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A Compact, High-Accuracy Cas9 with a Dinucleotide PAM for In Vivo Genome Editing.

Edraki A, Mir A, Ibraheim R, Gainetdinov I, Yoon Y, Song CQ, Cao Y, Gallant J, Xue W, Rivera-Pérez JA, Sontheimer EJ.

Mol Cell. 2018 Dec 18. pii: S1097-2765(18)31033-5. doi: 10.1016/j.molcel.2018.12.003. [Epub ahead of print]


Human Scene-Selective Areas Represent 3D Configurations of Surfaces.

Lescroart MD, Gallant JL.

Neuron. 2019 Jan 2;101(1):178-192.e7. doi: 10.1016/j.neuron.2018.11.004. Epub 2018 Nov 26.


Update on sinus disease in children with cystic fibrosis: advances in treatment modalities, microbiology, and health-related quality-of-life instruments.

Gallant JN, Mitchell MB, Virgin FW.

Curr Opin Otolaryngol Head Neck Surg. 2018 Dec;26(6):417-420. doi: 10.1097/MOO.0000000000000495.


Electrostatic Tuning of a Potassium Channel in Electric Fish.

Swapna I, Ghezzi A, York JM, Markham MR, Halling DB, Lu Y, Gallant JR, Zakon HH.

Curr Biol. 2018 Jul 9;28(13):2094-2102.e5. doi: 10.1016/j.cub.2018.05.012. Epub 2018 Jun 21.


Psychosocial Difficulties in Adolescent Idiopathic Scoliosis: Body Image, Eating Behaviors, and Mood Disorders.

Gallant JN, Morgan CD, Stoklosa JB, Gannon SR, Shannon CN, Bonfield CM.

World Neurosurg. 2018 Aug;116:421-432.e1. doi: 10.1016/j.wneu.2018.05.104. Epub 2018 May 23. Review.


The role of natural selection in shaping genetic variation in a promising Chagas disease drug target: Trypanosoma cruzi trans-sialidase.

Gallant JP, Lima-Cordón RA, Justi SA, Monroy MC, Viola T, Stevens L.

Infect Genet Evol. 2018 Aug;62:151-159. doi: 10.1016/j.meegid.2018.04.025. Epub 2018 Apr 21.


A week-48 randomized phase-3 trial of darunavir/cobicistat/emtricitabine/tenofovir alafenamide in treatment-naive HIV-1 patients.

Eron JJ, Orkin C, Gallant J, Molina JM, Negredo E, Antinori A, Mills A, Reynes J, Van Landuyt E, Lathouwers E, Hufkens V, Jezorwski J, Vanveggel S, Opsomer M; AMBER study group.

AIDS. 2018 Jul 17;32(11):1431-1442. doi: 10.1097/QAD.0000000000001817.


How Should Trainee Autonomy and Oversight Be Managed in the Setting of Overlapping Surgery?

Gallant JN, Langerman A.

AMA J Ethics. 2018 Apr 1;20(4):342-348. doi: 10.1001/journalofethics.2018.20.4.ecas3-1804.


Nasal saline irrigation in pediatric rhinosinusitis: A systematic review.

Gallant JN, Basem JI, Turner JH, Shannon CN, Virgin FW.

Int J Pediatr Otorhinolaryngol. 2018 May;108:155-162. doi: 10.1016/j.ijporl.2018.03.001. Epub 2018 Mar 6. Review.


Mycobacterial nucleoid associated proteins: An added dimension in gene regulation.

Kriel NL, Gallant J, van Wyk N, van Helden P, Sampson SL, Warren RM, Williams MJ.

Tuberculosis (Edinb). 2018 Jan;108:169-177. doi: 10.1016/ Epub 2017 Dec 13. Review.


Established, emerging and elusive molecular targets in the treatment of lung cancer.

Gallant JN, Lovly CM.

J Pathol. 2018 Apr;244(5):565-577. doi: 10.1002/path.5038. Epub 2018 Feb 14. Review.


Safety and Effectiveness of Ledipasvir and Sofosbuvir, With or Without Ribavirin, in Treatment-Experienced Patients With Genotype 1 Hepatitis C Virus Infection and Cirrhosis.

Lim JK, Liapakis AM, Shiffman ML, Lok AS, Zeuzem S, Terrault NA, Park JS, Landis CS, Hassan M, Gallant J, Kuo A, Pockros PJ, Vainorius M, Akushevich L, Michael L, Fried MW, Nelson DR, Ben-Ari Z; HCV-TARGET Study Group.

Clin Gastroenterol Hepatol. 2018 Nov;16(11):1811-1819.e4. doi: 10.1016/j.cgh.2017.12.037. Epub 2018 Jan 3.


HIV Drug Resistance in Adults Receiving Early vs. Delayed Antiretroviral Therapy: HPTN 052.

Palumbo PJ, Fogel JM, Hudelson SE, Wilson EA, Hart S, Hovind L, Piwowar-Manning E, Wallis C, Papathanasopoulos MA, Morgado MG, Saravanan S, Tripathy S, Eron JJ, Gallant JE, McCauley M, Gamble T, Hosseinipour MC, Kumarasamy N, Hakim JG, Pilotto JH, Kumwenda J, Akelo V, Godbole SV, Santos BR, Grinsztejn B, Panchia R, Chariyalertsak S, Makhema J, Badal-Faesen S, Chen YQ, Cohen MS, Eshleman SH.

J Acquir Immune Defic Syndr. 2018 Apr 15;77(5):484-491. doi: 10.1097/QAI.0000000000001623.


Rlim-Dependent and -Independent Pathways for X Chromosome Inactivation in Female ESCs.

Wang F, McCannell KN, Bošković A, Zhu X, Shin J, Yu J, Gallant J, Byron M, Lawrence JB, Zhu LJ, Jones SN, Rando OJ, Fazzio TG, Bach I.

Cell Rep. 2017 Dec 26;21(13):3691-3699. doi: 10.1016/j.celrep.2017.12.004.


Comorbidities Among US Patients With Prevalent HIV Infection-A Trend Analysis.

Gallant J, Hsue PY, Shreay S, Meyer N.

J Infect Dis. 2017 Dec 19;216(12):1525-1533. doi: 10.1093/infdis/jix518.


The Genome and Adult Somatic Transcriptome of the Mormyrid Electric Fish Paramormyrops kingsleyae.

Gallant JR, Losilla M, Tomlinson C, Warren WC.

Genome Biol Evol. 2017 Dec 1;9(12):3525-3530. doi: 10.1093/gbe/evx265.


Glecaprevir/Pibrentasvir in patients with hepatitis C virus genotype 1 or 4 and past direct-acting antiviral treatment failure.

Poordad F, Pol S, Asatryan A, Buti M, Shaw D, Hézode C, Felizarta F, Reindollar RW, Gordon SC, Pianko S, Fried MW, Bernstein DE, Gallant J, Lin CW, Lei Y, Ng TI, Krishnan P, Kopecky-Bromberg S, Kort J, Mensa FJ.

Hepatology. 2018 Apr;67(4):1253-1260. doi: 10.1002/hep.29671. Epub 2018 Jan 30.


Four ethical priorities for neurotechnologies and AI.

Yuste R, Goering S, Arcas BAY, Bi G, Carmena JM, Carter A, Fins JJ, Friesen P, Gallant J, Huggins JE, Illes J, Kellmeyer P, Klein E, Marblestone A, Mitchell C, Parens E, Pham M, Rubel A, Sadato N, Sullivan LS, Teicher M, Wasserman D, Wexler A, Whittaker M, Wolpaw J.

Nature. 2017 Nov 8;551(7679):159-163. doi: 10.1038/551159a. No abstract available.


Human Immunodeficiency Virus Medicine.

Gallant JE.

J Infect Dis. 2017 Sep 15;216(suppl_5):S624-S625. doi: 10.1093/infdis/jix238. No abstract available.


Healthcare utilization and direct costs of non-infectious comorbidities in HIV-infected patients in the USA.

Gallant J, Hsue P, Budd D, Meyer N.

Curr Med Res Opin. 2018 Jan;34(1):13-23. doi: 10.1080/03007995.2017.1383889. Epub 2017 Oct 6.


Bictegravir, emtricitabine, and tenofovir alafenamide versus dolutegravir, abacavir, and lamivudine for initial treatment of HIV-1 infection (GS-US-380-1489): a double-blind, multicentre, phase 3, randomised controlled non-inferiority trial.

Gallant J, Lazzarin A, Mills A, Orkin C, Podzamczer D, Tebas P, Girard PM, Brar I, Daar ES, Wohl D, Rockstroh J, Wei X, Custodio J, White K, Martin H, Cheng A, Quirk E.

Lancet. 2017 Nov 4;390(10107):2063-2072. doi: 10.1016/S0140-6736(17)32299-7. Epub 2017 Aug 31.


Evidence for intermolecular domain exchange in the Fab domains of dimer and oligomers of an IgG1 monoclonal antibody.

Luo Y, Raso SW, Gallant J, Steinmeyer C, Mabuchi Y, Lu Z, Entrican C, Rouse JC.

MAbs. 2017 Aug/Sep;9(6):916-926. doi: 10.1080/19420862.2017.1331803. Epub 2017 Jun 7.


The Hierarchical Cortical Organization of Human Speech Processing.

de Heer WA, Huth AG, Griffiths TL, Gallant JL, Theunissen FE.

J Neurosci. 2017 Jul 5;37(27):6539-6557. doi: 10.1523/JNEUROSCI.3267-16.2017. Epub 2017 Jun 6.


Safety and tolerability of long-acting cabotegravir injections in HIV-uninfected men (ECLAIR): a multicentre, double-blind, randomised, placebo-controlled, phase 2a trial.

Markowitz M, Frank I, Grant RM, Mayer KH, Elion R, Goldstein D, Fisher C, Sobieszczyk ME, Gallant JE, Van Tieu H, Weinberg W, Margolis DA, Hudson KJ, Stancil BS, Ford SL, Patel P, Gould E, Rinehart AR, Smith KY, Spreen WR.

Lancet HIV. 2017 Aug;4(8):e331-e340. doi: 10.1016/S2352-3018(17)30068-1. Epub 2017 May 22.


Virologic outcomes in early antiretroviral treatment: HPTN 052.

Eshleman SH, Wilson EA, Zhang XC, Ou SS, Piwowar-Manning E, Eron JJ, McCauley M, Gamble T, Gallant JE, Hosseinipour MC, Kumarasamy N, Hakim JG, Kalonga B, Pilotto JH, Grinsztejn B, Godbole SV, Chotirosniramit N, Santos BR, Shava E, Mills LA, Panchia R, Mwelase N, Mayer KH, Chen YQ, Cohen MS, Fogel JM.

HIV Clin Trials. 2017 May;18(3):100-109. doi: 10.1080/15284336.2017.1311056. Epub 2017 Apr 7.


Analysis of HIV Integrase Resistance in Black Men Who Have Sex with Men in the United States.

Chen I, Zhang Y, Cummings V, Cloherty GA, Connor M, Beauchamp G, Griffith S, Rose S, Gallant J, Scott HM, Shoptaw S, Del Rio C, Kuo I, Mannheimer S, Tieu HV, Hurt CB, Fields SD, Wheeler DP, Mayer KH, Koblin BA, Eshleman SH.

AIDS Res Hum Retroviruses. 2017 Jul;33(7):745-748. doi: 10.1089/aid.2017.0005. Epub 2017 Apr 6.


Virological Surveillance of Influenza A Subtypes Isolated in 2014 from Clinical Outbreaks in Canadian Swine.

Grgić H, Gallant J, Poljak Z.

Viruses. 2017 Mar 21;9(3). pii: E55. doi: 10.3390/v9030055.


Brief Report: Long-Term (96-Week) Efficacy and Safety After Switching From Tenofovir Disoproxil Fumarate to Tenofovir Alafenamide in HIV-Infected, Virologically Suppressed Adults.

Raffi F, Orkin C, Clarke A, Slama L, Gallant J, Daar E, Henry K, Santana-Bagur J, Stein DK, Bellos N, Scarsella A, Yan M, Abram ME, Cheng A, Rhee MS.

J Acquir Immune Defic Syndr. 2017 Jun 1;75(2):226-231. doi: 10.1097/QAI.0000000000001344.


A Conversation Among the IAS-USA Board of Directors: Hot Topics and Emerging Data in HIV Research and Care.

Benson CA, Currier JS, Del Rio C, Gallant JE, Gulick RM, Marrazzo JM, Richman DD, Saag MS, Schooley RT, Volberding PA.

Top Antivir Med. 2017 Dec/Jan;24(4):142-151.


Antiviral Activity, Safety, and Pharmacokinetics of Bictegravir as 10-Day Monotherapy in HIV-1-Infected Adults.

Gallant JE, Thompson M, DeJesus E, Voskuhl GW, Wei X, Zhang H, White K, Cheng A, Quirk E, Martin H.

J Acquir Immune Defic Syndr. 2017 May 1;75(1):61-66. doi: 10.1097/QAI.0000000000001306.


Eye movement-invariant representations in the human visual system.

Nishimoto S, Huth AG, Bilenko NY, Gallant JL.

J Vis. 2017 Jan 1;17(1):11. doi: 10.1167/17.1.11.


Dolutegravir monotherapy: when should clinical practice be clinical research?

Gallant J, Sugarman J.

Antivir Ther. 2017;22(2):93-95. doi: 10.3851/IMP3113. Epub 2016 Dec 15. No abstract available.


Pyrcca: Regularized Kernel Canonical Correlation Analysis in Python and Its Applications to Neuroimaging.

Bilenko NY, Gallant JL.

Front Neuroinform. 2016 Nov 22;10:49. eCollection 2016.


Decoding the Semantic Content of Natural Movies from Human Brain Activity.

Huth AG, Lee T, Nishimoto S, Bilenko NY, Vu AT, Gallant JL.

Front Syst Neurosci. 2016 Oct 7;10:81. eCollection 2016.


Atazanavir Plus Cobicistat: Week 48 and Week 144 Subgroup Analyses of a Phase 3, Randomized, Double-Blind, Active-Controlled Trial.

Gallant J, Moyle G, Berenguer J, Shalit P, Cao H, Liu YP, Myers J, Rosenblatt L, Yang L, Szwarcberg J.

Curr HIV Res. 2017;15(3):216-224. doi: 10.2174/1570162X14666161021102728.


Electric fish genomics: Progress, prospects, and new tools for neuroethology.

Pitchers WR, Constantinou SJ, Losilla M, Gallant JR.

J Physiol Paris. 2016 Oct;110(3 Pt B):259-272. doi: 10.1016/j.jphysparis.2016.10.003. Epub 2016 Oct 18. Review.


A Randomized, Open-Label Trial to Evaluate Switching to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Plus Darunavir in Treatment-Experienced HIV-1-Infected Adults.

Huhn GD, Tebas P, Gallant J, Wilkin T, Cheng A, Yan M, Zhong L, Callebaut C, Custodio JM, Fordyce MW, Das M, McCallister S.

J Acquir Immune Defic Syndr. 2017 Feb 1;74(2):193-200. doi: 10.1097/QAI.0000000000001193.


The Zn-finger domain of MdmX suppresses cancer progression by promoting genome stability in p53-mutant cells.

Matijasevic Z, Krzywicka-Racka A, Sluder G, Gallant J, Jones SN.

Oncogenesis. 2016 Oct 3;5(10):e262. doi: 10.1038/oncsis.2016.62.



Gallant J.

Posit Aware. 2015 Nov-Dec;27(7):38-9. No abstract available.


Antiretroviral Therapy for the Prevention of HIV-1 Transmission.

Cohen MS, Chen YQ, McCauley M, Gamble T, Hosseinipour MC, Kumarasamy N, Hakim JG, Kumwenda J, Grinsztejn B, Pilotto JH, Godbole SV, Chariyalertsak S, Santos BR, Mayer KH, Hoffman IF, Eshleman SH, Piwowar-Manning E, Cottle L, Zhang XC, Makhema J, Mills LA, Panchia R, Faesen S, Eron J, Gallant J, Havlir D, Swindells S, Elharrar V, Burns D, Taha TE, Nielsen-Saines K, Celentano DD, Essex M, Hudelson SE, Redd AD, Fleming TR; HPTN 052 Study Team.

N Engl J Med. 2016 Sep 1;375(9):830-9. doi: 10.1056/NEJMoa1600693. Epub 2016 Jul 18.


Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults: 2016 Recommendations of the International Antiviral Society-USA Panel.

Günthard HF, Saag MS, Benson CA, del Rio C, Eron JJ, Gallant JE, Hoy JF, Mugavero MJ, Sax PE, Thompson MA, Gandhi RT, Landovitz RJ, Smith DM, Jacobsen DM, Volberding PA.

JAMA. 2016 Jul 12;316(2):191-210. doi: 10.1001/jama.2016.8900.


Sorafenib and Quinacrine Target Anti-Apoptotic Protein MCL1: A Poor Prognostic Marker in Anaplastic Thyroid Cancer (ATC).

Abdulghani J, Gokare P, Gallant JN, Dicker D, Whitcomb T, Cooper T, Liao J, Derr J, Liu J, Goldenberg D, Finnberg NK, El-Deiry WS.

Clin Cancer Res. 2016 Dec 15;22(24):6192-6203. Epub 2016 Jun 15.


Brief Report: Efficacy and Safety of Switching to a Single-Tablet Regimen of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide in HIV-1/Hepatitis B-Coinfected Adults.

Gallant J, Brunetta J, Crofoot G, Benson P, Mills A, Brinson C, Oka S, Cheng A, Garner W, Fordyce M, Das M, McCallister S; GS-US-292-1249 Study Investigators.

J Acquir Immune Defic Syndr. 2016 Nov 1;73(3):294-298.


Natural speech reveals the semantic maps that tile human cerebral cortex.

Huth AG, de Heer WA, Griffiths TL, Theunissen FE, Gallant JL.

Nature. 2016 Apr 28;532(7600):453-8. doi: 10.1038/nature17637.


EGFR Fusions as Novel Therapeutic Targets in Lung Cancer.

Konduri K, Gallant JN, Chae YK, Giles FJ, Gitlitz BJ, Gowen K, Ichihara E, Owonikoko TK, Peddareddigari V, Ramalingam SS, Reddy SK, Eaby-Sandy B, Vavalà T, Whiteley A, Chen H, Yan Y, Sheehan JH, Meiler J, Morosini D, Ross JS, Stephens PJ, Miller VA, Ali SM, Lovly CM.

Cancer Discov. 2016 Jun;6(6):601-11. doi: 10.1158/2159-8290.CD-16-0075. Epub 2016 Apr 21.


Efficacy and safety of tenofovir alafenamide versus tenofovir disoproxil fumarate given as fixed-dose combinations containing emtricitabine as backbones for treatment of HIV-1 infection in virologically suppressed adults: a randomised, double-blind, active-controlled phase 3 trial.

Gallant JE, Daar ES, Raffi F, Brinson C, Ruane P, DeJesus E, Johnson M, Clumeck N, Osiyemi O, Ward D, Morales-Ramirez J, Yan M, Abram ME, Plummer A, Cheng AK, Rhee MS.

Lancet HIV. 2016 Apr;3(4):e158-65. doi: 10.1016/S2352-3018(16)00024-2. Epub 2016 Mar 14.


Predictors of Difficult Intubation with the Bonfils Rigid Fiberscope.

Nowakowski M, Williams S, Gallant J, Ruel M, Robitaille A.

Anesth Analg. 2016 Jun;122(6):1901-6. doi: 10.1213/ANE.0000000000001258.


Brief Report: HIV Drug Resistance in Adults Failing Early Antiretroviral Treatment: Results From the HIV Prevention Trials Network 052 Trial.

Fogel JM, Hudelson SE, Ou SS, Hart S, Wallis C, Morgado MG, Saravanan S, Tripathy S, Hovind L, Piwowar-Manning E, Sabin D, McCauley M, Gamble T, Zhang XC, Eron JJ, Gallant JE, Kumwenda J, Makhema J, Kumarasamy N, Chariyalertsak S, Hakim J, Badal-Faesen S, Akelo V, Hosseinipour MC, Santos BR, Godbole SV, Pilotto JH, Grinsztejn B, Panchia R, Mayer KH, Chen YQ, Cohen MS, Eshleman SH.

J Acquir Immune Defic Syndr. 2016 Jul 1;72(3):304-9. doi: 10.1097/QAI.0000000000000951.


Glutamate Dehydrogenase Is Required by Mycobacterium bovis BCG for Resistance to Cellular Stress.

Gallant JL, Viljoen AJ, van Helden PD, Wiid IJ.

PLoS One. 2016 Jan 29;11(1):e0147706. doi: 10.1371/journal.pone.0147706. eCollection 2016.

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