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Items: 23

1.

CarD contributes to diverse gene expression outcomes throughout the genome of Mycobacterium tuberculosis.

Zhu DX, Garner AL, Galburt EA, Stallings CL.

Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13573-13581. doi: 10.1073/pnas.1900176116. Epub 2019 Jun 19.

PMID:
31217290
2.

CarD and RbpA modify the kinetics of initial transcription and slow promoter escape of the Mycobacterium tuberculosis RNA polymerase.

Jensen D, Manzano AR, Rammohan J, Stallings CL, Galburt EA.

Nucleic Acids Res. 2019 Jul 26;47(13):6685-6698. doi: 10.1093/nar/gkz449.

3.

Single-molecule approach for studying RNAP II transcription initiation using magnetic tweezers.

Tomko EJ, Galburt EA.

Methods. 2019 Apr 15;159-160:35-44. doi: 10.1016/j.ymeth.2019.03.010. Epub 2019 Mar 18.

PMID:
30898685
4.

The calculation of transcript flux ratios reveals single regulatory mechanisms capable of activation and repression.

Galburt EA.

Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):E11604-E11613. doi: 10.1073/pnas.1809454115. Epub 2018 Nov 21.

5.

Domains within RbpA Serve Specific Functional Roles That Regulate the Expression of Distinct Mycobacterial Gene Subsets.

Prusa J, Jensen D, Santiago-Collazo G, Pope SS, Garner AL, Miller JJ, Ruiz Manzano A, Galburt EA, Stallings CL.

J Bacteriol. 2018 Jun 11;200(13). pii: e00690-17. doi: 10.1128/JB.00690-17. Print 2018 Jul 1.

6.

TFIIH generates a six-base-pair open complex during RNAP II transcription initiation and start-site scanning.

Tomko EJ, Fishburn J, Hahn S, Galburt EA.

Nat Struct Mol Biol. 2017 Dec;24(12):1139-1145. doi: 10.1038/nsmb.3500. Epub 2017 Nov 6.

7.

Conformational selection and induced fit as a useful framework for molecular motor mechanisms.

Galburt EA, Tomko EJ.

Biophys Chem. 2017 Apr;223:11-16. doi: 10.1016/j.bpc.2017.01.004. Epub 2017 Feb 3. Review.

9.

Effects of Increasing the Affinity of CarD for RNA Polymerase on Mycobacterium tuberculosis Growth, rRNA Transcription, and Virulence.

Garner AL, Rammohan J, Huynh JP, Onder LM, Chen J, Bae B, Jensen D, Weiss LA, Manzano AR, Darst SA, Campbell EA, Nickels BE, Galburt EA, Stallings CL.

J Bacteriol. 2017 Jan 30;199(4). pii: e00698-16. doi: 10.1128/JB.00698-16. Print 2017 Feb 15.

10.

Cooperative stabilization of Mycobacterium tuberculosis rrnAP3 promoter open complexes by RbpA and CarD.

Rammohan J, Ruiz Manzano A, Garner AL, Prusa J, Stallings CL, Galburt EA.

Nucleic Acids Res. 2016 Sep 6;44(15):7304-13. doi: 10.1093/nar/gkw577. Epub 2016 Jun 24.

11.

Mechanisms of backtrack recovery by RNA polymerases I and II.

Lisica A, Engel C, Jahnel M, Roldán É, Galburt EA, Cramer P, Grill SW.

Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):2946-51. doi: 10.1073/pnas.1517011113. Epub 2016 Feb 29.

12.

CarD stabilizes mycobacterial open complexes via a two-tiered kinetic mechanism.

Rammohan J, Ruiz Manzano A, Garner AL, Stallings CL, Galburt EA.

Nucleic Acids Res. 2015 Mar 31;43(6):3272-85. doi: 10.1093/nar/gkv078. Epub 2015 Feb 19.

13.

CarD integrates three functional modules to promote efficient transcription, antibiotic tolerance, and pathogenesis in mycobacteria.

Garner AL, Weiss LA, Manzano AR, Galburt EA, Stallings CL.

Mol Microbiol. 2014 Aug;93(4):682-97. doi: 10.1111/mmi.12681. Epub 2014 Jul 16.

14.

Force-dependent melting of supercoiled DNA at thermophilic temperatures.

Galburt EA, Tomko EJ, Stump WT, Ruiz Manzano A.

Biophys Chem. 2014 Mar-Apr;187-188:23-8. doi: 10.1016/j.bpc.2014.01.001. Epub 2014 Jan 17.

PMID:
24486433
15.

RNA polymerase pushing.

Galburt EA, Parrondo JM, Grill SW.

Biophys Chem. 2011 Aug;157(1-3):43-7. doi: 10.1016/j.bpc.2011.04.009. Epub 2011 Apr 16.

PMID:
21550712
16.

Single molecule transcription elongation.

Galburt EA, Grill SW, Bustamante C.

Methods. 2009 Aug;48(4):323-32. doi: 10.1016/j.ymeth.2009.04.021. Epub 2009 May 6. Review.

17.

The origin of short transcriptional pauses.

Depken M, Galburt EA, Grill SW.

Biophys J. 2009 Mar 18;96(6):2189-93. doi: 10.1016/j.bpj.2008.12.3918.

18.

Backtracking determines the force sensitivity of RNAP II in a factor-dependent manner.

Galburt EA, Grill SW, Wiedmann A, Lubkowska L, Choy J, Nogales E, Kashlev M, Bustamante C.

Nature. 2007 Apr 12;446(7137):820-3. Epub 2007 Mar 14.

PMID:
17361130
19.

Catalytic mechanisms of restriction and homing endonucleases.

Galburt EA, Stoddard BL.

Biochemistry. 2002 Nov 26;41(47):13851-60. Review.

PMID:
12437341
20.

Structure of a tRNA repair enzyme and molecular biology workhorse: T4 polynucleotide kinase.

Galburt EA, Pelletier J, Wilson G, Stoddard BL.

Structure. 2002 Sep;10(9):1249-60.

21.

Conformational changes and cleavage by the homing endonuclease I-PpoI: a critical role for a leucine residue in the active site.

Galburt EA, Chadsey MS, Jurica MS, Chevalier BS, Erho D, Tang W, Monnat RJ Jr, Stoddard BL.

J Mol Biol. 2000 Jul 21;300(4):877-87.

PMID:
10891275
22.

Restriction endonucleases: one of these things is not like the others.

Galburt EA, Stoddard BL.

Nat Struct Biol. 2000 Feb;7(2):89-91.

PMID:
10655603
23.

A novel endonuclease mechanism directly visualized for I-PpoI.

Galburt EA, Chevalier B, Tang W, Jurica MS, Flick KE, Monnat RJ Jr, Stoddard BL.

Nat Struct Biol. 1999 Dec;6(12):1096-9.

PMID:
10581547

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