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Items: 12

1.

Drug Repurposing: The Anthelmintics Niclosamide and Nitazoxanide Are Potent TMEM16A Antagonists That Fully Bronchodilate Airways.

Miner K, Labitzke K, Liu B, Wang P, Henckels K, Gaida K, Elliott R, Chen JJ, Liu L, Leith A, Trueblood E, Hensley K, Xia XZ, Homann O, Bennett B, Fiorino M, Whoriskey J, Yu G, Escobar S, Wong M, Born TL, Budelsky A, Comeau M, Smith D, Phillips J, Johnston JA, McGivern JG, Weikl K, Powers D, Kunzelmann K, Mohn D, Hochheimer A, Sullivan JK.

Front Pharmacol. 2019 Feb 14;10:51. doi: 10.3389/fphar.2019.00051. eCollection 2019.

2.

Development of an ICOSL and BAFF bispecific inhibitor AMG 570 for systemic lupus erythematosus treatment.

Zhang M, Lee F, Knize A, Jacobsen F, Yu S, Ishida K, Miner K, Gaida K, Whoriskey J, Chen C, Gunasekaran K, Hsu H.

Clin Exp Rheumatol. 2019 Feb 15. [Epub ahead of print]

PMID:
30789152
3.

Selective ORAI1 Inhibition Ameliorates Autoimmune Central Nervous System Inflammation by Suppressing Effector but Not Regulatory T Cell Function.

Kaufmann U, Shaw PJ, Kozhaya L, Subramanian R, Gaida K, Unutmaz D, McBride HJ, Feske S.

J Immunol. 2016 Jan 15;196(2):573-85. doi: 10.4049/jimmunol.1501406. Epub 2015 Dec 16.

4.

Pharmaceutical Optimization of Peptide Toxins for Ion Channel Targets: Potent, Selective, and Long-Lived Antagonists of Kv1.3.

Murray JK, Qian YX, Liu B, Elliott R, Aral J, Park C, Zhang X, Stenkilsson M, Salyers K, Rose M, Li H, Yu S, Andrews KL, Colombero A, Werner J, Gaida K, Sickmier EA, Miu P, Itano A, McGivern J, Gegg CV, Sullivan JK, Miranda LP.

J Med Chem. 2015 Sep 10;58(17):6784-802. doi: 10.1021/acs.jmedchem.5b00495. Epub 2015 Aug 31.

PMID:
26288216
5.

Inhibition of CRAC with a human anti-ORAI1 monoclonal antibody inhibits T-cell-derived cytokine production but fails to inhibit a T-cell-dependent antibody response in the cynomolgus monkey.

Gaida K, Salimi-Moosavi H, Subramanian R, Almon V, Knize A, Zhang M, Lin FF, Nguyen HQ, Zhou L, Sullivan JK, Wong M, McBride HJ.

J Immunotoxicol. 2015 Apr-Jun;12(2):164-73. doi: 10.3109/1547691X.2014.915897. Epub 2014 Jul 3.

PMID:
24990272
6.

Perfusion computed tomography relative threshold values in definition of acute stroke lesions.

Maija R, Gaida K, Karlis K, Evija M.

Acta Radiol Short Rep. 2013 Apr 24;2(3):2047981613486099. doi: 10.1177/2047981613486099. eCollection 2013. Erratum in: Acta Radiol Open. 2015 Aug;4(8):2058460115597388.

7.

Generation and characterization of fully human monoclonal antibodies against human Orai1 for autoimmune disease.

Lin FF, Elliott R, Colombero A, Gaida K, Kelley L, Moksa A, Ho SY, Bykova E, Wong M, Rathanaswami P, Hu S, Sullivan JK, Nguyen HQ, McBride HJ.

J Pharmacol Exp Ther. 2013 May;345(2):225-38. doi: 10.1124/jpet.112.202788. Epub 2013 Mar 8.

PMID:
23475901
8.

Pharmacological effects of nonselective and subtype-selective nicotinic acetylcholine receptor agonists in animal models of persistent pain.

Gao B, Hierl M, Clarkin K, Juan T, Nguyen H, Valk Mv, Deng H, Guo W, Lehto SG, Matson D, McDermott JS, Knop J, Gaida K, Cao L, Waldon D, Albrecht BK, Boezio AA, Copeland KW, Harmange JC, Springer SK, Malmberg AB, McDonough SI.

Pain. 2010 Apr;149(1):33-49. doi: 10.1016/j.pain.2010.01.007. Epub 2010 Feb 18.

PMID:
20167427
9.

Low Level Laser Therapy--a conservative approach to the burn scar?

Gaida K, Koller R, Isler C, Aytekin O, Al-Awami M, Meissl G, Frey M.

Burns. 2004 Jun;30(4):362-7.

PMID:
15145195
10.

The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses.

Suh WK, Gajewska BU, Okada H, Gronski MA, Bertram EM, Dawicki W, Duncan GS, Bukczynski J, Plyte S, Elia A, Wakeham A, Itie A, Chung S, Da Costa J, Arya S, Horan T, Campbell P, Gaida K, Ohashi PS, Watts TH, Yoshinaga SK, Bray MR, Jordana M, Mak TW.

Nat Immunol. 2003 Sep;4(9):899-906. Epub 2003 Aug 17.

PMID:
12925852
11.

Potent activity of soluble B7RP-1-Fc in therapy of murine tumors in syngeneic hosts.

Ara G, Baher A, Storm N, Horan T, Baikalov C, Brisan E, Camacho R, Moore A, Goldman H, Kohno T, Cattley RC, Van G, Gaida K, Zhang M, Whoriskey JS, Fong D, Yoshinaga SK.

Int J Cancer. 2003 Feb 10;103(4):501-7.

12.

[Course of a syndrome resembling Reye syndrome associated with a recurrent oculomotor paralysis].

Mattigk G, Gaida K.

Kinderarztl Prax. 1989 Aug;57(8):381-5. German.

PMID:
2796125

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