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Items: 50

1.

NF-κB signaling regulates the generation of intermediate progenitors in the developing neocortex.

Yamanishi E, Yoon K, Alberi L, Gaiano N, Mizutani K.

Genes Cells. 2015 Sep;20(9):706-19. doi: 10.1111/gtc.12267. Epub 2015 Aug 3.

2.

The canonical Notch pathway effector RBP-J regulates neuronal plasticity and expression of GABA transporters in hippocampal networks.

Liu S, Wang Y, Worley PF, Mattson MP, Gaiano N.

Hippocampus. 2015 May;25(5):670-8. doi: 10.1002/hipo.22402. Epub 2015 Mar 27.

3.

Expression of notch proteins in pyramidal neurons in vivo.

Gaiano N, Alberi L, Liu S.

J Biol Chem. 2012 Jul 13;287(29):24595; author reply 24596. doi: 10.1074/jbc.L112.379016. No abstract available.

4.

Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer.

Xu K, Usary J, Kousis PC, Prat A, Wang DY, Adams JR, Wang W, Loch AJ, Deng T, Zhao W, Cardiff RD, Yoon K, Gaiano N, Ling V, Beyene J, Zacksenhaus E, Gridley T, Leong WL, Guidos CJ, Perou CM, Egan SE.

Cancer Cell. 2012 May 15;21(5):626-41. doi: 10.1016/j.ccr.2012.03.041.

5.

Botch promotes neurogenesis by antagonizing Notch.

Chi Z, Zhang J, Tokunaga A, Harraz MM, Byrne ST, Dolinko A, Xu J, Blackshaw S, Gaiano N, Dawson TM, Dawson VL.

Dev Cell. 2012 Apr 17;22(4):707-20. doi: 10.1016/j.devcel.2012.02.011. Epub 2012 Mar 22.

6.

Mouse B-type lamins are required for proper organogenesis but not by embryonic stem cells.

Kim Y, Sharov AA, McDole K, Cheng M, Hao H, Fan CM, Gaiano N, Ko MS, Zheng Y.

Science. 2011 Dec 23;334(6063):1706-10. doi: 10.1126/science.1211222. Epub 2011 Nov 24.

7.

Semaphorin 3E-Plexin-D1 signaling regulates VEGF function in developmental angiogenesis via a feedback mechanism.

Kim J, Oh WJ, Gaiano N, Yoshida Y, Gu C.

Genes Dev. 2011 Jul 1;25(13):1399-411. doi: 10.1101/gad.2042011.

8.

Notch in the vertebrate nervous system: an old dog with new tricks.

Pierfelice T, Alberi L, Gaiano N.

Neuron. 2011 Mar 10;69(5):840-55. doi: 10.1016/j.neuron.2011.02.031. Review.

9.

Activity-induced Notch signaling in neurons requires Arc/Arg3.1 and is essential for synaptic plasticity in hippocampal networks.

Alberi L, Liu S, Wang Y, Badie R, Smith-Hicks C, Wu J, Pierfelice TJ, Abazyan B, Mattson MP, Kuhl D, Pletnikov M, Worley PF, Gaiano N.

Neuron. 2011 Feb 10;69(3):437-44. doi: 10.1016/j.neuron.2011.01.004.

10.

Notch3 activation promotes invasive glioma formation in a tissue site-specific manner.

Pierfelice TJ, Schreck KC, Dang L, Asnaghi L, Gaiano N, Eberhart CG.

Cancer Res. 2011 Feb 1;71(3):1115-25. doi: 10.1158/0008-5472.CAN-10-0690. Epub 2011 Jan 18.

11.

The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance.

Schreck KC, Taylor P, Marchionni L, Gopalakrishnan V, Bar EE, Gaiano N, Eberhart CG.

Clin Cancer Res. 2010 Dec 15;16(24):6060-70. doi: 10.1158/1078-0432.CCR-10-1624. Erratum in: Clin Cancer Res. 2016 Jul 15;22(14 ):3700-1.

12.

Ultrasound-guided microinjection into the mouse forebrain in utero at E9.5.

Pierfelice TJ, Gaiano N.

J Vis Exp. 2010 Nov 13;(45). pii: 2047. doi: 10.3791/2047.

13.

Among γ-secretase substrates Notch1 alone is sufficient to block neurogenesis but does not confer self-renewal properties to neural stem cells.

Yang MS, Hong JS, Kim ST, Lee KY, Park KW, Kwon ST, Kweon DH, Koh YH, Gaiano N, Yoon K.

Biochem Biophys Res Commun. 2011 Jan 7;404(1):133-8. doi: 10.1016/j.bbrc.2010.11.080. Epub 2010 Nov 23.

PMID:
21108929
14.

A dynamic notch injury response activates epicardium and contributes to fibrosis repair.

Russell JL, Goetsch SC, Gaiano NR, Hill JA, Olson EN, Schneider JW.

Circ Res. 2011 Jan 7;108(1):51-9. doi: 10.1161/CIRCRESAHA.110.233262. Epub 2010 Nov 24.

15.

Neonatal stroke in mice causes long-term changes in neuronal Notch-2 expression that may contribute to prolonged injury.

Albéri L, Chi Z, Kadam SD, Mulholland JD, Dawson VL, Gaiano N, Comi AM.

Stroke. 2010 Oct;41(10 Suppl):S64-71. doi: 10.1161/STROKEAHA.110.595298.

16.

The exon junction complex component Magoh controls brain size by regulating neural stem cell division.

Silver DL, Watkins-Chow DE, Schreck KC, Pierfelice TJ, Larson DM, Burnetti AJ, Liaw HJ, Myung K, Walsh CA, Gaiano N, Pavan WJ.

Nat Neurosci. 2010 May;13(5):551-8. doi: 10.1038/nn.2527. Epub 2010 Apr 4.

17.

Preview. Meninges Play a RAdical Role in Embryonic Neural Stem Cell Regulation.

Sockanathan S, Gaiano N.

Cell Stem Cell. 2009 Nov 6;5(5):455-6. doi: 10.1016/j.stem.2009.10.010.

18.

Defining future directions in spinal cord tumor research: proceedings from the National Institutes of Health workshop.

Claus EB, Abdel-Wahab M, Burger PC, Engelhard HH, Ellison DW, Gaiano N, Gutmann DH, Heck DA, Holland EC, Jallo GI, Kruchko C, Kun LE, Maria BL, Rumboldt Z, Seminara D, Spinella GM, Stophel L, Wechsler-Reya R, Wrensch M, Gilbertson RJ.

J Neurosurg Spine. 2010 Feb;12(2):117-21. doi: 10.3171/2009.7.SPINE09137.

19.

PML: a tumor suppressor essential for neocortical development.

Schreck KC, Gaiano N.

Nat Neurosci. 2009 Feb;12(2):108-10. doi: 10.1038/nn0209-108. Review. No abstract available.

PMID:
19172164
20.

Notch, neural stem cells, and brain tumors.

Pierfelice TJ, Schreck KC, Eberhart CG, Gaiano N.

Cold Spring Harb Symp Quant Biol. 2008;73:367-75. doi: 10.1101/sqb.2008.73.013. Epub 2008 Nov 6. Review.

21.

Strange bedfellows: Reelin and Notch signaling interact to regulate cell migration in the developing neocortex.

Gaiano N.

Neuron. 2008 Oct 23;60(2):189-91. doi: 10.1016/j.neuron.2008.10.009. Review.

22.

Regulation of neural progenitor cell development in the nervous system.

Corbin JG, Gaiano N, Juliano SL, Poluch S, Stancik E, Haydar TF.

J Neurochem. 2008 Sep;106(6):2272-87. Review.

23.

Notch signaling activation in human embryonic stem cells is required for embryonic, but not trophoblastic, lineage commitment.

Yu X, Zou J, Ye Z, Hammond H, Chen G, Tokunaga A, Mali P, Li YM, Civin C, Gaiano N, Cheng L.

Cell Stem Cell. 2008 May 8;2(5):461-71. doi: 10.1016/j.stem.2008.03.001.

24.

Imaging hematopoietic precursor division in real time.

Wu M, Kwon HY, Rattis F, Blum J, Zhao C, Ashkenazi R, Jackson TL, Gaiano N, Oliver T, Reya T.

Cell Stem Cell. 2007 Nov;1(5):541-54. doi: 10.1016/j.stem.2007.08.009.

25.

Fibroblast growth factor receptor 2 plays an essential role in telencephalic progenitors.

Ever L, Zhao RJ, Eswarakumar VP, Gaiano N.

Dev Neurosci. 2008;30(5):306-18. Epub 2007 Dec 12.

PMID:
18073459
26.

Differential Notch signalling distinguishes neural stem cells from intermediate progenitors.

Mizutani K, Yoon K, Dang L, Tokunaga A, Gaiano N.

Nature. 2007 Sep 20;449(7160):351-5. Epub 2007 Aug 26.

PMID:
17721509
27.

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis.

Hellström M, Phng LK, Hofmann JJ, Wallgard E, Coultas L, Lindblom P, Alva J, Nilsson AK, Karlsson L, Gaiano N, Yoon K, Rossant J, Iruela-Arispe ML, Kalén M, Gerhardt H, Betsholtz C.

Nature. 2007 Feb 15;445(7129):776-80. Epub 2007 Jan 28.

PMID:
17259973
28.

Chalk one up for 'nature' during neocortical neurogenesis.

Mizutani K, Gaiano N.

Nat Neurosci. 2006 Jun;9(6):717-8. No abstract available.

PMID:
16732198
29.

Notch3 signaling promotes radial glial/progenitor character in the mammalian telencephalon.

Dang L, Yoon K, Wang M, Gaiano N.

Dev Neurosci. 2006;28(1-2):58-69.

PMID:
16508304
30.

Notch3 signaling initiates choroid plexus tumor formation.

Dang L, Fan X, Chaudhry A, Wang M, Gaiano N, Eberhart CG.

Oncogene. 2006 Jan 19;25(3):487-91.

PMID:
16186803
31.

Notch signaling in the mammalian central nervous system: insights from mouse mutants.

Yoon K, Gaiano N.

Nat Neurosci. 2005 Jun;8(6):709-15. Review. Erratum in: Nat Neurosci. 2005 Oct;8(10):1411.

PMID:
15917835
32.

Radial 'glial' progenitors: neurogenesis and signaling.

Ever L, Gaiano N.

Curr Opin Neurobiol. 2005 Feb;15(1):29-33. Review.

PMID:
15721741
33.

Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance.

Duncan AW, Rattis FM, DiMascio LN, Congdon KL, Pazianos G, Zhao C, Yoon K, Cook JM, Willert K, Gaiano N, Reya T.

Nat Immunol. 2005 Mar;6(3):314-22. Epub 2005 Jan 23.

34.
35.

Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning.

Corbin JG, Rutlin M, Gaiano N, Fishell G.

Development. 2003 Oct;130(20):4895-906. Epub 2003 Aug 20.

36.

Dorsoventral patterning is established in the telencephalon of mutants lacking both Gli3 and Hedgehog signaling.

Rallu M, Machold R, Gaiano N, Corbin JG, McMahon AP, Fishell G.

Development. 2002 Nov;129(21):4963-74.

37.

The role of notch in promoting glial and neural stem cell fates.

Gaiano N, Fishell G.

Annu Rev Neurosci. 2002;25:471-90. Epub 2002 Mar 25. Review.

PMID:
12052917
38.

N-terminal fatty-acylation of sonic hedgehog enhances the induction of rodent ventral forebrain neurons.

Kohtz JD, Lee HY, Gaiano N, Segal J, Ng E, Larson T, Baker DP, Garber EA, Williams KP, Fishell G.

Development. 2001 Jun;128(12):2351-63.

39.

An acylatable residue of Hedgehog is differentially required in Drosophila and mouse limb development.

Lee JD, Kraus P, Gaiano N, Nery S, Kohtz J, Fishell G, Loomis CA, Treisman JE.

Dev Biol. 2001 May 1;233(1):122-36.

40.

Spatiotemporal selectivity of response to Notch1 signals in mammalian forebrain precursors.

Chambers CB, Peng Y, Nguyen H, Gaiano N, Fishell G, Nye JS.

Development. 2001 Mar;128(5):689-702.

41.

The Gsh2 homeodomain gene controls multiple aspects of telencephalic development.

Corbin JG, Gaiano N, Machold RP, Langston A, Fishell G.

Development. 2000 Dec;127(23):5007-20.

42.

Radial glial identity is promoted by Notch1 signaling in the murine forebrain.

Gaiano N, Nye JS, Fishell G.

Neuron. 2000 May;26(2):395-404.

43.

A method for rapid gain-of-function studies in the mouse embryonic nervous system.

Gaiano N, Kohtz JD, Turnbull DH, Fishell G.

Nat Neurosci. 1999 Sep;2(9):812-9.

PMID:
10461220
44.

Transplantation as a tool to study progenitors within the vertebrate nervous system.

Gaiano N, Fishell G.

J Neurobiol. 1998 Aug;36(2):152-61. Review.

PMID:
9712301
45.

Retrovirus-mediated insertional mutagenesis in zebrafish and identification of a molecular marker for embryonic germ cells.

Amsterdam A, Yoon C, Allende M, Becker T, Kawakami K, Burgess S, Gaiano N, Hopkins N.

Cold Spring Harb Symp Quant Biol. 1997;62:437-50. Review. No abstract available.

PMID:
9598379
46.

Insertional mutagenesis in zebrafish identifies two novel genes, pescadillo and dead eye, essential for embryonic development.

Allende ML, Amsterdam A, Becker T, Kawakami K, Gaiano N, Hopkins N.

Genes Dev. 1996 Dec 15;10(24):3141-55.

47.

Insertional mutagenesis and rapid cloning of essential genes in zebrafish.

Gaiano N, Amsterdam A, Kawakami K, Allende M, Becker T, Hopkins N.

Nature. 1996 Oct 31;383(6603):829-32.

PMID:
8893009
48.

Introducing genes into zebrafish.

Gaiano N, Hopkins N.

Biochim Biophys Acta. 1996 Aug 8;1288(1):O11-4. Review. No abstract available.

PMID:
8764844
49.

Highly efficient germ-line transmission of proviral insertions in zebrafish.

Gaiano N, Allende M, Amsterdam A, Kawakami K, Hopkins N.

Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7777-82.

50.

Integration and germ-line transmission of a pseudotyped retroviral vector in zebrafish.

Lin S, Gaiano N, Culp P, Burns JC, Friedmann T, Yee JK, Hopkins N.

Science. 1994 Jul 29;265(5172):666-9.

PMID:
8036514

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