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Insights on multimorbidity and associated health service use and costs from three population-based studies of older adults in Ontario with diabetes, dementia and stroke.

Griffith LE, Gruneir A, Fisher K, Panjwani D, Gafni A, Patterson C, Markle-Reid M, Ploeg J.

BMC Health Serv Res. 2019 May 16;19(1):313. doi: 10.1186/s12913-019-4149-3.


Reporting quality of pilot clinical trials in chronic kidney disease patients on hemodialysis: a methodological survey.

Kosa SD, Monize J, Leenus A, Leenus S, Samra S, Szwiega S, Shi D, Valvasori S, Gafni A, Lok CE, Thabane L.

Pilot Feasibility Stud. 2019 Apr 6;5:53. doi: 10.1186/s40814-019-0436-3. eCollection 2019.


Nutritional Mobile Applications for CKD Patients: Systematic Review.

Kosa SD, Monize J, D'Souza M, Joshi A, Philip K, Reza S, Samra S, Serrago B, Thabane L, Gafni A, Lok CE.

Kidney Int Rep. 2018 Nov 29;4(3):399-407. doi: 10.1016/j.ekir.2018.11.016. eCollection 2019 Mar.


Authors' reply re: Urinary stress incontinence and other maternal outcomes 2 years after caesarean or vaginal birth for twin pregnancy: a multicentre randomised trial.

Hutton EK, Hannah ME, Willan A, Ross S, Armson A, Gafni A, Joseph KS, Mangoff K, Ohlsson A, Sanchez J, Asztalos E, Barrett J; Twin Birth Study Collaborative Group.

BJOG. 2019 Mar;126(4):547. doi: 10.1111/1471-0528.15582. No abstract available.


The cost implication of primary prevention in the HOPE 3 trial.

Lamy A, Lonn E, Tong W, Swaminathan B, Jung H, Gafni A, Bosch J, Yusuf S.

Eur Heart J Qual Care Clin Outcomes. 2019 Jul 1;5(3):266-271. doi: 10.1093/ehjqcco/qcz001.


CHIPS-Child: Testing the developmental programming hypothesis in the offspring of the CHIPS trial.

Magee LA, Synnes AR, von Dadelszen P, Hutfield AM, Chanoine JP, Côté AM, Devlin AM, Dorling J, Gafni A, Ganzevoort W, Helewa ME, Hutton EK, Koren G, Lee SK, Mcarthur D, Rey E, Robinson WP, Roseboom TJ, Singer J, Wilson S, Moutquin JM; CHIPS-Child Study Group (Table S1).

Pregnancy Hypertens. 2018 Oct;14:15-22. doi: 10.1016/j.preghy.2018.04.021. Epub 2018 May 19.


Measuring Public Preferences for Health Outcomes and Expenditures in a Context of Healthcare Resource Re-Allocation.

Krucien N, Pelletier-Fleury N, Gafni A.

Pharmacoeconomics. 2019 Mar;37(3):407-417. doi: 10.1007/s40273-018-0751-1.


Postoperative complications in elderly patients following pancreaticoduodenectomy lead to increased postoperative mortality and costs. A retrospective cohort study.

Yuan F, Essaji Y, Belley-Cote EP, Gafni A, Latchupatula L, Ruo L, Serrano PE.

Int J Surg. 2018 Dec;60:204-209. doi: 10.1016/j.ijsu.2018.11.016. Epub 2018 Nov 20.


The evolution of GRADE (part 3): A framework built on science or faith?

Mercuri M, Gafni A.

J Eval Clin Pract. 2018 Oct;24(5):1223-1231. doi: 10.1111/jep.13016. Epub 2018 Jul 31.


The evolution of GRADE (part 2): Still searching for a theoretical and/or empirical basis for the GRADE framework.

Mercuri M, Gafni A.

J Eval Clin Pract. 2018 Oct;24(5):1211-1222. doi: 10.1111/jep.12997. Epub 2018 Jul 17.


The evolution of GRADE (part 1): Is there a theoretical and/or empirical basis for the GRADE framework?

Mercuri M, Gafni A.

J Eval Clin Pract. 2018 Oct;24(5):1203-1210. doi: 10.1111/jep.12998. Epub 2018 Jul 16.


A protocol for a Canadian prospective observational study of decision-making on active surveillance or surgery for low-risk papillary thyroid cancer.

Sawka AM, Ghai S, Tomlinson G, Rotstein L, Gilbert R, Gullane P, Pasternak J, Brown D, de Almeida J, Irish J, Chepeha D, Higgins K, Monteiro E, Jones JM, Gafni A, Goldstein DP.

BMJ Open. 2018 Apr 12;8(4):e020298. doi: 10.1136/bmjopen-2017-020298.


Community Program Improves Quality of Life and Self-Management in Older Adults with Diabetes Mellitus and Comorbidity.

Markle-Reid M, Ploeg J, Fraser KD, Fisher KA, Bartholomew A, Griffith LE, Miklavcic J, Gafni A, Thabane L, Upshur R.

J Am Geriatr Soc. 2018 Feb;66(2):263-273. doi: 10.1111/jgs.15173. Epub 2017 Nov 27.


Hemodialysis Infection Prevention Protocols Ontario-Shower Technique (HIPPO-ST): A Pilot Randomized Trial.

Kosa SD, Gafni A, House AA, Lawrence J, Moist L, Nathoo B, Tam P, Sarabia A, Thabane L, Wu G, Lok CE.

Kidney Int Rep. 2016 Nov 8;2(2):228-238. doi: 10.1016/j.ekir.2016.11.001. eCollection 2017 Mar.


Predicting tissue plasminogen activator use and success in in-center hemodialysis patients.

Kosa SD, Ye C, Thabane L, Gafni A, Lok CE.

J Vasc Access. 2018 Mar;19(2):146-152. doi: 10.5301/jva.5000785. Epub 2018 Feb 19.


Examining the role of the physician as a source of variation: Are physician-related variations necessarily unwarranted?

Mercuri M, Gafni A.

J Eval Clin Pract. 2018 Feb;24(1):145-151. doi: 10.1111/jep.12770. Epub 2017 May 29. Review.


The TRIO Framework: Conceptual insights into family caregiver involvement and influence throughout cancer treatment decision-making.

Laidsaar-Powell R, Butow P, Charles C, Gafni A, Entwistle V, Epstein R, Juraskova I.

Patient Educ Couns. 2017 Nov;100(11):2035-2046. doi: 10.1016/j.pec.2017.05.014. Epub 2017 May 5. Review.


Attributing a monetary value to patients' time: A contingent valuation approach.

van den Berg B, Gafni A, Portrait F.

Soc Sci Med. 2017 Apr;179:182-190. doi: 10.1016/j.socscimed.2017.02.025. Epub 2017 Feb 20.


The ACHRU-CPP versus usual care for older adults with type-2 diabetes and multiple chronic conditions and their family caregivers: study protocol for a randomized controlled trial.

Markle-Reid M, Ploeg J, Fraser KD, Fisher KA, Akhtar-Danesh N, Bartholomew A, Gafni A, Gruneir A, Hirst SP, Kaasalainen S, Stradiotto CK, Miklavcic J, Rojas-Fernandez C, Sadowski CA, Thabane L, Triscott JA, Upshur R.

Trials. 2017 Feb 6;18(1):55. doi: 10.1186/s13063-017-1795-9.


The Aging, Community and Health Research Unit-Community Partnership Program for older adults with type 2 diabetes and multiple chronic conditions: a feasibility study.

Markle-Reid M, Ploeg J, Fisher K, Reimer H, Kaasalainen S, Gafni A, Gruneir A, Kirkconnell R, Marzouk S, Akhtar-Danesh N, Thabane L, Rojas-Fernandez C, Upshur R.

Pilot Feasibility Stud. 2016 May 9;2:24. eCollection 2016.


Comorbidity and its relationship with health service use and cost in community-living older adults with diabetes: A population-based study in Ontario, Canada.

Fisher K, Griffith L, Gruneir A, Panjwani D, Gandhi S, Sheng LL, Gafni A, Chris P, Markle-Reid M, Ploeg J.

Diabetes Res Clin Pract. 2016 Dec;122:113-123. doi: 10.1016/j.diabres.2016.10.009. Epub 2016 Oct 20.


Patterns of health service use in community living older adults with dementia and comorbid conditions: a population-based retrospective cohort study in Ontario, Canada.

Griffith LE, Gruneir A, Fisher K, Panjwani D, Gandhi S, Sheng L, Gafni A, Patterson C, Markle-Reid M, Ploeg J.

BMC Geriatr. 2016 Oct 26;16(1):177.


Increasing comorbidity and health services utilization in older adults with prior stroke.

Gruneir A, Griffith LE, Fisher K, Panjwani D, Gandhi S, Sheng L, Patterson C, Gafni A, Ploeg J, Markle-Reid M.

Neurology. 2016 Nov 15;87(20):2091-2098. Epub 2016 Oct 19.


Women's views and postpartum follow-up in the CHIPS Trial (Control of Hypertension in Pregnancy Study).

Vidler M, Magee LA, von Dadelszen P, Rey E, Ross S, Asztalos E, Murphy KE, Menzies J, Sanchez J, Singer J, Gafni A, Gruslin A, Helewa M, Hutton E, Lee SK, Lee T, Logan AG, Ganzevoort W, Welch R, Thornton JG, Moutquin JM; CHIPS Study Group.

Eur J Obstet Gynecol Reprod Biol. 2016 Nov;206:105-113. doi: 10.1016/j.ejogrb.2016.07.509. Epub 2016 Sep 10.


The CHIPS Randomized Controlled Trial (Control of Hypertension in Pregnancy Study): Is Severe Hypertension Just an Elevated Blood Pressure?

Magee LA, von Dadelszen P, Singer J, Lee T, Rey E, Ross S, Asztalos E, Murphy KE, Menzies J, Sanchez J, Gafni A, Helewa M, Hutton E, Koren G, Lee SK, Logan AG, Ganzevoort W, Welch R, Thornton JG, Moutquin JM; CHIPS Study Group*.

Hypertension. 2016 Nov;68(5):1153-1159. Epub 2016 Sep 12.


The Cost Implications of Less Tight Versus Tight Control of Hypertension in Pregnancy (CHIPS Trial).

Ahmed RJ, Gafni A, Hutton EK, Hu ZJ, Pullenayegum E, von Dadelszen P, Rey E, Ross S, Asztalos E, Murphy KE, Menzies J, Sanchez JJ, Ganzevoort W, Helewa M, Lee SK, Lee T, Logan AG, Moutquin JM, Singer J, Thornton JG, Welch R, Magee LA.

Hypertension. 2016 Oct;68(4):1049-55. doi: 10.1161/HYPERTENSIONAHA.116.07466. Epub 2016 Aug 22.


Challenges in striving to simultaneously achieve multiple resource allocation goals: the pan-Canadian Oncology Drug Review (pCODR) example.

McDonald H, Charles C, Elit L, Gafni A.

J Mark Access Health Policy. 2016 Jul 21;4. doi: 10.3402/jmahp.v4.31463. eCollection 2016.


Positron Emission Tomography-Computed Tomography (PET-CT) Versus No PET-CT in the Management of Potentially Resectable Colorectal Cancer Liver Metastases: Cost Implications of a Randomized Controlled Trial.

Serrano PE, Gafni A, Gu CS, Gulenchyn KY, Julian JA, Law C, Hendler AL, Moulton CA, Gallinger S, Levine MN.

J Oncol Pract. 2016 Jul;12(7):e765-74. doi: 10.1200/JOP.2016.011676. Epub 2016 Jun 21.


Designing, Implementing, and Evaluating Mobile Health Technologies for Managing Chronic Conditions in Older Adults: A Scoping Review.

Matthew-Maich N, Harris L, Ploeg J, Markle-Reid M, Valaitis R, Ibrahim S, Gafni A, Isaacs S.

JMIR Mhealth Uhealth. 2016 Jun 9;4(2):e29. doi: 10.2196/mhealth.5127. Review.


A review of health literacy: Definitions, interpretations, and implications for policy initiatives.

Malloy-Weir LJ, Charles C, Gafni A, Entwistle V.

J Public Health Policy. 2016 Aug;37(3):334-352. doi: 10.1057/jphp.2016.18. Epub 2016 May 19.


The Cost Implications in Ontario, Alberta, and British Columbia of Early Versus Delayed External Cephalic Version in the Early External Cephalic Version 2 (EECV2) Trial.

Ahmed RJ, Gafni A, Hutton EK; Early ECV2 Trial Collaborative Group.

J Obstet Gynaecol Can. 2016 Mar;38(3):235-245.e3. doi: 10.1016/j.jogc.2015.12.019. Epub 2016 Mar 29.


Can adverse maternal and perinatal outcomes be predicted when blood pressure becomes elevated? Secondary analyses from the CHIPS (Control of Hypertension In Pregnancy Study) randomized controlled trial.

Magee LA, von Dadelszen P, Singer J, Lee T, Rey E, Ross S, Asztalos E, Murphy KE, Menzies J, Sanchez J, Gafni A, Gruslin A, Helewa M, Hutton E, Lee SK, Logan AG, Ganzevoort W, Welch R, Thornton JG, Moutquin JM.

Acta Obstet Gynecol Scand. 2016 Jul;95(7):763-76. doi: 10.1111/aogs.12877. Epub 2016 Apr 7.


Re: Maternal outcomes at 3 months after planned caesarean section versus planned vaginal birth for twin pregnancies in the Twin Birth Study: a randomised controlled trial: Counselling is difficult when outcomes are associated with mode of delivery and not the plan of mode of delivery.

Hutton EK, Hannah ME, Ross S, Joseph KS, Ohlsson A, Asztalos E, Willan AR, Allen AC, Armson BA, Gafni A, Mangoff K, Sanchez JJ, Barrett JF; Twin Birth Study Collaborative Group.

BJOG. 2016 Mar;123(4):644. doi: 10.1111/1471-0528.13769. No abstract available.


Family involvement in cancer treatment decision-making: A qualitative study of patient, family, and clinician attitudes and experiences.

Laidsaar-Powell R, Butow P, Bu S, Charles C, Gafni A, Fisher A, Juraskova I.

Patient Educ Couns. 2016 Jul;99(7):1146-1155. doi: 10.1016/j.pec.2016.01.014. Epub 2016 Jan 28.


Twin Birth Study: 2-year neurodevelopmental follow-up of the randomized trial of planned cesarean or planned vaginal delivery for twin pregnancy.

Asztalos EV, Hannah ME, Hutton EK, Willan AR, Allen AC, Armson BA, Gafni A, Joseph KS, Ohlsson A, Ross S, Sanchez JJ, Mangoff K, Barrett JF.

Am J Obstet Gynecol. 2016 Mar;214(3):371.e1-371.e19. doi: 10.1016/j.ajog.2015.12.051. Epub 2016 Jan 29.


A randomized controlled trial of an intervention for infants' behavioral sleep problems.

Hall WA, Hutton E, Brant RF, Collet JP, Gregg K, Saunders R, Ipsiroglu O, Gafni A, Triolet K, Tse L, Bhagat R, Wooldridge J.

BMC Pediatr. 2015 Nov 13;15:181. doi: 10.1186/s12887-015-0492-7.


Availability and affordability of cardiovascular disease medicines and their effect on use in high-income, middle-income, and low-income countries: an analysis of the PURE study data.

Khatib R, McKee M, Shannon H, Chow C, Rangarajan S, Teo K, Wei L, Mony P, Mohan V, Gupta R, Kumar R, Vijayakumar K, Lear SA, Diaz R, Avezum A, Lopez-Jaramillo P, Lanas F, Yusoff K, Ismail N, Kazmi K, Rahman O, Rosengren A, Monsef N, Kelishadi R, Kruger A, Puoane T, Szuba A, Chifamba J, Temizhan A, Dagenais G, Gafni A, Yusuf S; PURE study investigators.

Lancet. 2016 Jan 2;387(10013):61-9. doi: 10.1016/S0140-6736(15)00469-9. Epub 2015 Oct 20.


Thyroid cancer patient perceptions of radioactive iodine treatment choice: Follow-up from a decision-aid randomized trial.

Sawka AM, Straus S, Rodin G, Heus L, Brierley JD, Tsang RW, Rotstein L, Ezzat S, Segal P, Gafni A, Thorpe KE, Goldstein DP.

Cancer. 2015 Oct 15;121(20):3717-26. doi: 10.1002/cncr.29548. Epub 2015 Jul 20.


Decision aid on radioactive iodine treatment for early stage papillary thyroid cancer: update to study protocol with follow-up extension.

Sawka AM, Straus S, Rodin G, Thorpe KE, Ezzat S, Gafni A, Goldstein DP.

Trials. 2015 Jul 14;16:302. doi: 10.1186/s13063-015-0819-6.


Exploring the relationship between patients' information preference style and knowledge acquisition process in a computerized patient decision aid randomized controlled trial.

Sawka AM, Straus S, Rodin G, Tsang RW, Brierley JD, Rotstein L, Segal P, Gafni A, Ezzat S, Goldstein DP.

BMC Med Inform Decis Mak. 2015 Jun 19;15:48. doi: 10.1186/s12911-015-0168-0.


On the margins of health economics: a response to 'resolving NICE'S nasty dilemma'.

Birch S, Gafni A.

Health Econ Policy Law. 2015 Apr;10(2):183-93. doi: 10.1017/S1744133114000462.


Cost implication of an early invasive strategy on weekdays and weekends in patients with acute coronary syndromes.

Lamy A, Tong WR, Bainey K, Gafni A, Rao-Melacini P, Mehta SR.

Can J Cardiol. 2015 Mar;31(3):314-9. doi: 10.1016/j.cjca.2014.11.025. Epub 2014 Dec 3.


Less-tight versus tight control of hypertension in pregnancy.

Magee LA, von Dadelszen P, Rey E, Ross S, Asztalos E, Murphy KE, Menzies J, Sanchez J, Singer J, Gafni A, Gruslin A, Helewa M, Hutton E, Lee SK, Lee T, Logan AG, Ganzevoort W, Welch R, Thornton JG, Moutquin JM.

N Engl J Med. 2015 Jan 29;372(5):407-17. doi: 10.1056/NEJMoa1404595.


Empirical relationships between health literacy and treatment decision making: a scoping review of the literature.

Malloy-Weir LJ, Charles C, Gafni A, Entwistle VA.

Patient Educ Couns. 2015 Mar;98(3):296-309. doi: 10.1016/j.pec.2014.11.004. Epub 2014 Dec 8. Review.


Is there an economic rationale for cancer drugs to have a separate reimbursement review process for resource allocation purposes?

McDonald H, Charles C, Elit L, Gafni A.

Pharmacoeconomics. 2015 Mar;33(3):235-41. doi: 10.1007/s40273-014-0238-7. Review.


When guidelines don't guide: the effect of patient context on management decisions based on clinical practice guidelines.

Mercuri M, Sherbino J, Sedran RJ, Frank JR, Gafni A, Norman G.

Acad Med. 2015 Feb;90(2):191-6. doi: 10.1097/ACM.0000000000000542.


The cost implications of off-pump versus on-pump coronary artery bypass graft surgery at one year.

Lamy A, Tong W, Devereaux PJ, Gao P, Gafni A, Singh K, Taggart D, Straka Z, Akar AR, Piegas L, Ou Y, Yusuf S.

Ann Thorac Surg. 2014 Nov;98(5):1620-5. doi: 10.1016/j.athoracsur.2014.06.046. Epub 2014 Sep 24.


Association between gestational age at birth, antenatal corticosteroids, and outcomes at 5 years: multiple courses of antenatal corticosteroids for preterm birth study at 5 years of age (MACS-5).

Asztalos E, Willan A, Murphy K, Matthews S, Ohlsson A, Saigal S, Armson A, Kelly E, Delisle MF, Gafni A, Lee S, Sananes R, Rovet J, Guselle P, Amankwah K; MACS-5 Collaborative Group.

BMC Pregnancy Childbirth. 2014 Aug 13;14:272. doi: 10.1186/1471-2393-14-272.

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