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Items: 1 to 50 of 108

1.

A New Hope: Self-Assembling Peptides with Antimicrobial Activity.

Lombardi L, Falanga A, Del Genio V, Galdiero S.

Pharmaceutics. 2019 Apr 4;11(4). pii: E166. doi: 10.3390/pharmaceutics11040166. Review.

2.

Enhancing the Potency of Antimicrobial Peptides through Molecular Engineering and Self-Assembly.

Lombardi L, Shi Y, Falanga A, Galdiero E, de Alteriis E, Franci G, Chourpa I, Azevedo HS, Galdiero S.

Biomacromolecules. 2019 Mar 11;20(3):1362-1374. doi: 10.1021/acs.biomac.8b01740. Epub 2019 Feb 22.

PMID:
30735368
3.

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes⁻4.

Mangoni AA, Guillou C, Vanden Eynde JJ, Hulme C, Jampilek J, Li W, Prokai-Tatrai K, Rautio J, Collina S, Tuccinardi T, Sousa ME, Sabatier JM, Galdiero S, Karaman R, Kokotos G, Torri G, Luque FJ, Vasconcelos MH, Hadjipavlou-Litina D, Siciliano C, Gütschow M, Ragno R, Gomes PAC, Agrofoglio LA, Muñoz-Torrero D.

Molecules. 2018 Dec 31;24(1). pii: E130. doi: 10.3390/molecules24010130.

4.

Polymicrobial antibiofilm activity of the membranotropic peptide gH625 and its analogue.

de Alteriis E, Lombardi L, Falanga A, Napolano M, Galdiero S, Siciliano A, Carotenuto R, Guida M, Galdiero E.

Microb Pathog. 2018 Dec;125:189-195. doi: 10.1016/j.micpath.2018.09.027. Epub 2018 Sep 15.

5.

Enhanced uptake of gH625 by blood brain barrier compared to liver in vivo: characterization of the mechanism by an in vitro model and implications for delivery.

Falanga A, Iachetta G, Lombardi L, Perillo E, Lombardi A, Morelli G, Valiante S, Galdiero S.

Sci Rep. 2018 Sep 14;8(1):13836. doi: 10.1038/s41598-018-32095-w.

6.

Formulation and in vitro evaluation of a siRNA delivery nanosystem decorated with gH625 peptide for triple negative breast cancer theranosis.

Ben Djemaa S, David S, Hervé-Aubert K, Falanga A, Galdiero S, Allard-Vannier E, Chourpa I, Munnier E.

Eur J Pharm Biopharm. 2018 Oct;131:99-108. doi: 10.1016/j.ejpb.2018.07.024. Epub 2018 Jul 29.

PMID:
30063968
7.

Efficiency of gold nanoparticles coated with the antimicrobial peptide indolicidin against biofilm formation and development of Candida spp. clinical isolates.

de Alteriis E, Maselli V, Falanga A, Galdiero S, Di Lella FM, Gesuele R, Guida M, Galdiero E.

Infect Drug Resist. 2018 Jul 3;11:915-925. doi: 10.2147/IDR.S164262. eCollection 2018.

8.

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-3.

Mangoni AA, Tuccinardi T, Collina S, Vanden Eynde JJ, Muñoz-Torrero D, Karaman R, Siciliano C, de Sousa ME, Prokai-Tatrai K, Rautio J, Guillou C, Gütschow M, Galdiero S, Liu H, Agrofoglio LA, Sabatier JM, Hulme C, Kokotos G, You Q, Gomes PAC.

Molecules. 2018 Jun 30;23(7). pii: E1596. doi: 10.3390/molecules23071596. No abstract available.

9.

Peptide chemistry encounters nanomedicine: recent applications and upcoming scenarios in cancer.

Falanga A, Galdiero S.

Future Med Chem. 2018 Aug 1;10(16):1877-1880. doi: 10.4155/fmc-2018-0182. Epub 2018 Jun 20. No abstract available.

10.

Genotoxicity of gold nanoparticles functionalized with indolicidin towards Saccharomyces cerevisiae.

de Alteriis E, Falanga A, Galdiero S, Guida M, Maselli V, Galdiero E.

J Environ Sci (China). 2018 Apr;66:138-145. doi: 10.1016/j.jes.2017.04.034. Epub 2017 May 10.

PMID:
29628080
11.

Metabolomic and oxidative effects of quantum dots-indolicidin on three generations of Daphnia magna.

Falanga A, Mercurio FA, Siciliano A, Lombardi L, Galdiero S, Guida M, Libralato G, Leone M, Galdiero E.

Aquat Toxicol. 2018 May;198:158-164. doi: 10.1016/j.aquatox.2018.03.001. Epub 2018 Mar 8.

PMID:
29547731
12.

Comparison Between Folic Acid and gH625 Peptide-Based Functionalization of Fe3O4 Magnetic Nanoparticles for Enhanced Cell Internalization.

Tudisco C, Cambria MT, Giuffrida AE, Sinatra F, Anfuso CD, Lupo G, Caporarello N, Falanga A, Galdiero S, Oliveri V, Satriano C, Condorelli GG.

Nanoscale Res Lett. 2018 Feb 7;13(1):45. doi: 10.1186/s11671-018-2459-8.

13.

Peptide-Based Drugs and Drug Delivery Systems.

Galdiero S, Gomes PAC.

Molecules. 2017 Dec 8;22(12). pii: E2185. doi: 10.3390/molecules22122185. No abstract available.

14.

Function Oriented Molecular Design: Dendrimers as Novel Antimicrobials.

García-Gallego S, Franci G, Falanga A, Gómez R, Folliero V, Galdiero S, de la Mata FJ, Galdiero M.

Molecules. 2017 Sep 21;22(10). pii: E1581. doi: 10.3390/molecules22101581. Review.

15.

Dimerization in tailoring uptake efficacy of the HSV-1 derived membranotropic peptide gH625.

Falanga A, Valiante S, Galdiero E, Franci G, Scudiero O, Morelli G, Galdiero S.

Sci Rep. 2017 Aug 25;7(1):9434. doi: 10.1038/s41598-017-09001-x.

16.

Cyclic Peptides as Novel Therapeutic Microbicides: Engineering of Human Defensin Mimetics.

Falanga A, Nigro E, De Biasi MG, Daniele A, Morelli G, Galdiero S, Scudiero O.

Molecules. 2017 Jul 20;22(7). pii: E1217. doi: 10.3390/molecules22071217. Review.

17.

Daphnia magna and Xenopus laevis as in vivo models to probe toxicity and uptake of quantum dots functionalized with gH625.

Galdiero E, Falanga A, Siciliano A, Maselli V, Guida M, Carotenuto R, Tussellino M, Lombardi L, Benvenuto G, Galdiero S.

Int J Nanomedicine. 2017 Apr 4;12:2717-2731. doi: 10.2147/IJN.S127226. eCollection 2017.

18.

Synthesis and in vitro evaluation of fluorescent and magnetic nanoparticles functionalized with a cell penetrating peptide for cancer theranosis.

Perillo E, Hervé-Aubert K, Allard-Vannier E, Falanga A, Galdiero S, Chourpa I.

J Colloid Interface Sci. 2017 Aug 1;499:209-217. doi: 10.1016/j.jcis.2017.03.106. Epub 2017 Mar 29.

PMID:
28388503
19.

Antimicrobial peptides at work: interaction of myxinidin and its mutant WMR with lipid bilayers mimicking the P. aeruginosa and E. coli membranes.

Lombardi L, Stellato MI, Oliva R, Falanga A, Galdiero M, Petraccone L, D'Errico G, De Santis A, Galdiero S, Del Vecchio P.

Sci Rep. 2017 Mar 15;7:44425. doi: 10.1038/srep44425.

20.

Multigenerational effects and DNA alterations of QDs-Indolicidin on Daphnia magna.

Maselli V, Siciliano A, Giorgio A, Falanga A, Galdiero S, Guida M, Fulgione D, Galdiero E.

Environ Pollut. 2017 May;224:597-605. doi: 10.1016/j.envpol.2017.02.043. Epub 2017 Feb 24.

PMID:
28242252
21.

Infectivity inhibition by overlapping synthetic peptides derived from the gH/gL heterodimer of herpes simplex virus type 1.

Franci G, Falanga A, Zannella C, Folliero V, Martora F, Galdiero M, Galdiero S, Morelli G, Galdiero M.

J Pept Sci. 2017 Apr;23(4):311-319. doi: 10.1002/psc.2979. Epub 2017 Feb 14.

PMID:
28194842
22.

An integrated study on antimicrobial activity and ecotoxicity of quantum dots and quantum dots coated with the antimicrobial peptide indolicidin.

Galdiero E, Siciliano A, Maselli V, Gesuele R, Guida M, Fulgione D, Galdiero S, Lombardi L, Falanga A.

Int J Nanomedicine. 2016 Aug 26;11:4199-211. doi: 10.2147/IJN.S107752. eCollection 2016.

23.

Marine Antimicrobial Peptides: Nature Provides Templates for the Design of Novel Compounds against Pathogenic Bacteria.

Falanga A, Lombardi L, Franci G, Vitiello M, Iovene MR, Morelli G, Galdiero M, Galdiero S.

Int J Mol Sci. 2016 May 21;17(5). pii: E785. doi: 10.3390/ijms17050785. Review.

24.

Nanocarriers Conjugated with Cell Penetrating Peptides: New Trojan Horses by Modern Ulysses.

Zappavigna S, Misso G, Falanga A, Perillo E, Novellino E, Galdiero M, Grieco P, Caraglia M, Galdiero S.

Curr Pharm Biotechnol. 2016;17(8):700-22. Review.

PMID:
27087493
25.

An ancestral host defence peptide within human β-defensin 3 recapitulates the antibacterial and antiviral activity of the full-length molecule.

Nigro E, Colavita I, Sarnataro D, Scudiero O, Zambrano G, Granata V, Daniele A, Carotenuto A, Galdiero S, Folliero V, Galdiero M, Urbanowicz RA, Ball JK, Salvatore F, Pessi A.

Sci Rep. 2015 Dec 21;5:18450. doi: 10.1038/srep18450.

26.

Liposome armed with herpes virus-derived gH625 peptide to overcome doxorubicin resistance in lung adenocarcinoma cell lines.

Perillo E, Porto S, Falanga A, Zappavigna S, Stiuso P, Tirino V, Desiderio V, Papaccio G, Galdiero M, Giordano A, Galdiero S, Caraglia M.

Oncotarget. 2016 Jan 26;7(4):4077-92. doi: 10.18632/oncotarget.6013.

27.

Membranotropic Cell Penetrating Peptides: The Outstanding Journey.

Falanga A, Galdiero M, Galdiero S.

Int J Mol Sci. 2015 Oct 23;16(10):25323-37. doi: 10.3390/ijms161025323. Review.

28.

Design and activity of a cyclic mini-β-defensin analog: a novel antimicrobial tool.

Scudiero O, Nigro E, Cantisani M, Colavita I, Leone M, Mercurio FA, Galdiero M, Pessi A, Daniele A, Salvatore F, Galdiero S.

Int J Nanomedicine. 2015 Oct 15;10:6523-39. doi: 10.2147/IJN.S89610. eCollection 2015.

29.

Surface decoration with gH625-membranotropic peptides as a method to escape the endo-lysosomal compartment and reduce nanoparticle toxicity.

Guarnieri D, Muscetti O, Falanga A, Fusco S, Belli V, Perillo E, Battista E, Panzetta V, Galdiero S, Netti PA.

Nanotechnology. 2015 Oct 16;26(41):415101. doi: 10.1088/0957-4484/26/41/415101. Epub 2015 Sep 25.

PMID:
26403519
30.

The identification of a novel Sulfolobus islandicus CAMP-like peptide points to archaeal microorganisms as cell factories for the production of antimicrobial molecules.

Notomista E, Falanga A, Fusco S, Pirone L, Zanfardino A, Galdiero S, Varcamonti M, Pedone E, Contursi P.

Microb Cell Fact. 2015 Sep 4;14:126. doi: 10.1186/s12934-015-0302-9.

31.

Silver nanoparticles as potential antibacterial agents.

Franci G, Falanga A, Galdiero S, Palomba L, Rai M, Morelli G, Galdiero M.

Molecules. 2015 May 18;20(5):8856-74. doi: 10.3390/molecules20058856. Review.

32.

Investigating the inclusion properties of aromatic amino acids complexing beta-cyclodextrins in model peptides.

Caso JV, Russo L, Palmieri M, Malgieri G, Galdiero S, Falanga A, Isernia C, Iacovino R.

Amino Acids. 2015 Oct;47(10):2215-27. doi: 10.1007/s00726-015-2003-4. Epub 2015 May 19.

PMID:
25985927
33.

Quantitative and qualitative effect of gH625 on the nanoliposome-mediated delivery of mitoxantrone anticancer drug to HeLa cells.

Perillo E, Allard-Vannier E, Falanga A, Stiuso P, Vitiello MT, Galdiero M, Galdiero S, Chourpa I.

Int J Pharm. 2015 Jul 5;488(1-2):59-66. doi: 10.1016/j.ijpharm.2015.04.039. Epub 2015 Apr 17.

PMID:
25891256
34.

Integrated analysis of the ecotoxicological and genotoxic effects of the antimicrobial peptide melittin on Daphnia magna and Pseudokirchneriella subcapitata.

Galdiero E, Maselli V, Falanga A, Gesuele R, Galdiero S, Fulgione D, Guida M.

Environ Pollut. 2015 Aug;203:145-152. doi: 10.1016/j.envpol.2015.03.046. Epub 2015 Apr 14.

PMID:
25884346
35.

Peptide gH625 enters into neuron and astrocyte cell lines and crosses the blood-brain barrier in rats.

Valiante S, Falanga A, Cigliano L, Iachetta G, Busiello RA, La Marca V, Galdiero M, Lombardi A, Galdiero S.

Int J Nanomedicine. 2015 Mar 10;10:1885-98. doi: 10.2147/IJN.S77734. eCollection 2015.

36.

Antimicrobial peptides as an opportunity against bacterial diseases.

Galdiero S, Falanga A, Berisio R, Grieco P, Morelli G, Galdiero M.

Curr Med Chem. 2015;22(14):1665-77. Review.

PMID:
25760092
37.

Liposomal doxorubicin doubly functionalized with CCK8 and R8 peptide sequences for selective intracellular drug delivery.

Ringhieri P, Diaferia C, Galdiero S, Palumbo R, Morelli G, Accardo A.

J Pept Sci. 2015 May;21(5):415-25. doi: 10.1002/psc.2759. Epub 2015 Mar 6.

PMID:
25754969
38.

Fusion of raft-like lipid bilayers operated by a membranotropic domain of the HSV-type I glycoprotein gH occurs through a cholesterol-dependent mechanism.

Vitiello G, Falanga A, Petruk AA, Merlino A, Fragneto G, Paduano L, Galdiero S, D'Errico G.

Soft Matter. 2015 Apr 21;11(15):3003-16. doi: 10.1039/c4sm02769h.

PMID:
25734956
39.

Elucidation of the interaction mechanism with liposomes of gH625-peptide functionalized dendrimers.

Falanga A, Tarallo R, Carberry T, Galdiero M, Weck M, Galdiero S.

PLoS One. 2014 Nov 25;9(11):e112128. doi: 10.1371/journal.pone.0112128. eCollection 2014.

40.

gH625: a milestone in understanding the many roles of membranotropic peptides.

Galdiero S, Falanga A, Morelli G, Galdiero M.

Biochim Biophys Acta. 2015 Jan;1848(1 Pt A):16-25. doi: 10.1016/j.bbamem.2014.10.006. Epub 2014 Oct 12. Review.

41.

Tumor-activated prodrug (TAP)-conjugated nanoparticles with cleavable domains for safe doxorubicin delivery.

Guarnieri D, Biondi M, Yu H, Belli V, Falanga AP, Cantisani M, Galdiero S, Netti PA.

Biotechnol Bioeng. 2015 Mar;112(3):601-11. doi: 10.1002/bit.25454. Epub 2014 Nov 24.

PMID:
25220931
42.

Structural insights into and activity analysis of the antimicrobial peptide myxinidin.

Cantisani M, Finamore E, Mignogna E, Falanga A, Nicoletti GF, Pedone C, Morelli G, Leone M, Galdiero M, Galdiero S.

Antimicrob Agents Chemother. 2014 Sep;58(9):5280-90. doi: 10.1128/AAC.02395-14. Epub 2014 Jun 23.

43.

Exploitation of viral properties for intracellular delivery.

Galdiero S, Falanga A, Vitiello M, Grieco P, Caraglia M, Morelli G, Galdiero M.

J Pept Sci. 2014 Jul;20(7):468-78. doi: 10.1002/psc.2649. Epub 2014 May 30. Review.

PMID:
24889153
44.

Silver nanoparticles: therapeutical uses, toxicity, and safety issues.

Dos Santos CA, Seckler MM, Ingle AP, Gupta I, Galdiero S, Galdiero M, Gade A, Rai M.

J Pharm Sci. 2014 Jul;103(7):1931-1944. doi: 10.1002/jps.24001. Epub 2014 May 13. Review.

PMID:
24824033
45.

Metal nanoparticles: The protective nanoshield against virus infection.

Rai M, Deshmukh SD, Ingle AP, Gupta IR, Galdiero M, Galdiero S.

Crit Rev Microbiol. 2016;42(1):46-56. doi: 10.3109/1040841X.2013.879849. Epub 2014 Apr 22. Review.

PMID:
24754250
46.

Broad-spectrum bioactivities of silver nanoparticles: the emerging trends and future prospects.

Rai M, Kon K, Ingle A, Duran N, Galdiero S, Galdiero M.

Appl Microbiol Biotechnol. 2014 Mar;98(5):1951-61. doi: 10.1007/s00253-013-5473-x. Epub 2014 Jan 10. Review.

PMID:
24407450
47.

Antiviral activity of mycosynthesized silver nanoparticles against herpes simplex virus and human parainfluenza virus type 3.

Gaikwad S, Ingle A, Gade A, Rai M, Falanga A, Incoronato N, Russo L, Galdiero S, Galdiero M.

Int J Nanomedicine. 2013;8:4303-14. doi: 10.2147/IJN.S50070. Epub 2013 Nov 6.

48.

Conformational modifications of gB from herpes simplex virus type 1 analyzed by synthetic peptides.

Cantisani M, Falanga A, Incoronato N, Russo L, De Simone A, Morelli G, Berisio R, Galdiero M, Galdiero S.

J Med Chem. 2013 Nov 14;56(21):8366-76. doi: 10.1021/jm400771k. Epub 2013 Oct 25.

PMID:
24160917
49.

Peptide-lipid interactions: experiments and applications.

Galdiero S, Falanga A, Cantisani M, Vitiello M, Morelli G, Galdiero M.

Int J Mol Sci. 2013 Sep 12;14(9):18758-89. doi: 10.3390/ijms140918758.

50.

Structure-activity relations of myxinidin, an antibacterial peptide derived from the epidermal mucus of hagfish.

Cantisani M, Leone M, Mignogna E, Kampanaraki K, Falanga A, Morelli G, Galdiero M, Galdiero S.

Antimicrob Agents Chemother. 2013 Nov;57(11):5665-73. doi: 10.1128/AAC.01341-13. Epub 2013 Sep 3.

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