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Items: 1 to 50 of 120

1.

Adenovirus 5 E1A is responsible for increased expression of insulin receptor substrate 4 in established adenovirus 5-transformed cell lines and interacts with IRS components activating the PI3 kinase/Akt signalling pathway.

Shimwell NJ, Martin A, Bruton RK, Blackford AN, Sedgwick GG, Gallimore PH, Turnell AS, Grand RJ.

Oncogene. 2009 Feb 5;28(5):686-97. doi: 10.1038/onc.2008.417. Epub 2008 Nov 24.

PMID:
19029952
2.

Identification of an arginine-rich motif in human papillomavirus type 1 E1;E4 protein necessary for E4-mediated inhibition of cellular DNA synthesis in vitro and in cells.

Roberts S, Kingsbury SR, Stoeber K, Knight GL, Gallimore PH, Williams GH.

J Virol. 2008 Sep;82(18):9056-64. doi: 10.1128/JVI.01080-08. Epub 2008 Jul 16.

3.

The effect of CtBP1 binding on the structure of the C-terminal region of adenovirus 12 early region 1A.

Molloy DP, Barral PM, Gallimore PH, Grand RJ.

Virology. 2007 Jul 5;363(2):342-56. Epub 2007 Mar 1.

4.
5.

Roles for APIS and the 20S proteasome in adenovirus E1A-dependent transcription.

Rasti M, Grand RJ, Yousef AF, Shuen M, Mymryk JS, Gallimore PH, Turnell AS.

EMBO J. 2006 Jun 21;25(12):2710-22. Epub 2006 Jun 8.

6.

The APC/C and CBP/p300 cooperate to regulate transcription and cell-cycle progression.

Turnell AS, Stewart GS, Grand RJ, Rookes SM, Martin A, Yamano H, Elledge SJ, Gallimore PH.

Nature. 2005 Dec 1;438(7068):690-5.

PMID:
16319895
7.

Accumulation of p53 in response to adenovirus early region 1A sensitizes human cells to tumor necrosis factor alpha-induced apoptosis.

Zhang X, Hussain R, Turnell AS, Mymryk JS, Gallimore PH, Grand RJ.

Virology. 2005 Sep 30;340(2):285-95.

8.

T-cell responses to human papillomavirus type 16 among women with different grades of cervical neoplasia.

Steele JC, Mann CH, Rookes S, Rollason T, Murphy D, Freeth MG, Gallimore PH, Roberts S.

Br J Cancer. 2005 Jul 25;93(2):248-59.

9.

The interaction of the hnRNP family member E1B-AP5 with p53.

Barral PM, Rusch A, Turnell AS, Gallimore PH, Byrd PJ, Dobner T, Grand RJ.

FEBS Lett. 2005 May 23;579(13):2752-8. Epub 2005 Apr 20.

10.

Recruitment of CBP/p300, TATA-binding protein, and S8 to distinct regions at the N terminus of adenovirus E1A.

Rasti M, Grand RJ, Mymryk JS, Gallimore PH, Turnell AS.

J Virol. 2005 May;79(9):5594-605.

11.
12.

The targeting of the proteasomal regulatory subunit S2 by adenovirus E1A causes inhibition of proteasomal activity and increased p53 expression.

Zhang X, Turnell AS, Gorbea C, Mymryk JS, Gallimore PH, Grand RJ.

J Biol Chem. 2004 Jun 11;279(24):25122-33. Epub 2004 Mar 31.

13.

Human papillomavirus (HPV) type 16-specific CD8+ T cell responses in women with high grade vulvar intraepithelial neoplasia.

Todd RW, Roberts S, Mann CH, Luesley DM, Gallimore PH, Steele JC.

Int J Cancer. 2004 Mar 1;108(6):857-62.

15.

Caspase-mediated cleavage of adenovirus early region 1A proteins.

Grand RJ, Schmeiser K, Gordon EM, Zhang X, Gallimore PH, Turnell AS.

Virology. 2002 Sep 30;301(2):255-71.

16.
18.

Adenovirus E1A: remodelling the host cell, a life or death experience.

Gallimore PH, Turnell AS.

Oncogene. 2001 Nov 26;20(54):7824-35. Review. No abstract available.

19.
20.

Structural determinants in adenovirus 12 E1A involved in the interaction with C-terminal binding protein 1.

Molloy DP, Barral PM, Bremner KH, Gallimore PH, Grand RJ.

Virology. 2000 Nov 10;277(1):156-66.

21.

Regulation of the 26S proteasome by adenovirus E1A.

Turnell AS, Grand RJ, Gorbea C, Zhang X, Wang W, Mymryk JS, Gallimore PH.

EMBO J. 2000 Sep 1;19(17):4759-73.

22.

Neutralisation of adenovirus infectivity by ascitic fluid from ovarian cancer patients.

Stallwood Y, Fisher KD, Gallimore PH, Mautner V.

Gene Ther. 2000 Apr;7(8):637-43.

23.
24.

Definition of a major p53 binding site on Ad2E1B58K protein and a possible nuclear localization signal on the Ad12E1B54K protein.

Grand RJ, Parkhill J, Szestak T, Rookes SM, Roberts S, Gallimore PH.

Oncogene. 1999 Jan 28;18(4):955-65.

25.
26.

Adenovirus early region 1A protein binds to mammalian SUG1-a regulatory component of the proteasome.

Grand RJ, Turnell AS, Mason GG, Wang W, Milner AE, Mymryk JS, Rookes SM, Rivett AJ, Gallimore PH.

Oncogene. 1999 Jan 14;18(2):449-58.

27.

The structure of the site on adenovirus early region 1A responsible for binding to TATA-binding protein determined by NMR spectroscopy.

Molloy DP, Smith KJ, Milner AE, Gallimore PH, Grand RJ.

J Biol Chem. 1999 Feb 5;274(6):3503-12.

29.

Structural determinants present in the C-terminal binding protein binding site of adenovirus early region 1A proteins.

Molloy DP, Milner AE, Yakub IK, Chinnadurai G, Gallimore PH, Grand RJ.

J Biol Chem. 1998 Aug 14;273(33):20867-76.

30.

Human cells arrest in S phase in response to adenovirus 12 E1A.

Grand RJ, Ibrahim AP, Taylor AM, Milner AE, Gregory CD, Gallimore PH, Turnell AS.

Virology. 1998 May 10;244(2):330-42.

31.

Regeneration of the binding properties of adenovirus 12 early region 1A proteins after preparation under denaturing conditions.

Grand RJ, Gash L, Milner AE, Molloy DP, Szestak T, Turnell AS, Gallimore PH.

Virology. 1998 Apr 25;244(1):230-42.

33.

Adenovirus type 12 early region 1B 54K protein significantly extends the life span of normal mammalian cells in culture.

Gallimore PH, Lecane PS, Roberts S, Rookes SM, Grand RJ, Parkhill J.

J Virol. 1997 Sep;71(9):6629-40.

36.

The expression of MDM2 and other p53-regulated proteins in the tissues of the developing rat.

Ibrahim AP, Gallimore PH, Grand RJ.

Biochim Biophys Acta. 1997 Feb 28;1350(3):306-16.

PMID:
9061027
37.

Association of CDKN2A/p16INK4A with human head and neck keratinocyte replicative senescence: relationship of dysfunction to immortality and neoplasia.

Loughran O, Malliri A, Owens D, Gallimore PH, Stanley MA, Ozanne B, Frame MC, Parkinson EK.

Oncogene. 1996 Aug 1;13(3):561-8.

PMID:
8760298
38.

Control of p53 expression by adenovirus 12 early region 1A and early region 1B 54K proteins.

Grand RJ, Owen D, Rookes SM, Gallimore PH.

Virology. 1996 Apr 1;218(1):23-34.

39.

The high levels of p53 present in adenovirus early region 1-transformed human cells do not cause up-regulation of MDM2 expression.

Grand RJ, Lecane PS, Owen D, Grant ML, Roberts S, Levine AJ, Gallimore PH.

Virology. 1995 Jul 10;210(2):323-34.

40.

Regulation of neurite outgrowth from differentiated human neuroepithelial cells: a comparison of the activities of prothrombin and thrombin.

Turnell AS, Brant DP, Brown GR, Finney M, Gallimore PH, Kirk CJ, Pagliuca TR, Campbell CJ, Michell RH, Grand RJ.

Biochem J. 1995 Jun 15;308 ( Pt 3):965-73.

41.

The quaternary structure of the adenovirus 12 early region 1B 54K protein.

Grand RJ, Mustoe T, Roberts S, Gallimore PH.

Virology. 1995 Feb 20;207(1):255-9.

43.

Enhanced expression of p53 in human cells infected with mutant adenoviruses.

Grand RJ, Grant ML, Gallimore PH.

Virology. 1994 Sep;203(2):229-40.

PMID:
8053147
44.

Human papillomavirus type 1 E4 protein is a zinc-binding protein.

Roberts S, Ashmole I, Sheehan TM, Davies AH, Gallimore PH.

Virology. 1994 Aug 1;202(2):865-74.

PMID:
7518163
45.

Differential growth response to oestrogen of premalignant and malignant colonic cell lines.

Singh S, Paraskeva C, Gallimore PH, Sheppard MC, Langman MJ.

Anticancer Res. 1994 May-Jun;14(3A):1037-41.

PMID:
8074447
46.

Cutaneous and mucosal human papillomavirus E4 proteins form intermediate filament-like structures in epithelial cells.

Roberts S, Ashmole I, Johnson GD, Kreider JW, Gallimore PH.

Virology. 1993 Nov;197(1):176-87.

PMID:
8212552
47.
48.

Overexpression of wild-type p53 and c-Myc in human fetal cells transformed with adenovirus early region 1.

Grand RJ, Lecane PS, Roberts S, Grant ML, Lane DP, Young LS, Dawson CW, Gallimore PH.

Virology. 1993 Apr;193(2):579-91.

PMID:
8460477
49.

Vitronectin is the major serum protein essential for NGF-mediated neurite outgrowth from PC12 cells.

Grabham PW, Gallimore PH, Grand RJ.

Exp Cell Res. 1992 Oct;202(2):337-44.

PMID:
1383013
50.

Three transcriptionally distinct forms of Epstein-Barr virus latency in somatic cell hybrids: cell phenotype dependence of virus promoter usage.

Kerr BM, Lear AL, Rowe M, Croom-Carter D, Young LS, Rookes SM, Gallimore PH, Rickinson AB.

Virology. 1992 Mar;187(1):189-201.

PMID:
1310556

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