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Items: 1 to 50 of 128

1.

Lactococcus lactis subsp. lactis as a natural anti-listerial agent in the mushroom industry.

Dygico LK, O'Connor PM, Hayes M, Gahan CGM, Grogan H, Burgess CM.

Food Microbiol. 2019 Sep;82:30-35. doi: 10.1016/j.fm.2019.01.015. Epub 2019 Jan 28.

PMID:
31027787
2.

Microbial bile salt hydrolases mediate the efficacy of faecal microbiota transplant in the treatment of recurrent Clostridioides difficile infection.

Mullish BH, McDonald JAK, Pechlivanis A, Allegretti JR, Kao D, Barker GF, Kapila D, Petrof EO, Joyce SA, Gahan CGM, Glegola-Madejska I, Williams HRT, Holmes E, Clarke TB, Thursz MR, Marchesi JR.

Gut. 2019 Feb 11. pii: gutjnl-2018-317842. doi: 10.1136/gutjnl-2018-317842. [Epub ahead of print]

3.

Lactobacillus mucosae DPC 6426 as a bile-modifying and immunomodulatory microbe.

Ryan PM, Stolte EH, London LEE, Wells JM, Long SL, Joyce SA, Gahan CGM, Fitzgerald GF, Ross RP, Caplice NM, Stanton C.

BMC Microbiol. 2019 Feb 8;19(1):33. doi: 10.1186/s12866-019-1403-0.

4.

Short-term consumption of a high-fat diet increases host susceptibility to Listeria monocytogenes infection.

Las Heras V, Clooney AG, Ryan FJ, Cabrera-Rubio R, Casey PG, Hueston CM, Pinheiro J, Rudkin JK, Melgar S, Cotter PD, Hill C, Gahan CGM.

Microbiome. 2019 Jan 18;7(1):7. doi: 10.1186/s40168-019-0621-x.

5.

Gut Microbiota-Mediated Bile Acid Transformations Alter the Cellular Response to Multidrug Resistant Transporter Substrates in Vitro: Focus on P-glycoprotein.

Enright EF, Govindarajan K, Darrer R, MacSharry J, Joyce SA, Gahan CGM.

Mol Pharm. 2018 Dec 3;15(12):5711-5727. doi: 10.1021/acs.molpharmaceut.8b00875. Epub 2018 Nov 16.

PMID:
30388019
6.

Microbiome-mediated bile acid modification: Role in intestinal drug absorption and metabolism.

Enright EF, Griffin BT, Gahan CGM, Joyce SA.

Pharmacol Res. 2018 Jul;133:170-186. doi: 10.1016/j.phrs.2018.04.009. Epub 2018 Apr 13. Review.

PMID:
29660405
7.

Genomic Characterization of Listeria monocytogenes Isolates Associated with Clinical Listeriosis and the Food Production Environment in Ireland.

Hilliard A, Leong D, O'Callaghan A, Culligan EP, Morgan CA, DeLappe N, Hill C, Jordan K, Cormican M, Gahan CGM.

Genes (Basel). 2018 Mar 20;9(3). pii: E171. doi: 10.3390/genes9030171.

8.

Determinants of Reduced Genetic Capacity for Butyrate Synthesis by the Gut Microbiome in Crohn's Disease and Ulcerative Colitis.

Laserna-Mendieta EJ, Clooney AG, Carretero-Gomez JF, Moran C, Sheehan D, Nolan JA, Hill C, Gahan CGM, Joyce SA, Shanahan F, Claesson MJ.

J Crohns Colitis. 2018 Jan 24;12(2):204-216. doi: 10.1093/ecco-jcc/jjx137.

PMID:
29373727
9.

Development of a Click Beetle Luciferase Reporter System for Enhanced Bioluminescence Imaging of Listeria monocytogenes: Analysis in Cell Culture and Murine Infection Models.

Ur Rahman S, Stanton M, Casey PG, Spagnuolo A, Bensi G, Hill C, Francis KP, Tangney M, Gahan CGM.

Front Microbiol. 2017 Sep 26;8:1797. doi: 10.3389/fmicb.2017.01797. eCollection 2017.

10.

Microbiota-related Changes in Bile Acid & Tryptophan Metabolism are Associated with Gastrointestinal Dysfunction in a Mouse Model of Autism.

Golubeva AV, Joyce SA, Moloney G, Burokas A, Sherwin E, Arboleya S, Flynn I, Khochanskiy D, Moya-Pérez A, Peterson V, Rea K, Murphy K, Makarova O, Buravkov S, Hyland NP, Stanton C, Clarke G, Gahan CGM, Dinan TG, Cryan JF.

EBioMedicine. 2017 Oct;24:166-178. doi: 10.1016/j.ebiom.2017.09.020. Epub 2017 Sep 21.

11.

Interactions between gut bacteria and bile in health and disease.

Long SL, Gahan CGM, Joyce SA.

Mol Aspects Med. 2017 Aug;56:54-65. doi: 10.1016/j.mam.2017.06.002. Epub 2017 Jun 21. Review.

PMID:
28602676
12.

Farnesoid X Receptor Agonist Treatment Alters Bile Acid Metabolism but Exacerbates Liver Damage in a Piglet Model of Short-Bowel Syndrome.

Pereira-Fantini PM, Lapthorne S, Gahan CGM, Joyce SA, Charles J, Fuller PJ, Bines JE.

Cell Mol Gastroenterol Hepatol. 2017 Mar 6;4(1):65-74. doi: 10.1016/j.jcmgh.2017.02.008. eCollection 2017 Jul.

13.

Draft Genome Sequences of 25 Listeria monocytogenes Isolates Associated with Human Clinical Listeriosis in Ireland.

O'Callaghan A, Hilliard A, Morgan CA, Culligan EP, Leong D, DeLappe N, Hill C, Jordan K, Cormican M, Gahan CGM.

Genome Announc. 2017 May 11;5(19). pii: e00184-17. doi: 10.1128/genomeA.00184-17.

14.

Disease-Associated Changes in Bile Acid Profiles and Links to Altered Gut Microbiota.

Joyce SA, Gahan CG.

Dig Dis. 2017;35(3):169-177. doi: 10.1159/000450907. Epub 2017 Mar 1. Review.

PMID:
28249284
15.

The influence of rosuvastatin on the gastrointestinal microbiota and host gene expression profiles.

Nolan JA, Skuse P, Govindarajan K, Patterson E, Konstantinidou N, Casey PG, MacSharry J, Shanahan F, Stanton C, Hill C, Cotter PD, Joyce SA, Gahan CGM.

Am J Physiol Gastrointest Liver Physiol. 2017 May 1;312(5):G488-G497. doi: 10.1152/ajpgi.00149.2016. Epub 2017 Feb 16.

16.

Impact of Gut Microbiota-Mediated Bile Acid Metabolism on the Solubilization Capacity of Bile Salt Micelles and Drug Solubility.

Enright EF, Joyce SA, Gahan CG, Griffin BT.

Mol Pharm. 2017 Apr 3;14(4):1251-1263. doi: 10.1021/acs.molpharmaceut.6b01155. Epub 2017 Feb 24.

PMID:
28186768
17.

Unconjugated Bile Acids Influence Expression of Circadian Genes: A Potential Mechanism for Microbe-Host Crosstalk.

Govindarajan K, MacSharry J, Casey PG, Shanahan F, Joyce SA, Gahan CG.

PLoS One. 2016 Dec 1;11(12):e0167319. doi: 10.1371/journal.pone.0167319. eCollection 2016.

18.

The Impact of the Gut Microbiota on Drug Metabolism and Clinical Outcome.

Enright EF, Gahan CG, Joyce SA, Griffin BT.

Yale J Biol Med. 2016 Sep 30;89(3):375-382. eCollection 2016 Sep. Review.

19.

Draft Genome Sequences of Listeria monocytogenes Serotype 4b Strains 944 and 2993 and Serotype 1/2c Strains 198 and 2932.

Casey A, McAuliffe O, Fox EM, Leong D, Gahan CG, Jordan K.

Genome Announc. 2016 Jun 2;4(3). pii: e00482-16. doi: 10.1128/genomeA.00482-16.

20.

Shedding light on betL*: pPL2-lux mediated real-time analysis of betL* expression in Listeria monocytogenes.

Keane SM, Culligan EP, Hoffmann RF, Gahan CG, Hill C, Snelling WJ, Sleator RD.

Bioengineered. 2016 Apr 2;7(2):116-9. doi: 10.1080/21655979.2016.1171438.

21.

Short bowel syndrome (SBS)-associated alterations within the gut-liver axis evolve early and persist long-term in the piglet model of short bowel syndrome.

Pereira-Fantini PM, Bines JE, Lapthorne S, Fouhy F, Scurr M, Cotter PD, Gahan CG, Joyce SA.

J Gastroenterol Hepatol. 2016 Dec;31(12):1946-1955. doi: 10.1111/jgh.13383.

PMID:
27037739
22.

Analysis of the Impact of Rosuvastatin on Bacterial Mevalonate Production Using a UPLC-Mass Spectrometry Approach.

Nolan JA, Kinsella M, Hill C, Joyce SA, Gahan CG.

Curr Microbiol. 2016 Jul;73(1):1-8. doi: 10.1007/s00284-016-1014-z. Epub 2016 Mar 10.

PMID:
26960292
23.

Listeria monocytogenes mutants defective in gallbladder replication represent safety-enhanced vaccine delivery platforms.

Dowd GC, Bahey-El-Din M, Casey PG, Joyce SA, Hill C, Gahan CG.

Hum Vaccin Immunother. 2016 Aug 2;12(8):2059-2063. Epub 2016 Feb 23.

24.

Evidence for plasmid-mediated salt tolerance in the human gut microbiome and potential mechanisms.

Broaders E, O'Brien C, Gahan CG, Marchesi JR.

FEMS Microbiol Ecol. 2016 Mar;92(3). pii: fiw019. doi: 10.1093/femsec/fiw019. Epub 2016 Feb 4.

25.

Bile Acid Modifications at the Microbe-Host Interface: Potential for Nutraceutical and Pharmaceutical Interventions in Host Health.

Joyce SA, Gahan CG.

Annu Rev Food Sci Technol. 2016;7:313-33. doi: 10.1146/annurev-food-041715-033159. Epub 2016 Jan 11. Review.

PMID:
26772409
26.

Bacteriophage Can Prevent Encrustation and Blockage of Urinary Catheters by Proteus mirabilis.

Nzakizwanayo J, Hanin A, Alves DR, McCutcheon B, Dedi C, Salvage J, Knox K, Stewart B, Metcalfe A, Clark J, Gilmore BF, Gahan CG, Jenkins AT, Jones BV.

Antimicrob Agents Chemother. 2015 Dec 28;60(3):1530-6. doi: 10.1128/AAC.02685-15.

27.

Occurrence, Persistence, and Virulence Potential of Listeria ivanovii in Foods and Food Processing Environments in the Republic of Ireland.

Alvarez-Ordóñez A, Leong D, Morgan CA, Hill C, Gahan CG, Jordan K.

Biomed Res Int. 2015;2015:350526. doi: 10.1155/2015/350526. Epub 2015 Oct 12.

28.

Bacterial bile salt hydrolase in host metabolism: Potential for influencing gastrointestinal microbe-host crosstalk.

Joyce SA, Shanahan F, Hill C, Gahan CG.

Gut Microbes. 2014;5(5):669-74. doi: 10.4161/19490976.2014.969986. Review.

29.

Divergent evolution of the activity and regulation of the glutamate decarboxylase systems in Listeria monocytogenes EGD-e and 10403S: roles in virulence and acid tolerance.

Feehily C, Finnerty A, Casey PG, Hill C, Gahan CG, O'Byrne CP, Karatzas KA.

PLoS One. 2014 Nov 11;9(11):e112649. doi: 10.1371/journal.pone.0112649. eCollection 2014.

30.

Altered FXR signalling is associated with bile acid dysmetabolism in short bowel syndrome-associated liver disease.

Pereira-Fantini PM, Lapthorne S, Joyce SA, Dellios NL, Wilson G, Fouhy F, Thomas SL, Scurr M, Hill C, Gahan CG, Cotter PD, Fuller PJ, Hardikar W, Bines JE.

J Hepatol. 2014 Nov;61(5):1115-25. doi: 10.1016/j.jhep.2014.06.025. Epub 2014 Jul 3.

PMID:
24999016
31.

Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut.

Joyce SA, MacSharry J, Casey PG, Kinsella M, Murphy EF, Shanahan F, Hill C, Gahan CG.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):7421-6. doi: 10.1073/pnas.1323599111. Epub 2014 May 5.

32.

Vaccination studies: detection of a Listeria monocytogenes-specific T cell immune response using the ELISPOT technique.

Bahey-El-Din M, Gahan CG.

Methods Mol Biol. 2014;1157:263-74. doi: 10.1007/978-1-4939-0703-8_22.

PMID:
24792565
33.

3D imaging of the early embryonic chicken heart with focused ion beam scanning electron microscopy.

Rennie MY, Gahan CG, López CS, Thornburg KL, Rugonyi S.

Microsc Microanal. 2014 Aug;20(4):1111-9. doi: 10.1017/S1431927614000828. Epub 2014 Apr 17.

34.

Bacterial systems for gene delivery to systemic tumors.

Cummins J, Cronin M, van Pijkeren JP, Gahan CG, Tangney M.

Methods Mol Biol. 2014;1141:201-9. doi: 10.1007/978-1-4939-0363-4_13.

PMID:
24567141
35.

Listeria monocytogenes: survival and adaptation in the gastrointestinal tract.

Gahan CG, Hill C.

Front Cell Infect Microbiol. 2014 Feb 5;4:9. doi: 10.3389/fcimb.2014.00009. eCollection 2014. Review.

36.

The gut microbiota and the metabolic health of the host.

Joyce SA, Gahan CG.

Curr Opin Gastroenterol. 2014 Mar;30(2):120-7. doi: 10.1097/MOG.0000000000000039. Review.

PMID:
24468803
37.

Two-tiered biological containment strategy for Lactococcus lactis-based vaccine or immunotherapy vectors.

Hanin A, Culligan EP, Casey PG, Bahey-El-Din M, Hill C, Gahan CG.

Hum Vaccin Immunother. 2014;10(2):333-7. doi: 10.4161/hv.26954. Epub 2013 Nov 6.

38.

A mariner transposon-based signature-tagged mutagenesis system for the analysis of oral infection by Listeria monocytogenes.

Cummins J, Casey PG, Joyce SA, Gahan CG.

PLoS One. 2013 Sep 12;8(9):e75437. doi: 10.1371/journal.pone.0075437. eCollection 2013.

39.

Mobile genetic elements of the human gastrointestinal tract: potential for spread of antibiotic resistance genes.

Broaders E, Gahan CG, Marchesi JR.

Gut Microbes. 2013 Jul-Aug;4(4):271-80. doi: 10.4161/gmic.24627. Epub 2013 Apr 12. Review.

40.

Influence of internalin A murinisation on host resistance to orally acquired listeriosis in mice.

Bergmann S, Beard PM, Pasche B, Lienenklaus S, Weiss S, Gahan CG, Schughart K, Lengeling A.

BMC Microbiol. 2013 Apr 23;13:90. doi: 10.1186/1471-2180-13-90.

41.

Virulence aspects of Listeria monocytogenes LO28 high pressure-resistant variants.

Van Boeijen IK, Casey PG, Hill C, Moezelaar R, Zwietering MH, Gahan CG, Abee T.

Microb Pathog. 2013 Jun-Jul;59-60:48-51. doi: 10.1016/j.micpath.2013.04.007. Epub 2013 Apr 17.

PMID:
23603274
42.

A mutant in the Listeria monocytogenes Fur-regulated virulence locus (frvA) induces cellular immunity and confers protection against listeriosis in mice.

McLaughlin HP, Bahey-El-Din M, Casey PG, Hill C, Gahan CG.

J Med Microbiol. 2013 Feb;62(Pt 2):185-90. doi: 10.1099/jmm.0.049114-0. Epub 2012 Oct 25.

PMID:
23105022
43.

Signature tagged mutagenesis in the functional genetic analysis of gastrointestinal pathogens.

Cummins J, Gahan CG.

Gut Microbes. 2012 Mar-Apr;3(2):93-103. doi: 10.4161/gmic.19578. Epub 2012 Mar 1. Review.

44.

HmgR, a key enzyme in the mevalonate pathway for isoprenoid biosynthesis, is essential for growth of Listeria monocytogenes EGDe.

Heuston S, Begley M, Davey MS, Eberl M, Casey PG, Hill C, Gahan CG.

Microbiology. 2012 Jul;158(Pt 7):1684-93. doi: 10.1099/mic.0.056069-0. Epub 2012 Apr 13.

PMID:
22504435
45.

Isoprenoid biosynthesis in bacterial pathogens.

Heuston S, Begley M, Gahan CG, Hill C.

Microbiology. 2012 Jun;158(Pt 6):1389-401. doi: 10.1099/mic.0.051599-0. Epub 2012 Mar 30. Review.

PMID:
22466083
46.

A putative P-type ATPase required for virulence and resistance to haem toxicity in Listeria monocytogenes.

McLaughlin HP, Xiao Q, Rea RB, Pi H, Casey PG, Darby T, Charbit A, Sleator RD, Joyce SA, Cowart RE, Hill C, Klebba PE, Gahan CG.

PLoS One. 2012;7(2):e30928. doi: 10.1371/journal.pone.0030928. Epub 2012 Feb 21.

47.

High resolution in vivo bioluminescent imaging for the study of bacterial tumour targeting.

Cronin M, Akin AR, Collins SA, Meganck J, Kim JB, Baban CK, Joyce SA, van Dam GM, Zhang N, van Sinderen D, O'Sullivan GC, Kasahara N, Gahan CG, Francis KP, Tangney M.

PLoS One. 2012;7(1):e30940. doi: 10.1371/journal.pone.0030940. Epub 2012 Jan 25.

48.

The bacterial lux reporter system: applications in bacterial localisation studies.

Gahan CG.

Curr Gene Ther. 2012 Feb 1;12(1):12-9. Review.

PMID:
22263920
49.

A novel host-responsive sensor mediates virulence and type III secretion during Pseudomonas aeruginosa-host cell interactions.

O'Callaghan J, Reen FJ, Adams C, Casey PG, Gahan CG, O'Gara F.

Microbiology. 2012 Apr;158(Pt 4):1057-70. doi: 10.1099/mic.0.056127-0. Epub 2012 Jan 19.

PMID:
22262100
50.

Investigation of the role of ZurR in the physiology and pathogenesis of Listeria monocytogenes.

Dowd GC, Casey PG, Begley M, Hill C, Gahan CG.

FEMS Microbiol Lett. 2012 Feb;327(2):118-25. doi: 10.1111/j.1574-6968.2011.02472.x. Epub 2011 Dec 20.

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