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Items: 1 to 50 of 192

1.

Crystal structure determination of Pseudomonas stutzeri A1501 endoglucanase Cel5A: the search for a molecular basis for glycosynthesis in GH5_5 enzymes.

Dutoit R, Delsaute M, Collet L, Vander Wauven C, Van Elder D, Berlemont R, Richel A, Galleni M, Bauvois C.

Acta Crystallogr D Struct Biol. 2019 Jun 1;75(Pt 6):605-615. doi: 10.1107/S2059798319007113. Epub 2019 Jun 6.

PMID:
31205022
2.

RNA Regulatory Networks as a Control of Stochasticity in Biological Systems.

Vandevenne M, Delmarcelle M, Galleni M.

Front Genet. 2019 May 7;10:403. doi: 10.3389/fgene.2019.00403. eCollection 2019. Review.

3.

Layer-by-layer assembly of enzyme-loaded halloysite nanotubes for the fabrication of highly active coatings.

Rouster P, Dondelinger M, Galleni M, Nysten B, Jonas AM, Glinel K.

Colloids Surf B Biointerfaces. 2019 Jun 1;178:508-514. doi: 10.1016/j.colsurfb.2019.03.046. Epub 2019 Mar 21.

PMID:
30928390
4.

Exploring the suitability of RanBP2-type Zinc Fingers for RNA-binding protein design.

De Franco S, Vandenameele J, Brans A, Verlaine O, Bendak K, Damblon C, Matagne A, Segal DJ, Galleni M, Mackay JP, Vandevenne M.

Sci Rep. 2019 Feb 21;9(1):2484. doi: 10.1038/s41598-019-38655-y.

5.

Der p 5 allergen from house dust mite: first epitope mapping of rabbit IgG blocking antibodies.

Lahiani S, Dumez ME, Bitam I, Galleni M.

New Microbes New Infect. 2018 Dec 7;27:69-74. doi: 10.1016/j.nmni.2018.11.009. eCollection 2019 Jan.

6.

Immunodominant IgE Epitopes of Der p 5 Allergen.

Lahiani S, Dumez ME, Bouaziz A, Djenouhat K, Khemili S, Bitam I, Gilis D, Galleni M.

Protein Pept Lett. 2018;25(11):1024-1034. doi: 10.2174/0929866525666181114144635.

PMID:
30430936
7.

Homology modeling and in vivo functional characterization of the zinc permeation pathway in a heavy metal P-type ATPase.

Lekeux G, Crowet JM, Nouet C, Joris M, Jadoul A, Bosman B, Carnol M, Motte P, Lins L, Galleni M, Hanikenne M.

J Exp Bot. 2019 Jan 1;70(1):329-341. doi: 10.1093/jxb/ery353.

8.

Understanding the Significance and Implications of Antibody Numbering and Antigen-Binding Surface/Residue Definition.

Dondelinger M, Filée P, Sauvage E, Quinting B, Muyldermans S, Galleni M, Vandevenne MS.

Front Immunol. 2018 Oct 16;9:2278. doi: 10.3389/fimmu.2018.02278. eCollection 2018. Review.

9.

Cross-Reactivity between Major IgE Epitopes of Family 5 Allergens from Dermatophagoides pteronyssinus and Blomia tropicalis.

Lahiani S, Dumez ME, Khemili S, Bitam I, Gilis D, Galleni M.

Int Arch Allergy Immunol. 2019;178(1):10-18. doi: 10.1159/000492871. Epub 2018 Oct 31.

PMID:
30380546
10.

di-Cysteine motifs in the C-terminus of plant HMA4 proteins confer nanomolar affinity for zinc and are essential for HMA4 function in vivo.

Lekeux G, Laurent C, Joris M, Jadoul A, Jiang D, Bosman B, Carnol M, Motte P, Xiao Z, Galleni M, Hanikenne M.

J Exp Bot. 2018 Nov 26;69(22):5547-5560. doi: 10.1093/jxb/ery311.

11.

A Kinetic Study of the Replacement by Site Saturation Mutagenesis of Residue 119 in NDM-1 Metallo-β-Lactamase.

Marcoccia F, Mercuri PS, Galleni M, Celenza G, Amicosante G, Perilli M.

Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e02541-17. doi: 10.1128/AAC.02541-17. Print 2018 Aug.

12.

Combinatorial Design of a Nanobody that Specifically Targets Structured RNAs.

Cawez F, Duray E, Hu Y, Vandenameele J, Romão E, Vincke C, Dumoulin M, Galleni M, Muyldermans S, Vandevenne M.

J Mol Biol. 2018 May 25;430(11):1652-1670. doi: 10.1016/j.jmb.2018.03.032. Epub 2018 Apr 11.

13.

P174E Substitution in GES-1 and GES-5 β-Lactamases Improves Catalytic Efficiency toward Carbapenems.

Piccirilli A, Mercuri PS, Galleni M, Aschi M, Matagne A, Amicosante G, Perilli M.

Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e01851-17. doi: 10.1128/AAC.01851-17. Print 2018 May.

14.

The Use of a β-lactamase-based Conductimetric Biosensor Assay to Detect Biomolecular Interactions.

Vandevenne M, Dondelinger M, Yunus S, Freischels A, Freischels R, Crasson O, Rhazi N, Bogaerts P, Galleni M, Filée P.

J Vis Exp. 2018 Feb 1;(132). doi: 10.3791/55414.

15.

Crystal structure and kinetic analysis of the class B3 di-zinc metallo-β-lactamase LRA-12 from an Alaskan soil metagenome.

Rodríguez MM, Herman R, Ghiglione B, Kerff F, D'Amico González G, Bouillenne F, Galleni M, Handelsman J, Charlier P, Gutkind G, Sauvage E, Power P.

PLoS One. 2017 Jul 27;12(7):e0182043. doi: 10.1371/journal.pone.0182043. eCollection 2017.

16.

Increased Antimicrobial Resistance in a Novel CMY-54 AmpC-Type Enzyme with a GluLeu217-218 Insertion in the Ω-Loop.

Pérez-Llarena FJ, Vázquez-Ucha JC, Kerff F, Zamorano L, Miró E, Cabral MP, Fleites A, Lantero M, Martínez-Martínez L, Oliver A, Galleni M, Navarro F, Beceiro A, Bou G.

Microb Drug Resist. 2018 Jun;24(5):527-533. doi: 10.1089/mdr.2017.0017. Epub 2017 Jun 30.

PMID:
28665771
17.

Profiling the Extended Cleavage Specificity of the House Dust Mite Protease Allergens Der p 1, Der p 3 and Der p 6 for the Prediction of New Cell Surface Protein Substrates.

Jacquet A, Campisi V, Szpakowska M, Dumez ME, Galleni M, Chevigné A.

Int J Mol Sci. 2017 Jun 27;18(7). pii: E1373. doi: 10.3390/ijms18071373.

18.

Human Chitotriosidase: Catalytic Domain or Carbohydrate Binding Module, Who's Leading HCHT's Biological Function.

Crasson O, Courtade G, Léonard RR, Aachmann FL, Legrand F, Parente R, Baurain D, Galleni M, Sørlie M, Vandevenne M.

Sci Rep. 2017 Jun 5;7(1):2768. doi: 10.1038/s41598-017-02382-z.

19.

The Lys-Asp-Tyr Triad within the Mite Allergen Der p 1 Propeptide Is a Critical Structural Element for the pH-Dependent Initiation of the Protease Maturation.

Chevigné A, Campizi V, Szpakowska M, Bourry D, Dumez ME, Martins JC, Matagne A, Galleni M, Jacquet A.

Int J Mol Sci. 2017 May 20;18(5). pii: E1087. doi: 10.3390/ijms18051087.

20.

1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-β-lactamases.

Sevaille L, Gavara L, Bebrone C, De Luca F, Nauton L, Achard M, Mercuri P, Tanfoni S, Borgianni L, Guyon C, Lonjon P, Turan-Zitouni G, Dzieciolowski J, Becker K, Bénard L, Condon C, Maillard L, Martinez J, Frère JM, Dideberg O, Galleni M, Docquier JD, Hernandez JF.

ChemMedChem. 2017 Jun 21;12(12):972-985. doi: 10.1002/cmdc.201700186. Epub 2017 Jun 12.

PMID:
28505394
21.

Impact of Mutations at Arg220 and Thr237 in PER-2 β-Lactamase on Conformation, Activity, and Susceptibility to Inhibitors.

Ruggiero M, Curto L, Brunetti F, Sauvage E, Galleni M, Power P, Gutkind G.

Antimicrob Agents Chemother. 2017 May 24;61(6). pii: e02193-16. doi: 10.1128/AAC.02193-16. Print 2017 Jun.

22.

Kinetic Studies on CphA Mutants Reveal the Role of the P158-P172 Loop in Activity versus Carbapenems.

Bottoni C, Perilli M, Marcoccia F, Piccirilli A, Pellegrini C, Colapietro M, Sabatini A, Celenza G, Kerff F, Amicosante G, Galleni M, Mercuri PS.

Antimicrob Agents Chemother. 2016 Apr 22;60(5):3123-6. doi: 10.1128/AAC.01703-15. Print 2016 May.

23.

Kinetic Study of Laboratory Mutants of NDM-1 Metallo-β-Lactamase and the Importance of an Isoleucine at Position 35.

Marcoccia F, Bottoni C, Sabatini A, Colapietro M, Mercuri PS, Galleni M, Kerff F, Matagne A, Celenza G, Amicosante G, Perilli M.

Antimicrob Agents Chemother. 2016 Mar 25;60(4):2366-72. doi: 10.1128/AAC.00531-15. Print 2016 Apr.

24.

Metal binding to the N-terminal cytoplasmic domain of the PIB ATPase HMA4 is required for metal transport in Arabidopsis.

Laurent C, Lekeux G, Ukuwela AA, Xiao Z, Charlier JB, Bosman B, Carnol M, Motte P, Damblon C, Galleni M, Hanikenne M.

Plant Mol Biol. 2016 Mar;90(4-5):453-66. doi: 10.1007/s11103-016-0429-z. Epub 2016 Jan 21.

25.

Kinetics of the Interaction between BAL29880 and LK157 and the Class C β-Lactamase CHE-1.

Fernea A, Galleni M, Frère JM.

Antimicrob Agents Chemother. 2016 Jan 4;60(3):1747-50. doi: 10.1128/AAC.02062-15.

26.

Generation of a soluble recombinant trimeric form of bovine CD40L and its potential use as a vaccine adjuvant in cows.

Pujol J, Bouillenne F, Farnir F, Dufrasne I, Mainil J, Galleni M, Lekeux P, Bureau F, Fiévez L.

Vet Immunol Immunopathol. 2015 Nov 15;168(1-2):1-13. doi: 10.1016/j.vetimm.2015.09.011. Epub 2015 Sep 28.

PMID:
26553560
27.

Structural and Kinetic Insights into the "Ceftazidimase" Behavior of the Extended-Spectrum β-Lactamase CTX-M-96.

Ghiglione B, Rodríguez MM, Herman R, Curto L, Dropa M, Bouillenne F, Kerff F, Galleni M, Charlier P, Gutkind G, Sauvage E, Power P.

Biochemistry. 2015 Aug 18;54(32):5072-82. doi: 10.1021/acs.biochem.5b00313. Epub 2015 Aug 10.

PMID:
26228623
28.

Synthesis and Physicochemical Characterization of D-Tagatose-1-Phosphate: The Substrate of the Tagatose-1-Phosphate Kinase in the Phosphotransferase System-Mediated D-Tagatose Catabolic Pathway of Bacillus licheniformis.

Van der Heiden E, Delmarcelle M, Simon P, Counson M, Galleni M, Freedberg DI, Thompson J, Joris B, Battistel MD.

J Mol Microbiol Biotechnol. 2015;25(2-3):106-19. doi: 10.1159/000370115. Epub 2015 Jul 9.

29.

Enzymatic functionalization of a nanobody using protein insertion technology.

Crasson O, Rhazi N, Jacquin O, Freichels A, Jérôme C, Ruth N, Galleni M, Filée P, Vandevenne M.

Protein Eng Des Sel. 2015 Oct;28(10):451-60. doi: 10.1093/protein/gzv020. Epub 2015 Apr 6.

PMID:
25852149
30.

Development of recombinant stable house dust mite allergen Der p 3 molecules for component-resolved diagnosis and specific immunotherapy.

Bouaziz A, Walgraffe D, Bouillot C, Herman J, Foguenne J, Gothot A, Louis R, Hentges F, Jacquet A, Mailleux AC, Chevigné A, Galleni M, Adam E, Dumez ME.

Clin Exp Allergy. 2015 Apr;45(4):823-34. doi: 10.1111/cea.12452.

PMID:
25406386
31.

Kinetics of the interaction between avibactam and the CHE-1 class C β-lactamase.

Fernea A, Galleni M, Frère JM.

J Antimicrob Chemother. 2015 Mar;70(3):951-3. doi: 10.1093/jac/dku442. Epub 2014 Oct 31. No abstract available.

PMID:
25362576
32.

Genetic and kinetic characterization of the novel AmpC β-lactamases DHA-6 and DHA-7.

Pérez-Llarena FJ, Zamorano L, Kerff F, Beceiro A, García P, Miró E, Larrosa N, Gómez-Bertomeu F, Méndez JA, González-López JJ, Oliver A, Galleni M, Navarro F, Bou G.

Antimicrob Agents Chemother. 2014 Nov;58(11):6544-9. doi: 10.1128/AAC.03144-14. Epub 2014 Aug 18.

33.

Crystal structure of the extended-spectrum β-lactamase PER-2 and insights into the role of specific residues in the interaction with β-lactams and β-lactamase inhibitors.

Ruggiero M, Kerff F, Herman R, Sapunaric F, Galleni M, Gutkind G, Charlier P, Sauvage E, Power P.

Antimicrob Agents Chemother. 2014 Oct;58(10):5994-6002. doi: 10.1128/AAC.00089-14. Epub 2014 Jul 28.

34.

Study of a Natural Mutant SHV-Type β -Lactamase, SHV-104, from Klebsiella pneumoniae.

Ben Achour N, Belhadj O, Galleni M, Ben Moussa M, Mercuri PS.

Int J Microbiol. 2014;2014:548656. doi: 10.1155/2014/548656. Epub 2014 May 13.

35.

New mutations in ADC-type β-lactamases from Acinetobacter spp. affect cefoxitin and ceftazidime hydrolysis.

Pérez A, Pérez-Llarena FJ, García P, Kerff F, Beceiro A, Galleni M, Bou G.

J Antimicrob Chemother. 2014 Sep;69(9):2407-11. doi: 10.1093/jac/dku163. Epub 2014 May 20.

PMID:
24845871
36.

Orchestration of an uncommon maturation cascade of the house dust mite protease allergen quartet.

Dumez ME, Herman J, Campizi V, Galleni M, Jacquet A, Chevigné A.

Front Immunol. 2014 Mar 31;5:138. doi: 10.3389/fimmu.2014.00138. eCollection 2014. Review.

37.

Der p 1 is the primary activator of Der p 3, Der p 6 and Der p 9 the proteolytic allergens produced by the house dust mite Dermatophagoides pteronyssinus.

Herman J, Thelen N, Smargiasso N, Mailleux AC, Luxen A, Cloes M, De Pauw E, Chevigné A, Galleni M, Dumez ME.

Biochim Biophys Acta. 2014 Mar;1840(3):1117-24. doi: 10.1016/j.bbagen.2013.11.017. Epub 2013 Nov 27.

38.

The proline-rich motif of the proDer p 3 allergen propeptide is crucial for protease-protease interaction.

Dumez ME, Herman J, Campisi V, Bouaziz A, Rosu F, Luxen A, Vandenberghe I, de Pauw E, Frère JM, Matagne A, Chevigné A, Galleni M.

PLoS One. 2013 Sep 20;8(9):e68014. doi: 10.1371/journal.pone.0068014. eCollection 2013.

39.

Class A β-lactamases as versatile scaffolds to create hybrid enzymes: applications from basic research to medicine.

Huynen C, Filée P, Matagne A, Galleni M, Dumoulin M.

Biomed Res Int. 2013;2013:827621. doi: 10.1155/2013/827621. Epub 2013 Aug 28. Review.

40.

Three-dimensional structure of RBcel1, a metagenome-derived psychrotolerant family GH5 endoglucanase.

Delsaute M, Berlemont R, Dehareng D, Van Elder D, Galleni M, Bauvois C.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Aug;69(Pt 8):828-33. doi: 10.1107/S1744309113014565. Epub 2013 Jul 26.

41.

Novel organic solvent-tolerant esterase isolated by metagenomics: insights into the lipase/esterase classification.

Berlemont R, Spee O, Delsaute M, Lara Y, Schuldes J, Simon C, Power P, Daniel R, Galleni M.

Rev Argent Microbiol. 2013 Jan-Mar;45(1):3-12.

42.

A pathway closely related to the (D)-tagatose pathway of gram-negative enterobacteria identified in the gram-positive bacterium Bacillus licheniformis.

Van der Heiden E, Delmarcelle M, Lebrun S, Freichels R, Brans A, Vastenavond CM, Galleni M, Joris B.

Appl Environ Microbiol. 2013 Jun;79(11):3511-5. doi: 10.1128/AEM.03918-12. Epub 2013 Mar 22.

43.

Allosteric inhibition of VIM metallo-β-lactamases by a camelid nanobody.

Sohier JS, Laurent C, Chevigné A, Pardon E, Srinivasan V, Wernery U, Lassaux P, Steyaert J, Galleni M.

Biochem J. 2013 Mar 15;450(3):477-86. doi: 10.1042/BJ20121305.

44.

Novel Cold-Adapted Esterase MHlip from an Antarctic Soil Metagenome.

Berlemont R, Jacquin O, Delsaute M, La Salla M, Georis J, Verté F, Galleni M, Power P.

Biology (Basel). 2013 Jan 25;2(1):177-88. doi: 10.3390/biology2010177.

45.

R164H and V240H replacements by site-directed mutagenesis of TEM-149 extended-spectrum β-lactamase: kinetic analysis of TEM-149H240 and TEM-149H164-H240 laboratory mutants.

Perilli M, Celenza G, Mercuri PS, Galleni M, Pellegrini C, Segatore B, Amicosante G.

Antimicrob Agents Chemother. 2013 Feb;57(2):1047-9. doi: 10.1128/AAC.01268-12. Epub 2012 Nov 26.

46.

Kinetic and crystallographic studies of extended-spectrum GES-11, GES-12, and GES-14 β-lactamases.

Delbrück H, Bogaerts P, Kupper MB, Rezende de Castro R, Bennink S, Glupczynski Y, Galleni M, Hoffmann KM, Bebrone C.

Antimicrob Agents Chemother. 2012 Nov;56(11):5618-25. doi: 10.1128/AAC.01272-12. Epub 2012 Aug 20.

47.

Novel fragments of clavulanate observed in the structure of the class A β-lactamase from Bacillus licheniformis BS3.

Power P, Mercuri P, Herman R, Kerff F, Gutkind G, Dive G, Galleni M, Charlier P, Sauvage E.

J Antimicrob Chemother. 2012 Oct;67(10):2379-87. doi: 10.1093/jac/dks231. Epub 2012 Jul 6.

PMID:
22773738
48.

Inhibition of the keratinolytic subtilisin protease Sub3 from Microsporum canis by its propeptide (proSub3) and evaluation of the capacity of proSub3 to inhibit fungal adherence to feline epidermis.

Baldo A, Chevigné A, Dumez ME, Mathy A, Power P, Tabart J, Cambier L, Galleni M, Mignon B.

Vet Microbiol. 2012 Oct 12;159(3-4):479-84. doi: 10.1016/j.vetmic.2012.04.041. Epub 2012 May 8.

PMID:
22633172
49.

Synthesis, crystal structures and electronic properties of isomers of chloro-pyridinylvinyl-1H-indoles.

Moineaux L, Laurent S, Reniers J, Dolušić E, Galleni M, Frère JM, Masereel B, Frédérick R, Wouters J.

Eur J Med Chem. 2012 Aug;54:95-102. doi: 10.1016/j.ejmech.2012.04.033. Epub 2012 May 3.

PMID:
22626654
50.

Amyloid-like fibril formation by polyQ proteins: a critical balance between the polyQ length and the constraints imposed by the host protein.

Scarafone N, Pain C, Fratamico A, Gaspard G, Yilmaz N, Filée P, Galleni M, Matagne A, Dumoulin M.

PLoS One. 2012;7(3):e31253. doi: 10.1371/journal.pone.0031253. Epub 2012 Mar 9.

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