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Personality traits and risk of suicide mortality: findings from a multi-cohort study in the general population.

David Batty G, Gale CR, Tanji F, Gunnell D, Kivimäki M, Tsuji I, Jokela M.

World Psychiatry. 2018 Oct;17(3):371-372. doi: 10.1002/wps.20575. No abstract available.


Intelligence in youth and health behaviours in middle age.

Wraw C, Der G, Gale CR, Deary IJ.

Intelligence. 2018 Jul-Aug;69:71-86. doi: 10.1016/j.intell.2018.04.005.


DNA methylation and the epigenetic clock in relation to physical frailty in older people: the Lothian Birth Cohort 1936.

Gale CR, Marioni RE, Harris SE, Starr JM, Deary IJ.

Clin Epigenetics. 2018 Aug 3;10(1):101. doi: 10.1186/s13148-018-0538-4.


Pain is not associated with cognitive decline in older adults: A four-year longitudinal study.

Veronese N, Koyanagi A, Solmi M, Thompson T, Maggi S, Schofield P, Mueller C, Gale CR, Cooper C, Stubbs B.

Maturitas. 2018 Sep;115:92-96. doi: 10.1016/j.maturitas.2018.07.001. Epub 2018 Jul 3.


Genetic risk for neurodegenerative disorders, and its overlap with cognitive ability and physical function.

Hagenaars SP, Radaković R, Crockford C, Fawns-Ritchie C; International FTD-Genomics Consortium (IFGC), Harris SE, Gale CR, Deary IJ.

PLoS One. 2018 Jun 1;13(6):e0198187. doi: 10.1371/journal.pone.0198187. eCollection 2018.


Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoumaki S, Giddaluru S, Gustavson DE, Hayward C, Hofer E, Ikram MA, Karlsson R, Knowles E, Lahti J, Leber M, Li S, Mather KA, Melle I, Morris D, Oldmeadow C, Palviainen T, Payton A, Pazoki R, Petrovic K, Reynolds CA, Sargurupremraj M, Scholz M, Smith JA, Smith AV, Terzikhan N, Thalamuthu A, Trompet S, van der Lee SJ, Ware EB, Windham BG, Wright MJ, Yang J, Yu J, Ames D, Amin N, Amouyel P, Andreassen OA, Armstrong NJ, Assareh AA, Attia JR, Attix D, Avramopoulos D, Bennett DA, Böhmer AC, Boyle PA, Brodaty H, Campbell H, Cannon TD, Cirulli ET, Congdon E, Conley ED, Corley J, Cox SR, Dale AM, Dehghan A, Dick D, Dickinson D, Eriksson JG, Evangelou E, Faul JD, Ford I, Freimer NA, Gao H, Giegling I, Gillespie NA, Gordon SD, Gottesman RF, Griswold ME, Gudnason V, Harris TB, Hartmann AM, Hatzimanolis A, Heiss G, Holliday EG, Joshi PK, Kähönen M, Kardia SLR, Karlsson I, Kleineidam L, Knopman DS, Kochan NA, Konte B, Kwok JB, Le Hellard S, Lee T, Lehtimäki T, Li SC, Liu T, Koini M, London E, Longstreth WT Jr, Lopez OL, Loukola A, Luck T, Lundervold AJ, Lundquist A, Lyytikäinen LP, Martin NG, Montgomery GW, Murray AD, Need AC, Noordam R, Nyberg L, Ollier W, Papenberg G, Pattie A, Polasek O, Poldrack RA, Psaty BM, Reppermund S, Riedel-Heller SG, Rose RJ, Rotter JI, Roussos P, Rovio SP, Saba Y, Sabb FW, Sachdev PS, Satizabal CL, Schmid M, Scott RJ, Scult MA, Simino J, Slagboom PE, Smyrnis N, Soumaré A, Stefanis NC, Stott DJ, Straub RE, Sundet K, Taylor AM, Taylor KD, Tzoulaki I, Tzourio C, Uitterlinden A, Vitart V, Voineskos AN, Kaprio J, Wagner M, Wagner H, Weinhold L, Wen KH, Widen E, Yang Q, Zhao W, Adams HHH, Arking DE, Bilder RM, Bitsios P, Boerwinkle E, Chiba-Falek O, Corvin A, De Jager PL, Debette S, Donohoe G, Elliott P, Fitzpatrick AL, Gill M, Glahn DC, Hägg S, Hansell NK, Hariri AR, Ikram MK, Jukema JW, Vuoksimaa E, Keller MC, Kremen WS, Launer L, Lindenberger U, Palotie A, Pedersen NL, Pendleton N, Porteous DJ, Räikkönen K, Raitakari OT, Ramirez A, Reinvang I, Rudan I, Dan Rujescu, Schmidt R, Schmidt H, Schofield PW, Schofield PR, Starr JM, Steen VM, Trollor JN, Turner ST, Van Duijn CM, Villringer A, Weinberger DR, Weir DR, Wilson JF, Malhotra A, McIntosh AM, Gale CR, Seshadri S, Mosley TH Jr, Bressler J, Lencz T, Deary IJ.

Nat Commun. 2018 May 29;9(1):2098. doi: 10.1038/s41467-018-04362-x.


GWAS on family history of Alzheimer's disease.

Marioni RE, Harris SE, Zhang Q, McRae AF, Hagenaars SP, Hill WD, Davies G, Ritchie CW, Gale CR, Starr JM, Goate AM, Porteous DJ, Yang J, Evans KL, Deary IJ, Wray NR, Visscher PM.

Transl Psychiatry. 2018 May 18;8(1):99. doi: 10.1038/s41398-018-0150-6.


Sex Differences in the Adult Human Brain: Evidence from 5216 UK Biobank Participants.

Ritchie SJ, Cox SR, Shen X, Lombardo MV, Reus LM, Alloza C, Harris MA, Alderson HL, Hunter S, Neilson E, Liewald DCM, Auyeung B, Whalley HC, Lawrie SM, Gale CR, Bastin ME, McIntosh AM, Deary IJ.

Cereb Cortex. 2018 Aug 1;28(8):2959-2975. doi: 10.1093/cercor/bhy109.


Risk factors for incident falls in older men and women: the English longitudinal study of ageing.

Gale CR, Westbury LD, Cooper C, Dennison EM.

BMC Geriatr. 2018 May 16;18(1):117. doi: 10.1186/s12877-018-0806-3.


Attitudes to ageing and objectively-measured sedentary and walking behaviour in older people: The Lothian Birth Cohort 1936.

Gale CR, Čukić I, Chastin SF, Dall PM, Dontje ML, Skelton DA, Deary IJ; Seniors USP Team.

PLoS One. 2018 May 16;13(5):e0197357. doi: 10.1371/journal.pone.0197357. eCollection 2018.


Preconception Maternal Iodine Status Is Positively Associated with IQ but Not with Measures of Executive Function in Childhood.

Robinson SM, Crozier SR, Miles EA, Gale CR, Calder PC, Cooper C, Inskip HM, Godfrey KM.

J Nutr. 2018 Jun 1;148(6):959-966. doi: 10.1093/jn/nxy054.


Arachidonic acid and DHA status in pregnant women is not associated with cognitive performance of their children at 4 or 6-7 years.

Crozier SR, Sibbons CM, Fisk HL, Godfrey KM, Calder PC, Gale CR, Robinson SM, Inskip HM, Baird J, Harvey NC, Cooper C, Burdge GC; Southampton Women’s Survey (SWS) Study Group.

Br J Nutr. 2018 Jun;119(12):1400-1407. doi: 10.1017/S0007114518000806. Epub 2018 May 8.


Mild cognitive impairment is associated with poor physical function but not bone structure or density in late adulthood: findings from the Hertfordshire cohort study.

Patel A, Jameson KA, Edwards MH, Ward K, Gale CR, Cooper C, Dennison EM.

Arch Osteoporos. 2018 Apr 24;13(1):44. doi: 10.1007/s11657-018-0455-3.


The effects of psychological distress and its interaction with socioeconomic position on risk of developing four chronic diseases.

McLachlan KJJ, Gale CR.

J Psychosom Res. 2018 Jun;109:79-85. doi: 10.1016/j.jpsychores.2018.04.004. Epub 2018 Apr 14.


Cognitive ability does not predict objectively measured sedentary behavior: Evidence from three older cohorts.

Čukić I, Shaw R, Der G, Chastin SFM, Dontje ML, Gill JMR, Starr JM, Skelton DA, Radaković R, Cox SR, Dall PM, Gale CR, Deary IJ.

Psychol Aging. 2018 Mar;33(2):288-296. doi: 10.1037/pag0000221.


Maternal and offspring intelligence in relation to BMI across childhood and adolescence.

Wraw C, Deary IJ, Der G, Gale CR.

Int J Obes (Lond). 2018 Jan 30. doi: 10.1038/s41366-018-0009-1. [Epub ahead of print]


Systematic comparative validation of self-report measures of sedentary time against an objective measure of postural sitting (activPAL).

Chastin SFM, Dontje ML, Skelton DA, Čukić I, Shaw RJ, Gill JMR, Greig CA, Gale CR, Deary IJ, Der G, Dall PM; Seniors USP team.

Int J Behav Nutr Phys Act. 2018 Feb 26;15(1):21. doi: 10.1186/s12966-018-0652-x.


Psychosocial characteristics as potential predictors of suicide in adults: an overview of the evidence with new results from prospective cohort studies.

Batty GD, Kivimäki M, Bell S, Gale CR, Shipley M, Whitley E, Gunnell D.

Transl Psychiatry. 2018 Jan 22;8(1):22. doi: 10.1038/s41398-017-0072-8. Review.


A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.

Hill WD, Marioni RE, Maghzian O, Ritchie SJ, Hagenaars SP, McIntosh AM, Gale CR, Davies G, Deary IJ.

Mol Psychiatry. 2018 Jan 11. doi: 10.1038/s41380-017-0001-5. [Epub ahead of print]


The epigenetic clock and objectively measured sedentary and walking behavior in older adults: the Lothian Birth Cohort 1936.

Gale CR, Marioni RE, Čukić I, Chastin SF, Dall PM, Dontje ML, Skelton DA, Deary IJ; Seniors USP Team.

Clin Epigenetics. 2018 Jan 8;10:4. doi: 10.1186/s13148-017-0438-z. eCollection 2018.


Social isolation and loneliness as risk factors for the progression of frailty: the English Longitudinal Study of Ageing.

Gale CR, Westbury L, Cooper C.

Age Ageing. 2018 May 1;47(3):392-397. doi: 10.1093/ageing/afx188.


Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.

Luciano M, Hagenaars SP, Davies G, Hill WD, Clarke TK, Shirali M, Harris SE, Marioni RE, Liewald DC, Fawns-Ritchie C, Adams MJ, Howard DM, Lewis CM, Gale CR, McIntosh AM, Deary IJ.

Nat Genet. 2018 Jan;50(1):6-11. doi: 10.1038/s41588-017-0013-8. Epub 2017 Dec 18.


Correlates of Level and Loss of Grip Strength in Later Life: Findings from the English Longitudinal Study of Ageing and the Hertfordshire Cohort Study.

Syddall HE, Westbury LD, Shaw SC, Dennison EM, Cooper C, Gale CR.

Calcif Tissue Int. 2018 Jan;102(1):53-63. doi: 10.1007/s00223-017-0337-5. Epub 2017 Oct 22.


Genetic contributions to Trail Making Test performance in UK Biobank.

Hagenaars SP, Cox SR, Hill WD, Davies G, Liewald DCM; CHARGE consortium Cognitive Working Group, Harris SE, McIntosh AM, Gale CR, Deary IJ.

Mol Psychiatry. 2018 Jul;23(7):1575-1583. doi: 10.1038/mp.2017.189. Epub 2017 Sep 19.


Attitudes to Ageing and Change in Frailty Status: The English Longitudinal Study of Ageing.

Gale CR, Cooper C.

Gerontology. 2018;64(1):58-66. doi: 10.1159/000477169. Epub 2017 Aug 23.


The interaction between stress and positive affect in predicting mortality.

Okely JA, Weiss A, Gale CR.

J Psychosom Res. 2017 Sep;100:53-60. doi: 10.1016/j.jpsychores.2017.07.005. Epub 2017 Jul 8.


Wellbeing and chronic lung disease incidence: The Survey of Health, Ageing and Retirement in Europe.

Okely JA, Shaheen SO, Weiss A, Gale CR.

PLoS One. 2017 Jul 20;12(7):e0181320. doi: 10.1371/journal.pone.0181320. eCollection 2017.


The interaction between individualism and wellbeing in predicting mortality: Survey of Health Ageing and Retirement in Europe.

Okely JA, Weiss A, Gale CR.

J Behav Med. 2018 Feb;41(1):1-11. doi: 10.1007/s10865-017-9871-x. Epub 2017 Jul 15.


When Is Higher Neuroticism Protective Against Death? Findings From UK Biobank.

Gale CR, Čukić I, Batty GD, McIntosh AM, Weiss A, Deary IJ.

Psychol Sci. 2017 Sep;28(9):1345-1357. doi: 10.1177/0956797617709813. Epub 2017 Jul 13.


Relationships between socioeconomic position and objectively measured sedentary behaviour in older adults in three prospective cohorts.

Shaw RJ, Čukić I, Deary IJ, Gale CR, Chastin SF, Dall PM, Skelton DA, Der G; Seniors USP Team.

BMJ Open. 2017 Jun 15;7(6):e016436. doi: 10.1136/bmjopen-2017-016436.


Well-Being and Arthritis Incidence: The Role of Inflammatory Mechanisms. Findings From the English Longitudinal Study of Ageing.

Okely JA, Weiss A, Gale CR.

Psychosom Med. 2017 Sep;79(7):742-748. doi: 10.1097/PSY.0000000000000480.


Cognitive ability and physical health: a Mendelian randomization study.

Hagenaars SP, Gale CR, Deary IJ, Harris SE.

Sci Rep. 2017 Jun 1;7(1):2651. doi: 10.1038/s41598-017-02837-3.


The Influence of Neighbourhoods and the Social Environment on Sedentary Behaviour in Older Adults in Three Prospective Cohorts.

Shaw RJ, Čukić I, Deary IJ, Gale CR, Chastin SFM, Dall PM, Dontje ML, Skelton DA, Macdonald L, Der G.

Int J Environ Res Public Health. 2017 May 24;14(6). pii: E557. doi: 10.3390/ijerph14060557.


Association between maternal vitamin D status during pregnancy and offspring cognitive function during childhood and adolescence.

Veena SR, Krishnaveni GV, Srinivasan K, Thajna KP, Hegde BG, Gale CR, Fall CH.

Asia Pac J Clin Nutr. 2017 May;26(3):438-449. doi: 10.6133/apjcn.032016.07.


Intelligence and neuroticism in relation to depression and psychological distress: Evidence from two large population cohorts.

Navrady LB, Ritchie SJ, Chan SWY, Kerr DM, Adams MJ, Hawkins EH, Porteous D, Deary IJ, Gale CR, Batty GD, McIntosh AM.

Eur Psychiatry. 2017 Jun;43:58-65. doi: 10.1016/j.eurpsy.2016.12.012. Epub 2017 Jan 17.


Genetic contributions to self-reported tiredness.

Deary V, Hagenaars SP, Harris SE, Hill WD, Davies G, Liewald DCM; International Consortium for Blood Pressure GWAS; CHARGE consortium Aging and Longevity Group; CHARGE consortium Inflammation Group, McIntosh AM, Gale CR, Deary IJ.

Mol Psychiatry. 2018 Mar;23(3):789-790. doi: 10.1038/mp.2017.70. Epub 2017 Mar 21.


Cognitive Ability in Late Life and Onset of Physical Frailty: The Lothian Birth Cohort 1936.

Gale CR, Ritchie SJ, Cooper C, Starr JM, Deary IJ.

J Am Geriatr Soc. 2017 Jun;65(6):1289-1295. doi: 10.1111/jgs.14787. Epub 2017 Mar 1.


Genetic prediction of male pattern baldness.

Hagenaars SP, Hill WD, Harris SE, Ritchie SJ, Davies G, Liewald DC, Gale CR, Porteous DJ, Deary IJ, Marioni RE.

PLoS Genet. 2017 Feb 14;13(2):e1006594. doi: 10.1371/journal.pgen.1006594. eCollection 2017 Feb.


Genetic contributions to self-reported tiredness.

Deary V, Hagenaars SP, Harris SE, Hill WD, Davies G, Liewald DCM; International Consortium for Blood Pressure GWAS; CHARGE Consortium Aging and Longevity Group; CHARGE Consortium Inflammation Group, McIntosh AM, Gale CR, Deary IJ.

Mol Psychiatry. 2018 Mar;23(3):609-620. doi: 10.1038/mp.2017.5. Epub 2017 Feb 14. Erratum in: Mol Psychiatry. 2018 Mar;23 (3):789-790.


Frailty, prefrailty and employment outcomes in Health and Employment After Fifty (HEAF) Study.

Palmer KT, D'Angelo S, Harris EC, Linaker C, Gale CR, Evandrou M, Syddall H, van Staa T, Cooper C, Aihie Sayer A, Coggon D, Walker-Bone K.

Occup Environ Med. 2017 Jul;74(7):476-482. doi: 10.1136/oemed-2016-104103. Epub 2017 Jan 6.


Associations between perceived neighbourhood problems and quality of life in older adults with and without osteoarthritis: Results from the Hertfordshire Cohort Study.

Timmermans EJ, van der Pas S, Schaap LA, Cooper C, Edwards MH, Gale CR, Deeg DJ, Dennison EM.

Health Place. 2017 Jan;43:144-150. doi: 10.1016/j.healthplace.2016.11.013. Epub 2017 Jan 3.


Sleep disturbance and the older worker: findings from the Health and Employment after Fifty study.

Palmer KT, D'Angelo S, Harris EC, Linaker C, Sayer AA, Gale CR, Evandrou M, van Staa T, Cooper C, Coggon D.

Scand J Work Environ Health. 2017 Mar 1;43(2):136-145. doi: 10.5271/sjweh.3618. Epub 2017 Jan 4.


Ageing and brain white matter structure in 3,513 UK Biobank participants.

Cox SR, Ritchie SJ, Tucker-Drob EM, Liewald DC, Hagenaars SP, Davies G, Wardlaw JM, Gale CR, Bastin ME, Deary IJ.

Nat Commun. 2016 Dec 15;7:13629. doi: 10.1038/ncomms13629.


Molecular genetic aetiology of general cognitive function is enriched in evolutionarily conserved regions.

Hill WD, Davies G, Harris SE, Hagenaars SP; neuroCHARGE Cognitive Working group, Liewald DC, Penke L, Gale CR, Deary IJ.

Transl Psychiatry. 2016 Dec 13;6(12):e980. doi: 10.1038/tp.2016.246.


Molecular genetic contributions to self-rated health.

Harris SE, Hagenaars SP, Davies G, David Hill W, Liewald DCM, Ritchie SJ, Marioni RE; METASTROKE Consortium, International Consortium for Blood Pressure Genome-Wide Association Studies; International Consortium for Blood Pressure Genome-Wide Association Studies; CHARGE Consortium Aging and Longevity Group; CHARGE Consortium Cognitive Group, Sudlow CLM, Wardlaw JM, McIntosh AM, Gale CR, Deary IJ.

Int J Epidemiol. 2017 Jun 1;46(3):994-1009. doi: 10.1093/ije/dyw219.


Molecular Genetic Contributions to Social Deprivation and Household Income in UK Biobank.

Hill WD, Hagenaars SP, Marioni RE, Harris SE, Liewald DCM, Davies G, Okbay A, McIntosh AM, Gale CR, Deary IJ.

Curr Biol. 2016 Nov 21;26(22):3083-3089. doi: 10.1016/j.cub.2016.09.035. Epub 2016 Nov 3.


Genetic variants linked to education predict longevity.

Marioni RE, Ritchie SJ, Joshi PK, Hagenaars SP, Okbay A, Fischer K, Adams MJ, Hill WD, Davies G; Social Science Genetic Association Consortium, Nagy R, Amador C, Läll K, Metspalu A, Liewald DC, Campbell A, Wilson JF, Hayward C, Esko T, Porteous DJ, Gale CR, Deary IJ.

Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):13366-13371. Epub 2016 Oct 31.


Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci.

Smith DJ, Escott-Price V, Davies G, Bailey ME, Colodro-Conde L, Ward J, Vedernikov A, Marioni R, Cullen B, Lyall D, Hagenaars SP, Liewald DC, Luciano M, Gale CR, Ritchie SJ, Hayward C, Nicholl B, Bulik-Sullivan B, Adams M, Couvy-Duchesne B, Graham N, Mackay D, Evans J, Smith BH, Porteous DJ, Medland SE, Martin NG, Holmans P, McIntosh AM, Pell JP, Deary IJ, O'Donovan MC.

Mol Psychiatry. 2016 Nov;21(11):1644. doi: 10.1038/mp.2016.177. Epub 2016 Sep 13. No abstract available.


Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia.

Hagenaars SP, Harris SE, Davies G, Hill WD, Liewald DC, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Cullen B, Malik R; METASTROKE Consortium, International Consortium for Blood Pressure GWAS; SpiroMeta Consortium; CHARGE Consortium Pulmonary Group, CHARGE Consortium Aging and Longevity Group, Worrall BB, Sudlow CL, Wardlaw JM, Gallacher J, Pell J, McIntosh AM, Smith DJ, Gale CR, Deary IJ.

Mol Psychiatry. 2016 Nov;21(11):1624-1632. doi: 10.1038/mp.2015.225. Epub 2016 Jan 26.


Influences on diet quality in older age: the importance of social factors.

Bloom I, Edwards M, Jameson KA, Syddall HE, Dennison E, Gale CR, Baird J, Cooper C, Aihie Sayer A, Robinson S.

Age Ageing. 2017 Mar 1;46(2):277-283. doi: 10.1093/ageing/afw180.

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