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Epigenetic Regulation of TLR4 in Diabetic Macrophages Modulates Immunometabolism and Wound Repair.

Davis FM, denDekker A, Kimball A, Joshi AD, El Azzouny M, Wolf SJ, Obi AT, Lipinski J, Gudjonsson JE, Xing X, Plazyo O, Audu C, Melvin WJ, Singer K, Henke PK, Moore BB, Burant C, Kunkel SL, Gallagher KA.

J Immunol. 2020 Mar 23. pii: ji1901263. doi: 10.4049/jimmunol.1901263. [Epub ahead of print]


TNF-α regulates diabetic macrophage function through the histone acetyltransferase MOF.

denDekker AD, Davis FM, Joshi AD, Wolf SJ, Allen R, Lipinski J, Nguyen B, Kirma J, Nycz D, Bermick J, Moore BB, Gudjonsson JE, Kunkel SL, Gallagher KA.

JCI Insight. 2020 Mar 12;5(5). pii: 132306. doi: 10.1172/jci.insight.132306.


Diabetic Foot Infections [Internet].

Mills JP, Patel P, Broekhuizen E, Burdick S, DeGeorge C, Gallagher KA, Haase SC, Holmes CM, Jacobson JA, Nagel JL, Seagull FJ, Silver AE, Somand DM, Talusan PG, Wensman J, Wrobel JS.

Ann Arbor (MI): Michigan Medicine University of Michigan; 2019 Oct.


Ly6CLo Monocyte/Macrophages are Essential for Thrombus Resolution in a Murine Model of Venous Thrombosis.

Kimball AS, Obi AT, Luke CE, Dowling AR, Cai Q, Adili R, Jankowski H, Schaller M, Holinstadt M, Jaffer FA, Kunkel SL, Gallagher KA, Henke PK.

Thromb Haemost. 2020 Feb;120(2):289-299. doi: 10.1055/s-0039-3400959. Epub 2019 Dec 30.


Accessing the academic influence of vascular surgeons within the National Institutes of Health iCite database.

Davis FM, Obi AT, Gallagher KA, Henke PK.

J Vasc Surg. 2019 Dec 9. pii: S0741-5214(19)32497-8. doi: 10.1016/j.jvs.2019.09.036. [Epub ahead of print]


c-di-GMP Arms an Anti-σ to Control Progression of Multicellular Differentiation in Streptomyces.

Gallagher KA, Schumacher MA, Bush MJ, Bibb MJ, Chandra G, Holmes NA, Zeng W, Henderson M, Zhang H, Findlay KC, Brennan RG, Buttner MJ.

Mol Cell. 2020 Feb 6;77(3):586-599.e6. doi: 10.1016/j.molcel.2019.11.006. Epub 2019 Dec 3.


Sepsis Induces Prolonged Epigenetic Modifications in Bone Marrow and Peripheral Macrophages Impairing Inflammation and Wound Healing.

Davis FM, Schaller MA, Dendekker A, Joshi AD, Kimball AS, Evanoff H, Wilke C, Obi AT, Melvin WJ, Cavassani K, Scola M, Carson B, Moser S, Blanc V, Engoren M, Moore BB, Kunkel SL, Gallagher KA.

Arterioscler Thromb Vasc Biol. 2019 Nov;39(11):2353-2366. doi: 10.1161/ATVBAHA.119.312754. Epub 2019 Sep 5.


The Histone Methyltransferase Setdb2 Modulates Macrophage Phenotype and Uric Acid Production in Diabetic Wound Repair.

Kimball AS, Davis FM, denDekker A, Joshi AD, Schaller MA, Bermick J, Xing X, Burant CF, Obi AT, Nysz D, Robinson S, Allen R, Lukacs NW, Henke PK, Gudjonsson JE, Moore BB, Kunkel SL, Gallagher KA.

Immunity. 2019 Aug 20;51(2):258-271.e5. doi: 10.1016/j.immuni.2019.06.015. Epub 2019 Jul 23.


Invited commentary.

Davis FM, Gallagher KA.

J Vasc Surg. 2019 Aug;70(2):598-599. doi: 10.1016/j.jvs.2018.10.010. No abstract available.


SIRT3 Regulates Macrophage-Mediated Inflammation in Diabetic Wound Repair.

Boniakowski AM, denDekker AD, Davis FM, Joshi A, Kimball AS, Schaller M, Allen R, Bermick J, Nycz D, Skinner ME, Robinson S, Obi AT, Moore BB, Gudjonsson JE, Lombard D, Kunkel SL, Gallagher KA.

J Invest Dermatol. 2019 Dec;139(12):2528-2537.e2. doi: 10.1016/j.jid.2019.05.017. Epub 2019 Jun 15.


Evaluating gender bias in an eating disorder risk assessment questionnaire for athletes.

Gallagher KA, Sonneville KR, Hazzard VM, Carson TL, Needham BL.

Eat Disord. 2019 May 11:1-13. doi: 10.1080/10640266.2019.1613846. [Epub ahead of print]


Medical and Psychological Considerations for Carbohydrate-Restricted Diets in Youth With Type 1 Diabetes.

Gallagher KAS, DeSalvo D, Gregory J, Hilliard ME.

Curr Diab Rep. 2019 Apr 27;19(6):27. doi: 10.1007/s11892-019-1153-2. Review.


Validation of the UCLA PTSD Reaction Index for DSM-5: A Developmentally Informed Assessment Tool for Youth.

Kaplow JB, Rolon-Arroyo B, Layne CM, Rooney E, Oosterhoff B, Hill R, Steinberg AM, Lotterman J, Gallagher KAS, Pynoos RS.

J Am Acad Child Adolesc Psychiatry. 2020 Jan;59(1):186-194. doi: 10.1016/j.jaac.2018.10.019. Epub 2019 Apr 3.


The effects of testosterone replacement therapy on the prostate: a clinical perspective.

Miah S, Tharakan T, Gallagher KA, Shah TT, Winkler M, Jayasena CN, Ahmed HU, Minhas S.

F1000Res. 2019 Feb 25;8. pii: F1000 Faculty Rev-217. doi: 10.12688/f1000research.16497.1. eCollection 2019. Review.


Epigenetic Mechanisms in Monocytes/Macrophages Regulate Inflammation in Cardiometabolic and Vascular Disease.

Davis FM, Gallagher KA.

Arterioscler Thromb Vasc Biol. 2019 Apr;39(4):623-634. doi: 10.1161/ATVBAHA.118.312135. Review.


Histone Methylation Directs Myeloid TLR4 Expression and Regulates Wound Healing following Cutaneous Tissue Injury.

Davis FM, Kimball A, denDekker A, Joshi AD, Boniakowski AE, Nysz D, Allen RM, Obi A, Singer K, Henke PK, Moore BB, Kunkel SL, Gallagher KA.

J Immunol. 2019 Mar 15;202(6):1777-1785. doi: 10.4049/jimmunol.1801258. Epub 2019 Feb 1.


Targeting epigenetic mechanisms in diabetic wound healing.

den Dekker A, Davis FM, Kunkel SL, Gallagher KA.

Transl Res. 2019 Feb;204:39-50. doi: 10.1016/j.trsl.2018.10.001. Epub 2018 Oct 10. Review.


Aggressive Phenotype of Intravascular Lymphoma Relative to Other Malignant Intraabdominal Tumors Requiring Vascular Reconstruction.

Obi AT, Kim GY, Coleman DM, Osborne NH, Rectenwald JE, Gallagher KA, Henke PK, Eliason JL.

Ann Vasc Surg. 2019 Jan;54:72-83. doi: 10.1016/j.avsg.2018.09.003. Epub 2018 Sep 27.


Murine macrophage chemokine receptor CCR2 plays a crucial role in macrophage recruitment and regulated inflammation in wound healing.

Boniakowski AE, Kimball AS, Joshi A, Schaller M, Davis FM, denDekker A, Obi AT, Moore BB, Kunkel SL, Gallagher KA.

Eur J Immunol. 2018 Sep;48(9):1445-1455. doi: 10.1002/eji.201747400. Epub 2018 Jun 26.


Invited commentary.

Gallagher KA.

J Vasc Surg. 2018 Jun;67(6):1920. doi: 10.1016/j.jvs.2017.05.083. No abstract available.


Early Outcomes following Endovascular, Open Surgical, and Hybrid Revascularization for Lower Extremity Acute Limb Ischemia.

Davis FM, Albright J, Gallagher KA, Gurm HS, Koenig GC, Schreiber T, Grossman PM, Henke PK.

Ann Vasc Surg. 2018 Aug;51:106-112. doi: 10.1016/j.avsg.2017.12.025. Epub 2018 Mar 5.


Ly6CHi Blood Monocyte/Macrophage Drive Chronic Inflammation and Impair Wound Healing in Diabetes Mellitus.

Kimball A, Schaller M, Joshi A, Davis FM, denDekker A, Boniakowski A, Bermick J, Obi A, Moore B, Henke PK, Kunkel SL, Gallagher KA.

Arterioscler Thromb Vasc Biol. 2018 May;38(5):1102-1114. doi: 10.1161/ATVBAHA.118.310703. Epub 2018 Mar 1.


The Spectrum Analysis Solution (SAS) System: Theoretical Analysis, Hardware Design and Implementation.

Narayanan RM, Pooler RK, Martone AF, Gallagher KA, Sherbondy KD.

Sensors (Basel). 2018 Feb 22;18(2). pii: E652. doi: 10.3390/s18020652.


Intravascular ultrasound as a novel tool for the diagnosis and targeted treatment of functional popliteal artery entrapment syndrome.

Boniakowski AE, Davis F, Campbell D, Khaja M, Gallagher KA.

J Vasc Surg Cases Innov Tech. 2017 Apr 25;3(2):74-78. doi: 10.1016/j.jvscit.2017.02.006. eCollection 2017 Jun.


Targeted Interventions to Advance a Culture of Inquiry at a Large, Multicampus Hospital Among Nurses.

Carter EJ, Rivera RR, Gallagher KA, Cato KD.

J Nurs Adm. 2018 Jan;48(1):18-24. doi: 10.1097/NNA.0000000000000565.


The STAT4/MLL1 Epigenetic Axis Regulates the Antimicrobial Functions of Murine Macrophages.

Carson WF 4th, Cavassani KA, Soares EM, Hirai S, Kittan NA, Schaller MA, Scola MM, Joshi A, Matsukawa A, Aronoff DM, Johnson CN, Dou Y, Gallagher KA, Kunkel SL.

J Immunol. 2017 Sep 1;199(5):1865-1874. doi: 10.4049/jimmunol.1601272. Epub 2017 Jul 21.


Psychiatric Boarding in the Pediatric Inpatient Medical Setting: A Retrospective Analysis.

Gallagher KAS, Bujoreanu IS, Cheung P, Choi C, Golden S, Brodziak K, Andrade G, Ibeziako P.

Hosp Pediatr. 2017 Aug;7(8):444-450. doi: 10.1542/hpeds.2017-0005. Epub 2017 Jul 17.


The Histone Methyltransferase MLL1 Directs Macrophage-Mediated Inflammation in Wound Healing and Is Altered in a Murine Model of Obesity and Type 2 Diabetes.

Kimball AS, Joshi A, Carson WF 4th, Boniakowski AE, Schaller M, Allen R, Bermick J, Davis FM, Henke PK, Burant CF, Kunkel SL, Gallagher KA.

Diabetes. 2017 Sep;66(9):2459-2471. doi: 10.2337/db17-0194. Epub 2017 Jun 29.


Macrophage-Mediated Inflammation in Normal and Diabetic Wound Healing.

Boniakowski AE, Kimball AS, Jacobs BN, Kunkel SL, Gallagher KA.

J Immunol. 2017 Jul 1;199(1):17-24. doi: 10.4049/jimmunol.1700223. Review.


Notch Regulates Macrophage-Mediated Inflammation in Diabetic Wound Healing.

Kimball AS, Joshi AD, Boniakowski AE, Schaller M, Chung J, Allen R, Bermick J, Carson WF 4th, Henke PK, Maillard I, Kunkel SL, Gallagher KA.

Front Immunol. 2017 Jun 1;8:635. doi: 10.3389/fimmu.2017.00635. eCollection 2017.


Natural History of Iatrogenic Pediatric Femoral Artery Injury.

Andraska EA, Jackson T, Chen H, Gallagher KA, Eliason JL, Coleman DM.

Ann Vasc Surg. 2017 Jul;42:205-213. doi: 10.1016/j.avsg.2016.11.016. Epub 2017 Mar 22.


Enhancement of macrophage inflammatory responses by CCL2 is correlated with increased miR-9 expression and downregulation of the ERK1/2 phosphatase Dusp6.

Carson WF 4th, Salter-Green SE, Scola MM, Joshi A, Gallagher KA, Kunkel SL.

Cell Immunol. 2017 Apr;314:63-72. doi: 10.1016/j.cellimm.2017.02.005. Epub 2017 Feb 22.


Ecological implications of hypoxia-triggered shifts in secondary metabolism.

Gallagher KA, Wanger G, Henderson J, Llorente M, Hughes CC, Jensen PR.

Environ Microbiol. 2017 Jun;19(6):2182-2191. doi: 10.1111/1462-2920.13700. Epub 2017 Mar 21.


Dimethyl Itaconate Is Not Metabolized into Itaconate Intracellularly.

ElAzzouny M, Tom CT, Evans CR, Olson LL, Tanga MJ, Gallagher KA, Martin BR, Burant CF.

J Biol Chem. 2017 Mar 24;292(12):4766-4769. doi: 10.1074/jbc.C117.775270. Epub 2017 Feb 10.


Alterations in macrophage phenotypes in experimental venous thrombosis.

Gallagher KA, Obi AT, Elfline MA, Hogikyan E, Luke CE, Henke S, Coleman D, Henke PK.

J Vasc Surg Venous Lymphat Disord. 2016 Oct;4(4):463-71. doi: 10.1016/j.jvsv.2016.03.005.


The "3-Pack" Examination Is Critical for Comprehensive Evaluation of the Biceps-Labrum Complex and the Bicipital Tunnel: A Prospective Study.

Taylor SA, Newman AM, Dawson C, Gallagher KA, Bowers A, Nguyen J, Fabricant PD, O'Brien SJ.

Arthroscopy. 2017 Jan;33(1):28-38. doi: 10.1016/j.arthro.2016.05.015. Epub 2016 Jul 21.


Genomic insights into the evolution of hybrid isoprenoid biosynthetic gene clusters in the MAR4 marine streptomycete clade.

Gallagher KA, Jensen PR.

BMC Genomics. 2015 Nov 17;16:960. doi: 10.1186/s12864-015-2110-3.


Optimizing flushing parameters in intracoronary optical coherence tomography: an in vivo swine study.

Suter MJ, Kashiwagi M, Gallagher KA, Nadkarni SK, Asanani N, Tanaka A, Conditt GB, Tellez A, Milewski K, Kaluza GL, Granada JF, Bouma BE, Tearney GJ.

Int J Cardiovasc Imaging. 2015 Aug;31(6):1097-106. doi: 10.1007/s10554-015-0668-0. Epub 2015 Apr 29.


Predictors of compliance with surveillance after endovascular aneurysm repair and comparative survival outcomes.

Wu CY, Chen H, Gallagher KA, Eliason JL, Rectenwald JE, Coleman DM.

J Vasc Surg. 2015 Jul;62(1):27-35. doi: 10.1016/j.jvs.2015.02.023. Epub 2015 Apr 8.


Ready, set, relax: biofeedback-assisted relaxation training (BART) in a pediatric psychiatry consultation service.

McKenna K, Gallagher KA, Forbes PW, Ibeziako P.

Psychosomatics. 2015 Jul-Aug;56(4):381-9. doi: 10.1016/j.psym.2014.06.003. Epub 2014 Jun 20.


Delaying in vivo exposure to a tarantula with very brief exposure to phobic stimuli.

Siegel P, Gallagher KA.

J Behav Ther Exp Psychiatry. 2015 Mar;46:182-8.


Epigenetic changes in bone marrow progenitor cells influence the inflammatory phenotype and alter wound healing in type 2 diabetes.

Gallagher KA, Joshi A, Carson WF, Schaller M, Allen R, Mukerjee S, Kittan N, Feldman EL, Henke PK, Hogaboam C, Burant CF, Kunkel SL.

Diabetes. 2015 Apr;64(4):1420-30. doi: 10.2337/db14-0872. Epub 2014 Nov 3.


Contemporary outcomes with percutaneous vascular interventions for peripheral critical limb ischemia in those with and without poly-vascular disease.

Krishnamurthy V, Munir K, Rectenwald JE, Mansour A, Hans S, Eliason JL, Escobar GA, Gallagher KA, Grossman PM, Gurm HS, Share DA, Henke PK.

Vasc Med. 2014 Dec;19(6):491-9. doi: 10.1177/1358863X14552013. Epub 2014 Oct 7.


Bone marrow adipose tissue is an endocrine organ that contributes to increased circulating adiponectin during caloric restriction.

Cawthorn WP, Scheller EL, Learman BS, Parlee SD, Simon BR, Mori H, Ning X, Bree AJ, Schell B, Broome DT, Soliman SS, DelProposto JL, Lumeng CN, Mitra A, Pandit SV, Gallagher KA, Miller JD, Krishnan V, Hui SK, Bredella MA, Fazeli PK, Klibanski A, Horowitz MC, Rosen CJ, MacDougald OA.

Cell Metab. 2014 Aug 5;20(2):368-375. doi: 10.1016/j.cmet.2014.06.003. Epub 2014 Jul 3.


Feasibility and impact of multidisciplinary training of an evidence-based intervention within a pediatric psychiatry consultation service.

Gallagher KA, McKenna K, Ibeziako P.

Acad Psychiatry. 2014 Aug;38(4):445-50. doi: 10.1007/s40596-014-0121-z. Epub 2014 May 15.


Impact of sex on morbidity and mortality rates after lower extremity interventions for peripheral arterial disease: observations from the Blue Cross Blue Shield of Michigan Cardiovascular Consortium.

Jackson EA, Munir K, Schreiber T, Rubin JR, Cuff R, Gallagher KA, Henke PK, Gurm HS, Grossman PM.

J Am Coll Cardiol. 2014 Jun 17;63(23):2525-2530. doi: 10.1016/j.jacc.2014.03.036. Epub 2014 Apr 23.


Esophageal-guided biopsy with volumetric laser endomicroscopy and laser cautery marking: a pilot clinical study.

Suter MJ, Gora MJ, Lauwers GY, Arnason T, Sauk J, Gallagher KA, Kava L, Tan KM, Soomro AR, Gallagher TP, Gardecki JA, Bouma BE, Rosenberg M, Nishioka NS, Tearney GJ.

Gastrointest Endosc. 2014 Jun;79(6):886-96. doi: 10.1016/j.gie.2013.11.016. Epub 2014 Jan 23.


Cytokine induced phenotypic and epigenetic signatures are key to establishing specific macrophage phenotypes.

Kittan NA, Allen RM, Dhaliwal A, Cavassani KA, Schaller M, Gallagher KA, Carson WF 4th, Mukherjee S, Grembecka J, Cierpicki T, Jarai G, Westwick J, Kunkel SL, Hogaboam CM.

PLoS One. 2013 Oct 21;8(10):e78045. doi: 10.1371/journal.pone.0078045. eCollection 2013.


Phylogenetic and chemical diversity of a hybrid-isoprenoid-producing streptomycete lineage.

Gallagher KA, Rauscher K, Pavan Ioca L, Jensen PR.

Appl Environ Microbiol. 2013 Nov;79(22):6894-902. doi: 10.1128/AEM.01814-13. Epub 2013 Aug 30.


Outcomes after late explantation of aortic endografts depend on indication for explantation.

Arya S, Coleman DM, Knepper J, Henke PK, Upchurch GR, Rectenwald JE, Criado E, Eliason JL, Gallagher KA.

Ann Vasc Surg. 2013 Oct;27(7):865-73. doi: 10.1016/j.avsg.2013.03.009.


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