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Items: 38

1.

Hedgehog signaling and cell cycle control in differentiating erythroid progenitors.

Detmer K, Thompson AJ, Garner RE, Walker AN, Gaffield W, Dannawi H.

Blood Cells Mol Dis. 2005 Jan-Feb;34(1):60-70.

PMID:
15607701
2.

Sonic hedgehog exerts distinct, stage-specific effects on tongue and taste papilla development.

Liu HX, Maccallum DK, Edwards C, Gaffield W, Mistretta CM.

Dev Biol. 2004 Dec 15;276(2):280-300.

3.

Effects of steroidal glycoalkaloids from potatoes (Solanum tuberosum) on in vitro bovine embryo development.

Wang S, Panter KE, Gaffield W, Evans RC, Bunch TD.

Anim Reprod Sci. 2005 Feb;85(3-4):243-50.

PMID:
15581508
4.

Temporal perturbations in sonic hedgehog signaling elicit the spectrum of holoprosencephaly phenotypes.

Cordero D, Marcucio R, Hu D, Gaffield W, Tapadia M, Helms JA.

J Clin Invest. 2004 Aug;114(4):485-94.

5.

Hedgehog regulation of superficial slow muscle fibres in Xenopus and the evolution of tetrapod trunk myogenesis.

Grimaldi A, Tettamanti G, Martin BL, Gaffield W, Pownall ME, Hughes SM.

Development. 2004 Jul;131(14):3249-62. Epub 2004 Jun 16.

6.

Hedgehog signalling in colorectal tumour cells: induction of apoptosis with cyclopamine treatment.

Qualtrough D, Buda A, Gaffield W, Williams AC, Paraskeva C.

Int J Cancer. 2004 Jul 20;110(6):831-7.

7.

Biomedical applications of poisonous plant research.

James LF, Panter KE, Gaffield W, Molyneux RJ.

J Agric Food Chem. 2004 Jun 2;52(11):3211-30. Review.

PMID:
15161174
8.

Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation.

van den Brink GR, Bleuming SA, Hardwick JC, Schepman BL, Offerhaus GJ, Keller JJ, Nielsen C, Gaffield W, van Deventer SJ, Roberts DJ, Peppelenbosch MP.

Nat Genet. 2004 Mar;36(3):277-82. Epub 2004 Feb 8.

PMID:
14770182
9.

A hedgehog homolog regulates gut formation in leech (Helobdella).

Kang D, Huang F, Li D, Shankland M, Gaffield W, Weisblat DA.

Development. 2003 Apr;130(8):1645-57.

11.

Development of an enzyme-linked immunosorbent assay for the veratrum plant teratogens: cyclopamine and jervine.

Lee ST, Panter KE, Gaffield W, Stegelmeier BL.

J Agric Food Chem. 2003 Jan 29;51(3):582-6.

PMID:
12537426
12.

Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formation.

Lamm ML, Catbagan WS, Laciak RJ, Barnett DH, Hebner CM, Gaffield W, Walterhouse D, Iannaccone P, Bushman W.

Dev Biol. 2002 Sep 15;249(2):349-66.

13.

Bone patterning is altered in the regenerating zebrafish caudal fin after ectopic expression of sonic hedgehog and bmp2b or exposure to cyclopamine.

Quint E, Smith A, Avaron F, Laforest L, Miles J, Gaffield W, Akimenko MA.

Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8713-8. Epub 2002 Jun 11.

14.

BMP and Ihh/PTHrP signaling interact to coordinate chondrocyte proliferation and differentiation.

Minina E, Wenzel HM, Kreschel C, Karp S, Gaffield W, McMahon AP, Vortkamp A.

Development. 2001 Nov;128(22):4523-34.

15.

Unique functions of Sonic hedgehog signaling during external genitalia development.

Haraguchi R, Mo R, Hui C, Motoyama J, Makino S, Shiroishi T, Gaffield W, Yamada G.

Development. 2001 Nov;128(21):4241-50.

16.

Prx1 and Prx2 are upstream regulators of sonic hedgehog and control cell proliferation during mandibular arch morphogenesis.

ten Berge D, Brouwer A, Korving J, Reijnen MJ, van Raaij EJ, Verbeek F, Gaffield W, Meijlink F.

Development. 2001 Aug;128(15):2929-38.

17.

Hedgehog-dependent oligodendrocyte lineage specification in the telencephalon.

Tekki-Kessaris N, Woodruff R, Hall AC, Gaffield W, Kimura S, Stiles CD, Rowitch DH, Richardson WD.

Development. 2001 Jul;128(13):2545-54.

18.

Inhibitory effect of steroidal alkaloids on drug transport and multidrug resistance in human cancer cells.

Lavie Y, Harel-Orbital T, Gaffield W, Liscovitch M.

Anticancer Res. 2001 Mar-Apr;21(2A):1189-94.

PMID:
11396162
19.

Cyclopamine inhibition of Sonic hedgehog signal transduction is not mediated through effects on cholesterol transport.

Incardona JP, Gaffield W, Lange Y, Cooney A, Pentchev PG, Liu S, Watson JA, Kapur RP, Roelink H.

Dev Biol. 2000 Aug 15;224(2):440-52.

20.

Transient establishment of anteroposterior polarity in the zebrafish pectoral fin bud in the absence of sonic hedgehog activity.

Neumann CJ, Grandel H, Gaffield W, Schulte-Merker S, Nüsslein-Volhard C.

Development. 1999 Nov;126(21):4817-26.

21.

A looking glass perspective: thalidomide and cyclopamine.

Gaffield W, Incardona JP, Kapur RP, Roelink H.

Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):579-88. Review.

PMID:
10512190
22.

Essential role for Sonic hedgehog during hair follicle morphogenesis.

Chiang C, Swan RZ, Grachtchouk M, Bolinger M, Litingtung Y, Robertson EK, Cooper MK, Gaffield W, Westphal H, Beachy PA, Dlugosz AA.

Dev Biol. 1999 Jan 1;205(1):1-9.

23.

The teratogenic Veratrum alkaloid cyclopamine inhibits sonic hedgehog signal transduction.

Incardona JP, Gaffield W, Kapur RP, Roelink H.

Development. 1998 Sep;125(18):3553-62.

24.

Induction of terata in hamsters by solanidane alkaloids derived from Solanum tuberosum.

Gaffield W, Keeler RF.

Chem Res Toxicol. 1996 Mar;9(2):426-33.

PMID:
8839045
25.

Implication of C-5, C-6 unsaturation as a key structural factor in steroidal alkaloid-induced mammalian teratogenesis.

Gaffield W, Keeler RF.

Experientia. 1993 Oct 15;49(10):922-4. No abstract available.

PMID:
8224110
26.

Viewing stereopictures in three dimensions with naked eyes.

McKeon TA, Gaffield W.

Trends Biochem Sci. 1990 Nov;15(11):412-3. Review. No abstract available.

PMID:
2278097
27.

Spirosolane-containing Solanum species and induction of congenital craniofacial malformations.

Keeler RF, Baker DC, Gaffield W.

Toxicon. 1990;28(8):873-84. Review.

PMID:
2080514
28.

Pathology in hamsters administered Solanum plant species that contain steroidal alkaloids.

Baker DC, Keeler RF, Gaffield W.

Toxicon. 1989;27(12):1331-7.

PMID:
2629175
29.

Lesions of potato sprout and extracted potato sprout alkaloid toxicity in Syrian hamsters.

Baker D, Keeler R, Gaffield W.

J Toxicol Clin Toxicol. 1987;25(3):199-208.

PMID:
3612898
30.

Structure and stereochemistry of steroidal amine teratogens.

Gaffield W, Keeler RF.

Adv Exp Med Biol. 1984;177:241-51. Review.

PMID:
6388262
31.
33.

Chemical ionization-mass spectrometry of nitrosamines.

Gaffield W, Fish RH, Holmstead RL, Poppiti J, Yergey AL.

IARC Sci Publ. 1976;(14):11-20. No abstract available.

PMID:
1002193
34.

Activation of glutaraldehyde-crosslinked chymotrypsinogen-A. Enzymatic activity and circular dichroism studies.

Gaffield W, Tomimatsu Y, Olson AC, Jansen EF.

Arch Biochem Biophys. 1973 Aug;157(2):405-14. No abstract available.

PMID:
4199857
35.

Circular dichroism and optical rotatory dispersion of alpha-gliadin.

Kasarda DD, Bernardin JE, Gaffield W.

Biochemistry. 1968 Nov;7(11):3950-7. No abstract available.

PMID:
5722264
36.

Rotatory dispersion studies. V. The cinchona alkaloids.

Lyle GG, Gaffield W.

Tetrahedron. 1967 Jan;23(1):51-63. No abstract available.

PMID:
6037291
37.

Optical rotatory dispersion of egg proteins. II. Environment sensitive side chain chromophores in conalbumin.

Gaffield W, Vitello L, Tomimatsu Y.

Biochem Biophys Res Commun. 1966 Oct 5;25(1):35-42. No abstract available.

PMID:
5971756
38.

SYNTHESIS OF BETA-PHENYLSERINES.

WAWZONEK S, GAFFIELD WG.

J Med Chem. 1963 Jul;6:442-4. No abstract available.

PMID:
14184902

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