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The Role of Angiotensin II in Parietal Epithelial Cell Proliferation and Crescent Formation in Glomerular Diseases.

Rizzo P, Novelli R, Rota C, Gagliardini E, Ruggiero B, Rottoli D, Benigni A, Remuzzi G.

Am J Pathol. 2017 Nov;187(11):2441-2450. doi: 10.1016/j.ajpath.2017.07.004. Epub 2017 Aug 12.


Another Piece of the Puzzle of Podocyte B7-1 Expression: Lupus Nephritis.

Novelli R, Gagliardini E, Ruggiero B, Benigni A, Remuzzi G.

Nephron. 2016;133(2):129-38. doi: 10.1159/000446324. Epub 2016 May 21.


ID16B: a hard X-ray nanoprobe beamline at the ESRF for nano-analysis.

Martínez-Criado G, Villanova J, Tucoulou R, Salomon D, Suuronen JP, Labouré S, Guilloud C, Valls V, Barrett R, Gagliardini E, Dabin Y, Baker R, Bohic S, Cohen C, Morse J.

J Synchrotron Radiat. 2016 Jan;23(1):344-52. doi: 10.1107/S1600577515019839. Epub 2016 Jan 1.


Any value of podocyte B7-1 as a biomarker in human MCD and FSGS?

Novelli R, Gagliardini E, Ruggiero B, Benigni A, Remuzzi G.

Am J Physiol Renal Physiol. 2016 Mar 1;310(5):F335-41. doi: 10.1152/ajprenal.00510.2015. Epub 2015 Dec 23.


B7-1 Is Not Induced in Podocytes of Human and Experimental Diabetic Nephropathy.

Gagliardini E, Novelli R, Corna D, Zoja C, Ruggiero B, Benigni A, Remuzzi G.

J Am Soc Nephrol. 2016 Apr;27(4):999-1005. doi: 10.1681/ASN.2015030266. Epub 2015 Aug 28.


Mitochondrial-dependent Autoimmunity in Membranous Nephropathy of IgG4-related Disease.

Buelli S, Perico L, Galbusera M, Abbate M, Morigi M, Novelli R, Gagliardini E, Tentori C, Rottoli D, Sabadini E, Saito T, Kawano M, Saeki T, Zoja C, Remuzzi G, Benigni A.

EBioMedicine. 2015 Mar 6;2(5):456-66. doi: 10.1016/j.ebiom.2015.03.003. eCollection 2015 May.


Regression of Renal Disease by Angiotensin II Antagonism Is Caused by Regeneration of Kidney Vasculature.

Remuzzi A, Sangalli F, Macconi D, Tomasoni S, Cattaneo I, Rizzo P, Bonandrini B, Bresciani E, Longaretti L, Gagliardini E, Conti S, Benigni A, Remuzzi G.

J Am Soc Nephrol. 2016 Mar;27(3):699-705. doi: 10.1681/ASN.2014100971. Epub 2015 Jun 26.


Et and diabetic nephropathy: preclinical and clinical studies.

Gagliardini E, Zoja C, Benigni A.

Semin Nephrol. 2015 Mar;35(2):188-96. doi: 10.1016/j.semnephrol.2015.03.003. Review.


Anti-Phospholipase A2 Receptor Antibody Titer Predicts Post-Rituximab Outcome of Membranous Nephropathy.

Ruggenenti P, Debiec H, Ruggiero B, Chianca A, Pellé T, Gaspari F, Suardi F, Gagliardini E, Orisio S, Benigni A, Ronco P, Remuzzi G.

J Am Soc Nephrol. 2015 Oct;26(10):2545-58. doi: 10.1681/ASN.2014070640. Epub 2015 Mar 24.


Drugs to foster kidney regeneration in experimental animals and humans.

Gagliardini E, Benigni A.

Nephron Exp Nephrol. 2014;126(2):91. doi: 10.1159/000360675. Epub 2014 May 19. Review.


An unanticipated role for survivin in organ transplant damage.

Cassis P, Solini S, Azzollini N, Aiello S, Rocchetta F, Conti S, Novelli R, Gagliardini E, Mister M, Rapezzi F, Rapezzi S, Benigni A, Remuzzi G, Conway EM, Noris M.

Am J Transplant. 2014 May;14(5):1046-60. doi: 10.1111/ajt.12677. Epub 2014 Apr 14.


Abatacept in B7-1-positive proteinuric kidney disease.

Benigni A, Gagliardini E, Remuzzi G.

N Engl J Med. 2014 Mar 27;370(13):1261-3. doi: 10.1056/NEJMc1400502. No abstract available. Erratum in: N Engl J Med. 2015 Jan 8;372(2):197.


β-arrestin-1 drives endothelin-1-mediated podocyte activation and sustains renal injury.

Buelli S, Rosanò L, Gagliardini E, Corna D, Longaretti L, Pezzotta A, Perico L, Conti S, Rizzo P, Novelli R, Morigi M, Zoja C, Remuzzi G, Bagnato A, Benigni A.

J Am Soc Nephrol. 2014 Mar;25(3):523-33. doi: 10.1681/ASN.2013040362. Epub 2013 Dec 26.


Nature and mediators of parietal epithelial cell activation in glomerulonephritides of human and rat.

Rizzo P, Perico N, Gagliardini E, Novelli R, Alison MR, Remuzzi G, Benigni A.

Am J Pathol. 2013 Dec;183(6):1769-1778. doi: 10.1016/j.ajpath.2013.08.008. Epub 2013 Oct 1.


Angiotensin II contributes to diabetic renal dysfunction in rodents and humans via Notch1/Snail pathway.

Gagliardini E, Perico N, Rizzo P, Buelli S, Longaretti L, Perico L, Tomasoni S, Zoja C, Macconi D, Morigi M, Remuzzi G, Benigni A.

Am J Pathol. 2013 Jul;183(1):119-30. doi: 10.1016/j.ajpath.2013.03.025. Epub 2013 May 23.


Mesenchymal stem cell therapy promotes renal repair by limiting glomerular podocyte and progenitor cell dysfunction in adriamycin-induced nephropathy.

Zoja C, Garcia PB, Rota C, Conti S, Gagliardini E, Corna D, Zanchi C, Bigini P, Benigni A, Remuzzi G, Morigi M.

Am J Physiol Renal Physiol. 2012 Nov 1;303(9):F1370-81. doi: 10.1152/ajprenal.00057.2012. Epub 2012 Sep 5.


A novel strategy to enhance mesenchymal stem cell migration capacity and promote tissue repair in an injury specific fashion.

Xinaris C, Morigi M, Benedetti V, Imberti B, Fabricio AS, Squarcina E, Benigni A, Gagliardini E, Remuzzi G.

Cell Transplant. 2013;22(3):423-36. doi: 10.3727/096368912X653246. Epub 2012 Aug 10.


Erythropoietin, but not the correction of anemia alone, protects from chronic kidney allograft injury.

Cassis P, Gallon L, Benigni A, Mister M, Pezzotta A, Solini S, Gagliardini E, Cugini D, Abbate M, Aiello S, Rocchetta F, Scudeletti P, Perico N, Noris M, Remuzzi G.

Kidney Int. 2012 May;81(9):903-18. doi: 10.1038/ki.2011.473. Epub 2012 Feb 8.


Human amniotic fluid stem cell preconditioning improves their regenerative potential.

Rota C, Imberti B, Pozzobon M, Piccoli M, De Coppi P, Atala A, Gagliardini E, Xinaris C, Benedetti V, Fabricio AS, Squarcina E, Abbate M, Benigni A, Remuzzi G, Morigi M.

Stem Cells Dev. 2012 Jul 20;21(11):1911-23. doi: 10.1089/scd.2011.0333. Epub 2011 Dec 23.


Endothelin in chronic proteinuric kidney disease.

Gagliardini E, Buelli S, Benigni A.

Contrib Nephrol. 2011;172:171-184. doi: 10.1159/000328697. Epub 2011 Aug 30. Review.


Inhibiting angiotensin-converting enzyme promotes renal repair by limiting progenitor cell proliferation and restoring the glomerular architecture.

Benigni A, Morigi M, Rizzo P, Gagliardini E, Rota C, Abbate M, Ghezzi S, Remuzzi A, Remuzzi G.

Am J Pathol. 2011 Aug;179(2):628-38. doi: 10.1016/j.ajpath.2011.04.003. Epub 2011 Jun 2.


Both darbepoetin alfa and carbamylated erythropoietin prevent kidney graft dysfunction due to ischemia/reperfusion in rats.

Cassis P, Azzollini N, Solini S, Mister M, Aiello S, Cugini D, Scudeletti P, Gagliardini E, Abbate M, Gallon L, Remuzzi G, Noris M.

Transplantation. 2011 Aug 15;92(3):271-9. doi: 10.1097/TP.0b013e3182241106.


Membranous nephropathy associated with IgG4-related disease.

Cravedi P, Abbate M, Gagliardini E, Galbusera M, Buelli S, Sabadini E, Marasà M, Beck LH Jr, Salant DJ, Benigni A, D'Agati V, Remuzzi G.

Am J Kidney Dis. 2011 Aug;58(2):272-5. doi: 10.1053/j.ajkd.2011.05.002. Epub 2011 Jun 12.


Rabbit anti-rat thymocyte immunoglobulin preserves renal function during ischemia/reperfusion injury in rat kidney transplantation.

Aiello S, Cassis P, Mister M, Solini S, Rocchetta F, Abbate M, Gagliardini E, Benigni A, Remuzzi G, Noris M.

Transpl Int. 2011 Aug;24(8):829-38. doi: 10.1111/j.1432-2277.2011.01263.x. Epub 2011 May 5.


Imaging of the porous ultrastructure of the glomerular epithelial filtration slit.

Gagliardini E, Conti S, Benigni A, Remuzzi G, Remuzzi A.

J Am Soc Nephrol. 2010 Dec;21(12):2081-9. doi: 10.1681/ASN.2010020199. Epub 2010 Oct 28.


Adding a statin to a combination of ACE inhibitor and ARB normalizes proteinuria in experimental diabetes, which translates into full renoprotection.

Zoja C, Corna D, Gagliardini E, Conti S, Arnaboldi L, Benigni A, Remuzzi G.

Am J Physiol Renal Physiol. 2010 Nov;299(5):F1203-11. doi: 10.1152/ajprenal.00045.2010. Epub 2010 Aug 18.


Unlike each drug alone, lisinopril if combined with avosentan promotes regression of renal lesions in experimental diabetes.

Gagliardini E, Corna D, Zoja C, Sangalli F, Carrara F, Rossi M, Conti S, Rottoli D, Longaretti L, Remuzzi A, Remuzzi G, Benigni A.

Am J Physiol Renal Physiol. 2009 Nov;297(5):F1448-56. doi: 10.1152/ajprenal.00340.2009. Epub 2009 Aug 12.


Podocyte repopulation contributes to regression of glomerular injury induced by ACE inhibition.

Macconi D, Sangalli F, Bonomelli M, Conti S, Condorelli L, Gagliardini E, Remuzzi G, Remuzzi A.

Am J Pathol. 2009 Mar;174(3):797-807. doi: 10.2353/ajpath.2009.080227. Epub 2009 Jan 22.


Proteasomal processing of albumin by renal dendritic cells generates antigenic peptides.

Macconi D, Chiabrando C, Schiarea S, Aiello S, Cassis L, Gagliardini E, Noris M, Buelli S, Zoja C, Corna D, Mele C, Fanelli R, Remuzzi G, Benigni A.

J Am Soc Nephrol. 2009 Jan;20(1):123-30. doi: 10.1681/ASN.2007111233. Epub 2008 Dec 17.


Propionyl-L-carnitine prevents early graft dysfunction in allogeneic rat kidney transplantation.

Azzollini N, Cugini D, Cassis P, Pezzotta A, Gagliardini E, Abbate M, Arduini A, Peschechera A, Remuzzi G, Noris M.

Kidney Int. 2008 Dec;74(11):1420-8. doi: 10.1038/ki.2008.399. Epub 2008 Aug 13.


Effects of rituximab on morphofunctional abnormalities of membranous glomerulopathy.

Ruggenenti P, Cravedi P, Sghirlanzoni MC, Gagliardini E, Conti S, Gaspari F, Marchetti G, Abbate M, Remuzzi G.

Clin J Am Soc Nephrol. 2008 Nov;3(6):1652-9. doi: 10.2215/CJN.01730408. Epub 2008 Aug 6.


Sirolimus versus cyclosporine therapy increases circulating regulatory T cells, but does not protect renal transplant patients given alemtuzumab induction from chronic allograft injury.

Ruggenenti P, Perico N, Gotti E, Cravedi P, D'Agati V, Gagliardini E, Abbate M, Gaspari F, Cattaneo D, Noris M, Casiraghi F, Todeschini M, Cugini D, Conti S, Remuzzi G.

Transplantation. 2007 Oct 27;84(8):956-64.


Immunophenotypic analysis of cellular infiltrate of renal allograft biopsies in patients with acute rejection after induction with alemtuzumab (Campath-1H).

Gallon L, Gagliardini E, Benigni A, Kaufman D, Waheed A, Noris M, Remuzzi G.

Clin J Am Soc Nephrol. 2006 May;1(3):539-45. Epub 2006 Apr 5.


Involvement of renal tubular Toll-like receptor 9 in the development of tubulointerstitial injury in systemic lupus.

Benigni A, Caroli C, Longaretti L, Gagliardini E, Zoja C, Galbusera M, Moioli D, Romagnani P, Tincani A, Andreoli L, Remuzzi G.

Arthritis Rheum. 2007 May;56(5):1569-78.


Therapeutic potential of TGF-beta inhibition in chronic renal failure.

Gagliardini E, Benigni A.

Expert Opin Biol Ther. 2007 Mar;7(3):293-304. Review.


Beneficial effect of TGFbeta antagonism in treating diabetic nephropathy depends on when treatment is started.

Benigni A, Zoja C, Campana M, Corna D, Sangalli F, Rottoli D, Gagliardini E, Conti S, Ledbetter S, Remuzzi G.

Nephron Exp Nephrol. 2006;104(4):e158-68. Epub 2006 Aug 10.


Transcriptional regulation of nephrin gene by peroxisome proliferator-activated receptor-gamma agonist: molecular mechanism of the antiproteinuric effect of pioglitazone.

Benigni A, Zoja C, Tomasoni S, Campana M, Corna D, Zanchi C, Gagliardini E, Garofano E, Rottoli D, Ito T, Remuzzi G.

J Am Soc Nephrol. 2006 Jun;17(6):1624-32. Epub 2006 May 10.


ACE inhibition reduces glomerulosclerosis and regenerates glomerular tissue in a model of progressive renal disease.

Remuzzi A, Gagliardini E, Sangalli F, Bonomelli M, Piccinelli M, Benigni A, Remuzzi G.

Kidney Int. 2006 Apr;69(7):1124-30.


Role of anti-TGF-beta antibodies in the treatment of renal injury.

Gagliardini E, Benigni A.

Cytokine Growth Factor Rev. 2006 Feb-Apr;17(1-2):89-96. Epub 2005 Oct 28. Review.


Severe early acute humoral rejection resulting in allograft loss in a renal transplant recipient with Campath-1H induction therapy.

Hill P, Gagliardini E, Ruggenenti P, Remuzzi G.

Nephrol Dial Transplant. 2005 Aug;20(8):1741-4. Epub 2005 May 3. No abstract available.


Inhibition of the chemokine receptor CXCR2 prevents kidney graft function deterioration due to ischemia/reperfusion.

Cugini D, Azzollini N, Gagliardini E, Cassis P, Bertini R, Colotta F, Noris M, Remuzzi G, Benigni A.

Kidney Int. 2005 May;67(5):1753-61.


Targeted deletion of angiotensin II type 1A receptor does not protect mice from progressive nephropathy of overload proteinuria.

Benigni A, Corna D, Zoja C, Longaretti L, Gagliardini E, Perico N, Coffman TM, Remuzzi G.

J Am Soc Nephrol. 2004 Oct;15(10):2666-74.


Selective impairment of gene expression and assembly of nephrin in human diabetic nephropathy.

Benigni A, Gagliardini E, Tomasoni S, Abbate M, Ruggenenti P, Kalluri R, Remuzzi G.

Kidney Int. 2004 Jun;65(6):2193-200.


Favorable effect of cotransfection with TGF-beta and CTLA4Ig of the donor kidney on allograft survival.

Tomasoni S, Longaretti L, Azzollini N, Gagliardini E, Mister M, Buehler T, Remuzzi G, Benigni A.

Am J Nephrol. 2004 May-Jun;24(3):275-83. Epub 2004 Mar 30.


ACE inhibition limits chronic injury of kidney transplant even with treatment started when lesions are established.

Noris M, Mister M, Pezzotta A, Azzollini N, Cassis P, Benigni A, Gagliardini E, Perico N, Remuzzi G.

Kidney Int. 2003 Dec;64(6):2253-61.


Targeted downregulation of extracellular nephrin in human IgA nephropathy.

Gagliardini E, Benigni A, Tomasoni S, Abbate M, Kalluri R, Remuzzi G.

Am J Nephrol. 2003 Jul-Aug;23(4):277-86. Epub 2003 Jul 9.


Add-on anti-TGF-beta antibody to ACE inhibitor arrests progressive diabetic nephropathy in the rat.

Benigni A, Zoja C, Corna D, Zatelli C, Conti S, Campana M, Gagliardini E, Rottoli D, Zanchi C, Abbate M, Ledbetter S, Remuzzi G.

J Am Soc Nephrol. 2003 Jul;14(7):1816-24.


Effect of angiotensin II antagonism on the regression of kidney disease in the rat.

Remuzzi A, Gagliardini E, Donadoni C, Fassi A, Sangalli F, Lepre MS, Remuzzi G, Benigni A.

Kidney Int. 2002 Sep;62(3):885-94.


Propionyl-L-carnitine prevents renal function deterioration due to ischemia/reperfusion.

Mister M, Noris M, Szymczuk J, Azzollini N, Aiello S, Abbate M, Trochimowicz L, Gagliardini E, Arduini A, Perico N, Remuzzi G.

Kidney Int. 2002 Mar;61(3):1064-78.

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