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Items: 1 to 20 of 90

1.

Regulation of FKBP51 and FKBP52 functions by post-translational modifications.

Daneri-Becerra C, Zgajnar NR, Lotufo CM, Ramos Hryb AB, Piwien-Pilipuk G, Galigniana MD.

Biochem Soc Trans. 2019 Nov 22. pii: BST20190334. doi: 10.1042/BST20190334. [Epub ahead of print]

PMID:
31754722
2.

Rational Identification of Hsp90 Inhibitors as Anticancer Lead Molecules by Structure Based Drug Designing Approach.

Gupta SD, Swapanthi PS, Bhagya D, Federicci F, Mazaira GI, Galigniana MD, Subrahmanyam CVS, Gowrishankar NL, Raghavendra NM.

Anticancer Agents Med Chem. 2019 Nov 11. doi: 10.2174/1871520619666191111152050. [Epub ahead of print]

PMID:
31713499
3.

Reconstitution of the Steroid Receptor Heterocomplex.

Mazaira GI, Galigniana MD.

Methods Mol Biol. 2019;1966:125-135. doi: 10.1007/978-1-4939-9195-2_10.

PMID:
31041743
4.

Nuclear Receptors: A Historical Perspective.

Mazaira GI, Zgajnar NR, Lotufo CM, Daneri-Becerra C, Sivils JC, Soto OB, Cox MB, Galigniana MD.

Methods Mol Biol. 2019;1966:1-5. doi: 10.1007/978-1-4939-9195-2_1.

PMID:
31041734
5.

Heme Oxygenase 1 Impairs Glucocorticoid Receptor Activity in Prostate Cancer.

Leonardi DB, Anselmino N, Brandani JN, Jaworski FM, Páez AV, Mazaira G, Meiss RP, Nuñez M, Nemirovsky SI, Giudice J, Galigniana M, Pecci A, Gueron G, Vazquez E, Cotignola J.

Int J Mol Sci. 2019 Feb 26;20(5). pii: E1006. doi: 10.3390/ijms20051006.

6.

Biological Actions of the Hsp90-binding Immunophilins FKBP51 and FKBP52

Zgajnar NR, De Leo SA, Lotufo CM, Erlejman AG, Piwien-Pilipuk G, Galigniana MD.

Biomolecules. 2019 Feb 1;9(2). pii: E52. doi: 10.3390/biom9020052. Review.

7.

Fe3 O4 nanoparticles mediated synthesis of novel spirooxindole-dihydropyrimidinone molecules as Hsp90 inhibitors.

Maddela S, Makula A, Galigniana MD, Parambi DGT, Federicci F, Mazaira G, Hendawy OM, Dev S, Mathew GE, Mathew B.

Arch Pharm (Weinheim). 2019 Jan;352(1):e1800174. doi: 10.1002/ardp.201800174. Epub 2018 Nov 28.

PMID:
30485473
8.

The Nuclear Receptor Field: A Historical Overview and Future Challenges.

Mazaira GI, Zgajnar NR, Lotufo CM, Daneri-Becerra C, Sivils JC, Soto OB, Cox MB, Galigniana MD.

Nucl Receptor Res. 2018;5. pii: 101320. doi: 10.11131/2018/101320. Epub 2018 Jul 26.

9.

Gene expression regulation by heat-shock proteins: the cardinal roles of HSF1 and Hsp90.

Mazaira GI, Daneri-Becerra C, Zgajnar NR, Lotufo CM, Galigniana MD.

Biochem Soc Trans. 2018 Feb 19;46(1):51-65. doi: 10.1042/BST20170335. Epub 2017 Dec 22. Review.

PMID:
29273620
10.

Functional interaction between co-expressed MAGE-A proteins.

Laiseca JE, Ladelfa MF, Cotignola J, Peche LY, Pascucci FA, Castaño BA, Galigniana MD, Schneider C, Monte M.

PLoS One. 2017 May 24;12(5):e0178370. doi: 10.1371/journal.pone.0178370. eCollection 2017.

11.

Hsp90-binding immunophilin FKBP51 forms complexes with hTERT enhancing telomerase activity.

Lagadari M, Zgajnar NR, Gallo LI, Galigniana MD.

Mol Oncol. 2016 Aug;10(7):1086-98. doi: 10.1016/j.molonc.2016.05.002. Epub 2016 May 17.

12.

Editorial: Immunophilins, Protein Chemistry and Cell Biology of a Promising New Class of Drug Targets - Part II.

Galigniana MD.

Curr Mol Pharmacol. 2016;9(2):97-8. No abstract available.

PMID:
26654092
13.

Editorial: Immunophilins, Protein Chemistry and Cell Biology of a Promising New Class of Drug Targets - Part I.

Galigniana MD.

Curr Mol Pharmacol. 2015;9(1):3-4. No abstract available.

PMID:
26653049
14.

Synthetic stigmastanes with dual antiherpetic and immunomodulating activities inhibit ERK and Akt signaling pathways without binding to glucocorticoid receptors.

Michelini FM, Bueno CA, Molinari AM, Galigniana MD, Galagovsky LR, Alché LE, Ramírez JA.

Biochim Biophys Acta. 2016 Jan;1860(1 Pt A):129-39. doi: 10.1016/j.bbagen.2015.10.024. Epub 2015 Oct 28.

PMID:
26518349
15.

Synthetic pregnenolone derivatives as antiviral agents against acyclovir-resistant isolates of Herpes Simplex Virus Type 1.

Dávola ME, Mazaira GI, Galigniana MD, Alché LE, Ramírez JA, Barquero AA.

Antiviral Res. 2015 Oct;122:55-63. doi: 10.1016/j.antiviral.2015.08.002. Epub 2015 Aug 8.

PMID:
26259812
16.

Molecular docking study, synthesis and biological evaluation of Mannich bases as Hsp90 inhibitors.

Dutta Gupta S, Bommaka MK, Mazaira GI, Galigniana MD, Subrahmanyam CV, Gowrishankar NL, Raghavendra NM.

Int J Biol Macromol. 2015 Sep;80:253-9. doi: 10.1016/j.ijbiomac.2015.06.039. Epub 2015 Jun 24.

PMID:
26116388
17.

Regulation of NF-κB signalling cascade by immunophilins.

Lagadari M, De Leo SA, Camisay MF, Galigniana MD, Erlejman AG.

Curr Mol Pharmacol. 2016;9(2):99-108. Review.

PMID:
25986566
18.

Biological relevance of Hsp90-binding immunophilins in cancer development and treatment.

Mazaira GI, Camisay MF, De Leo S, Erlejman AG, Galigniana MD.

Int J Cancer. 2016 Feb 15;138(4):797-808. doi: 10.1002/ijc.29509. Epub 2015 Mar 24. Review.

19.

2,4-dihydroxy benzaldehyde derived Schiff bases as small molecule Hsp90 inhibitors: rational identification of a new anticancer lead.

Dutta Gupta S, Revathi B, Mazaira GI, Galigniana MD, Subrahmanyam CV, Gowrishankar NL, Raghavendra NM.

Bioorg Chem. 2015 Apr;59:97-105. doi: 10.1016/j.bioorg.2015.02.003. Epub 2015 Feb 14.

PMID:
25727264
20.

Functions of the Hsp90-binding FKBP immunophilins.

Guy NC, Garcia YA, Sivils JC, Galigniana MD, Cox MB.

Subcell Biochem. 2015;78:35-68. doi: 10.1007/978-3-319-11731-7_2. Review.

PMID:
25487015

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