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Multicenter derivation and validation of an early warning score for acute respiratory failure or death in the hospital.

Dziadzko MA, Novotny PJ, Sloan J, Gajic O, Herasevich V, Mirhaji P, Wu Y, Gong MN.

Crit Care. 2018 Oct 30;22(1):286. doi: 10.1186/s13054-018-2194-7.


Respiratory failure in the hematopoietic stem cell transplant recipient.

Wieruszewski PM, Herasevich S, Gajic O, Yadav H.

World J Crit Care Med. 2018 Oct 16;7(5):62-72. doi: 10.5492/wjccm.v7.i5.62. eCollection 2018 Oct 16. Review.


Feasibility of an International Remote Simulation Training Program in Critical Care Delivery: A Pilot Study.

Shao M, Kashyap R, Niven A, Barwise A, Garcia-Arguello L, Suzuki R, Hulyalkar M, Gajic O, Dong Y.

Mayo Clin Proc Innov Qual Outcomes. 2018 Jul 31;2(3):229-233. doi: 10.1016/j.mayocpiqo.2018.06.008. eCollection 2018 Sep.


Risk Factors for Persistent Cognitive Impairment After Critical Illness, Nested Case-Control Study.

Sakusic A, Gajic O, Singh TD, O'Horo JC, Jenkins G, Wilson GA, Petersen R, Fryer JD, Kashyap R, Rabinstein AA.

Crit Care Med. 2018 Sep 14. doi: 10.1097/CCM.0000000000003395. [Epub ahead of print]


When to incorporate point-of-care ultrasound (POCUS) into the initial assessment of acutely ill patients: a pilot crossover study to compare 2 POCUS-assisted simulation protocols.

Bennett CE, Samavedam S, Jayaprakash N, Kogan A, Gajic O, Sekiguchi H.

Cardiovasc Ultrasound. 2018 Sep 11;16(1):14. doi: 10.1186/s12947-018-0132-0.


Differences in Code Status and End-of-Life Decision Making in Patients With Limited English Proficiency in the Intensive Care Unit.

Barwise A, Jaramillo C, Novotny P, Wieland ML, Thongprayoon C, Gajic O, Wilson ME.

Mayo Clin Proc. 2018 Sep;93(9):1271-1281. doi: 10.1016/j.mayocp.2018.04.021. Epub 2018 Aug 9.


Plasma sRAGE is independently associated with increased mortality in ARDS: a meta-analysis of individual patient data.

Jabaudon M, Blondonnet R, Pereira B, Cartin-Ceba R, Lichtenstern C, Mauri T, Determann RM, Drabek T, Hubmayr RD, Gajic O, Uhle F, Coppadoro A, Pesenti A, Schultz MJ, Ranieri MV, Brodska H, Mrozek S, Sapin V, Matthay MA, Constantin JM, Calfee CS.

Intensive Care Med. 2018 Sep;44(9):1388-1399. doi: 10.1007/s00134-018-5327-1. Epub 2018 Jul 26.


Outcomes of critical illness: what is meaningful?

Gajic O, Ahmad SR, Wilson ME, Kaufman DA.

Curr Opin Crit Care. 2018 Oct;24(5):394-400. doi: 10.1097/MCC.0000000000000530.


Features of Adult Hyperammonemia Not Due to Liver Failure in the ICU.

Sakusic A, Sabov M, McCambridge AJ, Rabinstein AA, Singh TD, Mukesh K, Kashani KB, Cook D, Gajic O.

Crit Care Med. 2018 Sep;46(9):e897-e903. doi: 10.1097/CCM.0000000000003278.


Evolution of Validated Biomarkers and Intraoperative Parameters in the Development of Postoperative ARDS.

Yadav H, Bartley A, Keating S, Meade LA, Norris PJ, Carter RE, Gajic O, Kor DJ.

Respir Care. 2018 Nov;63(11):1331-1340. doi: 10.4187/respcare.06103. Epub 2018 Jun 19.


Validation of the sarcopenia index to assess muscle mass in the critically ill: A novel application of kidney function markers.

Barreto EF, Poyant JO, Coville HH, Dierkhising RA, Kennedy CC, Gajic O, Nystrom EM, Takahashi N, Moynagh MR, Kashani KB.

Clin Nutr. 2018 Jun 8. pii: S0261-5614(18)30218-8. doi: 10.1016/j.clnu.2018.05.031. [Epub ahead of print]


Evaluation of TEAM dynamics before and after remote simulation training utilizing CERTAIN platform.

Pennington KM, Dong Y, Coville HH, Wang B, Gajic O, Kelm DJ.

Med Educ Online. 2018 Dec;23(1):1485431. doi: 10.1080/10872981.2018.1485431.


Early Intravascular Events Are Associated with Development of Acute Respiratory Distress Syndrome. A Substudy of the LIPS-A Clinical Trial.

Abdulnour RE, Gunderson T, Barkas I, Timmons JY, Barnig C, Gong M, Kor DJ, Gajic O, Talmor D, Carter RE, Levy BD.

Am J Respir Crit Care Med. 2018 Jun 15;197(12):1575-1585. doi: 10.1164/rccm.201712-2530OC.


Prompting with electronic checklist improves clinician performance in medical emergencies: a high-fidelity simulation study.

Sevilla-Berrios R, O'Horo JC, Schmickl CN, Erdogan A, Chen X, Garcia Arguello LY, Dong Y, Kilickaya O, Pickering B, Kashyap R, Gajic O.

Int J Emerg Med. 2018 Apr 27;11(1):26. doi: 10.1186/s12245-018-0185-8.


Seeking out SARI: an automated search of electronic health records.

O'Horo JC, Dziadzko M, Sakusic A, Ali R, Sohail MR, Kor DJ, Gajic O.

Epidemiol Infect. 2018 Jun;146(8):1065-1069. doi: 10.1017/S0950268818000699. Epub 2018 Apr 18.


Fiberoptic-Guided Use of an Airway Exchange Catheter During Exchange of a Kinked King LTS-D Laryngeal Tube for an Endotracheal Tube: A Case Report.

Kelm DJ, Zhu X, Diedrich DA, Ritter MJ, Gajic O.

A A Pract. 2018 Aug 15;11(4):100-102. doi: 10.1213/XAA.0000000000000753.


Trends in Use of Midodrine in the ICU: A Single-Center Retrospective Case Series.

Rizvi MS, Trivedi V, Nasim F, Lin E, Kashyap R, Andrijasevic N, Gajic O.

Crit Care Med. 2018 Jul;46(7):e628-e633. doi: 10.1097/CCM.0000000000003121.


Predictive Value of the Sequential Organ Failure Assessment Score for Mortality in a Contemporary Cardiac Intensive Care Unit Population.

Jentzer JC, Bennett C, Wiley BM, Murphree DH, Keegan MT, Gajic O, Wright RS, Barsness GW.

J Am Heart Assoc. 2018 Mar 10;7(6). pii: e008169. doi: 10.1161/JAHA.117.008169.


The Incremental Burden of Acute Respiratory Distress Syndrome: Long-term Follow-up of a Population-Based Nested Case-Control Study.

Biehl M, Ahmed A, Kashyap R, Barwise A, Gajic O.

Mayo Clin Proc. 2018 Apr;93(4):445-452. doi: 10.1016/j.mayocp.2017.11.025. Epub 2018 Mar 1.


Noninvasive Ventilation in Patients With Do-Not-Intubate and Comfort-Measures-Only Orders: A Systematic Review and Meta-Analysis.

Wilson ME, Majzoub AM, Dobler CC, Curtis JR, Nayfeh T, Thorsteinsdottir B, Barwise AK, Tilburt JC, Gajic O, Montori VM, Murad MH.

Crit Care Med. 2018 Aug;46(8):1209-1216. doi: 10.1097/CCM.0000000000003082.


Interaction between peri-operative blood transfusion, tidal volume, airway pressure and postoperative ARDS: an individual patient data meta-analysis.

Serpa Neto A, Juffermans NP, Hemmes SNT, Barbas CSV, Beiderlinden M, Biehl M, Fernandez-Bustamante A, Futier E, Gajic O, Jaber S, Kozian A, Licker M, Lin WQ, Memtsoudis SG, Miranda DR, Moine P, Paparella D, Ranieri M, Scavonetto F, Schilling T, Selmo G, Severgnini P, Sprung J, Sundar S, Talmor D, Treschan T, Unzueta C, Weingarten TN, Wolthuis EK, Wrigge H, de Abreu MG, Pelosi P, Schultz MJ; PROVE Network Investigators.

Ann Transl Med. 2018 Jan;6(2):23. doi: 10.21037/atm.2018.01.16.


Potentially Modifiable Risk Factors for Long-Term Cognitive Impairment After Critical Illness: A Systematic Review.

Sakusic A, O'Horo JC, Dziadzko M, Volha D, Ali R, Singh TD, Kashyap R, Farrell AM, Fryer JD, Petersen R, Gajic O, Rabinstein AA.

Mayo Clin Proc. 2018 Jan;93(1):68-82. doi: 10.1016/j.mayocp.2017.11.005. Review.


A qualitative exploration of the discharge process and factors predisposing to readmissions to the intensive care unit.

Ofoma UR, Dong Y, Gajic O, Pickering BW.

BMC Health Serv Res. 2018 Jan 5;18(1):6. doi: 10.1186/s12913-017-2821-z.


Reliability and Validity of the Checklist for Early Recognition and Treatment of Acute Illness and Injury as a Charting Tool in the Medical Intensive Care Unit.

Kogan A, Pennington KM, Vallabhajosyula S, Dziadzko M, Bennett CE, Jensen JB, Gajic O, O'Horo JC.

Indian J Crit Care Med. 2017 Nov;21(11):746-750. doi: 10.4103/ijccm.IJCCM_209_17.


Long-Term Return to Functional Baseline After Mechanical Ventilation in the ICU.

Wilson ME, Barwise A, Heise KJ, Loftsgard TO, Dziadzko M, Cheville A, Majzoub A, Novotny PJ, Gajic O, Biehl M.

Crit Care Med. 2018 Apr;46(4):562-569. doi: 10.1097/CCM.0000000000002927.


Central venous pressure and ultrasonographic measurement correlation and their associations with intradialytic adverse events in hospitalized patients: A prospective observational study.

Sekiguchi H, Seaburg LA, Suzuki J, Astorne WJ, Patel AS, Keller AS, Gajic O, Kashani KB.

J Crit Care. 2018 Apr;44:168-174. doi: 10.1016/j.jcrc.2017.10.039. Epub 2017 Oct 29.


Lung Recruitment Maneuvers for Adult Patients with Acute Respiratory Distress Syndrome. A Systematic Review and Meta-Analysis.

Goligher EC, Hodgson CL, Adhikari NKJ, Meade MO, Wunsch H, Uleryk E, Gajic O, Amato MPB, Ferguson ND, Rubenfeld GD, Fan E.

Ann Am Thorac Soc. 2017 Oct;14(Supplement_4):S304-S311. doi: 10.1513/AnnalsATS.201704-340OT. Review.


High-Frequency Oscillation for Adult Patients with Acute Respiratory Distress Syndrome. A Systematic Review and Meta-Analysis.

Goligher EC, Munshi L, Adhikari NKJ, Meade MO, Hodgson CL, Wunsch H, Uleryk E, Gajic O, Amato MPB, Ferguson ND, Rubenfeld GD, Fan E.

Ann Am Thorac Soc. 2017 Oct;14(Supplement_4):S289-S296. doi: 10.1513/AnnalsATS.201704-341OT. Review.


Prognostic impact of isolated right ventricular dysfunction in sepsis and septic shock: an 8-year historical cohort study.

Vallabhajosyula S, Kumar M, Pandompatam G, Sakhuja A, Kashyap R, Kashani K, Gajic O, Geske JB, Jentzer JC.

Ann Intensive Care. 2017 Sep 7;7(1):94. doi: 10.1186/s13613-017-0319-9.


Timing of Intubation in Acute Respiratory Failure Associated With Sepsis: A Mixed Methods Study.

Bauer PR, Kumbamu A, Wilson ME, Pannu JK, Egginton JS, Kashyap R, Gajic O.

Mayo Clin Proc. 2017 Oct;92(10):1502-1510. doi: 10.1016/j.mayocp.2017.07.001. Epub 2017 Sep 1.


Risk factors and outcomes of critically ill patients with acute brain failure: A novel end point.

Singh TD, O'Horo JC, Gajic O, Sakusic A, Day CN, Mandrekar J, Kashyap R, Reddy DRS, Rabinstein AA.

J Crit Care. 2018 Feb;43:42-47. doi: 10.1016/j.jcrc.2017.08.028. Epub 2017 Aug 18.


Elevated modified shock index in early sepsis is associated with myocardial dysfunction and mortality.

Jayaprakash N, Gajic O, Frank RD, Smischney N.

J Crit Care. 2018 Feb;43:30-35. doi: 10.1016/j.jcrc.2017.08.019. Epub 2017 Aug 12.


Acute psychological trauma in the critically ill: Patient and family perspectives.

Dziadzko V, Dziadzko MA, Johnson MM, Gajic O, Karnatovskaia LV.

Gen Hosp Psychiatry. 2017 Jul;47:68-74. doi: 10.1016/j.genhosppsych.2017.04.009. Epub 2017 Apr 27.


Quantifying the Effects of Prior Acetyl-Salicylic Acid on Sepsis-Related Deaths: An Individual Patient Data Meta-Analysis Using Propensity Matching.

Trauer J, Muhi S, McBryde ES, Al Harbi SA, Arabi YM, Boyle AJ, Cartin-Ceba R, Chen W, Chen YT, Falcone M, Gajic O, Godsell J, Gong MN, Kor D, Lösche W, McAuley DF, O'Neal HR Jr, Osthoff M, Otto GP, Sossdorf M, Tsai MJ, Valerio-Rojas JC, van der Poll T, Violi F, Ware L, Widmer AF, Wiewel MA, Winning J, Eisen DP.

Crit Care Med. 2017 Nov;45(11):1871-1879. doi: 10.1097/CCM.0000000000002654.


New-Onset Heart Failure and Mortality in Hospital Survivors of Sepsis-Related Left Ventricular Dysfunction.

Vallabhajosyula S, Jentzer JC, Geske JB, Kumar M, Sakhuja A, Singhal A, Poterucha JT, Kashani K, Murphy JG, Gajic O, Kashyap R.

Shock. 2018 Feb;49(2):144-149. doi: 10.1097/SHK.0000000000000952.


Association between timing of intubation and outcome in critically ill patients: A secondary analysis of the ICON audit.

Bauer PR, Gajic O, Nanchal R, Kashyap R, Martin-Loeches I, Sakr Y, Jakob SM, François B, Wittebole X, Wunderink RG, Vincent JL; ICON Investigators (Supplemental Appendix 1).

J Crit Care. 2017 Dec;42:1-5. doi: 10.1016/j.jcrc.2017.06.010. Epub 2017 Jun 16.


No increase in the incidence of acute kidney injury in a population-based annual temporal trends epidemiology study.

Kashani K, Shao M, Li G, Williams AW, Rule AD, Kremers WK, Malinchoc M, Gajic O, Lieske JC.

Kidney Int. 2017 Sep;92(3):721-728. doi: 10.1016/j.kint.2017.03.020. Epub 2017 May 18.


The authors reply.

Soto GJ, Kor DJ, Park PK, Hou PC, Kaufman DA, Kim M, Yadav H, Teman N, Hsu M, Shvilkina T, Grewal Y, De Aguirre M, Gunda S, Gajic O, Gong MN.

Crit Care Med. 2017 Jun;45(6):e625-e626. doi: 10.1097/CCM.0000000000002445. No abstract available.


Learning Health Care System: Pragmatic Comparison of Crystalloid Choice in a Medical Intensive Care Unit.

Cubro H, Kashani K, Gajic O.

Am J Respir Crit Care Med. 2017 May 15;195(10):1287-1289. doi: 10.1164/rccm.201610-2093ED. No abstract available.


Differentiating pulmonary transfusion reactions using recipient and transfusion factors.

Roubinian NH, Looney MR, Keating S, Kor DJ, Lowell CA, Gajic O, Hubmayr R, Gropper M, Koenigsberg M, Wilson GA, A Matthay M, Toy P, Murphy EL; TRALI Study Group.

Transfusion. 2017 Jul;57(7):1684-1690. doi: 10.1111/trf.14118. Epub 2017 May 3.


An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with Acute Respiratory Distress Syndrome.

Fan E, Del Sorbo L, Goligher EC, Hodgson CL, Munshi L, Walkey AJ, Adhikari NKJ, Amato MBP, Branson R, Brower RG, Ferguson ND, Gajic O, Gattinoni L, Hess D, Mancebo J, Meade MO, McAuley DF, Pesenti A, Ranieri VM, Rubenfeld GD, Rubin E, Seckel M, Slutsky AS, Talmor D, Thompson BT, Wunsch H, Uleryk E, Brozek J, Brochard LJ; American Thoracic Society, European Society of Intensive Care Medicine, and Society of Critical Care Medicine.

Am J Respir Crit Care Med. 2017 May 1;195(9):1253-1263. doi: 10.1164/rccm.201703-0548ST. Erratum in: Am J Respir Crit Care Med. 2017 Jun 1;195(11):1540.


Comparison of methods of alert acknowledgement by critical care clinicians in the ICU setting.

Harrison AM, Thongprayoon C, Aakre CA, Jeng JY, Dziadzko MA, Gajic O, Pickering BW, Herasevich V.

PeerJ. 2017 Mar 14;5:e3083. doi: 10.7717/peerj.3083. eCollection 2017.


Randomized Clinical Trial of a Combination of an Inhaled Corticosteroid and Beta Agonist in Patients at Risk of Developing the Acute Respiratory Distress Syndrome.

Festic E, Carr GE, Cartin-Ceba R, Hinds RF, Banner-Goodspeed V, Bansal V, Asuni AT, Talmor D, Rajagopalan G, Frank RD, Gajic O, Matthay MA, Levitt JE.

Crit Care Med. 2017 May;45(5):798-805. doi: 10.1097/CCM.0000000000002284.


Ventilation in acute respiratory distress syndrome: importance of low-tidal volume.

Vallabhajosyula S, Trivedi V, Gajic O.

Ann Transl Med. 2016 Dec;4(24):496. doi: 10.21037/atm.2016.11.36. No abstract available.


Focused cardiac ultrasound in the early resuscitation of severe sepsis and septic shock: a prospective pilot study.

Sekiguchi H, Harada Y, Villarraga HR, Mankad SV, Gajic O.

J Anesth. 2017 Aug;31(4):487-493. doi: 10.1007/s00540-017-2312-8. Epub 2017 Jan 31.


Early risk factors and the role of fluid administration in developing acute respiratory distress syndrome in septic patients.

Seethala RR, Hou PC, Aisiku IP, Frendl G, Park PK, Mikkelsen ME, Chang SY, Gajic O, Sevransky J.

Ann Intensive Care. 2017 Dec;7(1):11. doi: 10.1186/s13613-017-0233-1. Epub 2017 Jan 23.


Effect of daily use of electronic checklist on physical rehabilitation consultations in critically ill patients.

Ali R, Cornelius PJ, Herasevich V, Gajic O, Kashyap R.

J Crit Care. 2017 Apr;38:357-361. doi: 10.1016/j.jcrc.2016.12.007. Epub 2016 Dec 22.


Fifty Years of Research in ARDS. Is Acute Respiratory Distress Syndrome a Preventable Disease?

Yadav H, Thompson BT, Gajic O.

Am J Respir Crit Care Med. 2017 Mar 15;195(6):725-736. doi: 10.1164/rccm.201609-1767CI. Review.


Derivation and validation of the automated search algorithms to identify cognitive impairment and dementia in electronic health records.

Amra S, O'Horo JC, Singh TD, Wilson GA, Kashyap R, Petersen R, Roberts RO, Fryer JD, Rabinstein AA, Gajic O.

J Crit Care. 2017 Feb;37:202-205. doi: 10.1016/j.jcrc.2016.09.026. Epub 2016 Oct 8.


Association between Obstructive Sleep Apnea and Acute Kidney Injury in Critically Ill Patients: A Propensity-Matched Study.

Dou L, Lan H, Reynolds DJ, Gunderson TM, Kashyap R, Gajic O, Caples S, Li G, Kashani KB.

Nephron. 2017;135(2):137-146. doi: 10.1159/000453367. Epub 2016 Dec 13.


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