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Items: 22

1.

High-level semi-synthetic production of the potent antimalarial artemisinin.

Paddon CJ, Westfall PJ, Pitera DJ, Benjamin K, Fisher K, McPhee D, Leavell MD, Tai A, Main A, Eng D, Polichuk DR, Teoh KH, Reed DW, Treynor T, Lenihan J, Fleck M, Bajad S, Dang G, Dengrove D, Diola D, Dorin G, Ellens KW, Fickes S, Galazzo J, Gaucher SP, Geistlinger T, Henry R, Hepp M, Horning T, Iqbal T, Jiang H, Kizer L, Lieu B, Melis D, Moss N, Regentin R, Secrest S, Tsuruta H, Vazquez R, Westblade LF, Xu L, Yu M, Zhang Y, Zhao L, Lievense J, Covello PS, Keasling JD, Reiling KK, Renninger NS, Newman JD.

Nature. 2013 Apr 25;496(7446):528-32. doi: 10.1038/nature12051. Epub 2013 Apr 10.

PMID:
23575629
2.

Potent non-benzoquinone ansamycin heat shock protein 90 inhibitors from genetic engineering of Streptomyces hygroscopicus.

Menzella HG, Tran TT, Carney JR, Lau-Wee J, Galazzo J, Reeves CD, Carreras C, Mukadam S, Eng S, Zhong Z, Timmermans PB, Murli S, Ashley GW.

J Med Chem. 2009 Mar 26;52(6):1518-21. doi: 10.1021/jm900012a.

PMID:
19231864
3.

Cytotoxic hypothemycin analogues from Hypomyces subiculosus.

Wee JL, Sundermann K, Licari P, Galazzo J.

J Nat Prod. 2006 Oct;69(10):1456-9.

PMID:
17067161
4.

Characterization of product capture resin during microbial cultivations.

Frykman S, Tsuruta H, Galazzo J, Licari P.

J Ind Microbiol Biotechnol. 2006 Jun;33(6):445-53. Epub 2006 Feb 11.

PMID:
16474950
5.

Production of 8-demethylgeldanamycin and 4,5-epoxy-8-demethylgeldanamycin from a recombinant strain of Streptomyces hygroscopicus.

Buchanan GO, Regentin R, Piagentini M, Rascher A, McDaniel R, Galazzo JL, Licari PJ.

J Nat Prod. 2005 Apr;68(4):607-10.

PMID:
15844961
6.
7.
8.

A sensitive and robust method for quantification of intracellular short-chain coenzyme A esters.

Shimazu M, Vetcher L, Galazzo JL, Licari P, Santi DV.

Anal Biochem. 2004 May 1;328(1):51-9.

PMID:
15081907
9.

Isolation and characterization of 7-hydroxy-6-demethyl-6-deoxy-erythromycin D, a new erythromycin analogue, from engineered Saccharopolyspora erythraea.

Starks CM, Rodriguez E, Carney JR, Desai RP, Carreras C, McDaniel R, Hutchinson R, Galazzo JL, Licari PJ.

J Antibiot (Tokyo). 2004 Jan;57(1):64-7. No abstract available.

10.

Precursor-directed biosynthesis of novel triketide lactones.

Regentin R, Kennedy J, Wu N, Carney JR, Licari P, Galazzo J, Desai R.

Biotechnol Prog. 2004 Jan-Feb;20(1):122-7.

PMID:
14763833
11.

Combining classical, genetic, and process strategies for improved precursor-directed production of 6-deoxyerythronolide B analogues.

Desai RP, Leaf T, Hu Z, Hutchinson CR, Hong A, Byng G, Galazzo J, Licari P.

Biotechnol Prog. 2004 Jan-Feb;20(1):38-43.

PMID:
14763821
12.

MF-EA-705alpha & MF-EA-705beta, new metabolites from microbial fermentation of a Streptomyces sp.

Qureshi A, Mauger JB, Cano RJ, Galazzo JL, Lee MD.

J Antibiot (Tokyo). 2001 Dec;54(12):1100-3. No abstract available.

13.

Microbial fermentation-derived inhibitors of efflux-pump-mediated drug resistance.

Lee MD, Galazzo JL, Staley AL, Lee JC, Warren MS, Fuernkranz H, Chamberland S, Lomovskaya O, Miller GH.

Farmaco. 2001 Jan-Feb;56(1-2):81-5. Review.

PMID:
11347972
14.

New pacidamycins produced by Streptomyces coeruleorubidus, NRRL 18370.

Fronko RM, Lee JC, Galazzo JG, Chamberland S, Malouin F, Lee MD.

J Antibiot (Tokyo). 2000 Dec;53(12):1405-10. No abstract available.

15.

Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: novel agents for combination therapy.

Lomovskaya O, Warren MS, Lee A, Galazzo J, Fronko R, Lee M, Blais J, Cho D, Chamberland S, Renau T, Leger R, Hecker S, Watkins W, Hoshino K, Ishida H, Lee VJ.

Antimicrob Agents Chemother. 2001 Jan;45(1):105-16.

16.

The production of cephalosporin C by Acremonium chrysogenum is improved by the intracellular expression of a bacterial hemoglobin.

DeModena JA, Gutiérrez S, Velasco J, Fernández FJ, Fachini RA, Galazzo JL, Hughes DE, Martín JF.

Biotechnology (N Y). 1993 Aug;11(8):926-9.

PMID:
7763915
17.

Actinorhodin production by Streptomyces coelicolor and growth of Streptomyces lividans are improved by the expression of a bacterial hemoglobin.

Magnolo SK, Leenutaphong DL, DeModena JA, Curtis JE, Bailey JE, Galazzo JL, Hughes DE.

Biotechnology (N Y). 1991 May;9(5):473-6.

PMID:
1367312
18.
19.

Comparison of intracellular sugar-phosphate levels from 31P nmr spectroscopy of intact cells and cell-free extracts.

Galazzo JL, Shanks JV, Bailey JE.

Biotechnol Bioeng. 1990 May;35(11):1164-8. No abstract available.

PMID:
18592497
20.

Strategies and challenges in metabolic engineering.

Bailey JE, Birnbaum S, Galazzo JL, Khosla C, Shanks JV.

Ann N Y Acad Sci. 1990;589:1-15. No abstract available.

PMID:
2192652
21.
22.

Redirection of cellular metabolism. Analysis and synthesis.

Bailey JE, Axe DD, Doran PM, Galazzo JL, Reardon KF, Seressiotis A, Shanks JV.

Ann N Y Acad Sci. 1987;506:1-23. Review. No abstract available.

PMID:
3324849

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