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Items: 1 to 50 of 116

1.

Short-term effects of a 3-week interval training program on heart rate variability in chronic heart failure. A randomised controlled trial.

Besnier F, Labrunée M, Richard L, Faggianelli F, Kerros H, Soukarié L, Bousquet M, Garcia JL, Pathak A, Gales C, Guiraud T, Sénard JM.

Ann Phys Rehabil Med. 2019 Sep;62(5):321-328. doi: 10.1016/j.rehab.2019.06.013. Epub 2019 Jul 25.

PMID:
31352063
2.

Deciphering biased inverse agonism of cangrelor and ticagrelor at P2Y12 receptor.

Garcia C, Maurel-Ribes A, Nauze M, N'Guyen D, Martinez LO, Payrastre B, Sénard JM, Galés C, Pons V.

Cell Mol Life Sci. 2019 Feb;76(3):561-576. doi: 10.1007/s00018-018-2960-3. Epub 2018 Nov 7.

PMID:
30406277
3.

Structural evidence for a new elaborate 3D-organization of the cardiomyocyte lateral membrane in adult mammalian cardiac tissues.

Guilbeau-Frugier C, Cauquil M, Karsenty C, Lairez O, Dambrin C, Payré B, Cassard H, Josse C, Seguelas MH, Allart S, Branchereau M, Heymes C, Mandel F, Delisle MB, Pathak A, Dague E, Sénard JM, Galés C.

Cardiovasc Res. 2019 May 1;115(6):1078-1091. doi: 10.1093/cvr/cvy256.

PMID:
30329023
4.

[Why are new drugs so expensive?]

Le Galès C.

Med Sci (Paris). 2018 Apr;34(4):354-361. doi: 10.1051/medsci/20183404017. Epub 2018 Apr 16. French.

5.

GHSR-D2R heteromerization modulates dopamine signaling through an effect on G protein conformation.

Damian M, Pons V, Renault P, M'Kadmi C, Delort B, Hartmann L, Kaya AI, Louet M, Gagne D, Ben Haj Salah K, Denoyelle S, Ferry G, Boutin JA, Wagner R, Fehrentz JA, Martinez J, Marie J, Floquet N, Galès C, Mary S, Hamm HE, Banères JL.

Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):4501-4506. doi: 10.1073/pnas.1712725115. Epub 2018 Apr 9.

6.

[Evolution, determinants and regulation of drug expenditures in France].

Le Galès C.

Med Sci (Paris). 2018 Jan;34(1):83-86. doi: 10.1051/medsci/20183401018. Epub 2018 Jan 31. French.

7.

G protein stoichiometry dictates biased agonism through distinct receptor-G protein partitioning.

Onfroy L, Galandrin S, Pontier SM, Seguelas MH, N'Guyen D, Sénard JM, Galés C.

Sci Rep. 2017 Aug 11;7(1):7885. doi: 10.1038/s41598-017-07392-5.

8.

Nanoscale structural mapping as a measure of maturation in the murine frontal cortex.

Smolyakov G, Dague E, Roux C, Seguelas MH, Galés C, Senard JM, Arvanitis DN.

Brain Struct Funct. 2018 Jan;223(1):255-265. doi: 10.1007/s00429-017-1486-z. Epub 2017 Aug 4.

PMID:
28779306
9.

Biophysical properties of cardiomyocyte surface explored by multiparametric AFM.

Smolyakov G, Cauquil M, Severac C, Lachaize V, Guilbeau-Frugier C, Sénard JM, Galés C, Dague E.

J Struct Biol. 2017 Apr;198(1):28-37. doi: 10.1016/j.jsb.2017.03.001. Epub 2017 Mar 2.

PMID:
28263874
10.

Health-state utility estimates for health technology assessment: a review of the manufacturers' submissions to the French National Authority for Health.

Hamers FF, Ghabri S, Le Gales C.

Expert Rev Pharmacoecon Outcomes Res. 2017 Oct;17(5):489-494. doi: 10.1080/14737167.2017.1289088. Epub 2017 Feb 8.

PMID:
28133977
11.

The protective effects of zinc in experimental gentamicin induced acute renal failure in rats.

Teslariu O, Pasca AS, Mititelu-Tartau L, Schiriac CE, Gales C, Saftencu PM, Nechifor M.

J Physiol Pharmacol. 2016 Oct;67(5):751-757.

12.

Partial Agonist and Biased Signaling Properties of the Synthetic Enantiomers J113863/UCB35625 at Chemokine Receptors CCR2 and CCR5.

Corbisier J, Huszagh A, Galés C, Parmentier M, Springael JY.

J Biol Chem. 2017 Jan 13;292(2):575-584. doi: 10.1074/jbc.M116.757559. Epub 2016 Nov 28.

13.

Signaling Properties of Chemerin Receptors CMKLR1, GPR1 and CCRL2.

De Henau O, Degroot GN, Imbault V, Robert V, De Poorter C, Mcheik S, Galés C, Parmentier M, Springael JY.

PLoS One. 2016 Oct 7;11(10):e0164179. doi: 10.1371/journal.pone.0164179. eCollection 2016.

14.

Cardioprotective Angiotensin-(1-7) Peptide Acts as a Natural-Biased Ligand at the Angiotensin II Type 1 Receptor.

Galandrin S, Denis C, Boularan C, Marie J, M'Kadmi C, Pilette C, Dubroca C, Nicaise Y, Seguelas MH, N'Guyen D, Banères JL, Pathak A, Sénard JM, Galés C.

Hypertension. 2016 Dec;68(6):1365-1374. Epub 2016 Oct 3.

PMID:
27698068
15.

Changes in Some Divalent Cations Concentrations In An Experimental Rat Model of Gentamicin-Induced Acute Renal Failure.

Mititelu-Tarţău L, Teslariu O, Galeş C, Nechifor M.

Rev Med Chir Soc Med Nat Iasi. 2016 Oct-Dec;120(4):947-52.

PMID:
30141892
16.

Exercise training-induced modification in autonomic nervous system: An update for cardiac patients.

Besnier F, Labrunée M, Pathak A, Pavy-Le Traon A, Galès C, Sénard JM, Guiraud T.

Ann Phys Rehabil Med. 2017 Jan;60(1):27-35. doi: 10.1016/j.rehab.2016.07.002. Epub 2016 Aug 16. Review.

17.

Glycosylation-Dependent IFN-γR Partitioning in Lipid and Actin Nanodomains Is Critical for JAK Activation.

Blouin CM, Hamon Y, Gonnord P, Boularan C, Kagan J, Viaris de Lesegno C, Ruez R, Mailfert S, Bertaux N, Loew D, Wunder C, Johannes L, Vogt G, Contreras FX, Marguet D, Casanova JL, Galès C, He HT, Lamaze C.

Cell. 2016 Aug 11;166(4):920-934. doi: 10.1016/j.cell.2016.07.003. Epub 2016 Aug 4.

18.

The family accompaniment of persons with dementia seen through the lens of the capability approach.

Le Galès C, Bungener M.

Dementia (London). 2019 Jan;18(1):55-79. doi: 10.1177/1471301216657476. Epub 2016 Jul 7.

PMID:
27390172
19.

Delineating biased ligand efficacy at 7TM receptors from an experimental perspective.

Galandrin S, Onfroy L, Poirot MC, Sénard JM, Galés C.

Int J Biochem Cell Biol. 2016 Aug;77(Pt B):251-63. doi: 10.1016/j.biocel.2016.04.009. Epub 2016 Apr 21. Review.

PMID:
27107932
20.

Analysis of Arrestin Recruitment to Chemokine Receptors by Bioluminescence Resonance Energy Transfer.

Bonneterre J, Montpas N, Boularan C, Galés C, Heveker N.

Methods Enzymol. 2016;570:131-53. doi: 10.1016/bs.mie.2015.09.003. Epub 2015 Nov 29.

PMID:
26921945
21.

Capability deprivation of people with Alzheimer's disease: An empirical analysis using a national survey.

Tellez J, Krishnakumar J, Bungener M, Le Galès C.

Soc Sci Med. 2016 Feb;151:56-68. doi: 10.1016/j.socscimed.2015.12.032. Epub 2015 Dec 23.

PMID:
26773293
22.

The experimental power of FR900359 to study Gq-regulated biological processes.

Schrage R, Schmitz AL, Gaffal E, Annala S, Kehraus S, Wenzel D, Büllesbach KM, Bald T, Inoue A, Shinjo Y, Galandrin S, Shridhar N, Hesse M, Grundmann M, Merten N, Charpentier TH, Martz M, Butcher AJ, Slodczyk T, Armando S, Effern M, Namkung Y, Jenkins L, Horn V, Stößel A, Dargatz H, Tietze D, Imhof D, Galés C, Drewke C, Müller CE, Hölzel M, Milligan G, Tobin AB, Gomeza J, Dohlman HG, Sondek J, Harden TK, Bouvier M, Laporte SA, Aoki J, Fleischmann BK, Mohr K, König GM, Tüting T, Kostenis E.

Nat Commun. 2015 Dec 14;6:10156. doi: 10.1038/ncomms10156.

23.

Cardiac cAMP: production, hydrolysis, modulation and detection.

Boularan C, Gales C.

Front Pharmacol. 2015 Oct 1;6:203. doi: 10.3389/fphar.2015.00203. eCollection 2015. Review.

24.

Agonism, Antagonism, and Inverse Agonism Bias at the Ghrelin Receptor Signaling.

M'Kadmi C, Leyris JP, Onfroy L, Galés C, Saulière A, Gagne D, Damian M, Mary S, Maingot M, Denoyelle S, Verdié P, Fehrentz JA, Martinez J, Banères JL, Marie J.

J Biol Chem. 2015 Nov 6;290(45):27021-39. doi: 10.1074/jbc.M115.659250. Epub 2015 Sep 11.

25.

Mapping HA-tagged protein at the surface of living cells by atomic force microscopy.

Formosa C, Lachaize V, Galés C, Rols MP, Martin-Yken H, François JM, Duval RE, Dague E.

J Mol Recognit. 2015 Jan;28(1):1-9. doi: 10.1002/jmr.2407.

PMID:
26046654
26.

Dual agonist occupancy of AT1-R-α2C-AR heterodimers results in atypical Gs-PKA signaling.

Bellot M, Galandrin S, Boularan C, Matthies HJ, Despas F, Denis C, Javitch J, Mazères S, Sanni SJ, Pons V, Seguelas MH, Hansen JL, Pathak A, Galli A, Sénard JM, Galés C.

Nat Chem Biol. 2015 Apr;11(4):271-9. doi: 10.1038/nchembio.1766. Epub 2015 Feb 23.

27.

An essential role for RGS protein/Gαi2 interactions in B lymphocyte-directed cell migration and trafficking.

Hwang IY, Park C, Harrison K, Boularan C, Galés C, Kehrl JH.

J Immunol. 2015 Mar 1;194(5):2128-39. doi: 10.4049/jimmunol.1401952. Epub 2015 Jan 23.

28.

Biased signaling at chemokine receptors.

Corbisier J, Galès C, Huszagh A, Parmentier M, Springael JY.

J Biol Chem. 2015 Apr 10;290(15):9542-54. doi: 10.1074/jbc.M114.596098. Epub 2015 Jan 22.

29.

Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor:Gq complex.

Damian M, Mary S, Maingot M, M'Kadmi C, Gagne D, Leyris JP, Denoyelle S, Gaibelet G, Gavara L, Garcia de Souza Costa M, Perahia D, Trinquet E, Mouillac B, Galandrin S, Galès C, Fehrentz JA, Floquet N, Martinez J, Marie J, Banères JL.

Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):1601-6. doi: 10.1073/pnas.1414618112. Epub 2015 Jan 20.

30.

Differential β₂-adrenergic receptor expression defines the phenotype of non-tumorigenic and malignant human breast cell lines.

Gargiulo L, Copsel S, Rivero EM, Galés C, Sénard JM, Lüthy IA, Davio C, Bruzzone A.

Oncotarget. 2014 Oct 30;5(20):10058-69.

31.

Protective effect of magnesium and metformin on endometrium and ovary in experimental diabetes mellitus.

Gales C, Zamfir C, Radulescu D, Stoica B, Nechifor M.

Magnes Res. 2014 Apr-Jun;27(2):69-76. doi: 10.1684/mrh.2014.0363.

32.

A cell-permeable inhibitor to trap Gαq proteins in the empty pocket conformation.

Schmitz AL, Schrage R, Gaffal E, Charpentier TH, Wiest J, Hiltensperger G, Morschel J, Hennen S, Häußler D, Horn V, Wenzel D, Grundmann M, Büllesbach KM, Schröder R, Brewitz HH, Schmidt J, Gomeza J, Galés C, Fleischmann BK, Tüting T, Imhof D, Tietze D, Gütschow M, Holzgrabe U, Sondek J, Harden TK, Mohr K, Kostenis E.

Chem Biol. 2014 Jul 17;21(7):890-902. doi: 10.1016/j.chembiol.2014.06.003.

33.

Atomic force and electron microscopic-based study of sarcolemmal surface of living cardiomyocytes unveils unexpected mitochondrial shift in heart failure.

Dague E, Genet G, Lachaize V, Guilbeau-Frugier C, Fauconnier J, Mias C, Payré B, Chopinet L, Alsteens D, Kasas S, Severac C, Thireau J, Heymes C, Honton B, Lacampagne A, Pathak A, Sénard JM, Galés C.

J Mol Cell Cardiol. 2014 Sep;74:162-72. doi: 10.1016/j.yjmcc.2014.05.006. Epub 2014 May 17.

PMID:
24839910
34.

The effect of pioglitazone on non-pregnant female genital tract in experimental diabetes mellitus.

Galeş C, Zamfir C, Stoica B, Nechifor M.

Rev Med Chir Soc Med Nat Iasi. 2013 Oct-Dec;117(4):954-8.

PMID:
24502075
35.

The influence of oral steroidal contraceptives on magnesium concentration in breast milk.

Urzica D, Gales C, Zamfir C, Nechifor M.

Magnes Res. 2013 Oct-Dec;26(4):188-91. doi: 10.1684/mrh.2014.0353.

36.

Dosage-dependent regulation of cell proliferation and adhesion through dual β2-adrenergic receptor/cAMP signals.

Bruzzone A, Saulière A, Finana F, Sénard JM, Lüthy I, Galés C.

FASEB J. 2014 Mar;28(3):1342-54. doi: 10.1096/fj.13-239285. Epub 2013 Dec 5.

PMID:
24308976
37.

Cardiac fibroblasts regulate sympathetic nerve sprouting and neurocardiac synapse stability.

Mias C, Coatrieux C, Denis C, Genet G, Seguelas MH, Laplace N, Rouzaud-Laborde C, Calise D, Parini A, Cussac D, Pathak A, Sénard JM, Galés C.

PLoS One. 2013 Nov 14;8(11):e79068. doi: 10.1371/journal.pone.0079068. eCollection 2013.

38.

Role of the ubiquitin-proteasome system in the regulation of P2Y13 receptor expression: impact on hepatic HDL uptake.

Pons V, Serhan N, Gayral S, Malaval C, Nauze M, Malet N, Laffargue M, Galés C, Martinez LO.

Cell Mol Life Sci. 2014 May;71(9):1775-88. doi: 10.1007/s00018-013-1471-5. Epub 2013 Sep 13.

PMID:
24030815
39.

High-intensity interval exercise improves vagal tone and decreases arrhythmias in chronic heart failure.

Guiraud T, Labrunee M, Gaucher-Cazalis K, Despas F, Meyer P, Bosquet L, Gales C, Vaccaro A, Bousquet M, Galinier M, Sénard JM, Pathak A.

Med Sci Sports Exerc. 2013 Oct;45(10):1861-7. doi: 10.1249/MSS.0b013e3182967559.

PMID:
23591293
40.

Full and partial agonists of thromboxane prostanoid receptor unveil fine tuning of receptor superactive conformation and G protein activation.

Capra V, Busnelli M, Perenna A, Ambrosio M, Accomazzo MR, Galés C, Chini B, Rovati GE.

PLoS One. 2013;8(3):e60475. doi: 10.1371/journal.pone.0060475. Epub 2013 Mar 28.

41.

[Adult cardiomyocytes wake up: a big step towards cardiac regeneration].

Mias C, Galés C.

Med Sci (Paris). 2013 Mar;29(3):237-9. doi: 10.1051/medsci/2013293002. Epub 2013 Mar 27. French. No abstract available.

42.

Functional enhancement of AT1R potency in the presence of the TPαR is revealed by a comprehensive 7TM receptor co-expression screen.

Hansen JT, Lyngsø C, Speerschneider T, Hansen PB, Galés C, Weiner DM, Sheikh SP, Burstein ES, Hansen JL.

PLoS One. 2013;8(3):e58890. doi: 10.1371/journal.pone.0058890. Epub 2013 Mar 14.

43.

[Adult resident cardiomyocytes wake up: new axis for cardiac tissue regeneration].

Mias C, Genet G, Pathak A, Sénard JM, Galés C.

Med Sci (Paris). 2012 Dec;28(12):1103-9. doi: 10.1051/medsci/20122812021. Epub 2012 Dec 21. Review. French.

44.

Specific interactions between Epac1, β-arrestin2 and PDE4D5 regulate β-adrenergic receptor subtype differential effects on cardiac hypertrophic signaling.

Berthouze-Duquesnes M, Lucas A, Saulière A, Sin YY, Laurent AC, Galés C, Baillie G, Lezoualc'h F.

Cell Signal. 2013 Apr;25(4):970-80. doi: 10.1016/j.cellsig.2012.12.007. Epub 2012 Dec 22.

PMID:
23266473
45.

Specific roles of G(i) protein family members revealed by dissecting SST5 coupling in human pituitary cells.

Peverelli E, Busnelli M, Vitali E, Giardino E, Galés C, Lania AG, Beck-Peccoz P, Chini B, Mantovani G, Spada A.

J Cell Sci. 2013 Jan 15;126(Pt 2):638-44. doi: 10.1242/jcs.116434. Epub 2012 Nov 23.

46.

[G-protein-coupled receptors plasticity and signalling].

Galés C.

Med Sci (Paris). 2012 Oct;28(10):883-5. doi: 10.1051/medsci/20122810018. Epub 2012 Oct 12. Review. French.

47.

[Cardiotoxicity of chemotherapies].

Castel M, Despas F, Modesto A, Gales C, Honton B, Galinier M, Senard JM, Pathak A.

Presse Med. 2013 Jan;42(1):26-39. doi: 10.1016/j.lpm.2012.04.014. Epub 2012 Jun 21. Review. French.

PMID:
22727981
48.

Deciphering biased-agonism complexity reveals a new active AT1 receptor entity.

Saulière A, Bellot M, Paris H, Denis C, Finana F, Hansen JT, Altié MF, Seguelas MH, Pathak A, Hansen JL, Sénard JM, Galés C.

Nat Chem Biol. 2012 Jul;8(7):622-30. doi: 10.1038/nchembio.961. Epub 2012 May 27.

PMID:
22634635
49.

Ephrin-B1 is a novel specific component of the lateral membrane of the cardiomyocyte and is essential for the stability of cardiac tissue architecture cohesion.

Genet G, Guilbeau-Frugier C, Honton B, Dague E, Schneider MD, Coatrieux C, Calise D, Cardin C, Nieto C, Payré B, Dubroca C, Marck P, Heymes C, Dubrac A, Arvanitis D, Despas F, Altié MF, Seguelas MH, Delisle MB, Davy A, Sénard JM, Pathak A, Galés C.

Circ Res. 2012 Mar 2;110(5):688-700. doi: 10.1161/CIRCRESAHA.111.262451. Epub 2012 Feb 2.

50.

Pharmacological agents that affect sperm motility.

Antohi E, Gales C, Nechifor M.

Rev Med Chir Soc Med Nat Iasi. 2011 Oct-Dec;115(4):1183-8.

PMID:
22276467

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