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Items: 1 to 50 of 58

1.

eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways.

Cramer Z, Sadek J, Vazquez GG, Di Marco S, Pause A, Pelletier J, Gallouzi IE.

Sci Rep. 2018 May 30;8(1):8414. doi: 10.1038/s41598-018-26625-9.

2.

The AMPK agonist 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation-associated cachectic muscle wasting.

Hall DT, Griss T, Ma JF, Sanchez BJ, Sadek J, Tremblay AMK, Mubaid S, Omer A, Ford RJ, Bedard N, Pause A, Wing SS, Di Marco S, Steinberg GR, Jones RG, Gallouzi IE.

EMBO Mol Med. 2018 May 29. pii: e8307. doi: 10.15252/emmm.201708307. [Epub ahead of print]

3.

Stress granules counteract senescence by sequestration of PAI-1.

Omer A, Patel D, Lian XJ, Sadek J, Di Marco S, Pause A, Gorospe M, Gallouzi IE.

EMBO Rep. 2018 May;19(5). pii: e44722. doi: 10.15252/embr.201744722. Epub 2018 Mar 28.

4.

STAT3 promotes IFNγ/TNFα-induced muscle wasting in an NF-κB-dependent and IL-6-independent manner.

Ma JF, Sanchez BJ, Hall DT, Tremblay AK, Di Marco S, Gallouzi IE.

EMBO Mol Med. 2017 May;9(5):622-637. doi: 10.15252/emmm.201607052.

5.

Genetic testing and genomic analysis: a debate on ethical, social and legal issues in the Arab world with a focus on Qatar.

El Shanti H, Chouchane L, Badii R, Gallouzi IE, Gasparini P.

J Transl Med. 2015 Nov 14;13:358. doi: 10.1186/s12967-015-0720-9. Review.

6.

eEF2 and Ras-GAP SH3 domain-binding protein (G3BP1) modulate stress granule assembly during HIV-1 infection.

Valiente-Echeverría F, Melnychuk L, Vyboh K, Ajamian L, Gallouzi IE, Bernard N, Mouland AJ.

Nat Commun. 2014 Sep 17;5:4819. doi: 10.1038/ncomms5819.

7.

Destabilization of nucleophosmin mRNA by the HuR/KSRP complex is required for muscle fibre formation.

Cammas A, Sanchez BJ, Lian XJ, Dormoy-Raclet V, van der Giessen K, López de Silanes I, Ma J, Wilusz C, Richardson J, Gorospe M, Millevoi S, Giovarelli M, Gherzi R, Di Marco S, Gallouzi IE.

Nat Commun. 2014 Jun 27;5:4190. doi: 10.1038/ncomms5190.

8.

An invitation to the 2nd Cancer Cachexia Conference, Montréal, Canada.

Guttridge D, Couch M, Di Marco S, Gallouzi IE, Zitzmann ND, Baracos V, Rudnicki M, Tremblay M, Zimmers T.

J Cachexia Sarcopenia Muscle. 2014 Sep;5(3):181. doi: 10.1007/s13539-014-0150-1. Epub 2014 Jun 26. No abstract available.

9.

Available for a limited time only: Regulating gene expression through mRNA turnover.

Gallouzi IE, von Roretz C.

Semin Cell Dev Biol. 2014 Oct;34:1. doi: 10.1016/j.semcdb.2014.06.008. Epub 2014 Jun 14. No abstract available.

PMID:
24937128
10.

Planning your every move: the role of β-actin and its post-transcriptional regulation in cell motility.

Artman L, Dormoy-Raclet V, von Roretz C, Gallouzi IE.

Semin Cell Dev Biol. 2014 Oct;34:33-43. doi: 10.1016/j.semcdb.2014.05.012. Epub 2014 May 27. Review.

PMID:
24878350
11.

Regulation of eukaryotic initiation factor 4AII by MyoD during murine myogenic cell differentiation.

Galicia-Vázquez G, Di Marco S, Lian XJ, Ma JF, Gallouzi IE, Pelletier J.

PLoS One. 2014 Jan 23;9(1):e87237. doi: 10.1371/journal.pone.0087237. eCollection 2014.

12.

Aryl hydrocarbon receptor-dependent retention of nuclear HuR suppresses cigarette smoke-induced cyclooxygenase-2 expression independent of DNA-binding.

Zago M, Sheridan JA, Nair P, Rico de Souza A, Gallouzi IE, Rousseau S, Di Marco S, Hamid Q, Eidelman DH, Baglole CJ.

PLoS One. 2013 Sep 27;8(9):e74953. doi: 10.1371/journal.pone.0074953. eCollection 2013.

13.

HuR and miR-1192 regulate myogenesis by modulating the translation of HMGB1 mRNA.

Dormoy-Raclet V, Cammas A, Celona B, Lian XJ, van der Giessen K, Zivojnovic M, Brunelli S, Riuzzi F, Sorci G, Wilhelm BT, Di Marco S, Donato R, Bianchi ME, Gallouzi IE.

Nat Commun. 2013;4:2388. doi: 10.1038/ncomms3388.

14.

A DIStinctively novel exoribonuclease that really likes U.

Gallouzi IE, Wilusz J.

EMBO J. 2013 Jul 3;32(13):1799-801. doi: 10.1038/emboj.2013.136. Epub 2013 Jun 11.

15.

Post-transcriptional regulation of connexin43 in H-Ras-transformed cells.

Kandouz M, Zhao J, Bier A, Di Marco S, Oviedo-Landaverde I, Gallouzi IE, Batist G.

PLoS One. 2013;8(3):e58500. doi: 10.1371/journal.pone.0058500. Epub 2013 Mar 11.

16.

Apoptotic-induced cleavage shifts HuR from being a promoter of survival to an activator of caspase-mediated apoptosis.

von Roretz C, Lian XJ, Macri AM, Punjani N, Clair E, Drouin O, Dormoy-Raclet V, Ma JF, Gallouzi IE.

Cell Death Differ. 2013 Jan;20(1):154-68. doi: 10.1038/cdd.2012.111. Epub 2012 Sep 7.

17.

Quantitative proteomics and dynamic imaging reveal that G3BP-mediated stress granule assembly is poly(ADP-ribose)-dependent following exposure to MNNG-induced DNA alkylation.

Isabelle M, Gagné JP, Gallouzi IE, Poirier GG.

J Cell Sci. 2012 Oct 1;125(Pt 19):4555-66. doi: 10.1242/jcs.106963. Epub 2012 Jul 5.

18.

The translation inhibitor pateamine A prevents cachexia-induced muscle wasting in mice.

Di Marco S, Cammas A, Lian XJ, Kovacs EN, Ma JF, Hall DT, Mazroui R, Richardson J, Pelletier J, Gallouzi IE.

Nat Commun. 2012 Jun 12;3:896. doi: 10.1038/ncomms1899.

19.

The impact of mRNA turnover and translation on age-related muscle loss.

Ma JF, Hall DT, Gallouzi IE.

Ageing Res Rev. 2012 Sep;11(4):432-41. doi: 10.1016/j.arr.2012.05.004. Epub 2012 Jun 9. Review.

PMID:
22687959
20.

PARP1 parylation promotes silent locus transmission in the nucleolus: the suspicion confirmed.

Isabelle M, Gallouzi IE, Poirier GG.

Mol Cell. 2012 Mar 30;45(6):706-7. doi: 10.1016/j.molcel.2012.03.012.

21.

Targeting protein synthesis in a Myc/mTOR-driven model of anorexia-cachexia syndrome delays its onset and prolongs survival.

Robert F, Mills JR, Agenor A, Wang D, DiMarco S, Cencic R, Tremblay ML, Gallouzi IE, Hekimi S, Wing SS, Pelletier J.

Cancer Res. 2012 Feb 1;72(3):747-56. doi: 10.1158/0008-5472.CAN-11-2739. Epub 2011 Dec 12.

22.

Turnover of AU-rich-containing mRNAs during stress: a matter of survival.

von Roretz C, Di Marco S, Mazroui R, Gallouzi IE.

Wiley Interdiscip Rev RNA. 2011 May-Jun;2(3):336-47. doi: 10.1002/wrna.55. Epub 2010 Oct 19. Review.

PMID:
21957021
23.

Inducible nitric oxide synthase (iNOS) in muscle wasting syndrome, sarcopenia, and cachexia.

Hall DT, Ma JF, Marco SD, Gallouzi IE.

Aging (Albany NY). 2011 Aug;3(8):702-15. Review.

24.

Transportin 2 regulates apoptosis through the RNA-binding protein HuR.

von Roretz C, Macri AM, Gallouzi IE.

J Biol Chem. 2011 Jul 22;286(29):25983-91. doi: 10.1074/jbc.M110.216184. Epub 2011 Jun 6.

25.

Down-regulation of cytokine-induced interleukin-8 requires inhibition of p38 mitogen-activated protein kinase (MAPK) via MAPK phosphatase 1-dependent and -independent mechanisms.

Dauletbaev N, Eklove D, Mawji N, Iskandar M, Di Marco S, Gallouzi IE, Lands LC.

J Biol Chem. 2011 May 6;286(18):15998-6007. doi: 10.1074/jbc.M110.205724. Epub 2011 Mar 15.

26.

HuR and myogenesis: being in the right place at the right time.

von Roretz C, Beauchamp P, Di Marco S, Gallouzi IE.

Biochim Biophys Acta. 2011 Sep;1813(9):1663-7. doi: 10.1016/j.bbamcr.2011.01.036. Epub 2011 Feb 20. Review.

27.

FasL expression in activated T lymphocytes involves HuR-mediated stabilization.

Drury GL, Di Marco S, Dormoy-Raclet V, Desbarats J, Gallouzi IE.

J Biol Chem. 2010 Oct 8;285(41):31130-8. doi: 10.1074/jbc.M110.137919. Epub 2010 Jul 30.

28.

The cleavage of HuR interferes with its transportin-2-mediated nuclear import and promotes muscle fiber formation.

Beauchamp P, Nassif C, Hillock S, van der Giessen K, von Roretz C, Jasmin BJ, Gallouzi IE.

Cell Death Differ. 2010 Oct;17(10):1588-99. doi: 10.1038/cdd.2010.34. Epub 2010 Apr 9.

29.

Protein kinase RNA/FADD/caspase-8 pathway mediates the proapoptotic activity of the RNA-binding protein human antigen R (HuR).

von Roretz C, Gallouzi IE.

J Biol Chem. 2010 May 28;285(22):16806-13. doi: 10.1074/jbc.M109.087320. Epub 2010 Mar 30.

30.

Could stress granules be involved in age-related diseases?

Gallouzi IE.

Aging (Albany NY). 2009 Sep 21;1(9):753-7. No abstract available.

31.

Tristetraprolin: a weapon against HPV-induced cervical cancer?

Gallouzi IE, Di Marco S.

Aging (Albany NY). 2009 Oct 8;1(10):839-41. No abstract available.

32.

Akt2-mediated phosphorylation of Pitx2 controls Ccnd1 mRNA decay during muscle cell differentiation.

Gherzi R, Trabucchi M, Ponassi M, Gallouzi IE, Rosenfeld MG, Briata P.

Cell Death Differ. 2010 Jun;17(6):975-83. doi: 10.1038/cdd.2009.194. Epub 2009 Dec 18.

33.

The Elav-like protein HuR exerts translational control of viral internal ribosome entry sites.

Rivas-Aravena A, Ramdohr P, Vallejos M, Valiente-Echeverría F, Dormoy-Raclet V, Rodríguez F, Pino K, Holzmann C, Huidobro-Toro JP, Gallouzi IE, López-Lastra M.

Virology. 2009 Sep 30;392(2):178-85. doi: 10.1016/j.virol.2009.06.050. Epub 2009 Aug 3.

34.

Oxidative Stress Increases the Number of Stress Granules in Senescent Cells and Triggers a Rapid Decrease in p21waf1/cip1 Translation.

Lian XJ, Gallouzi IE.

J Biol Chem. 2009 Mar 27;284(13):8877-87. doi: 10.1074/jbc.M806372200. Epub 2009 Jan 28.

35.

2',3'-Cyclic nucleotide 3'-phosphodiesterase: a novel RNA-binding protein that inhibits protein synthesis.

Gravel M, Robert F, Kottis V, Gallouzi IE, Pelletier J, Braun PE.

J Neurosci Res. 2009 Apr;87(5):1069-79. doi: 10.1002/jnr.21939.

PMID:
19021295
36.

Decoding ARE-mediated decay: is microRNA part of the equation?

von Roretz C, Gallouzi IE.

J Cell Biol. 2008 Apr 21;181(2):189-94. doi: 10.1083/jcb.200712054. Epub 2008 Apr 14. Review.

37.

Caspase-mediated cleavage of HuR in the cytoplasm contributes to pp32/PHAP-I regulation of apoptosis.

Mazroui R, Di Marco S, Clair E, von Roretz C, Tenenbaum SA, Keene JD, Saleh M, Gallouzi IE.

J Cell Biol. 2008 Jan 14;180(1):113-27. doi: 10.1083/jcb.200709030. Epub 2008 Jan 7.

38.

Solution structure of YaeO, a Rho-specific inhibitor of transcription termination.

Gutiérrez P, Kozlov G, Gabrielli L, Elias D, Osborne MJ, Gallouzi IE, Gehring K.

J Biol Chem. 2007 Aug 10;282(32):23348-53. Epub 2007 Jun 11.

39.

The RNA-binding protein HuR promotes cell migration and cell invasion by stabilizing the beta-actin mRNA in a U-rich-element-dependent manner.

Dormoy-Raclet V, Ménard I, Clair E, Kurban G, Mazroui R, Di Marco S, von Roretz C, Pause A, Gallouzi IE.

Mol Cell Biol. 2007 Aug;27(15):5365-80. Epub 2007 Jun 4.

40.

Involvement of transportin 2-mediated HuR import in muscle cell differentiation.

van der Giessen K, Gallouzi IE.

Mol Biol Cell. 2007 Jul;18(7):2619-29. Epub 2007 May 2.

41.

Inhibition of the ubiquitin-proteasome system induces stress granule formation.

Mazroui R, Di Marco S, Kaufman RJ, Gallouzi IE.

Mol Biol Cell. 2007 Jul;18(7):2603-18. Epub 2007 May 2.

42.

Inhibition of ribosome recruitment induces stress granule formation independently of eukaryotic initiation factor 2alpha phosphorylation.

Mazroui R, Sukarieh R, Bordeleau ME, Kaufman RJ, Northcote P, Tanaka J, Gallouzi I, Pelletier J.

Mol Biol Cell. 2006 Oct;17(10):4212-9. Epub 2006 Jul 26.

43.

RNA-binding protein HuR is required for stabilization of SLC11A1 mRNA and SLC11A1 protein expression.

Xu YZ, Di Marco S, Gallouzi I, Rola-Pleszczynski M, Radzioch D.

Mol Cell Biol. 2005 Sep;25(18):8139-49.

44.

NF-kappa B-mediated MyoD decay during muscle wasting requires nitric oxide synthase mRNA stabilization, HuR protein, and nitric oxide release.

Di Marco S, Mazroui R, Dallaire P, Chittur S, Tenenbaum SA, Radzioch D, Marette A, Gallouzi IE.

Mol Cell Biol. 2005 Aug;25(15):6533-45.

45.

Nuclear localization of the adenovirus E4orf4 protein is mediated through an arginine-rich motif and correlates with cell death.

Miron MJ, Gallouzi IE, Lavoie JN, Branton PE.

Oncogene. 2004 Sep 30;23(45):7458-68. Erratum in: Oncogene. 2005 Jun 9;24(25):4162.

PMID:
15334069
46.

Protein ligands mediate the CRM1-dependent export of HuR in response to heat shock.

Gallouzi IE, Brennan CM, Steitz JA.

RNA. 2003 Nov;9(11):1410. No abstract available.

47.

RNAi-mediated HuR depletion leads to the inhibition of muscle cell differentiation.

van der Giessen K, Di-Marco S, Clair E, Gallouzi IE.

J Biol Chem. 2003 Nov 21;278(47):47119-28. Epub 2003 Aug 27.

48.

Delineation of mRNA export pathways by the use of cell-permeable peptides.

Gallouzi IE, Steitz JA.

Science. 2001 Nov 30;294(5548):1895-901. Erratum in: Science 2002 Apr 5;296(5565):47.

49.

RasGAP-associated endoribonuclease G3Bp: selective RNA degradation and phosphorylation-dependent localization.

Tourrière H, Gallouzi IE, Chebli K, Capony JP, Mouaikel J, van der Geer P, Tazi J.

Mol Cell Biol. 2001 Nov;21(22):7747-60.

50.

Protein ligands mediate the CRM1-dependent export of HuR in response to heat shock.

Gallouzi IE, Brennan CM, Steitz JA.

RNA. 2001 Sep;7(9):1348-61. Erratum in: RNA. 2003 Nov;9(11):1410.

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