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Items: 27


A statistical and biological response to an informatics appraisal of healthy aging gene signatures.

Timmons JA, Gallagher IJ, Sood S, Phillips B, Crossland H, Howard R, Kraus WE, Atherton PJ.

Genome Biol. 2019 Aug 2;20(1):152. doi: 10.1186/s13059-019-1734-z.


The acute transcriptional response to resistance exercise: impact of age and contraction mode.

Deane CS, Ames RM, Phillips BE, Weedon MN, Willis CRG, Boereboom C, Abdulla H, Bukhari SSI, Lund JN, Williams JP, Wilkinson DJ, Smith K, Gallagher IJ, Kadi F, Szewczyk NJ, Atherton PJ, Etheridge T.

Aging (Albany NY). 2019 Apr 15;11(7):2111-2126. doi: 10.18632/aging.101904.


A coding and non-coding transcriptomic perspective on the genomics of human metabolic disease.

Timmons JA, Atherton PJ, Larsson O, Sood S, Blokhin IO, Brogan RJ, Volmar CH, Josse AR, Slentz C, Wahlestedt C, Phillips SM, Phillips BE, Gallagher IJ, Kraus WE.

Nucleic Acids Res. 2018 Sep 6;46(15):7772-7792. doi: 10.1093/nar/gky570.


Assessing the Role of Muscle Protein Breakdown in Response to Nutrition and Exercise in Humans.

Tipton KD, Hamilton DL, Gallagher IJ.

Sports Med. 2018 Mar;48(Suppl 1):53-64. doi: 10.1007/s40279-017-0845-5. Review.


Variation in the Early Host-Pathogen Interaction of Bovine Macrophages with Divergent Mycobacterium bovis Strains in the United Kingdom.

Jensen K, Gallagher IJ, Johnston N, Welsh M, Skuce R, Williams JL, Glass EJ.

Infect Immun. 2018 Feb 20;86(3). pii: e00385-17. doi: 10.1128/IAI.00385-17. Print 2018 Mar.


Multiple AMPK activators inhibit l-carnitine uptake in C2C12 skeletal muscle myotubes.

Shaw A, Jeromson S, Watterson KR, Pediani JD, Gallagher IJ, Whalley T, Dreczkowski G, Brooks N, Galloway SD, Hamilton DL.

Am J Physiol Cell Physiol. 2017 Jun 1;312(6):C689-C696. doi: 10.1152/ajpcell.00026.2016. Epub 2017 Mar 15.


Molecular studies of exercise, skeletal muscle, and ageing.

Timmons JA, Gallagher IJ.

F1000Res. 2016 Jun 2;5. pii: F1000 Faculty Rev-1087. doi: 10.12688/f1000research.8255.1. eCollection 2016. Review.


iGEMS: an integrated model for identification of alternative exon usage events.

Sood S, Szkop KJ, Nakhuda A, Gallagher IJ, Murie C, Brogan RJ, Kaprio J, Kainulainen H, Atherton PJ, Kujala UM, Gustafsson T, Larsson O, Timmons JA.

Nucleic Acids Res. 2016 Jun 20;44(11):e109. doi: 10.1093/nar/gkw263. Epub 2016 Apr 19.


Live and inactivated Salmonella enterica serovar Typhimurium stimulate similar but distinct transcriptome profiles in bovine macrophages and dendritic cells.

Jensen K, Gallagher IJ, Kaliszewska A, Zhang C, Abejide O, Gallagher MP, Werling D, Glass EJ.

Vet Res. 2016 Mar 22;47:46. doi: 10.1186/s13567-016-0328-y.


Omics/systems biology and cancer cachexia.

Gallagher IJ, Jacobi C, Tardif N, Rooyackers O, Fearon K.

Semin Cell Dev Biol. 2016 Jun;54:92-103. doi: 10.1016/j.semcdb.2015.12.022. Epub 2016 Jan 16. Review.


Omega-3 Fatty Acids and Skeletal Muscle Health.

Jeromson S, Gallagher IJ, Galloway SD, Hamilton DL.

Mar Drugs. 2015 Nov 19;13(11):6977-7004. doi: 10.3390/md13116977. Review.


Multiple sources of bias confound functional enrichment analysis of global -omics data.

Timmons JA, Szkop KJ, Gallagher IJ.

Genome Biol. 2015 Sep 7;16:186. doi: 10.1186/s13059-015-0761-7.


A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status.

Sood S, Gallagher IJ, Lunnon K, Rullman E, Keohane A, Crossland H, Phillips BE, Cederholm T, Jensen T, van Loon LJ, Lannfelt L, Kraus WE, Atherton PJ, Howard R, Gustafsson T, Hodges A, Timmons JA.

Genome Biol. 2015 Sep 7;16:185. doi: 10.1186/s13059-015-0750-x.


Evaluating potential biomarkers of cachexia and survival in skeletal muscle of upper gastrointestinal cancer patients.

Stephens NA, Skipworth RJ, Gallagher IJ, Greig CA, Guttridge DC, Ross JA, Fearon KC.

J Cachexia Sarcopenia Muscle. 2015 Mar;6(1):53-61. doi: 10.1002/jcsm.12005. Epub 2015 Mar 31.


Molecular brakes regulating mTORC1 activation in skeletal muscle following synergist ablation.

Hamilton DL, Philp A, MacKenzie MG, Patton A, Towler MC, Gallagher IJ, Bodine SC, Baar K.

Am J Physiol Endocrinol Metab. 2014 Aug 15;307(4):E365-73. doi: 10.1152/ajpendo.00674.2013. Epub 2014 Jun 24.


Increased skeletal muscle 11βHSD1 mRNA is associated with lower muscle strength in ageing.

Kilgour AH, Gallagher IJ, MacLullich AM, Andrew R, Gray CD, Hyde P, Wackerhage H, Husi H, Ross JA, Starr JM, Chapman KE, Fearon KC, Walker BR, Greig CA.

PLoS One. 2013 Dec 31;8(12):e84057. doi: 10.1371/journal.pone.0084057. eCollection 2013.


Resistance to aerobic exercise training causes metabolic dysfunction and reveals novel exercise-regulated signaling networks.

Lessard SJ, Rivas DA, Alves-Wagner AB, Hirshman MF, Gallagher IJ, Constantin-Teodosiu D, Atkins R, Greenhaff PL, Qi NR, Gustafsson T, Fielding RA, Timmons JA, Britton SL, Koch LG, Goodyear LJ.

Diabetes. 2013 Aug;62(8):2717-27. doi: 10.2337/db13-0062. Epub 2013 Apr 22.


Induction of IL-4Rα-dependent microRNAs identifies PI3K/Akt signaling as essential for IL-4-driven murine macrophage proliferation in vivo.

Rückerl D, Jenkins SJ, Laqtom NN, Gallagher IJ, Sutherland TE, Duncan S, Buck AH, Allen JE.

Blood. 2012 Sep 13;120(11):2307-16. doi: 10.1182/blood-2012-02-408252. Epub 2012 Aug 1.


Suppression of skeletal muscle turnover in cancer cachexia: evidence from the transcriptome in sequential human muscle biopsies.

Gallagher IJ, Stephens NA, MacDonald AJ, Skipworth RJ, Husi H, Greig CA, Ross JA, Timmons JA, Fearon KC.

Clin Cancer Res. 2012 May 15;18(10):2817-27. doi: 10.1158/1078-0432.CCR-11-2133. Epub 2012 Mar 27.


Sexual dimorphism modulates the impact of cancer cachexia on lower limb muscle mass and function.

Stephens NA, Gray C, MacDonald AJ, Tan BH, Gallagher IJ, Skipworth RJ, Ross JA, Fearon KC, Greig CA.

Clin Nutr. 2012 Aug;31(4):499-505. doi: 10.1016/j.clnu.2011.12.008. Epub 2012 Jan 31.


Gene-chip studies of adipogenesis-regulated microRNAs in mouse primary adipocytes and human obesity.

Keller P, Gburcik V, Petrovic N, Gallagher IJ, Nedergaard J, Cannon B, Timmons JA.

BMC Endocr Disord. 2011 Mar 22;11:7. doi: 10.1186/1472-6823-11-7.


High responders to resistance exercise training demonstrate differential regulation of skeletal muscle microRNA expression.

Davidsen PK, Gallagher IJ, Hartman JW, Tarnopolsky MA, Dela F, Helge JW, Timmons JA, Phillips SM.

J Appl Physiol (1985). 2011 Feb;110(2):309-17. doi: 10.1152/japplphysiol.00901.2010. Epub 2010 Oct 28.


A transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype.

Keller P, Vollaard NB, Gustafsson T, Gallagher IJ, Sundberg CJ, Rankinen T, Britton SL, Bouchard C, Koch LG, Timmons JA.

J Appl Physiol (1985). 2011 Jan;110(1):46-59. doi: 10.1152/japplphysiol.00634.2010. Epub 2010 Oct 7.


Integration of microRNA changes in vivo identifies novel molecular features of muscle insulin resistance in type 2 diabetes.

Gallagher IJ, Scheele C, Keller P, Nielsen AR, Remenyi J, Fischer CP, Roder K, Babraj J, Wahlestedt C, Hutvagner G, Pedersen BK, Timmons JA.

Genome Med. 2010 Feb 1;2(2):9. doi: 10.1186/gm130.


Using transcriptomics to identify and validate novel biomarkers of human skeletal muscle cancer cachexia.

Stephens NA, Gallagher IJ, Rooyackers O, Skipworth RJ, Tan BH, Marstrand T, Ross JA, Guttridge DC, Lundell L, Fearon KC, Timmons JA.

Genome Med. 2010 Jan 15;2(1):1. doi: 10.1186/gm122.


Pleural cellular reaction to the filarial infection Litomosoides sigmodontis is determined by the moulting process, the worm alteration, and the host strain.

Attout T, Martin C, Babayan SA, Kozek WJ, Bazzocchi C, Oudet F, Gallagher IJ, Specht S, Bain O.

Parasitol Int. 2008 Jun;57(2):201-11. doi: 10.1016/j.parint.2008.01.001. Epub 2008 Feb 4.


Chitinase and Fizz family members are a generalized feature of nematode infection with selective upregulation of Ym1 and Fizz1 by antigen-presenting cells.

Nair MG, Gallagher IJ, Taylor MD, Loke P, Coulson PS, Wilson RA, Maizels RM, Allen JE.

Infect Immun. 2005 Jan;73(1):385-94.

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