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Items: 1 to 50 of 112

1.

Targeting bromodomain-containing protein 4 (BRD4) inhibits MYC expression in colorectal cancer cells.

Otto C, Schmidt S, Kastner C, Denk S, Kettler J, Müller N, Germer CT, Wolf E, Gallant P, Wiegering A.

Neoplasia. 2019 Nov;21(11):1110-1120. doi: 10.1016/j.neo.2019.10.003. Epub 2019 Nov 14.

2.

MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation.

Baluapuri A, Hofstetter J, Dudvarski Stankovic N, Endres T, Bhandare P, Vos SM, Adhikari B, Schwarz JD, Narain A, Vogt M, Wang SY, Düster R, Jung LA, Vanselow JT, Wiegering A, Geyer M, Maric HM, Gallant P, Walz S, Schlosser A, Cramer P, Eilers M, Wolf E.

Mol Cell. 2019 May 16;74(4):674-687.e11. doi: 10.1016/j.molcel.2019.02.031. Epub 2019 Mar 27.

3.

PAF1 complex component Leo1 helps recruit Drosophila Myc to promoters.

Gerlach JM, Furrer M, Gallant M, Birkel D, Baluapuri A, Wolf E, Gallant P.

Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9224-E9232. doi: 10.1073/pnas.1705816114. Epub 2017 Oct 16.

4.

Multiplanar lumbopelvic control in patients with low back pain: is multiplanar assessment better than single plane assessment in discriminating between patients and healthy controls?

Nelson-Wong E, Gallant P, Alexander S, Dehmer K, Ingvalson S, McClenahan B, Piatte A, Poupore K, Davis AM.

J Man Manip Ther. 2016 Feb;24(1):45-50. doi: 10.1179/2042618614Y.0000000078.

5.

snoRNAs are a novel class of biologically relevant Myc targets.

Herter EK, Stauch M, Gallant M, Wolf E, Raabe T, Gallant P.

BMC Biol. 2015 Apr 16;13:25. doi: 10.1186/s12915-015-0132-6.

6.

Syntaxin 4 is concentrated on plasma membrane of astrocytes.

Tao-Cheng JH, Pham A, Yang Y, Winters CA, Gallant PE, Reese TS.

Neuroscience. 2015 Feb 12;286:264-71. doi: 10.1016/j.neuroscience.2014.11.054. Epub 2014 Dec 5.

7.

Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink.

Spinelli L, Botwicz M, Zolek N, Kacprzak M, Milej D, Sawosz P, Liebert A, Weigel U, Durduran T, Foschum F, Kienle A, Baribeau F, Leclair S, Bouchard JP, Noiseux I, Gallant P, Mermut O, Farina A, Pifferi A, Torricelli A, Cubeddu R, Ho HC, Mazurenka M, Wabnitz H, Klauenberg K, Bodnar O, Elster C, Bénazech-Lavoué M, Bérubé-Lauzière Y, Lesage F, Khoptyar D, Subash AA, Andersson-Engels S, Di Ninni P, Martelli F, Zaccanti G.

Biomed Opt Express. 2014 Jun 4;5(7):2037-53. doi: 10.1364/BOE.5.002037. eCollection 2014 Jul 1.

8.

Drosophila mbm is a nucleolar myc and casein kinase 2 target required for ribosome biogenesis and cell growth of central brain neuroblasts.

Hovhanyan A, Herter EK, Pfannstiel J, Gallant P, Raabe T.

Mol Cell Biol. 2014 May;34(10):1878-91. doi: 10.1128/MCB.00658-13. Epub 2014 Mar 10.

9.

Homer is concentrated at the postsynaptic density and does not redistribute after acute synaptic stimulation.

Tao-Cheng JH, Thein S, Yang Y, Reese TS, Gallant PE.

Neuroscience. 2014 Apr 25;266:80-90. doi: 10.1016/j.neuroscience.2014.01.066. Epub 2014 Feb 12.

10.

Towards a bimodal proximity sensor for in situ neurovascular bundle detection during dental implant surgery.

Weber JR, Baribeau F, Grenier P, Emond F, Dubois S, Duchesne F, Girard M, Pope T, Gallant P, Mermut O, Moghadam HG.

Biomed Opt Express. 2013 Dec 2;5(1):16-30. doi: 10.1364/BOE.5.000016. eCollection 2013 Dec 2.

11.

Myc function in Drosophila.

Gallant P.

Cold Spring Harb Perspect Med. 2013 Oct 1;3(10):a014324. doi: 10.1101/cshperspect.a014324. Review.

12.

Neuromuscular strategies for lumbopelvic control during frontal and sagittal plane movement challenges differ between people with and without low back pain.

Nelson-Wong E, Poupore K, Ingvalson S, Dehmer K, Piatte A, Alexander S, Gallant P, McClenahan B, Davis AM.

J Electromyogr Kinesiol. 2013 Dec;23(6):1317-24. doi: 10.1016/j.jelekin.2013.08.011. Epub 2013 Sep 14.

PMID:
24080287
13.

In vivo detection of human TRPV6-rich tumors with anti-cancer peptides derived from soricidin.

Bowen CV, DeBay D, Ewart HS, Gallant P, Gormley S, Ilenchuk TT, Iqbal U, Lutes T, Martina M, Mealing G, Merkley N, Sperker S, Moreno MJ, Rice C, Syvitski RT, Stewart JM.

PLoS One. 2013;8(3):e58866. doi: 10.1371/journal.pone.0058866. Epub 2013 Mar 15.

14.

Monogalactosyldiacylglycerols, potent nitric oxide inhibitors from the marine microalga Tetraselmis chui.

Banskota AH, Gallant P, Stefanova R, Melanson R, O'Leary SJ.

Nat Prod Res. 2013;27(12):1084-90. doi: 10.1080/14786419.2012.717285. Epub 2012 Sep 14.

PMID:
22973805
15.

Nitric oxide inhibitory activity of monogalactosylmonoacylglycerols from a freshwater microalgae Chlorella sorokiniana.

Banskota AH, Stefanova R, Gallant P, Osborne JA, Melanson R, O'Leary SJ.

Nat Prod Res. 2013;27(11):1028-31. doi: 10.1080/14786419.2012.696255. Epub 2012 Jun 18.

PMID:
22703524
16.

Investigations into the toxicology of spirolides, a group of marine phycotoxins.

Munday R, Quilliam MA, LeBlanc P, Lewis N, Gallant P, Sperker SA, Ewart HS, MacKinnon SL.

Toxins (Basel). 2012 Jan;4(1):1-14. doi: 10.3390/toxins4010001. Epub 2011 Dec 30.

17.

Discovery of 2,4-bis-arylamino-1,3-pyrimidines as insulin-like growth factor-1 receptor (IGF-1R) inhibitors.

Buchanan JL, Newcomb JR, Carney DP, Chaffee SC, Chai L, Cupples R, Epstein LF, Gallant P, Gu Y, Harmange JC, Hodge K, Houk BE, Huang X, Jona J, Joseph S, Jun HT, Kumar R, Li C, Lu J, Menges T, Morrison MJ, Novak PM, van der Plas S, Radinsky R, Rose PE, Sawant S, Sun JR, Surapaneni S, Turci SM, Xu K, Yanez E, Zhao H, Zhu X.

Bioorg Med Chem Lett. 2011 Apr 15;21(8):2394-9. doi: 10.1016/j.bmcl.2011.02.075. Epub 2011 Feb 23.

PMID:
21414779
18.

Myc Function in Drosophila.

Bellosta P, Gallant P.

Genes Cancer. 2010 Jun 1;1(6):542-546.

19.

Drosophila Myc interacts with host cell factor (dHCF) to activate transcription and control growth.

Furrer M, Balbi M, Albarca-Aguilera M, Gallant M, Herr W, Gallant P.

J Biol Chem. 2010 Dec 17;285(51):39623-36. doi: 10.1074/jbc.M110.140467. Epub 2010 Oct 11.

20.

Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor.

Cee VJ, Schenkel LB, Hodous BL, Deak HL, Nguyen HN, Olivieri PR, Romero K, Bak A, Be X, Bellon S, Bush TL, Cheng AC, Chung G, Coats S, Eden PM, Hanestad K, Gallant PL, Gu Y, Huang X, Kendall RL, Lin MH, Morrison MJ, Patel VF, Radinsky R, Rose PE, Ross S, Sun JR, Tang J, Zhao H, Payton M, Geuns-Meyer SD.

J Med Chem. 2010 Sep 9;53(17):6368-77. doi: 10.1021/jm100394y.

PMID:
20684549
21.

Flower dooms cells to death.

Gallant P.

Dev Cell. 2010 Jun 15;18(6):882-3. doi: 10.1016/j.devcel.2010.05.019.

22.

Activity induced changes in the distribution of Shanks at hippocampal synapses.

Tao-Cheng JH, Dosemeci A, Gallant PE, Smith C, Reese T.

Neuroscience. 2010 Jun 16;168(1):11-7. doi: 10.1016/j.neuroscience.2010.03.041. Epub 2010 Mar 25.

23.

Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein.

Lin X, Parisiadou L, Gu XL, Wang L, Shim H, Sun L, Xie C, Long CX, Yang WJ, Ding J, Chen ZZ, Gallant PE, Tao-Cheng JH, Rudow G, Troncoso JC, Liu Z, Li Z, Cai H.

Neuron. 2009 Dec 24;64(6):807-27. doi: 10.1016/j.neuron.2009.11.006.

24.

Molecular imaging of the translocator protein (TSPO) in a pre-clinical model of breast cancer.

Wyatt SK, Manning HC, Bai M, Bailey SN, Gallant P, Ma G, McIntosh L, Bornhop DJ.

Mol Imaging Biol. 2010 Jun;12(3):349-58. doi: 10.1007/s11307-009-0270-8. Epub 2009 Dec 1.

25.

Myc's secret life without Max.

Gallant P, Steiger D.

Cell Cycle. 2009 Dec;8(23):3848-53. Epub 2009 Dec 15. Review.

PMID:
19887915
26.

Drosophila Myc.

Gallant P.

Adv Cancer Res. 2009;103:111-44. doi: 10.1016/S0065-230X(09)03005-X. Review.

27.

The conserved Myc box 2 and Myc box 3 regions are important, but not essential, for Myc function in vivo.

Schwinkendorf D, Gallant P.

Gene. 2009 May 1;436(1-2):90-100. doi: 10.1016/j.gene.2009.02.009. Epub 2009 Feb 24.

PMID:
19248823
28.

Rapid turnover of spinules at synaptic terminals.

Tao-Cheng JH, Dosemeci A, Gallant PE, Miller S, Galbraith JA, Winters CA, Azzam R, Reese TS.

Neuroscience. 2009 Apr 21;160(1):42-50. doi: 10.1016/j.neuroscience.2009.02.031. Epub 2009 Feb 25.

29.

The Clinical Scholar Model: Evidence-based practice at the bedside.

Honess C, Gallant P, Keane K.

Nurs Clin North Am. 2009 Mar;44(1):117-30, xii. doi: 10.1016/j.cnur.2008.10.004. Review.

PMID:
19167554
30.

Max-independent functions of Myc in Drosophila melanogaster.

Steiger D, Furrer M, Schwinkendorf D, Gallant P.

Nat Genet. 2008 Sep;40(9):1084-91. doi: 10.1038/ng.178.

PMID:
19165923
31.

The use of magnetic field effects on photosensitizer luminescence as a novel probe for optical monitoring of oxygen in photodynamic therapy.

Mermut O, Diamond KR, Cormier JF, Gallant P, Hô N, Leclair S, Marois JS, Noiseux I, Morin JF, Patterson MS, Vernon ML.

Phys Med Biol. 2009 Jan 7;54(1):1-16. doi: 10.1088/0031-9155/54/1/001. Epub 2008 Dec 5.

PMID:
19060362
32.

Effect of liposomal confinement on photothermal and photo-oximetric fluorescence lifetimes of photosensitizers with varying hydrophilicity.

Mermut O, Noiseux I, Bouchard JP, Cormier JF, Desroches P, Fortin M, Gallant P, Leclair S, Vernon ML, Diamond KR, Patterson MS.

J Biomed Opt. 2008 Jul-Aug;13(4):041314. doi: 10.1117/1.2952298.

33.

Effect of liposomal confinement on photochemical properties of photosensitizers with varying hydrophilicity.

Noiseux I, Mermut O, Bouchard JP, Cormier JF, Desroches P, Fortin M, Gallant P, Leclair S, Vernon ML, Diamond KR, Patterson MS.

J Biomed Opt. 2008 Jul-Aug;13(4):041313. doi: 10.1117/1.2950309.

34.

Getting started : an overview on raising and handling Drosophila.

Stocker H, Gallant P.

Methods Mol Biol. 2008;420:27-44. doi: 10.1007/978-1-59745-583-1_2. Review.

PMID:
18641939
35.

Pioneering a new role: the beginning, current practice and future of the Clinical Nurse Leader.

Poulin-Tabor D, Quirk RL, Wilson L, Orff S, Gallant P, Swan N, Manchester N.

J Nurs Manag. 2008 Jul;16(5):623-8. doi: 10.1111/j.1365-2834.2008.00905.x.

PMID:
18558933
36.

Glycemic control and reduction of deep sternal wound infection rates: a multidisciplinary approach.

Kramer R, Groom R, Weldner D, Gallant P, Heyl B, Knapp R, Arnold A.

Arch Surg. 2008 May;143(5):451-6. doi: 10.1001/archsurg.143.5.451.

PMID:
18490552
37.

Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation.

DiMauro EF, Newcomb J, Nunes JJ, Bemis JE, Boucher C, Chai L, Chaffee SC, Deak HL, Epstein LF, Faust T, Gallant P, Gore A, Gu Y, Henkle B, Hsieh F, Huang X, Kim JL, Lee JH, Martin MW, McGowan DC, Metz D, Mohn D, Morgenstern KA, Oliveira-dos-Santos A, Patel VF, Powers D, Rose PE, Schneider S, Tomlinson SA, Tudor YY, Turci SM, Welcher AA, Zhao H, Zhu L, Zhu X.

J Med Chem. 2008 Mar 27;51(6):1681-94. doi: 10.1021/jm7010996. Epub 2008 Mar 6.

PMID:
18321037
38.

Structure-based design of novel 2-amino-6-phenyl-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as potent and orally active inhibitors of lymphocyte specific kinase (Lck): synthesis, SAR, and in vivo anti-inflammatory activity.

Martin MW, Newcomb J, Nunes JJ, Boucher C, Chai L, Epstein LF, Faust T, Flores S, Gallant P, Gore A, Gu Y, Hsieh F, Huang X, Kim JL, Middleton S, Morgenstern K, Oliveira-dos-Santos A, Patel VF, Powers D, Rose P, Tudor Y, Turci SM, Welcher AA, Zack D, Zhao H, Zhu L, Zhu X, Ghiron C, Ermann M, Johnston D, Saluste CG.

J Med Chem. 2008 Mar 27;51(6):1637-48. doi: 10.1021/jm701095m. Epub 2008 Feb 16.

PMID:
18278858
39.

Induction of apoptosis by Drosophila Myc.

Montero L, Müller N, Gallant P.

Genesis. 2008 Feb;46(2):104-11. doi: 10.1002/dvg.20373.

40.

A quantitative analysis of kinase inhibitor selectivity.

Karaman MW, Herrgard S, Treiber DK, Gallant P, Atteridge CE, Campbell BT, Chan KW, Ciceri P, Davis MI, Edeen PT, Faraoni R, Floyd M, Hunt JP, Lockhart DJ, Milanov ZV, Morrison MJ, Pallares G, Patel HK, Pritchard S, Wodicka LM, Zarrinkar PP.

Nat Biotechnol. 2008 Jan;26(1):127-32. doi: 10.1038/nbt1358.

PMID:
18183025
41.

Canada's first universal varicella immunization program: Lessons from Prince Edward Island.

Sweet L, Gallant P, Morris M, Halperin SA.

Can J Infect Dis. 2003 Jan;14(1):41-4.

42.

N-(3-(phenylcarbamoyl)arylpyrimidine)-5-carboxamides as potent and selective inhibitors of Lck: structure, synthesis and SAR.

Deak HL, Newcomb JR, Nunes JJ, Boucher C, Cheng AC, DiMauro EF, Epstein LF, Gallant P, Hodous BL, Huang X, Lee JH, Patel VF, Schneider S, Turci SM, Zhu X.

Bioorg Med Chem Lett. 2008 Feb 1;18(3):1172-6. Epub 2007 Dec 5.

PMID:
18083554
43.

Design, synthesis, and evaluation of orally active benzimidazoles and benzoxazoles as vascular endothelial growth factor-2 receptor tyrosine kinase inhibitors.

Potashman MH, Bready J, Coxon A, DeMelfi TM Jr, DiPietro L, Doerr N, Elbaum D, Estrada J, Gallant P, Germain J, Gu Y, Harmange JC, Kaufman SA, Kendall R, Kim JL, Kumar GN, Long AM, Neervannan S, Patel VF, Polverino A, Rose P, Plas Sv, Whittington D, Zanon R, Zhao H.

J Med Chem. 2007 Sep 6;50(18):4351-73. Epub 2007 Aug 15. Erratum in: J Med Chem. 2008 Feb 14;51(3):699.

PMID:
17696416
44.

In vivo optical imaging of acute myeloid leukemia by green fluorescent protein: time-domain autofluorescence decoupling, fluorophore quantification, and localization.

McCormack E, Micklem DR, Pindard LE, Silden E, Gallant P, Belenkov A, Lorens JB, Gjertsen BT.

Mol Imaging. 2007 May-Jun;6(3):193-204.

PMID:
17532885
46.

Sensitivity characterization of a time-domain fluorescence imager: eXplore Optix.

Ma G, Gallant P, McIntosh L.

Appl Opt. 2007 Apr 1;46(10):1650-7.

PMID:
17356607
47.

Synthesis, structural analysis, and SAR studies of triazine derivatives as potent, selective Tie-2 inhibitors.

Hodous BL, Geuns-Meyer SD, Hughes PE, Albrecht BK, Bellon S, Caenepeel S, Cee VJ, Chaffee SC, Emery M, Fretland J, Gallant P, Gu Y, Johnson RE, Kim JL, Long AM, Morrison M, Olivieri PR, Patel VF, Polverino A, Rose P, Wang L, Zhao H.

Bioorg Med Chem Lett. 2007 May 15;17(10):2886-9. Epub 2007 Feb 25.

PMID:
17350837
48.

Control of transcription by Pontin and Reptin.

Gallant P.

Trends Cell Biol. 2007 Apr;17(4):187-92. Epub 2007 Feb 22. Review.

49.

Structural changes at synapses after delayed perfusion fixation in different regions of the mouse brain.

Tao-Cheng JH, Gallant PE, Brightman MW, Dosemeci A, Reese TS.

J Comp Neurol. 2007 Apr 10;501(5):731-40.

PMID:
17299754
50.

Alkynylpyrimidine amide derivatives as potent, selective, and orally active inhibitors of Tie-2 kinase.

Cee VJ, Albrecht BK, Geuns-Meyer S, Hughes P, Bellon S, Bready J, Caenepeel S, Chaffee SC, Coxon A, Emery M, Fretland J, Gallant P, Gu Y, Hodous BL, Hoffman D, Johnson RE, Kendall R, Kim JL, Long AM, McGowan D, Morrison M, Olivieri PR, Patel VF, Polverino A, Powers D, Rose P, Wang L, Zhao H.

J Med Chem. 2007 Feb 22;50(4):627-40. Epub 2007 Jan 25.

PMID:
17253679

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