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Items: 1 to 50 of 62

1.

Effects of cardiomyopathy-linked mutations K15N and R21H in tropomyosin on thin-filament regulation and pointed-end dynamics.

Ly T, Pappas CT, Johnson D, Schlecht W, Colpan M, Galkin VE, Gregorio CC, Dong WJ, Kostyukova AS.

Mol Biol Cell. 2019 Jan 15;30(2):268-281. doi: 10.1091/mbc.E18-06-0406. Epub 2018 Nov 21.

2.

N-Terminal Domains of Cardiac Myosin Binding Protein C Cooperatively Activate the Thin Filament.

Risi C, Belknap B, Forgacs-Lonart E, Harris SP, Schröder GF, White HD, Galkin VE.

Structure. 2018 Dec 4;26(12):1604-1611.e4. doi: 10.1016/j.str.2018.08.007. Epub 2018 Sep 27.

PMID:
30270174
3.

Accurate flexible refinement of atomic models against medium-resolution cryo-EM maps using damped dynamics.

Kovacs JA, Galkin VE, Wriggers W.

BMC Struct Biol. 2018 Sep 15;18(1):12. doi: 10.1186/s12900-018-0089-0.

4.

Ca2+-induced movement of tropomyosin on native cardiac thin filaments revealed by cryoelectron microscopy.

Risi C, Eisner J, Belknap B, Heeley DH, White HD, Schröder GF, Galkin VE.

Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):6782-6787. doi: 10.1073/pnas.1700868114. Epub 2017 Jun 12.

5.

Filaments and fingers: Novel structural aspects of the single septin from Chlamydomonas reinhardtii.

Pinto APA, Pereira HM, Zeraik AE, Ciol H, Ferreira FM, Brandão-Neto J, DeMarco R, Navarro MVAS, Risi C, Galkin VE, Garratt RC, Araujo APU.

J Biol Chem. 2017 Jun 30;292(26):10899-10911. doi: 10.1074/jbc.M116.762229. Epub 2017 May 5.

6.

Multimodal and Polymorphic Interactions between Anillin and Actin: Their Implications for Cytokinesis.

Jananji S, Risi C, Lindamulage IKS, Picard LP, Van Sciver R, Laflamme G, Albaghjati A, Hickson GRX, Kwok BH, Galkin VE.

J Mol Biol. 2017 Mar 10;429(5):715-731. doi: 10.1016/j.jmb.2017.01.020. Epub 2017 Jan 29.

PMID:
28147230
7.

C0 and C1 N-terminal Ig domains of myosin binding protein C exert different effects on thin filament activation.

Harris SP, Belknap B, Van Sciver RE, White HD, Galkin VE.

Proc Natl Acad Sci U S A. 2016 Feb 9;113(6):1558-63. doi: 10.1073/pnas.1518891113. Epub 2016 Feb 1.

8.

Septin 9 Exhibits Polymorphic Binding to F-Actin and Inhibits Myosin and Cofilin Activity.

Smith C, Dolat L, Angelis D, Forgacs E, Spiliotis ET, Galkin VE.

J Mol Biol. 2015 Oct 9;427(20):3273-3284. doi: 10.1016/j.jmb.2015.07.026. Epub 2015 Aug 19.

9.

Near-atomic resolution for one state of F-actin.

Galkin VE, Orlova A, Vos MR, Schröder GF, Egelman EH.

Structure. 2015 Jan 6;23(1):173-182. doi: 10.1016/j.str.2014.11.006. Epub 2014 Dec 18.

10.

Septins promote stress fiber-mediated maturation of focal adhesions and renal epithelial motility.

Dolat L, Hunyara JL, Bowen JR, Karasmanis EP, Elgawly M, Galkin VE, Spiliotis ET.

J Cell Biol. 2014 Oct 27;207(2):225-35. doi: 10.1083/jcb.201405050.

11.

Reversible paralysis of Schistosoma mansoni by forchlorfenuron, a phenylurea cytokinin that affects septins.

Zeraik AE, Galkin VE, Rinaldi G, Garratt RC, Smout MJ, Loukas A, Mann VH, Araujo AP, DeMarco R, Brindley PJ.

Int J Parasitol. 2014 Jul;44(8):523-31. doi: 10.1016/j.ijpara.2014.03.010. Epub 2014 Apr 21.

12.

Identification of an actin binding surface on vinculin that mediates mechanical cell and focal adhesion properties.

Thompson PM, Tolbert CE, Shen K, Kota P, Palmer SM, Plevock KM, Orlova A, Galkin VE, Burridge K, Egelman EH, Dokholyan NV, Superfine R, Campbell SL.

Structure. 2014 May 6;22(5):697-706. doi: 10.1016/j.str.2014.03.002. Epub 2014 Mar 27.

13.

The structure of the CS1 pilus of enterotoxigenic Escherichia coli reveals structural polymorphism.

Galkin VE, Kolappan S, Ng D, Zong Z, Li J, Yu X, Egelman EH, Craig L.

J Bacteriol. 2013 Apr;195(7):1360-70. doi: 10.1128/JB.01989-12. Epub 2012 Nov 21.

14.

Are ParM filaments polar or bipolar?

Galkin VE, Orlova A, Egelman EH.

J Mol Biol. 2012 Nov 2;423(4):482-5. doi: 10.1016/j.jmb.2012.08.006. Epub 2012 Aug 21.

15.

Actin filaments as tension sensors.

Galkin VE, Orlova A, Egelman EH.

Curr Biol. 2012 Feb 7;22(3):R96-101. doi: 10.1016/j.cub.2011.12.010. Review.

16.

Remodeling of actin filaments by ADF/cofilin proteins.

Galkin VE, Orlova A, Kudryashov DS, Solodukhin A, Reisler E, Schröder GF, Egelman EH.

Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20568-72. doi: 10.1073/pnas.1110109108. Epub 2011 Dec 7.

17.

The N-terminal domains of myosin binding protein C can bind polymorphically to F-actin.

Orlova A, Galkin VE, Jeffries CM, Egelman EH, Trewhella J.

J Mol Biol. 2011 Sep 23;412(3):379-86. doi: 10.1016/j.jmb.2011.07.056. Epub 2011 Jul 29.

18.

Two modes of binding of DinI to RecA filament provide a new insight into the regulation of SOS response by DinI protein.

Galkin VE, Britt RL, Bane LB, Yu X, Cox MM, Egelman EH.

J Mol Biol. 2011 May 20;408(5):815-24. doi: 10.1016/j.jmb.2011.03.046. Epub 2011 Mar 31.

19.

Structural polymorphism in F-actin.

Galkin VE, Orlova A, Schröder GF, Egelman EH.

Nat Struct Mol Biol. 2010 Nov;17(11):1318-23. doi: 10.1038/nsmb.1930. Epub 2010 Oct 10.

20.

Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.

Dray E, Etchin J, Wiese C, Saro D, Williams GJ, Hammel M, Yu X, Galkin VE, Liu D, Tsai MS, Sy SM, Schild D, Egelman E, Chen J, Sung P.

Nat Struct Mol Biol. 2010 Oct;17(10):1255-9. doi: 10.1038/nsmb.1916. Epub 2010 Sep 26.

21.

Opening of tandem calponin homology domains regulates their affinity for F-actin.

Galkin VE, Orlova A, Salmazo A, Djinovic-Carugo K, Egelman EH.

Nat Struct Mol Biol. 2010 May;17(5):614-6. doi: 10.1038/nsmb.1789. Epub 2010 Apr 11.

22.

Mapping of drebrin binding site on F-actin.

Grintsevich EE, Galkin VE, Orlova A, Ytterberg AJ, Mikati MM, Kudryashov DS, Loo JA, Egelman EH, Reisler E.

J Mol Biol. 2010 May 14;398(4):542-54. doi: 10.1016/j.jmb.2010.03.039. Epub 2010 Mar 27.

23.

ParA2, a Vibrio cholerae chromosome partitioning protein, forms left-handed helical filaments on DNA.

Hui MP, Galkin VE, Yu X, Stasiak AZ, Stasiak A, Waldor MK, Egelman EH.

Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4590-5. doi: 10.1073/pnas.0913060107. Epub 2010 Feb 22.

24.

The structure of the Salmonella typhimurium type III secretion system needle shows divergence from the flagellar system.

Galkin VE, Schmied WH, Schraidt O, Marlovits TC, Egelman EH.

J Mol Biol. 2010 Mar 12;396(5):1392-7. doi: 10.1016/j.jmb.2010.01.001. Epub 2010 Jan 11.

25.

Structural polymorphism of the ParM filament and dynamic instability.

Galkin VE, Orlova A, Rivera C, Mullins RD, Egelman EH.

Structure. 2009 Sep 9;17(9):1253-64. doi: 10.1016/j.str.2009.07.008.

26.

The RecB nuclease domain binds to RecA-DNA filaments: implications for filament loading.

Lucarelli D, Wang YA, Galkin VE, Yu X, Wigley DB, Egelman EH.

J Mol Biol. 2009 Aug 14;391(2):269-74. doi: 10.1016/j.jmb.2009.06.042. Epub 2009 Jun 21.

27.

Loop 2 in Saccharomyces cerevisiae Rad51 protein regulates filament formation and ATPase activity.

Zhang XP, Galkin VE, Yu X, Egelman EH, Heyer WD.

Nucleic Acids Res. 2009 Jan;37(1):158-71. doi: 10.1093/nar/gkn914. Epub 2008 Nov 25.

28.

Cleavage of bacteriophage lambda cI repressor involves the RecA C-terminal domain.

Galkin VE, Yu X, Bielnicki J, Ndjonka D, Bell CE, Egelman EH.

J Mol Biol. 2009 Jan 23;385(3):779-87. doi: 10.1016/j.jmb.2008.10.081. Epub 2008 Nov 5.

29.

Divergence of quaternary structures among bacterial flagellar filaments.

Galkin VE, Yu X, Bielnicki J, Heuser J, Ewing CP, Guerry P, Egelman EH.

Science. 2008 Apr 18;320(5874):382-5. doi: 10.1126/science.1155307.

30.

High-resolution cryo-EM structure of the F-actin-fimbrin/plastin ABD2 complex.

Galkin VE, Orlova A, Cherepanova O, Lebart MC, Egelman EH.

Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1494-8. doi: 10.1073/pnas.0708667105. Epub 2008 Jan 30.

31.

Coronin-1A stabilizes F-actin by bridging adjacent actin protomers and stapling opposite strands of the actin filament.

Galkin VE, Orlova A, Brieher W, Kueh HY, Mitchison TJ, Egelman EH.

J Mol Biol. 2008 Feb 22;376(3):607-13. doi: 10.1016/j.jmb.2007.12.007. Epub 2007 Dec 8.

32.

Actin hydrophobic loop 262-274 and filament nucleation and elongation.

Shvetsov A, Galkin VE, Orlova A, Phillips M, Bergeron SE, Rubenstein PA, Egelman EH, Reisler E.

J Mol Biol. 2008 Jan 18;375(3):793-801. Epub 2007 Nov 4.

33.

The structure of bacterial ParM filaments.

Orlova A, Garner EC, Galkin VE, Heuser J, Mullins RD, Egelman EH.

Nat Struct Mol Biol. 2007 Oct;14(10):921-6. Epub 2007 Sep 16.

34.

Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2.

Esashi F, Galkin VE, Yu X, Egelman EH, West SC.

Nat Struct Mol Biol. 2007 Jun;14(6):468-74. Epub 2007 May 21.

PMID:
17515904
35.

Stabilization of RAD-51-DNA filaments via an interaction domain in Caenorhabditis elegans BRCA2.

Petalcorin MI, Galkin VE, Yu X, Egelman EH, Boulton SJ.

Proc Natl Acad Sci U S A. 2007 May 15;104(20):8299-304. Epub 2007 May 2.

36.

Mapping the interaction of cofilin with subdomain 2 on actin.

Benchaar SA, Xie Y, Phillips M, Loo RR, Galkin VE, Orlova A, Thevis M, Muhlrad A, Almo SC, Loo JA, Egelman EH, Reisler E.

Biochemistry. 2007 Jan 9;46(1):225-33.

PMID:
17198393
37.

The Rad51/RadA N-terminal domain activates nucleoprotein filament ATPase activity.

Galkin VE, Wu Y, Zhang XP, Qian X, He Y, Yu X, Heyer WD, Luo Y, Egelman EH.

Structure. 2006 Jun;14(6):983-92.

38.

The CH-domain of calponin does not determine the modes of calponin binding to F-actin.

Galkin VE, Orlova A, Fattoum A, Walsh MP, Egelman EH.

J Mol Biol. 2006 Jun 2;359(2):478-85. Epub 2006 Apr 3.

PMID:
16626733
39.

Cofilin cross-bridges adjacent actin protomers and replaces part of the longitudinal F-actin interface.

Kudryashov DS, Galkin VE, Orlova A, Phan M, Egelman EH, Reisler E.

J Mol Biol. 2006 May 5;358(3):785-97. Epub 2006 Feb 28.

PMID:
16530787
40.

Xin-repeats and nebulin-like repeats bind to F-actin in a similar manner.

Cherepanova O, Orlova A, Galkin VE, van der Ven PF, Fürst DO, Jin JP, Egelman EH.

J Mol Biol. 2006 Feb 24;356(3):714-23. Epub 2005 Dec 13.

PMID:
16384582
41.

BRCA2 BRC motifs bind RAD51-DNA filaments.

Galkin VE, Esashi F, Yu X, Yang S, West SC, Egelman EH.

Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8537-42. Epub 2005 Jun 3.

42.
43.

The Arg non-receptor tyrosine kinase modifies F-actin structure.

Galkin VE, Orlova A, Koleske AJ, Egelman EH.

J Mol Biol. 2005 Feb 18;346(2):565-75. Epub 2004 Dec 23.

PMID:
15670605
44.

Actin-destabilizing factors disrupt filaments by means of a time reversal of polymerization.

Orlova A, Shvetsov A, Galkin VE, Kudryashov DS, Rubenstein PA, Egelman EH, Reisler E.

Proc Natl Acad Sci U S A. 2004 Dec 21;101(51):17664-8. Epub 2004 Dec 10.

45.

ADF/cofilin use an intrinsic mode of F-actin instability to disrupt actin filaments.

Galkin VE, Orlova A, VanLoock MS, Shvetsov A, Reisler E, Egelman EH.

J Cell Biol. 2003 Dec 8;163(5):1057-66. Epub 2003 Dec 1.

46.

Issues of resolution and polymorphism in single-particle reconstruction.

Yang S, Yu X, Galkin VE, Egelman EH.

J Struct Biol. 2003 Oct-Nov;144(1-2):162-71.

PMID:
14643219
47.

Complexes of RecA with LexA and RecX differentiate between active and inactive RecA nucleoprotein filaments.

VanLoock MS, Yu X, Yang S, Galkin VE, Huang H, Rajan SS, Anderson WF, Stohl EA, Seifert HS, Egelman EH.

J Mol Biol. 2003 Oct 17;333(2):345-54.

PMID:
14529621
48.

Salmonella SipA polymerizes actin by stapling filaments with nonglobular protein arms.

Lilic M, Galkin VE, Orlova A, VanLoock MS, Egelman EH, Stebbins CE.

Science. 2003 Sep 26;301(5641):1918-21.

49.

Do the utrophin tandem calponin homology domains bind F-actin in a compact or extended conformation?

Galkin VE, Orlova A, VanLoock MS, Egelman EH.

J Mol Biol. 2003 Aug 29;331(5):967-72.

PMID:
12927533
50.

Interactions of C-Reactive Protein and Serum Amyloid P Component with Interleukin-8 and Their Role in Regulation of Neutrophil Functions.

Galkina EV, Nazarov PG, Polevschikov AV, Berestovaya LK, Galkin VE, Bychkova NV.

Russ J Immunol. 2000 Dec;5(4):363-374.

PMID:
12687191

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