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Items: 1 to 50 of 95

1.

Association of N-Terminal Pro Brain Natriuretic Peptide and Long-Term Outcome in Patients With Pulmonary Arterial Hypertension.

Chin KM, Rubin LJ, Channick R, Di Scala L, Gaine S, Galiè N, Ghofrani HA, Hoeper MM, Lang IM, McLaughlin VV, Preiss R, Simonneau G, Sitbon O, Tapson VF.

Circulation. 2019 May 21;139(21):2440-2450. doi: 10.1161/CIRCULATIONAHA.118.039360.

2.

Selexipag treatment for pulmonary arterial hypertension associated with congenital heart disease after defect correction: insights from the randomised controlled GRIPHON study.

Beghetti M, Channick RN, Chin KM, Di Scala L, Gaine S, Ghofrani HA, Hoeper MM, Lang IM, McLaughlin VV, Preiss R, Rubin LJ, Simonneau G, Sitbon O, Tapson VF, Galiè N.

Eur J Heart Fail. 2019 Mar;21(3):352-359. doi: 10.1002/ejhf.1375. Epub 2019 Jan 11.

3.

ERS statement on exercise training and rehabilitation in patients with severe chronic pulmonary hypertension.

Grünig E, Eichstaedt C, Barberà JA, Benjamin N, Blanco I, Bossone E, Cittadini A, Coghlan G, Corris P, D'Alto M, D'Andrea A, Delcroix M, de Man F, Gaine S, Ghio S, Gibbs S, Gumbiene L, Howard LS, Johnson M, Jurevičienė E, Kiely DG, Kovacs G, MacKenzie A, Marra AM, McCaffrey N, McCaughey P, Naeije R, Olschewski H, Pepke-Zaba J, Reis A, Santos M, Saxer S, Tulloh RM, Ulrich S, Vonk Noordegraaf A, Peacock AJ.

Eur Respir J. 2019 Feb 28;53(2). pii: 1800332. doi: 10.1183/13993003.00332-2018. Print 2019 Feb.

PMID:
30578391
4.

Pulmonary hypertension in chronic lung disease and hypoxia.

Nathan SD, Barbera JA, Gaine SP, Harari S, Martinez FJ, Olschewski H, Olsson KM, Peacock AJ, Pepke-Zaba J, Provencher S, Weissmann N, Seeger W.

Eur Respir J. 2019 Jan 24;53(1). pii: 1801914. doi: 10.1183/13993003.01914-2018. Print 2019 Jan.

5.

Correction to: Design and rationale of the non-interventional, edoxaban treatment in routiNe clinical prActice in patients with venous ThromboEmbolism in Europe (ETNA-VTE-Europe) study.

Cohen AT, Ay C, Hainaut P, Décousus H, Hoffmann U, Gaine S, Coppens M, da Silva PM, Jimenez D, Amann-Vesti B, Brüggenjürgen B, Levy P, Bastida JL, Vicaut E, Laeis P, Fronk EM, Zierhut W, Malzer T, Bramlage P, Agnelli G; ETNA-VTE-Europe investigators.

Thromb J. 2018 May 31;16:18. doi: 10.1186/s12959-018-0173-5. eCollection 2018.

6.

Design and rationale of the non-interventional, edoxaban treatment in routiNe clinical prActice in patients with venous ThromboEmbolism in Europe (ETNA-VTE-Europe) study.

Cohen AT, Ay C, Hainaut P, Décousus H, Hoffmann U, Gaine S, Coppens M, da Silva PM, Castro DJ, Amann-Vesti B, Brüggenjürgen B, Levy P, Bastida JL, Vicaut E, Laeis P, Fronk EM, Zierhut W, Malzer T, Bramlage P, Agnelli G; ETNA-VTE-Europe investigators.

Thromb J. 2018 May 1;16:9. doi: 10.1186/s12959-018-0163-7. eCollection 2018. Erratum in: Thromb J. 2018 May 31;16:18.

7.

Pulmonary Arterial Hypertension-Related Morbidity Is Prognostic for Mortality.

McLaughlin VV, Hoeper MM, Channick RN, Chin KM, Delcroix M, Gaine S, Ghofrani HA, Jansa P, Lang IM, Mehta S, Pulido T, Sastry BKS, Simonneau G, Sitbon O, Souza R, Torbicki A, Tapson VF, Perchenet L, Preiss R, Verweij P, Rubin LJ, Galiè N.

J Am Coll Cardiol. 2018 Feb 20;71(7):752-763. doi: 10.1016/j.jacc.2017.12.010.

8.

Targeting the Prostacyclin Pathway with Selexipag in Patients with Pulmonary Arterial Hypertension Receiving Double Combination Therapy: Insights from the Randomized Controlled GRIPHON Study.

Coghlan JG, Channick R, Chin K, Di Scala L, Galiè N, Ghofrani HA, Hoeper MM, Lang IM, McLaughlin V, Preiss R, Rubin LJ, Simonneau G, Sitbon O, Tapson VF, Gaine S.

Am J Cardiovasc Drugs. 2018 Feb;18(1):37-47. doi: 10.1007/s40256-017-0262-z.

9.

Pulmonary arterial hypertension: tailoring treatment to risk in the current era.

Gaine S, McLaughlin V.

Eur Respir Rev. 2017 Dec 20;26(146). pii: 170095. doi: 10.1183/16000617.0095-2017. Print 2017 Dec 31. Review.

10.

Temporary treatment interruptions with oral selexipag in pulmonary arterial hypertension: Insights from the Prostacyclin (PGI2) Receptor Agonist in Pulmonary Arterial Hypertension (GRIPHON) study.

Preston IR, Channick RN, Chin K, Di Scala L, Farber HW, Gaine S, Galiè N, Ghofrani HA, Hoeper MM, Lang IM, McLaughlin VV, Preiss R, Simonneau G, Sitbon O, Tapson VF, Rubin LJ.

J Heart Lung Transplant. 2018 Mar;37(3):401-408. doi: 10.1016/j.healun.2017.09.024. Epub 2017 Oct 2.

PMID:
29096938
11.

Clinical trial protocol for TRANSFORM-UK: A therapeutic open-label study of tocilizumab in the treatment of pulmonary arterial hypertension.

Hernández-Sánchez J, Harlow L, Church C, Gaine S, Knightbridge E, Bunclark K, Gor D, Bedding A, Morrell N, Corris P, Toshner M.

Pulm Circ. 2018 Jan-Mar;8(1):2045893217735820. doi: 10.1177/2045893217735820. Epub 2017 Sep 28.

PMID:
28956500
12.

The CRASH report: emergency management dilemmas facing acute physicians in patients with pulmonary arterial hypertension.

Price LC, Dimopoulos K, Marino P, Alonso-Gonzalez R, McCabe C, Kemnpy A, Swan L, Boutsikou M, Al Zahrani A, Coghlan GJ, Schreiber BE, Howard LS, Davies R, Toshner M, Pepke-Zaba J, Church AC, Peacock A, Corris PA, Lordan JL, Gaine S, Condliffe R, Kiely DG, Wort SJ.

Thorax. 2017 Nov;72(11):1035-1045. doi: 10.1136/thoraxjnl-2016-209725. Epub 2017 Sep 12. Review.

PMID:
28904006
13.

Selexipag for the treatment of connective tissue disease-associated pulmonary arterial hypertension.

Gaine S, Chin K, Coghlan G, Channick R, Di Scala L, Galiè N, Ghofrani HA, Lang IM, McLaughlin V, Preiss R, Rubin LJ, Simonneau G, Sitbon O, Tapson VF, Hoeper MM.

Eur Respir J. 2017 Aug 17;50(2). pii: 1602493. doi: 10.1183/13993003.02493-2016. Print 2017 Aug.

14.

Survival in portopulmonary hypertension: Outcomes of the United Kingdom National Pulmonary Arterial Hypertension Registry.

Sithamparanathan S, Nair A, Thirugnanasothy L, Coghlan JG, Condliffe R, Dimopoulos K, Elliot CA, Fisher AJ, Gaine S, Gibbs JSR, Gatzoulis MA, E Handler C, Howard LS, Johnson M, Kiely DG, Lordan JL, Peacock AJ, Pepke-Zaba J, Schreiber BE, Sheares KKK, Wort SJ, Corris PA; National Pulmonary Hypertension Service Research Collaboration of the United Kingdom and Ireland.

J Heart Lung Transplant. 2017 Jul;36(7):770-779. doi: 10.1016/j.healun.2016.12.014. Epub 2016 Dec 31.

PMID:
28190786
15.

Beyond a single pathway: combination therapy in pulmonary arterial hypertension.

Sitbon O, Gaine S.

Eur Respir Rev. 2016 Dec;25(142):408-417. doi: 10.1183/16000617.0085-2016. Review.

16.

Dynamic Risk Stratification of Patient Long-Term Outcome After Pulmonary Endarterectomy: Results From the United Kingdom National Cohort.

Cannon JE, Su L, Kiely DG, Page K, Toshner M, Swietlik E, Treacy C, Ponnaberanam A, Condliffe R, Sheares K, Taboada D, Dunning J, Tsui S, Ng C, Gopalan D, Screaton N, Elliot C, Gibbs S, Howard L, Corris P, Lordan J, Johnson M, Peacock A, MacKenzie-Ross R, Schreiber B, Coghlan G, Dimopoulos K, Wort SJ, Gaine S, Moledina S, Jenkins DP, Pepke-Zaba J.

Circulation. 2016 May 3;133(18):1761-71. doi: 10.1161/CIRCULATIONAHA.115.019470. Epub 2016 Apr 6.

17.

Hypoxic pulmonary hypertension in chronic lung diseases: novel vasoconstrictor pathways.

Rowan SC, Keane MP, Gaine S, McLoughlin P.

Lancet Respir Med. 2016 Mar;4(3):225-36. doi: 10.1016/S2213-2600(15)00517-2. Epub 2016 Feb 16. Review.

PMID:
26895650
18.

Long-Term Outcome of Patients With Chronic Thromboembolic Pulmonary Hypertension: Results From an International Prospective Registry.

Delcroix M, Lang I, Pepke-Zaba J, Jansa P, D'Armini AM, Snijder R, Bresser P, Torbicki A, Mellemkjaer S, Lewczuk J, Simkova I, Barberà JA, de Perrot M, Hoeper MM, Gaine S, Speich R, Gomez-Sanchez MA, Kovacs G, Jaïs X, Ambroz D, Treacy C, Morsolini M, Jenkins D, Lindner J, Dartevelle P, Mayer E, Simonneau G.

Circulation. 2016 Mar 1;133(9):859-71. doi: 10.1161/CIRCULATIONAHA.115.016522. Epub 2016 Jan 29.

PMID:
26826181
19.

Selexipag for the Treatment of Pulmonary Arterial Hypertension.

Sitbon O, Channick R, Chin KM, Frey A, Gaine S, Galiè N, Ghofrani HA, Hoeper MM, Lang IM, Preiss R, Rubin LJ, Di Scala L, Tapson V, Adzerikho I, Liu J, Moiseeva O, Zeng X, Simonneau G, McLaughlin VV; GRIPHON Investigators.

N Engl J Med. 2015 Dec 24;373(26):2522-33. doi: 10.1056/NEJMoa1503184.

20.

Recent advances in targeting the prostacyclin pathway in pulmonary arterial hypertension.

Lang IM, Gaine SP.

Eur Respir Rev. 2015 Dec;24(138):630-41. doi: 10.1183/16000617.0067-2015. Review. Erratum in: Eur Respir Rev. 2016 Mar;25(139):99. Eur Respir Rev. 2017 Jan 3;26(143):.

21.

Interferon beta related pulmonary arterial hypertension; an emerging worrying entity?

Govern EM, Judge EP, Kavanagh E, Gaine S, Lynch T.

Mult Scler Relat Disord. 2015 May;4(3):284-6. doi: 10.1016/j.msard.2015.03.008. Epub 2015 Apr 14. No abstract available.

PMID:
26008947
22.

Elevated plasma CXCL12α is associated with a poorer prognosis in pulmonary arterial hypertension.

McCullagh BN, Costello CM, Li L, O'Connell C, Codd M, Lawrie A, Morton A, Kiely DG, Condliffe R, Elliot C, McLoughlin P, Gaine S.

PLoS One. 2015 Apr 9;10(4):e0123709. doi: 10.1371/journal.pone.0123709. eCollection 2015.

23.

[Treatment goals of pulmonary hypertension].

McLaughlin VV, Gaine SP, Howard LS, Leuchte HH, Mathier MA, Mehta S, Palazzini M, Park MH, Tapson VF, Sitbon O.

Turk Kardiyol Dern Ars. 2014 Oct;42 Suppl 1:95-105. Turkish.

24.

Right heart and pulmonary vessels structure and function.

D'Alto M, Scognamiglio G, Dimopoulos K, Bossone E, Vizza D, Romeo E, Vonk-Noordergraaf A, Gaine S, Peacock A, Naeije R.

Echocardiography. 2015 Jan;32 Suppl 1:S3-10. doi: 10.1111/echo.12227. Epub 2014 Sep 19. Review.

PMID:
25244348
25.

Superior vena cava obstruction (SCVO).

Murphy D, Murphy D, Murray J, Gaine S.

Ir Med J. 2014 Feb;107(2):51-2. No abstract available.

PMID:
24654486
26.

A national house-staff audit of medical prophylaxis in medical patients for the PREVENTion of Venous ThromboEmbolism (PREVENT-VTE).

Adamali H, Suliman AM, Zaid H, O'Donoghue E, Burke A, Suliman AW, Salem M, O'Toole A, Yearoo AI, Javid S, Ullah I, Bolger K, Dunican E, McCullagh B, Curtin D, Lonergan MT, Dillon L, Murphy AW, Gaine S; PREVENT VTE Investigators.

Ir Med J. 2013 Nov-Dec;106(10):302-5.

PMID:
24579409
27.

Treatment goals of pulmonary hypertension.

McLaughlin VV, Gaine SP, Howard LS, Leuchte HH, Mathier MA, Mehta S, Palazzini M, Park MH, Tapson VF, Sitbon O.

J Am Coll Cardiol. 2013 Dec 24;62(25 Suppl):D73-81. doi: 10.1016/j.jacc.2013.10.034. Review.

28.

Detection of high-sensitivity troponin in outpatients with stable pulmonary hypertension identifies a subgroup at higher risk of adverse outcomes.

Roy AK, McCullagh BN, Segurado R, McGorrian C, Keane E, Keaney J, Fitzgibbon MN, Mahon NG, Murray PT, Gaine SP.

J Card Fail. 2014 Jan;20(1):31-7. doi: 10.1016/j.cardfail.2013.12.001. Epub 2013 Dec 12.

PMID:
24333348
29.

The need to move from 6-minute walk distance to outcome trials in pulmonary arterial hypertension.

Gaine S, Simonneau G.

Eur Respir Rev. 2013 Dec;22(130):487-94. doi: 10.1183/09059180.00006213. Review.

30.

Case 3: aspergilloma.

Murphy D, Murphy D, Murray J, Gaine S.

Ir Med J. 2013 Sep;106(8):247. No abstract available.

PMID:
24282898
31.

emPHasis-10: development of a health-related quality of life measure in pulmonary hypertension.

Yorke J, Corris P, Gaine S, Gibbs JS, Kiely DG, Harries C, Pollock V, Armstrong I.

Eur Respir J. 2014 Apr;43(4):1106-13. doi: 10.1183/09031936.00127113. Epub 2013 Nov 14.

32.

Case 1: chronic thromboembolic pulmonary hypertension (CTEPH).

Murphy DT, Murphy DM, Murray JG, Gaine SP.

Ir Med J. 2013 May;106(5):146-7. No abstract available.

PMID:
23914576
33.

Case 2: Silicosis.

Murphy DT, Murphy DM, Murray JG, Gaine SP.

Ir Med J. 2013 Jun;106(6):181-2. No abstract available.

PMID:
23909156
34.

Percutaneous atrial septostomy with modified butterfly stent and intracardiac echocardiographic guidance in a patient with syncope and refractory pulmonary arterial hypertension.

Roy AK, Gaine SP, Walsh KP.

Heart Lung Circ. 2013 Aug;22(8):668-71. doi: 10.1016/j.hlc.2013.01.005. Epub 2013 Feb 9.

PMID:
23402682
35.

Management of pulmonary arterial hypertension.

Judge EP, Gaine SP.

Curr Opin Crit Care. 2013 Feb;19(1):44-50. doi: 10.1097/MCC.0b013e32835c5137. Review.

PMID:
23242212
36.

Challenges in the diagnosis and treatment of pulmonary arterial hypertension.

Vachiéry JL, Gaine S.

Eur Respir Rev. 2012 Dec 1;21(126):313-20. doi: 10.1183/09059180.00005412. Review.

37.

Elderly patients diagnosed with idiopathic pulmonary arterial hypertension: results from the COMPERA registry.

Hoeper MM, Huscher D, Ghofrani HA, Delcroix M, Distler O, Schweiger C, Grunig E, Staehler G, Rosenkranz S, Halank M, Held M, Grohé C, Lange TJ, Behr J, Klose H, Wilkens H, Filusch A, Germann M, Ewert R, Seyfarth HJ, Olsson KM, Opitz CF, Gaine SP, Vizza CD, Vonk-Noordegraaf A, Kaemmerer H, Gibbs JS, Pittrow D.

Int J Cardiol. 2013 Sep 30;168(2):871-80. doi: 10.1016/j.ijcard.2012.10.026. Epub 2012 Nov 17.

PMID:
23164592
38.

Venous thromboembolism risk and prophylaxis in the acute hospital care setting: the Irish results of the ENDORSE study.

Murphy O, O'Connell O, Liston R, Connaughton J, Costello R, Breiden J, Doran P, Gaine S.

Ir Med J. 2012 May;105(5):140-3.

PMID:
22803491
39.

Changing demographics, epidemiology, and survival of incident pulmonary arterial hypertension: results from the pulmonary hypertension registry of the United Kingdom and Ireland.

Ling Y, Johnson MK, Kiely DG, Condliffe R, Elliot CA, Gibbs JS, Howard LS, Pepke-Zaba J, Sheares KK, Corris PA, Fisher AJ, Lordan JL, Gaine S, Coghlan JG, Wort SJ, Gatzoulis MA, Peacock AJ.

Am J Respir Crit Care Med. 2012 Oct 15;186(8):790-6. doi: 10.1164/rccm.201203-0383OC. Epub 2012 Jul 12.

PMID:
22798320
40.

Crack-ing the case: a patient with persistent delirium due to body packing with cocaine.

Ní Chróinín D, Gaine S.

Ir Med J. 2012 Apr;105(4):118-9.

PMID:
22708228
41.

A role for the CXCL12 receptor, CXCR7, in the pathogenesis of human pulmonary vascular disease.

Costello CM, McCullagh B, Howell K, Sands M, Belperio JA, Keane MP, Gaine S, McLoughlin P.

Eur Respir J. 2012 Jun;39(6):1415-24. doi: 10.1183/09031936.00044911. Epub 2011 Nov 16.

42.

Chronic thromboembolic pulmonary hypertension (CTEPH): results from an international prospective registry.

Pepke-Zaba J, Delcroix M, Lang I, Mayer E, Jansa P, Ambroz D, Treacy C, D'Armini AM, Morsolini M, Snijder R, Bresser P, Torbicki A, Kristensen B, Lewczuk J, Simkova I, Barberà JA, de Perrot M, Hoeper MM, Gaine S, Speich R, Gomez-Sanchez MA, Kovacs G, Hamid AM, Jaïs X, Simonneau G.

Circulation. 2011 Nov 1;124(18):1973-81. doi: 10.1161/CIRCULATIONAHA.110.015008. Epub 2011 Oct 3.

43.

Therapy with omalizumab for patients with severe allergic asthma improves asthma control and reduces overall healthcare costs.

Costello RW, Long DA, Gaine S, Mc Donnell T, Gilmartin JJ, Lane SJ.

Ir J Med Sci. 2011 Sep;180(3):637-41. doi: 10.1007/s11845-011-0716-2. Epub 2011 May 11.

PMID:
21557095
44.

Pulmonary arterial hypertension and the state of limbo.

Gaine SP, Humbert M.

Eur Respir Rev. 2010 Dec;19(118):264-5. doi: 10.1183/09059180.00009510. No abstract available.

45.

Registries and randomised controlled trials in pulmonary arterial hypertension: are they revealing?

Gaine S, Gomberg-Maitland M.

Int J Clin Pract Suppl. 2010 Nov;(168):1-2. doi: 10.1111/j.1742-1241.2010.02527.x. No abstract available.

PMID:
20939839
46.

Relief of chronic neuropathic pain through endothelin antagonism.

Murphy DM, O'Callaghan DS, Gaine SP.

Am J Med. 2010 Mar;123(3):e7. doi: 10.1016/j.amjmed.2009.07.025. No abstract available.

PMID:
20193818
47.

Guidelines for the diagnosis and treatment of pulmonary hypertension.

Task Force for Diagnosis and Treatment of Pulmonary Hypertension of European Society of Cardiology (ESC); European Respiratory Society (ERS); International Society of Heart and Lung Transplantation (ISHLT), Galiè N, Hoeper MM, Humbert M, Torbicki A, Vachiery JL, Barbera JA, Beghetti M, Corris P, Gaine S, Gibbs JS, Gomez-Sanchez MA, Jondeau G, Klepetko W, Opitz C, Peacock A, Rubin L, Zellweger M, Simonneau G.

Eur Respir J. 2009 Dec;34(6):1219-63. doi: 10.1183/09031936.00139009. Epub 2009 Sep 12. No abstract available.

48.

Sitaxentan-induced hepatic failure in two patients with pulmonary arterial hypertension.

Lavelle A, Sugrue R, Lawler G, Mulligan N, Kelleher B, Murphy DM, Gaine SP.

Eur Respir J. 2009 Sep;34(3):770-1. doi: 10.1183/09031936.00058409. No abstract available.

49.

Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT).

Galiè N, Hoeper MM, Humbert M, Torbicki A, Vachiery JL, Barbera JA, Beghetti M, Corris P, Gaine S, Gibbs JS, Gomez-Sanchez MA, Jondeau G, Klepetko W, Opitz C, Peacock A, Rubin L, Zellweger M, Simonneau G; ESC Committee for Practice Guidelines (CPG).

Eur Heart J. 2009 Oct;30(20):2493-537. doi: 10.1093/eurheartj/ehp297. Epub 2009 Aug 27. No abstract available. Erratum in: Eur Heart J. 2011 Apr;32(8):926.

PMID:
19713419
50.

Medical treatment of pulmonary arterial hypertension.

Adamali H, Gaine SP, Rubin LJ.

Semin Respir Crit Care Med. 2009 Aug;30(4):484-92. doi: 10.1055/s-0029-1233317. Epub 2009 Jul 24. Review.

PMID:
19634087

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