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Items: 1 to 50 of 81

1.

Exploring porosity in ceramics at nm scale using Small-Angle Neutron Scattering: from an understanding of historical ceramics towards the design of novel innovative materials.

Mondelli C, Zorzi S, Ricci G, Galvan V, Balliana E, Schweins R, Cattaruzza E.

Chemphyschem. 2020 Apr 1. doi: 10.1002/cphc.202000088. [Epub ahead of print]

PMID:
32237264
2.

mTOR drives cerebrovascular, synaptic, and cognitive dysfunction in normative aging.

Van Skike CE, Lin AL, Roberts Burbank R, Halloran JJ, Hernandez SF, Cuvillier J, Soto VY, Hussong SA, Jahrling JB, Javors MA, Hart MJ, Fischer KE, Austad SN, Galvan V.

Aging Cell. 2020 Jan;19(1):e13057. doi: 10.1111/acel.13057. Epub 2019 Nov 6.

3.

mTOR in cerebrovascular disease.

Van Skike CE, Galvan V.

Aging (Albany NY). 2019 Mar 13;11(5):1331-1332. doi: 10.18632/aging.101869. No abstract available.

4.

Rapamycin and Alzheimer's disease: Time for a clinical trial?

Kaeberlein M, Galvan V.

Sci Transl Med. 2019 Jan 23;11(476). pii: eaar4289. doi: 10.1126/scitranslmed.aar4289. Review.

5.

Mechanisms of Vascular Aging.

Ungvari Z, Tarantini S, Donato AJ, Galvan V, Csiszar A.

Circ Res. 2018 Sep 14;123(7):849-867. doi: 10.1161/CIRCRESAHA.118.311378. Review.

6.

A Carbon-Neutral CO2 Capture, Conversion, and Utilization Cycle with Low-Temperature Regeneration of Sodium Hydroxide.

Kar S, Goeppert A, Galvan V, Chowdhury R, Olah J, Prakash GKS.

J Am Chem Soc. 2018 Dec 12;140(49):16873-16876. doi: 10.1021/jacs.8b09325. Epub 2018 Oct 19.

PMID:
30339394
7.

Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive Decline.

Valcarcel-Ares MN, Tucsek Z, Kiss T, Giles CB, Tarantini S, Yabluchanskiy A, Balasubramanian P, Gautam T, Galvan V, Ballabh P, Richardson A, Freeman WM, Wren JD, Deak F, Ungvari Z, Csiszar A.

J Gerontol A Biol Sci Med Sci. 2019 Feb 15;74(3):290-298. doi: 10.1093/gerona/gly127.

8.

Hydrogen sulfide ameliorates aging-associated changes in the kidney.

Lee HJ, Feliers D, Barnes JL, Oh S, Choudhury GG, Diaz V, Galvan V, Strong R, Nelson J, Salmon A, Kevil CG, Kasinath BS.

Geroscience. 2018 Apr;40(2):163-176. doi: 10.1007/s11357-018-0018-y. Epub 2018 May 1.

9.

Inborn Errors of RNA Lariat Metabolism in Humans with Brainstem Viral Infection.

Zhang SY, Clark NE, Freije CA, Pauwels E, Taggart AJ, Okada S, Mandel H, Garcia P, Ciancanelli MJ, Biran A, Lafaille FG, Tsumura M, Cobat A, Luo J, Volpi S, Zimmer B, Sakata S, Dinis A, Ohara O, Garcia Reino EJ, Dobbs K, Hasek M, Holloway SP, McCammon K, Hussong SA, DeRosa N, Van Skike CE, Katolik A, Lorenzo L, Hyodo M, Faria E, Halwani R, Fukuhara R, Smith GA, Galvan V, Damha MJ, Al-Muhsen S, Itan Y, Boeke JD, Notarangelo LD, Studer L, Kobayashi M, Diogo L, Fairbrother WG, Abel L, Rosenberg BR, Hart PJ, Etzioni A, Casanova JL.

Cell. 2018 Feb 22;172(5):952-965.e18. doi: 10.1016/j.cell.2018.02.019.

10.

Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer's disease and vascular cognitive impairment.

Van Skike CE, Jahrling JB, Olson AB, Sayre NL, Hussong SA, Ungvari Z, Lechleiter JD, Galvan V.

Am J Physiol Heart Circ Physiol. 2018 Apr 1;314(4):H693-H703. doi: 10.1152/ajpheart.00570.2017. Epub 2017 Dec 22.

11.

A Perfect sTORm: The Role of the Mammalian Target of Rapamycin (mTOR) in Cerebrovascular Dysfunction of Alzheimer's Disease: A Mini-Review.

Van Skike CE, Galvan V.

Gerontology. 2018;64(3):205-211. doi: 10.1159/000485381. Epub 2018 Jan 11. Review.

12.

Genomic patterns in Acropora cervicornis show extensive population structure and variable genetic diversity.

Drury C, Schopmeyer S, Goergen E, Bartels E, Nedimyer K, Johnson M, Maxwell K, Galvan V, Manfrino C, Lirman D.

Ecol Evol. 2017 Jun 30;7(16):6188-6200. doi: 10.1002/ece3.3184. eCollection 2017 Aug.

13.

Hypertension impairs neurovascular coupling and promotes microvascular injury: role in exacerbation of Alzheimer's disease.

Csiszar A, Tarantini S, Fülöp GA, Kiss T, Valcarcel-Ares MN, Galvan V, Ungvari Z, Yabluchanskiy A.

Geroscience. 2017 Aug;39(4):359-372. doi: 10.1007/s11357-017-9991-9. Epub 2017 Aug 29.

14.

Age-related impairment of metabovascular coupling during cortical spreading depolarizations.

Marinesco S, Ungvari Z, Galvan V.

Am J Physiol Heart Circ Physiol. 2017 Dec 1;313(6):H1209-H1212. doi: 10.1152/ajpheart.00514.2017. Epub 2017 Aug 25. No abstract available.

15.

An Inexpensive Paper-Based Aluminum-Air Battery.

Avoundjian A, Galvan V, Gomez FA.

Micromachines (Basel). 2017 Jul 17;8(7). pii: E222. doi: 10.3390/mi8070222.

16.

Cerebral Microvascular Accumulation of Tau Oligomers in Alzheimer's Disease and Related Tauopathies.

Castillo-Carranza DL, Nilson AN, Van Skike CE, Jahrling JB, Patel K, Garach P, Gerson JE, Sengupta U, Abisambra J, Nelson P, Troncoso J, Ungvari Z, Galvan V, Kayed R.

Aging Dis. 2017 May 2;8(3):257-266. doi: 10.14336/AD.2017.0112. eCollection 2017 May.

17.

Demonstration of impaired neurovascular coupling responses in TG2576 mouse model of Alzheimer's disease using functional laser speckle contrast imaging.

Tarantini S, Fulop GA, Kiss T, Farkas E, Zölei-Szénási D, Galvan V, Toth P, Csiszar A, Ungvari Z, Yabluchanskiy A.

Geroscience. 2017 Aug;39(4):465-473. doi: 10.1007/s11357-017-9980-z. Epub 2017 Jun 3.

18.

mTOR drives cerebral blood flow and memory deficits in LDLR-/- mice modeling atherosclerosis and vascular cognitive impairment.

Jahrling JB, Lin AL, DeRosa N, Hussong SA, Van Skike CE, Girotti M, Javors M, Zhao Q, Maslin LA, Asmis R, Galvan V.

J Cereb Blood Flow Metab. 2018 Jan;38(1):58-74. doi: 10.1177/0271678X17705973. Epub 2017 May 17.

19.

Polyphosphate: A Conserved Modifier of Amyloidogenic Processes.

Cremers CM, Knoefler D, Gates S, Martin N, Dahl JU, Lempart J, Xie L, Chapman MR, Galvan V, Southworth DR, Jakob U.

Mol Cell. 2016 Sep 1;63(5):768-80. doi: 10.1016/j.molcel.2016.07.016. Epub 2016 Aug 25.

20.

Netrin-1 Interrupts Amyloid-β Amplification, Increases sAβPPα in vitro and in vivo, and Improves Cognition in a Mouse Model of Alzheimer's Disease.

Spilman PR, Corset V, Gorostiza O, Poksay KS, Galvan V, Zhang J, Rao R, Peters-Libeu C, Vincelette J, McGeehan A, Dvorak-Ewell M, Beyer J, Campagna J, Bankiewicz K, Mehlen P, John V, Bredesen DE.

J Alzheimers Dis. 2016 Mar 8;52(1):223-42. doi: 10.3233/JAD-151046.

PMID:
27060954
21.

Rapamycin rescues vascular, metabolic and learning deficits in apolipoprotein E4 transgenic mice with pre-symptomatic Alzheimer's disease.

Lin AL, Jahrling JB, Zhang W, DeRosa N, Bakshi V, Romero P, Galvan V, Richardson A.

J Cereb Blood Flow Metab. 2017 Jan;37(1):217-226. Epub 2015 Dec 31.

22.

Vascular mTOR-dependent mechanisms linking the control of aging to Alzheimer's disease.

Galvan V, Hart MJ.

Biochim Biophys Acta. 2016 May;1862(5):992-1007. doi: 10.1016/j.bbadis.2015.11.010. Epub 2015 Nov 27. Review.

23.

An improved alkaline direct formate paper microfluidic fuel cell.

Galvan V, Domalaon K, Tang C, Sotez S, Mendez A, Jalali-Heravi M, Purohit K, Pham L, Haan J, Gomez FA.

Electrophoresis. 2016 Feb;37(3):504-10. doi: 10.1002/elps.201500360. Epub 2015 Dec 15.

PMID:
26572774
24.

Chronic mTOR inhibition in mice with rapamycin alters T, B, myeloid, and innate lymphoid cells and gut flora and prolongs life of immune-deficient mice.

Hurez V, Dao V, Liu A, Pandeswara S, Gelfond J, Sun L, Bergman M, Orihuela CJ, Galvan V, Padrón Á, Drerup J, Liu Y, Hasty P, Sharp ZD, Curiel TJ.

Aging Cell. 2015 Dec;14(6):945-56. doi: 10.1111/acel.12380. Epub 2015 Aug 28.

25.

Glial alterations from early to late stages in a model of Alzheimer's disease: Evidence of autophagy involvement in Aβ internalization.

Pomilio C, Pavia P, Gorojod RM, Vinuesa A, Alaimo A, Galvan V, Kotler ML, Beauquis J, Saravia F.

Hippocampus. 2016 Feb;26(2):194-210. doi: 10.1002/hipo.22503. Epub 2015 Sep 4.

26.

A microfluidic direct formate fuel cell on paper.

Copenhaver TS, Purohit KH, Domalaon K, Pham L, Burgess BJ, Manorothkul N, Galvan V, Sotez S, Gomez FA, Haan JL.

Electrophoresis. 2015 Aug;36(16):1825-9. doi: 10.1002/elps.201400554. Epub 2015 Mar 12.

PMID:
25546700
27.

How longevity research can lead to therapies for Alzheimer's disease: The rapamycin story.

Richardson A, Galvan V, Lin AL, Oddo S.

Exp Gerontol. 2015 Aug;68:51-8. doi: 10.1016/j.exger.2014.12.002. Epub 2014 Dec 3. Review.

28.

Divergent tissue and sex effects of rapamycin on the proteasome-chaperone network of old mice.

Rodriguez KA, Dodds SG, Strong R, Galvan V, Sharp ZD, Buffenstein R.

Front Mol Neurosci. 2014 Nov 4;7:83. doi: 10.3389/fnmol.2014.00083. eCollection 2014.

29.

Growth dynamics of the threatened Caribbean staghorn coral Acropora cervicornis: influence of host genotype, symbiont identity, colony size, and environmental setting.

Lirman D, Schopmeyer S, Galvan V, Drury C, Baker AC, Baums IB.

PLoS One. 2014 Sep 30;9(9):e107253. doi: 10.1371/journal.pone.0107253. eCollection 2014.

30.

Neuronal and glial alterations, increased anxiety, and cognitive impairment before hippocampal amyloid deposition in PDAPP mice, model of Alzheimer's disease.

Beauquis J, Vinuesa A, Pomilio C, Pavía P, Galván V, Saravia F.

Hippocampus. 2014 Mar;24(3):257-69. doi: 10.1002/hipo.22219. Epub 2013 Nov 12.

PMID:
24132937
31.

Differential activation of mTOR complex 1 signaling in human brain with mild to severe Alzheimer's disease.

Sun YX, Ji X, Mao X, Xie L, Jia J, Galvan V, Greenberg DA, Jin K.

J Alzheimers Dis. 2014;38(2):437-44. doi: 10.3233/JAD-131124.

PMID:
23979023
32.

Decreased in vitro mitochondrial function is associated with enhanced brain metabolism, blood flow, and memory in Surf1-deficient mice.

Lin AL, Pulliam DA, Deepa SS, Halloran JJ, Hussong SA, Burbank RR, Bresnen A, Liu Y, Podlutskaya N, Soundararajan A, Muir E, Duong TQ, Bokov AF, Viscomi C, Zeviani M, Richardson AG, Van Remmen H, Fox PT, Galvan V.

J Cereb Blood Flow Metab. 2013 Oct;33(10):1605-11. doi: 10.1038/jcbfm.2013.116. Epub 2013 Jul 10.

33.

Chronic rapamycin restores brain vascular integrity and function through NO synthase activation and improves memory in symptomatic mice modeling Alzheimer's disease.

Lin AL, Zheng W, Halloran JJ, Burbank RR, Hussong SA, Hart MJ, Javors M, Shih YY, Muir E, Solano Fonseca R, Strong R, Richardson AG, Lechleiter JD, Fox PT, Galvan V.

J Cereb Blood Flow Metab. 2013 Sep;33(9):1412-21. doi: 10.1038/jcbfm.2013.82. Epub 2013 Jun 26.

34.

Analysis of saliva samples from oncological patients treated with 5-fluorouracil and leucovorin calcium by scanning electron microscopy with energy dispersive system.

Mazzeo MA, Linares JA, López MM, Bachmeier E, Wietz FM, Galván V, Valentinuzzi MC, Riveros JA, Finkelberg A.

J Oral Pathol Med. 2013 Nov;42(10):788-92. doi: 10.1111/jop.12078. Epub 2013 May 6.

PMID:
23647127
35.

The effects of cell phone conversations on the attention and memory of bystanders.

Galván VV, Vessal RS, Golley MT.

PLoS One. 2013;8(3):e58579. doi: 10.1371/journal.pone.0058579. Epub 2013 Mar 13.

36.

Over-expression of heat shock factor 1 phenocopies the effect of chronic inhibition of TOR by rapamycin and is sufficient to ameliorate Alzheimer's-like deficits in mice modeling the disease.

Pierce A, Podlutskaya N, Halloran JJ, Hussong SA, Lin PY, Burbank R, Hart MJ, Galvan V.

J Neurochem. 2013 Mar;124(6):880-93. doi: 10.1111/jnc.12080. Epub 2012 Dec 26.

37.

Environmental enrichment prevents astroglial pathological changes in the hippocampus of APP transgenic mice, model of Alzheimer's disease.

Beauquis J, Pavía P, Pomilio C, Vinuesa A, Podlutskaya N, Galvan V, Saravia F.

Exp Neurol. 2013 Jan;239:28-37. doi: 10.1016/j.expneurol.2012.09.009. Epub 2012 Sep 28.

PMID:
23022919
38.

Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice.

Halloran J, Hussong SA, Burbank R, Podlutskaya N, Fischer KE, Sloane LB, Austad SN, Strong R, Richardson A, Hart MJ, Galvan V.

Neuroscience. 2012 Oct 25;223:102-13. doi: 10.1016/j.neuroscience.2012.06.054. Epub 2012 Jun 28. Erratum in: Neuroscience. 2015 Oct 15;306():151.

39.

Do proteomics analyses provide insights into reduced oxidative stress in the brain of an Alzheimer disease transgenic mouse model with an M631L amyloid precursor protein substitution and thereby the importance of amyloid-beta-resident methionine 35 in Alzheimer disease pathogenesis?

Sultana R, Robinson RA, Lange MB, Fiorini A, Galvan V, Fombonne J, Baker A, Gorostiza O, Zhang J, Cai J, Pierce WM, Bredesen DE, Butterfield DA.

Antioxid Redox Signal. 2012 Dec 1;17(11):1507-14. Epub 2012 Jun 6.

40.

Development of a high-throughput screen targeting caspase-8-mediated cleavage of the amyloid precursor protein.

Hart MJ, Glicksman M, Liu M, Sharma MK, Cuny G, Galvan V.

Anal Biochem. 2012 Feb 15;421(2):467-76. doi: 10.1016/j.ab.2011.11.020. Epub 2011 Dec 1.

PMID:
22178911
41.

Analysis of CpG methylation sites and CGI among human papillomavirus DNA genomes.

Galván SC, Martínez-Salazar M, Galván VM, Méndez R, Díaz-Contreras GT, Alvarado-Hermida M, Alcántara-Silva R, García-Carrancá A.

BMC Genomics. 2011 Nov 25;12:580. doi: 10.1186/1471-2164-12-580.

42.

Endogenously EGFP-Labeled Mouse Embryonic Stem Cells.

Zhang J, Rao RV, Spilman P, Mangada J, Xie L, Vitelli C, Gorostiza OF, Madden DT, Zeng X, Jin K, Hart MJ, Bredesen DE, Galvan V.

Aging Dis. 2011 Feb;2(1):18-29.

43.

Differential expression and redox proteomics analyses of an Alzheimer disease transgenic mouse model: effects of the amyloid-β peptide of amyloid precursor protein.

Robinson RA, Lange MB, Sultana R, Galvan V, Fombonne J, Gorostiza O, Zhang J, Warrier G, Cai J, Pierce WM, Bredesen DE, Butterfield DA.

Neuroscience. 2011 Mar 17;177:207-22. doi: 10.1016/j.neuroscience.2011.01.005. Epub 2011 Jan 9.

44.

Importance of the caspase cleavage site in amyloid-β protein precursor.

Bredesen DE, John V, Galvan V.

J Alzheimers Dis. 2010;22(1):57-63. doi: 10.3233/JAD-2010-100537. Review.

45.

Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease.

Spilman P, Podlutskaya N, Hart MJ, Debnath J, Gorostiza O, Bredesen D, Richardson A, Strong R, Galvan V.

PLoS One. 2010 Apr 1;5(4):e9979. doi: 10.1371/journal.pone.0009979. Erratum in: PLoS One. 2011;6(11). doi:10.1371/annotation/05c1b976-7eab-4154-808d-0526e604b8eb.

46.

In vivo oxidative stress in brain of Alzheimer disease transgenic mice: Requirement for methionine 35 in amyloid beta-peptide of APP.

Butterfield DA, Galvan V, Lange MB, Tang H, Sowell RA, Spilman P, Fombonne J, Gorostiza O, Zhang J, Sultana R, Bredesen DE.

Free Radic Biol Med. 2010 Jan 1;48(1):136-44. doi: 10.1016/j.freeradbiomed.2009.10.035. Epub 2009 Oct 23.

47.

Abnormal neuronal networks and seizure susceptibility in mice overexpressing the APP intracellular domain.

Vogt DL, Thomas D, Galvan V, Bredesen DE, Lamb BT, Pimplikar SW.

Neurobiol Aging. 2011 Sep;32(9):1725-9. doi: 10.1016/j.neurobiolaging.2009.09.002. Epub 2009 Oct 13.

48.

Transplantation of human neural precursor cells in Matrigel scaffolding improves outcome from focal cerebral ischemia after delayed postischemic treatment in rats.

Jin K, Mao X, Xie L, Galvan V, Lai B, Wang Y, Gorostiza O, Wang X, Greenberg DA.

J Cereb Blood Flow Metab. 2010 Mar;30(3):534-44. doi: 10.1038/jcbfm.2009.219. Epub 2009 Oct 14.

49.

Reversal of learning deficits in hAPP transgenic mice carrying a mutation at Asp664: a role for early experience.

Zhang J, Gorostiza OF, Tang H, Bredesen DE, Galvan V.

Behav Brain Res. 2010 Jan 20;206(2):202-7. doi: 10.1016/j.bbr.2009.09.013. Epub 2009 Sep 12.

50.

Netrin-1 interacts with amyloid precursor protein and regulates amyloid-beta production.

Lourenço FC, Galvan V, Fombonne J, Corset V, Llambi F, Müller U, Bredesen DE, Mehlen P.

Cell Death Differ. 2009 May;16(5):655-63. doi: 10.1038/cdd.2008.191. Epub 2009 Jan 16.

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