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Items: 18


mRNA-seq whole transcriptome profiling of fresh frozen versus archived fixed tissues.

Bossel Ben-Moshe N, Gilad S, Perry G, Benjamin S, Balint-Lahat N, Pavlovsky A, Halperin S, Markus B, Yosepovich A, Barshack I, Gal-Yam EN, Domany E, Kaufman B, Dadiani M.

BMC Genomics. 2018 May 30;19(1):419. doi: 10.1186/s12864-018-4761-3.


Evaluation of tolerability and efficacy of incorporating carboplatin in neoadjuvant anthracycline and taxane based therapy in a BRCA1 enriched triple-negative breast cancer cohort.

Sella T, Gal Yam EN, Levanon K, Rotenberg TS, Gadot M, Kuchuk I, Molho RB, Itai A, Modiano TM, Gold R, Kaufman B, Shimon SP.

Breast. 2018 Aug;40:141-146. doi: 10.1016/j.breast.2018.05.007. Epub 2018 May 22.


Tumor Evolution Inferred by Patterns of microRNA Expression through the Course of Disease, Therapy, and Recurrence in Breast Cancer.

Dadiani M, Bossel Ben-Moshe N, Paluch-Shimon S, Perry G, Balint N, Marin I, Pavlovski A, Morzaev D, Kahana-Edwin S, Yosepovich A, Gal-Yam EN, Berger R, Barshack I, Domany E, Kaufman B.

Clin Cancer Res. 2016 Jul 15;22(14):3651-62. doi: 10.1158/1078-0432.CCR-15-2313. Epub 2016 Mar 8.


Activation-Induced Cytidine Deaminase Links Ovulation-Induced Inflammation and Serous Carcinogenesis.

Sapoznik S, Bahar-Shany K, Brand H, Pinto Y, Gabay O, Glick-Saar E, Dor C, Zadok O, Barshack I, Zundelevich A, Gal-Yam EN, Yung Y, Hourvitz A, Korach J, Beiner M, Jacob J, Levanon EY, Barak M, Aviel-Ronen S, Levanon K.

Neoplasia. 2016 Feb;18(2):90-9. doi: 10.1016/j.neo.2015.12.003.


Chromatin-modifying agents reactivate embryonic renal stem/progenitor genes in human adult kidney epithelial cells but abrogate dedifferentiation and stemness.

Omer D, Harari-Steinberg O, Buzhor E, Metsuyanim S, Pleniceanu O, Zundelevich A, Gal-Yam EN, Dekel B.

Cell Reprogram. 2013 Aug;15(4):281-92. doi: 10.1089/cell.2012.0087. Epub 2013 Jul 10.


Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues.

Landan G, Cohen NM, Mukamel Z, Bar A, Molchadsky A, Brosh R, Horn-Saban S, Zalcenstein DA, Goldfinger N, Zundelevich A, Gal-Yam EN, Rotter V, Tanay A.

Nat Genet. 2012 Nov;44(11):1207-14. doi: 10.1038/ng.2442. Epub 2012 Oct 14.


Epigenetic silencing of the tumor suppressor klotho in human breast cancer.

Rubinek T, Shulman M, Israeli S, Bose S, Avraham A, Zundelevich A, Evron E, Gal-Yam EN, Kaufman B, Wolf I.

Breast Cancer Res Treat. 2012 Jun;133(2):649-57. doi: 10.1007/s10549-011-1824-4. Epub 2011 Oct 22.


Mutant p53(R175H) upregulates Twist1 expression and promotes epithelial-mesenchymal transition in immortalized prostate cells.

Kogan-Sakin I, Tabach Y, Buganim Y, Molchadsky A, Solomon H, Madar S, Kamer I, Stambolsky P, Shelly A, Goldfinger N, Valsesia-Wittmann S, Puisieux A, Zundelevich A, Gal-Yam EN, Avivi C, Barshack I, Brait M, Sidransky D, Domany E, Rotter V.

Cell Death Differ. 2011 Feb;18(2):271-81. doi: 10.1038/cdd.2010.94. Epub 2010 Aug 6.


Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line.

Gal-Yam EN, Egger G, Iniguez L, Holster H, Einarsson S, Zhang X, Lin JC, Liang G, Jones PA, Tanay A.

Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12979-84. doi: 10.1073/pnas.0806437105. Epub 2008 Aug 27.


Epigenetic regulation and nucleosome positioning in the human TATA-less IL-1 alpha promoter.

van Rietschoten JG, Gal-Yam EN, Jeong S, Cortez CC, Verweij CL, Jones PA.

Genes Immun. 2008 Oct;9(7):582-90. doi: 10.1038/gene.2008.53. Epub 2008 Jul 10.


LAP2zeta binds BAF and suppresses LAP2beta-mediated transcriptional repression.

Shaklai S, Somech R, Gal-Yam EN, Deshet-Unger N, Moshitch-Moshkovitz S, Hirschberg K, Amariglio N, Simon AJ, Rechavi G.

Eur J Cell Biol. 2008 May;87(5):267-78. doi: 10.1016/j.ejcb.2008.01.014. Epub 2008 Apr 9.


Role of nucleosomal occupancy in the epigenetic silencing of the MLH1 CpG island.

Lin JC, Jeong S, Liang G, Takai D, Fatemi M, Tsai YC, Egger G, Gal-Yam EN, Jones PA.

Cancer Cell. 2007 Nov;12(5):432-44.


Cancer epigenetics: modifications, screening, and therapy.

Gal-Yam EN, Saito Y, Egger G, Jones PA.

Annu Rev Med. 2008;59:267-80. Review.


Enhanced expression of the nuclear envelope LAP2 transcriptional repressors in normal and malignant activated lymphocytes.

Somech R, Gal-Yam EN, Shaklai S, Geller O, Amariglio N, Rechavi G, Simon AJ.

Ann Hematol. 2007 Jun;86(6):393-401. Epub 2007 Mar 16.


Constitutive nucleosome depletion and ordered factor assembly at the GRP78 promoter revealed by single molecule footprinting.

Gal-Yam EN, Jeong S, Tanay A, Egger G, Lee AS, Jones PA.

PLoS Genet. 2006 Sep 22;2(9):e160.


Footprinting of mammalian promoters: use of a CpG DNA methyltransferase revealing nucleosome positions at a single molecule level.

Fatemi M, Pao MM, Jeong S, Gal-Yam EN, Egger G, Weisenberger DJ, Jones PA.

Nucleic Acids Res. 2005 Nov 27;33(20):e176.


The nuclear-envelope protein and transcriptional repressor LAP2beta interacts with HDAC3 at the nuclear periphery, and induces histone H4 deacetylation.

Somech R, Shaklai S, Geller O, Amariglio N, Simon AJ, Rechavi G, Gal-Yam EN.

J Cell Sci. 2005 Sep 1;118(Pt 17):4017-25.


Reduced human germ cell-less (HGCL) expression in azoospermic men with severe germinal cell impairment.

Kleiman SE, Yogev L, Gal-Yam EN, Hauser R, Gamzu R, Botchan A, Paz G, Yavetz H, Maymon BB, Schreiber L, Barzilai S, Amariglio N, Rechavi G, Simon AJ.

J Androl. 2003 Sep-Oct;24(5):670-5.

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