May 14;5(5):e10646. doi: 10.1371/journal.pone.0010646.

9.

CLC-5 and KIF3B interact to facilitate CLC-5 plasma membrane expression, endocytosis, and microtubular transport: relevance to pathophysiology of Dent's disease.

Reed AA, Loh NY, Terryn S, Lippiat JD, Partridge C, Galvanovskis J, Williams SE, Jouret F, Wu FT, Courtoy PJ, Nesbit MA, Rorsman P, Devuyst O, Ashcroft FM, Thakker RV.

Am J Physiol Renal Physiol. 2010 Feb;298(2):F365-80. doi: 10.1152/ajprenal.00038.2009. Epub 2009 Nov 25.

10.

Uromodulin mutations causing familial juvenile hyperuricaemic nephropathy lead to protein maturation defects and retention in the endoplasmic reticulum.

Williams SE, Reed AA, Galvanovskis J, Antignac C, Goodship T, Karet FE, Kotanko P, Lhotta K, Morinière V, Williams P, Wong W, Rorsman P, Thakker RV.

Hum Mol Genet. 2009 Aug 15;18(16):2963-74. doi: 10.1093/hmg/ddp235. Epub 2009 May 22.

11.

Insulin secretion from beta-cells is affected by deletion of nicotinamide nucleotide transhydrogenase.

Shimomura K, Galvanovskis J, Goldsworthy M, Hugill A, Kaizak S, Lee A, Meadows N, Quwailid MM, Rydström J, Teboul L, Ashcroft F, Cox RD.

Methods Enzymol. 2009;457:451-80. doi: 10.1016/S0076-6879(09)05025-3.

12.

Impaired insulin exocytosis in neural cell adhesion molecule-/- mice due to defective reorganization of the submembrane F-actin network.

Olofsson CS, Håkansson J, Salehi A, Bengtsson M, Galvanovskis J, Partridge C, SörhedeWinzell M, Xian X, Eliasson L, Lundquist I, Semb H, Rorsman P.

Endocrinology. 2009 Jul;150(7):3067-75. doi: 10.1210/en.2008-0475. Epub 2009 Feb 12.

13.

Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic beta cells recapitulates neonatal diabetes.

Girard CA, Wunderlich FT, Shimomura K, Collins S, Kaizik S, Proks P, Abdulkader F, Clark A, Ball V, Zubcevic L, Bentley L, Clark R, Church C, Hugill A, Galvanovskis J, Cox R, Rorsman P, Brüning JC, Ashcroft FM.

J Clin Invest. 2009 Jan;119(1):80-90. doi: 10.1172/JCI35772. Epub 2008 Dec 8.

14.

PVHL is a regulator of glucose metabolism and insulin secretion in pancreatic beta cells.

Zehetner J, Danzer C, Collins S, Eckhardt K, Gerber PA, Ballschmieter P, Galvanovskis J, Shimomura K, Ashcroft FM, Thorens B, Rorsman P, Krek W.

Genes Dev. 2008 Nov 15;22(22):3135-46. doi: 10.1101/gad.496908.

15.

Quantal ATP release in rat beta-cells by exocytosis of insulin-containing LDCVs.

Karanauskaite J, Hoppa MB, Braun M, Galvanovskis J, Rorsman P.

Pflugers Arch. 2009 Jun;458(2):389-401. doi: 10.1007/s00424-008-0610-6. Epub 2008 Nov 19.

PMID:
19018564
16.

Kiss-and-run exocytosis and fusion pores of secretory vesicles in human beta-cells.

Hanna ST, Pigeau GM, Galvanovskis J, Clark A, Rorsman P, MacDonald PE.

Pflugers Arch. 2009 Apr;457(6):1343-50. doi: 10.1007/s00424-008-0588-0. Epub 2008 Sep 16.

PMID:
18795319
17.

Cell coupling in mouse pancreatic beta-cells measured in intact islets of Langerhans.

Zhang Q, Galvanovskis J, Abdulkader F, Partridge CJ, Göpel SO, Eliasson L, Rorsman P.

Philos Trans A Math Phys Eng Sci. 2008 Oct 13;366(1880):3503-23. doi: 10.1098/rsta.2008.0110.

PMID:
18632454
18.

Novel aspects of the molecular mechanisms controlling insulin secretion.

Eliasson L, Abdulkader F, Braun M, Galvanovskis J, Hoppa MB, Rorsman P.

J Physiol. 2008 Jul 15;586(14):3313-24. doi: 10.1113/jphysiol.2008.155317. Epub 2008 May 29. Review.

19.

Palmitate-induced beta-cell dysfunction is associated with excessive NO production and is reversed by thiazolidinedione-mediated inhibition of GPR40 transduction mechanisms.

Meidute Abaraviciene S, Lundquist I, Galvanovskis J, Flodgren E, Olde B, Salehi A.

PLoS One. 2008 May 14;3(5):e2182. doi: 10.1371/journal.pone.0002182. Erratum in: PLoS ONE. 2008;3(5). doi: 10.1371/annotation/21d1a1f6-35e9-4935-a8d0-387c057f1469. PLoS ONE. 2008;3(5). doi: 10.1371/annotation/682082fc-c500-414b-9f57-f9420c00c57e.

20.

The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase.

Gerken T, Girard CA, Tung YC, Webby CJ, Saudek V, Hewitson KS, Yeo GS, McDonough MA, Cunliffe S, McNeill LA, Galvanovskis J, Rorsman P, Robins P, Prieur X, Coll AP, Ma M, Jovanovic Z, Farooqi IS, Sedgwick B, Barroso I, Lindahl T, Ponting CP, Ashcroft FM, O'Rahilly S, Schofield CJ.

Science. 2007 Nov 30;318(5855):1469-72. Epub 2007 Nov 8.

21.

Corelease and differential exit via the fusion pore of GABA, serotonin, and ATP from LDCV in rat pancreatic beta cells.

Braun M, Wendt A, Karanauskaite J, Galvanovskis J, Clark A, MacDonald PE, Rorsman P.

J Gen Physiol. 2007 Mar;129(3):221-31. Epub 2007 Feb 12.

22.

Release of small transmitters through kiss-and-run fusion pores in rat pancreatic beta cells.

MacDonald PE, Braun M, Galvanovskis J, Rorsman P.

Cell Metab. 2006 Oct;4(4):283-90.

23.

Selective nucleotide-release from dense-core granules in insulin-secreting cells.

Obermüller S, Lindqvist A, Karanauskaite J, Galvanovskis J, Rorsman P, Barg S.

J Cell Sci. 2005 Sep 15;118(Pt 18):4271-82. Epub 2005 Sep 1.

24.

Regulated exocytosis and kiss-and-run of synaptic-like microvesicles in INS-1 and primary rat beta-cells.

MacDonald PE, Obermüller S, Vikman J, Galvanovskis J, Rorsman P, Eliasson L.

Diabetes. 2005 Mar;54(3):736-43.

25.

Temperature-sensitive random insulin granule diffusion is a prerequisite for recruiting granules for release.

Ivarsson R, Obermüller S, Rutter GA, Galvanovskis J, Renström E.

Traffic. 2004 Oct;5(10):750-62.

26.

Large dense-core vesicle exocytosis in pancreatic beta-cells monitored by capacitance measurements.

Kanno T, Ma X, Barg S, Eliasson L, Galvanovskis J, Göpel S, Larsson M, Renström E, Rorsman P.

Methods. 2004 Aug;33(4):302-11.

PMID:
15183179
27.

Capacitance measurements of exocytosis in mouse pancreatic alpha-, beta- and delta-cells within intact islets of Langerhans.

Göpel S, Zhang Q, Eliasson L, Ma XS, Galvanovskis J, Kanno T, Salehi A, Rorsman P.

J Physiol. 2004 May 1;556(Pt 3):711-26. Epub 2004 Feb 13.

28.

Regulated exocytosis of GABA-containing synaptic-like microvesicles in pancreatic beta-cells.

Braun M, Wendt A, Birnir B, Broman J, Eliasson L, Galvanovskis J, Gromada J, Mulder H, Rorsman P.

J Gen Physiol. 2004 Mar;123(3):191-204. Epub 2004 Feb 9.

29.

SUR1 regulates PKA-independent cAMP-induced granule priming in mouse pancreatic B-cells.

Eliasson L, Ma X, Renström E, Barg S, Berggren PO, Galvanovskis J, Gromada J, Jing X, Lundquist I, Salehi A, Sewing S, Rorsman P.

J Gen Physiol. 2003 Mar;121(3):181-97.

30.

Fast insulin secretion reflects exocytosis of docked granules in mouse pancreatic B-cells.

Olofsson CS, Göpel SO, Barg S, Galvanovskis J, Ma X, Salehi A, Rorsman P, Eliasson L.

Pflugers Arch. 2002 May;444(1-2):43-51. Epub 2002 Jan 31.

PMID:
11976915
31.

Fast exocytosis with few Ca(2+) channels in insulin-secreting mouse pancreatic B cells.

Barg S, Ma X, Eliasson L, Galvanovskis J, Göpel SO, Obermüller S, Platzer J, Renström E, Trus M, Atlas D, Striessnig J, Rorsman P.

Biophys J. 2001 Dec;81(6):3308-23.

32.

Voltage-dependent formation of gramicidin channels in lipid bilayers.

Sandblom J, Galvanovskis J, Jilderos B.

Biophys J. 2001 Aug;81(2):827-37.

33.

Tight coupling between electrical activity and exocytosis in mouse glucagon-secreting alpha-cells.

Barg S, Galvanovskis J, Göpel SO, Rorsman P, Eliasson L.

Diabetes. 2000 Sep;49(9):1500-10.

PMID:
10969834
34.

Voltage-gated and resting membrane currents recorded from B-cells in intact mouse pancreatic islets.

Göpel S, Kanno T, Barg S, Galvanovskis J, Rorsman P.

J Physiol. 1999 Dec 15;521 Pt 3:717-28.

35.

Activation of Ca(2+)-dependent K(+) channels contributes to rhythmic firing of action potentials in mouse pancreatic beta cells.

Göpel SO, Kanno T, Barg S, Eliasson L, Galvanovskis J, Renström E, Rorsman P.

J Gen Physiol. 1999 Dec;114(6):759-70.

36.

Cytoplasmic Ca2+ oscillations in human leukemia T-cells are reduced by 50 Hz magnetic fields.

Galvanovskis J, Sandblom J, Bergqvist B, Galt S, Hamnerius Y.

Bioelectromagnetics. 1999;20(5):269-76.

PMID:
10407511
37.

Amplification of electromagnetic signals by ion channels.

Galvanovskis J, Sandblom J.

Biophys J. 1997 Dec;73(6):3056-65.

38.

The influence of 50-Hz magnetic fields on cytoplasmic Ca2+ oscillations in human leukemia T-cells.

Galvanovskis J, Sandblom J, Bergqvist B, Galt S, Hamnerius Y.

Sci Total Environ. 1996 Feb 2;180(1):19-33.

PMID:
8717317
39.

The frequency response of ion channel currents in a combined diffusion and barrier type model.

Sandblom J, George P, Galvanovskis J.

J Theor Biol. 1995 Sep 7;176(1):153-60.

PMID:
7475098

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