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Items: 19

1.

Active thrombin produced by the intestinal epithelium controls mucosal biofilms.

Motta JP, Denadai-Souza A, Sagnat D, Guiraud L, Edir A, Bonnart C, Sebbag M, Rousset P, Lapeyre A, Seguy C, Mathurine-Thomas N, Galipeau HJ, Bonnet D, Alric L, Buret AG, Wallace JL, Dufour A, Verdu EF, Hollenberg MD, Oswald E, Serino M, Deraison C, Vergnolle N.

Nat Commun. 2019 Jul 19;10(1):3224. doi: 10.1038/s41467-019-11140-w.

2.

Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2.

Caminero A, McCarville JL, Galipeau HJ, Deraison C, Bernier SP, Constante M, Rolland C, Meisel M, Murray JA, Yu XB, Alaedini A, Coombes BK, Bercik P, Southward CM, Ruf W, Jabri B, Chirdo FG, Casqueiro J, Surette MG, Vergnolle N, Verdu EF.

Nat Commun. 2019 Mar 13;10(1):1198. doi: 10.1038/s41467-019-09037-9.

3.

Lactobacilli Degrade Wheat Amylase Trypsin Inhibitors to Reduce Intestinal Dysfunction Induced by Immunogenic Wheat Proteins.

Caminero A, McCarville JL, Zevallos VF, Pigrau M, Yu XB, Jury J, Galipeau HJ, Clarizio AV, Casqueiro J, Murray JA, Collins SM, Alaedini A, Bercik P, Schuppan D, Verdu EF.

Gastroenterology. 2019 Jun;156(8):2266-2280. doi: 10.1053/j.gastro.2019.02.028. Epub 2019 Feb 22.

PMID:
30802444
4.

Celiac Disease: A Review of Current Concepts in Pathogenesis, Prevention, and Novel Therapies.

Tye-Din JA, Galipeau HJ, Agardh D.

Front Pediatr. 2018 Nov 21;6:350. doi: 10.3389/fped.2018.00350. eCollection 2018. Review.

5.

Commensal microbiota induces colonic barrier structure and functions that contribute to homeostasis.

Hayes CL, Dong J, Galipeau HJ, Jury J, McCarville J, Huang X, Wang XY, Naidoo A, Anbazhagan AN, Libertucci J, Sheridan C, Dudeja PK, Bowdish DME, Surette MG, Verdu EF.

Sci Rep. 2018 Sep 21;8(1):14184. doi: 10.1038/s41598-018-32366-6.

6.

An intact microbiota is required for the gastrointestinal toxicity of the immunosuppressant mycophenolate mofetil.

Flannigan KL, Taylor MR, Pereira SK, Rodriguez-Arguello J, Moffat AW, Alston L, Wang X, Poon KK, Beck PL, Rioux KP, Jonnalagadda M, Chelikani PK, Galipeau HJ, Lewis IA, Workentine ML, Greenway SC, Hirota SA.

J Heart Lung Transplant. 2018 Sep;37(9):1047-1059. doi: 10.1016/j.healun.2018.05.002. Epub 2018 May 23.

PMID:
30173823
7.

Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.

Meisel M, Hinterleitner R, Pacis A, Chen L, Earley ZM, Mayassi T, Pierre JF, Ernest JD, Galipeau HJ, Thuille N, Bouziat R, Buscarlet M, Ringus DL, Wang Y, Li Y, Dinh V, Kim SM, McDonald BD, Zurenski MA, Musch MW, Furtado GC, Lira SA, Baier G, Chang EB, Eren AM, Weber CR, Busque L, Godley LA, Verdú EF, Barreiro LB, Jabri B.

Nature. 2018 May;557(7706):580-584. doi: 10.1038/s41586-018-0125-z. Epub 2018 May 16.

8.

Lifelong memory responses perpetuate humoral TH2 immunity and anaphylaxis in food allergy.

Jiménez-Saiz R, Chu DK, Mandur TS, Walker TD, Gordon ME, Chaudhary R, Koenig J, Saliba S, Galipeau HJ, Utley A, King IL, Lee K, Ettinger R, Waserman S, Kolbeck R, Jordana M.

J Allergy Clin Immunol. 2017 Dec;140(6):1604-1615.e5. doi: 10.1016/j.jaci.2017.01.018. Epub 2017 Feb 16.

9.

Duodenal Bacteria From Patients With Celiac Disease and Healthy Subjects Distinctly Affect Gluten Breakdown and Immunogenicity.

Caminero A, Galipeau HJ, McCarville JL, Johnston CW, Bernier SP, Russell AK, Jury J, Herran AR, Casqueiro J, Tye-Din JA, Surette MG, Magarvey NA, Schuppan D, Verdu EF.

Gastroenterology. 2016 Oct;151(4):670-83. doi: 10.1053/j.gastro.2016.06.041. Epub 2016 Jun 30.

PMID:
27373514
10.

The complex task of measuring intestinal permeability in basic and clinical science.

Galipeau HJ, Verdu EF.

Neurogastroenterol Motil. 2016 Jul;28(7):957-65. doi: 10.1111/nmo.12871. Review.

PMID:
27339216
11.

Intestinal microbiota modulates gluten-induced immunopathology in humanized mice.

Galipeau HJ, McCarville JL, Huebener S, Litwin O, Meisel M, Jabri B, Sanz Y, Murray JA, Jordana M, Alaedini A, Chirdo FG, Verdu EF.

Am J Pathol. 2015 Nov;185(11):2969-82. doi: 10.1016/j.ajpath.2015.07.018. Epub 2015 Oct 9.

12.

Ecobiotherapy Rich in Firmicutes Decreases Susceptibility to Colitis in a Humanized Gnotobiotic Mouse Model.

Natividad JM, Pinto-Sanchez MI, Galipeau HJ, Jury J, Jordana M, Reinisch W, Collins SM, Bercik P, Surette MG, Allen-Vercoe E, Verdu EF.

Inflamm Bowel Dis. 2015 Aug;21(8):1883-93. doi: 10.1097/MIB.0000000000000422.

PMID:
26060932
13.

Novel players in coeliac disease pathogenesis: role of the gut microbiota.

Verdu EF, Galipeau HJ, Jabri B.

Nat Rev Gastroenterol Hepatol. 2015 Sep;12(9):497-506. doi: 10.1038/nrgastro.2015.90. Epub 2015 Jun 9. Review.

14.

Gut microbes and adverse food reactions: Focus on gluten related disorders.

Galipeau HJ, Verdu EF.

Gut Microbes. 2014;5(5):594-605. doi: 10.4161/19490976.2014.969635. Review.

15.

BL-7010 demonstrates specific binding to gliadin and reduces gluten-associated pathology in a chronic mouse model of gliadin sensitivity.

McCarville JL, Nisemblat Y, Galipeau HJ, Jury J, Tabakman R, Cohen A, Naftali E, Neiman B, Halbfinger E, Murray JA, Anbazhagan AN, Dudeja PK, Varvak A, Leroux JC, Verdu EF.

PLoS One. 2014 Nov 3;9(11):e109972. doi: 10.1371/journal.pone.0109972. eCollection 2014.

16.

Novel role of the serine protease inhibitor elafin in gluten-related disorders.

Galipeau HJ, Wiepjes M, Motta JP, Schulz JD, Jury J, Natividad JM, Pinto-Sanchez I, Sinclair D, Rousset P, Martin-Rosique R, Bermudez-Humaran L, Leroux JC, Murray JA, Smecuol E, Bai JC, Vergnolle N, Langella P, Verdu EF.

Am J Gastroenterol. 2014 May;109(5):748-56. doi: 10.1038/ajg.2014.48. Epub 2014 Apr 8.

17.

Differential induction of antimicrobial REGIII by the intestinal microbiota and Bifidobacterium breve NCC2950.

Natividad JM, Hayes CL, Motta JP, Jury J, Galipeau HJ, Philip V, Garcia-Rodenas CL, Kiyama H, Bercik P, Verdu EF.

Appl Environ Microbiol. 2013 Dec;79(24):7745-54. doi: 10.1128/AEM.02470-13. Epub 2013 Oct 4.

18.

The copolymer P(HEMA-co-SS) binds gluten and reduces immune response in gluten-sensitized mice and human tissues.

Pinier M, Fuhrmann G, Galipeau HJ, Rivard N, Murray JA, David CS, Drasarova H, Tuckova L, Leroux JC, Verdu EF.

Gastroenterology. 2012 Feb;142(2):316-25.e1-12. doi: 10.1053/j.gastro.2011.10.038. Epub 2011 Nov 10.

PMID:
22079593
19.

Sensitization to gliadin induces moderate enteropathy and insulitis in nonobese diabetic-DQ8 mice.

Galipeau HJ, Rulli NE, Jury J, Huang X, Araya R, Murray JA, David CS, Chirdo FG, McCoy KD, Verdu EF.

J Immunol. 2011 Oct 15;187(8):4338-46. doi: 10.4049/jimmunol.1100854. Epub 2011 Sep 12.

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