Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 57


A Novel Sulforaphane-Regulated Gene Network in Suppression of Breast Cancer-Induced Osteolytic Bone Resorption.

Pore SK, Hahm ER, Kim SH, Singh KB, Nyiranshuti L, Latoche JD, Anderson CJ, Adamik J, Galson DL, Weiss KR, Watters RJ, Lee B, Kumta PN, Singh SV.

Mol Cancer Ther. 2020 Feb;19(2):420-431. doi: 10.1158/1535-7163.MCT-19-0611. Epub 2019 Nov 29.


EZH2 Supports Osteoclast Differentiation and Bone Resorption Via Epigenetic and Cytoplasmic Targets.

Adamik J, Pulugulla SH, Zhang P, Sun Q, Lontos K, Macar DA, Auron PE, Galson DL.

J Bone Miner Res. 2020 Jan;35(1):181-195. doi: 10.1002/jbmr.3863. Epub 2019 Oct 23.


Epigenetic-Based Mechanisms of Osteoblast Suppression in Multiple Myeloma Bone Disease.

Adamik J, Roodman GD, Galson DL.

JBMR Plus. 2019 Mar 15;3(3):e10183. doi: 10.1002/jbm4.10183. eCollection 2019 Mar. Review.


Osteoblast suppression in multiple myeloma bone disease.

Adamik J, Galson DL, Roodman GD.

J Bone Oncol. 2018 Sep 15;13:62-70. doi: 10.1016/j.jbo.2018.09.001. eCollection 2018 Nov. Review.


A combined computational and experimental approach reveals the structure of a C/EBPβ-Spi1 interaction required for IL1B gene transcription.

Pulugulla SH, Workman R, Rutter NW, Yang Z, Adamik J, Lupish B, Macar DA, El Abdouni S, Esposito EX, Galson DL, Camacho CJ, Madura JD, Auron PE.

J Biol Chem. 2018 Dec 28;293(52):19942-19956. doi: 10.1074/jbc.RA118.005627. Epub 2018 Oct 24.


Distinct mechanisms regulate IL1B gene transcription in lymphoid CD4 T cells and monocytes.

Pulugulla SH, Packard TA, Galloway NLK, Grimmett ZW, Doitsh G, Adamik J, Galson DL, Greene WC, Auron PE.

Cytokine. 2018 Nov;111:373-381. doi: 10.1016/j.cyto.2018.10.001. Epub 2018 Oct 6.


Growth factor independence 1 expression in myeloma cells enhances their growth, survival, and osteoclastogenesis.

Petrusca DN, Toscani D, Wang FM, Park C, Crean CD, Anderson JL, Marino S, Mohammad KS, Zhou D, Silbermann R, Sun Q, Kurihara N, Galson DL, Giuliani N, Roodman GD.

J Hematol Oncol. 2018 Oct 4;11(1):123. doi: 10.1186/s13045-018-0666-5.


XRK3F2 Inhibition of p62-ZZ Domain Signaling Rescues Myeloma-Induced GFI1-Driven Epigenetic Repression of the Runx2 Gene in Pre-osteoblasts to Overcome Differentiation Suppression.

Adamik J, Silbermann R, Marino S, Sun Q, Anderson JL, Zhou D, Xie XQ, Roodman GD, Galson DL.

Front Endocrinol (Lausanne). 2018 Jun 29;9:344. doi: 10.3389/fendo.2018.00344. eCollection 2018.


The Role of Semaphorin 4D in Bone Remodeling and Cancer Metastasis.

Lontos K, Adamik J, Tsagianni A, Galson DL, Chirgwin JM, Suvannasankha A.

Front Endocrinol (Lausanne). 2018 Jun 19;9:322. doi: 10.3389/fendo.2018.00322. eCollection 2018. Review.


EZH2 or HDAC1 Inhibition Reverses Multiple Myeloma-Induced Epigenetic Suppression of Osteoblast Differentiation.

Adamik J, Jin S, Sun Q, Zhang P, Weiss KR, Anderson JL, Silbermann R, Roodman GD, Galson DL.

Mol Cancer Res. 2017 Apr;15(4):405-417. doi: 10.1158/1541-7786.MCR-16-0242-T. Epub 2017 Jan 23.


Kindlin-2 controls TGF-β signalling and Sox9 expression to regulate chondrogenesis.

Wu C, Jiao H, Lai Y, Zheng W, Chen K, Qu H, Deng W, Song P, Zhu K, Cao H, Galson DL, Fan J, Im HJ, Liu Y, Chen J, Chen D, Xiao G.

Nat Commun. 2015 Jul 7;6:7531. doi: 10.1038/ncomms8531.


Pathobiology of Paget's Disease of Bone.

Galson DL, Roodman GD.

J Bone Metab. 2014 May;21(2):85-98. doi: 10.11005/jbm.2014.21.2.85. Epub 2014 May 31. Review.


Increased IL-6 expression in osteoclasts is necessary but not sufficient for the development of Paget's disease of bone.

Teramachi J, Zhou H, Subler MA, Kitagawa Y, Galson DL, Dempster DW, Windle JJ, Kurihara N, Roodman GD.

J Bone Miner Res. 2014 Jun;29(6):1456-65. doi: 10.1002/jbmr.2158.


Distinct mechanisms for induction and tolerance regulate the immediate early genes encoding interleukin 1β and tumor necrosis factor α.

Adamik J, Wang KZ, Unlu S, Su AJ, Tannahill GM, Galson DL, O'Neill LA, Auron PE.

PLoS One. 2013 Aug 1;8(8):e70622. doi: 10.1371/journal.pone.0070622. Print 2013.


TBK1 mediates critical effects of measles virus nucleocapsid protein (MVNP) on pagetic osteoclast formation.

Sun Q, Sammut B, Wang FM, Kurihara N, Windle JJ, Roodman GD, Galson DL.

J Bone Miner Res. 2014 Jan;29(1):90-102. doi: 10.1002/jbmr.2026.


ATF4 promotes bone angiogenesis by increasing VEGF expression and release in the bone environment.

Zhu K, Jiao H, Li S, Cao H, Galson DL, Zhao Z, Zhao X, Lai Y, Fan J, Im HJ, Chen D, Xiao G.

J Bone Miner Res. 2013 Sep;28(9):1870-1884. doi: 10.1002/jbmr.1958.


Role of ATF7-TAF12 interactions in the vitamin D response hypersensitivity of osteoclast precursors in Paget's disease.

Teramachi J, Hiruma Y, Ishizuka S, Ishizuka H, Brown JP, Michou L, Cao H, Galson DL, Subler MA, Zhou H, Dempster DW, Windle JJ, Roodman GD, Kurihara N.

J Bone Miner Res. 2013 Jun;28(6):1489-500. doi: 10.1002/jbmr.1884.


Measles virus nucleocapsid protein, a key contributor to Paget's disease, increases IL-6 expression via down-regulation of FoxO3/Sirt1 signaling.

Wang FM, Sarmasik A, Hiruma Y, Sun Q, Sammut B, Windle JJ, Roodman GD, Galson DL.

Bone. 2013 Mar;53(1):269-76. doi: 10.1016/j.bone.2012.12.007. Epub 2012 Dec 20.


Annexin II interactions with the annexin II receptor enhance multiple myeloma cell adhesion and growth in the bone marrow microenvironment.

D'Souza S, Kurihara N, Shiozawa Y, Joseph J, Taichman R, Galson DL, Roodman GD.

Blood. 2012 Feb 23;119(8):1888-96. doi: 10.1182/blood-2011-11-393348. Epub 2012 Jan 5.


Mechanisms of multiple myeloma bone disease.

Galson DL, Silbermann R, Roodman GD.

Bonekey Rep. 2012 Aug 1;1:135. doi: 10.1038/bonekey.2012.135. eCollection 2012.


Gfi1 expressed in bone marrow stromal cells is a novel osteoblast suppressor in patients with multiple myeloma bone disease.

D'Souza S, del Prete D, Jin S, Sun Q, Huston AJ, Kostov FE, Sammut B, Hong CS, Anderson JL, Patrene KD, Yu S, Velu CS, Xiao G, Grimes HL, Roodman GD, Galson DL.

Blood. 2011 Dec 22;118(26):6871-80. doi: 10.1182/blood-2011-04-346775. Epub 2011 Oct 31.


Resveratrol triggers the pro-apoptotic endoplasmic reticulum stress response and represses pro-survival XBP1 signaling in human multiple myeloma cells.

Wang FM, Galson DL, Roodman GD, Ouyang H.

Exp Hematol. 2011 Oct;39(10):999-1006. doi: 10.1016/j.exphem.2011.06.007. Epub 2011 Jul 1.


IMiD immunomodulatory compounds block C/EBP{beta} translation through eIF4E down-regulation resulting in inhibition of MM.

Li S, Pal R, Monaghan SA, Schafer P, Ouyang H, Mapara M, Galson DL, Lentzsch S.

Blood. 2011 May 12;117(19):5157-65. doi: 10.1182/blood-2010-10-314278. Epub 2011 Mar 9.


Contributions of the measles virus nucleocapsid gene and the SQSTM1/p62(P392L) mutation to Paget's disease.

Kurihara N, Hiruma Y, Yamana K, Michou L, Rousseau C, Morissette J, Galson DL, Teramachi J, Zhou H, Dempster DW, Windle JJ, Brown JP, Roodman GD.

Cell Metab. 2011 Jan 5;13(1):23-34. doi: 10.1016/j.cmet.2010.12.002.


ADAM8 enhances osteoclast precursor fusion and osteoclast formation in vitro and in vivo.

Ishizuka H, García-Palacios V, Lu G, Subler MA, Zhang H, Boykin CS, Choi SJ, Zhao L, Patrene K, Galson DL, Blair HC, Hadi TM, Windle JJ, Kurihara N, Roodman GD.

J Bone Miner Res. 2011 Jan;26(1):169-81. doi: 10.1002/jbmr.199.


Activating transcription factor 4 regulates osteoclast differentiation in mice.

Cao H, Yu S, Yao Z, Galson DL, Jiang Y, Zhang X, Fan J, Lu B, Guan Y, Luo M, Lai Y, Zhu Y, Kurihara N, Patrene K, Roodman GD, Xiao G.

J Clin Invest. 2010 Aug;120(8):2755-66. doi: 10.1172/JCI42106. Epub 2010 Jul 12.


TRAF6 is autoinhibited by an intramolecular interaction which is counteracted by trans-ubiquitination.

Wang KZ, Galson DL, Auron PE.

J Cell Biochem. 2010 Jun 1;110(3):763-71. doi: 10.1002/jcb.22589.


C/EBPbeta regulates transcription factors critical for proliferation and survival of multiple myeloma cells.

Pal R, Janz M, Galson DL, Gries M, Li S, Jöhrens K, Anagnostopoulos I, Dörken B, Mapara MY, Borghesi L, Kardava L, Roodman GD, Milcarek C, Lentzsch S.

Blood. 2009 Oct 29;114(18):3890-8. doi: 10.1182/blood-2009-01-201111. Epub 2009 Aug 28.


Oncostatin M-induced CCL2 transcription in osteoblastic cells is mediated by multiple levels of STAT-1 and STAT-3 signaling: an implication for the pathogenesis of arthritis.

Kok SH, Hong CY, Kuo MY, Wang CC, Hou KL, Lin YT, Galson DL, Lin SK.

Arthritis Rheum. 2009 May;60(5):1451-62. doi: 10.1002/art.24452.


Activating transcription factor 4 is critical for proliferation and survival in primary bone marrow stromal cells and calvarial osteoblasts.

Zhang X, Yu S, Galson DL, Luo M, Fan J, Zhang J, Guan Y, Xiao G.

J Cell Biochem. 2008 Oct 15;105(3):885-95. doi: 10.1002/jcb.21888.


CXCL16 functions as a novel chemotactic factor for prostate cancer cells in vitro.

Lu Y, Wang J, Xu Y, Koch AE, Cai Z, Chen X, Galson DL, Taichman RS, Zhang J.

Mol Cancer Res. 2008 Apr;6(4):546-54. doi: 10.1158/1541-7786.MCR-07-0277. Epub 2008 Mar 14.


General transcription factor IIA-gamma increases osteoblast-specific osteocalcin gene expression via activating transcription factor 4 and runt-related transcription factor 2.

Yu S, Jiang Y, Galson DL, Luo M, Lai Y, Lu Y, Ouyang HJ, Zhang J, Xiao G.

J Biol Chem. 2008 Feb 29;283(9):5542-53. doi: 10.1074/jbc.M705653200. Epub 2008 Jan 2.


Phosphorylation of IRF8 in a pre-associated complex with Spi-1/PU.1 and non-phosphorylated Stat1 is critical for LPS induction of the IL1B gene.

Unlu S, Kumar A, Waterman WR, Tsukada J, Wang KZ, Galson DL, Auron PE.

Mol Immunol. 2007 Jul;44(13):3364-79. Epub 2007 Mar 26.


Eosinophil chemotactic factor-L (ECF-L) enhances osteoclast formation by increasing in osteoclast precursors expression of LFA-1 and ICAM-1.

Garcia-Palacios V, Chung HY, Choi SJ, Sarmasik A, Kurihara N, Lee JW, Galson DL, Collins R, Roodman GD.

Bone. 2007 Feb;40(2):316-22. Epub 2006 Sep 25.


Monocyte chemotactic protein-1 (MCP-1) acts as a paracrine and autocrine factor for prostate cancer growth and invasion.

Lu Y, Cai Z, Galson DL, Xiao G, Liu Y, George DE, Melhem MF, Yao Z, Zhang J.

Prostate. 2006 Sep 1;66(12):1311-8.


TRAF6 activation of PI 3-kinase-dependent cytoskeletal changes is cooperative with Ras and is mediated by an interaction with cytoplasmic Src.

Wang KZ, Wara-Aswapati N, Boch JA, Yoshida Y, Hu CD, Galson DL, Auron PE.

J Cell Sci. 2006 Apr 15;119(Pt 8):1579-91. Epub 2006 Mar 28.


Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-Fos.

Matsuo K, Galson DL, Zhao C, Peng L, Laplace C, Wang KZ, Bachler MA, Amano H, Aburatani H, Ishikawa H, Wagner EF.

J Biol Chem. 2004 Jun 18;279(25):26475-80. Epub 2004 Apr 8.


Amylin inhibits bone resorption while the calcitonin receptor controls bone formation in vivo.

Dacquin R, Davey RA, Laplace C, Levasseur R, Morris HA, Goldring SR, Gebre-Medhin S, Galson DL, Zajac JD, Karsenty G.

J Cell Biol. 2004 Feb 16;164(4):509-14.


Estrogen receptor-related receptor alpha impinges on the estrogen axis in bone: potential function in osteoporosis.

Bonnelye E, Kung V, Laplace C, Galson DL, Aubin JE.

Endocrinology. 2002 Sep;143(9):3658-70.


Dual regulatory role of human cytomegalovirus immediate-early protein in IL1B transcription is dependent upon Spi-1/PU.1.

Yang Z, Wara-aswapati N, Yoshida Y, Walker N, Galson DL, Listman J, Auron PE.

Biochem Biophys Res Commun. 2002 Jun 21;294(4):854-63.


Tissue-specific and ubiquitous promoters direct the expression of alternatively spliced transcripts from the calcitonin receptor gene.

Anusaksathien O, Laplace C, Li X, Ren Y, Peng L, Goldring SR, Galson DL.

J Biol Chem. 2001 Jun 22;276(25):22663-74. Epub 2001 Apr 17.


The role of TNF-receptor family members and other TRAF-dependent receptors in bone resorption.

Gravallese EM, Galson DL, Goldring SR, Auron PE.

Arthritis Res. 2001;3(1):6-12. Epub 2000 Nov 2. Review.


Calcitonin-dependent down-regulation of the mouse C1a calcitonin receptor in cells of the osteoclast lineage involves a transcriptional mechanism.

Inoue D, Shih C, Galson DL, Goldring SR, Horne WC, Baron R.

Endocrinology. 1999 Mar;140(3):1060-8.


Immortalization of osteoclast precursors by targeting Bcl -XL and Simian virus 40 large T antigen to the osteoclast lineage in transgenic mice.

Hentunen TA, Reddy SV, Boyce BF, Devlin R, Park HR, Chung H, Selander KS, Dallas M, Kurihara N, Galson DL, Goldring SR, Koop BA, Windle JJ, Roodman GD.

J Clin Invest. 1998 Jul 1;102(1):88-97.


Phospholipase D- and protein kinase C isoenzyme-dependent signal transduction pathways activated by the calcitonin receptor.

Naro F, Perez M, Migliaccio S, Galson DL, Orcel P, Teti A, Goldring SR.

Endocrinology. 1998 Jul;139(7):3241-8.


Cis elements that regulate the erythropoietin gene.

Galson DL, Blanchard KL, Fandrey J, Goldberg MA, Bunn HF.

Ann N Y Acad Sci. 1994 Apr 15;718:21-30. Review. No abstract available.


Supplemental Content

Loading ...
Support Center