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Items: 1 to 50 of 60

1.

The versatility of the CD1 lipid antigen presentation pathway.

Chancellor A, Gadola SD, Mansour S.

Immunology. 2018 Jun;154(2):196-203. doi: 10.1111/imm.12912. Epub 2018 Mar 24. Review.

2.

The impact of rheumatologist-performed ultrasound on diagnosis and management of inflammatory arthritis in routine clinical practice.

Kelly S, Davidson B, Keidel S, Gadola S, Gorman C, Meenagh G, Reynolds P.

BMC Musculoskelet Disord. 2017 Nov 22;18(1):487. doi: 10.1186/s12891-017-1850-4.

3.

CD1b-restricted GEM T cell responses are modulated by Mycobacterium tuberculosis mycolic acid meromycolate chains.

Chancellor A, Tocheva AS, Cave-Ayland C, Tezera L, White A, Al Dulayymi JR, Bridgeman JS, Tews I, Wilson S, Lissin NM, Tebruegge M, Marshall B, Sharpe S, Elliott T, Skylaris CK, Essex JW, Baird MS, Gadola S, Elkington P, Mansour S.

Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):E10956-E10964. doi: 10.1073/pnas.1708252114. Epub 2017 Nov 20.

4.

Multitissue Transcriptomics Delineates the Diversity of Airway T Cell Functions in Asthma.

Singhania A, Wallington JC, Smith CG, Horowitz D, Staples KJ, Howarth PH, Gadola SD, Djukanović R, Woelk CH, Hinks TSC.

Am J Respir Cell Mol Biol. 2018 Feb;58(2):261-270. doi: 10.1165/rcmb.2017-0162OC.

5.

Quantitative and qualitative iNKT repertoire associations with disease susceptibility and outcome in macaque tuberculosis infection.

Chancellor A, White A, Tocheva AS, Fenn JR, Dennis M, Tezera L, Singhania A, Elliott T, Tebruegge M, Elkington P, Gadola S, Sharpe S, Mansour S.

Tuberculosis (Edinb). 2017 Jul;105:86-95. doi: 10.1016/j.tube.2017.04.011. Epub 2017 Apr 28.

6.

The Clonal Invariant NKT Cell Repertoire in People with Type 1 Diabetes Is Characterized by a Loss of Clones Expressing High-Affinity TCRs.

Tocheva AS, Mansour S, Holt TG, Jones S, Chancellor A, Sanderson JP, Eren E, Elliott TJ, Holt RI, Gadola SD.

J Immunol. 2017 Feb 15;198(4):1452-1459. doi: 10.4049/jimmunol.1600255. Epub 2017 Jan 6.

7.

Bone marrow transplantation for MHC class I deficiency corrects T-cell immunity but dissociates natural killer cell repertoire formation from function.

Gao Y, Arkwright PD, Carter R, Cazaly A, Harrison RJ, Mant A, Cant AJ, Gadola S, Elliott TJ, Khakoo SI, Williams AP.

J Allergy Clin Immunol. 2016 Dec;138(6):1733-1736.e2. doi: 10.1016/j.jaci.2016.06.029. Epub 2016 Jul 27. No abstract available.

8.

Cholesteryl esters stabilize human CD1c conformations for recognition by self-reactive T cells.

Mansour S, Tocheva AS, Cave-Ayland C, Machelett MM, Sander B, Lissin NM, Molloy PE, Baird MS, Stübs G, Schröder NW, Schumann RR, Rademann J, Postle AD, Jakobsen BK, Marshall BG, Gosain R, Elkington PT, Elliott T, Skylaris CK, Essex JW, Tews I, Gadola SD.

Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):E1266-75. doi: 10.1073/pnas.1519246113. Epub 2016 Feb 16.

9.

Structural and Functional Changes of the Invariant NKT Clonal Repertoire in Early Rheumatoid Arthritis.

Mansour S, Tocheva AS, Sanderson JP, Goulston LM, Platten H, Serhal L, Parsons C, Edwards MH, Woelk CH, Elkington PT, Elliott T, Cooper C, Edwards CJ, Gadola SD.

J Immunol. 2015 Dec 15;195(12):5582-91. doi: 10.4049/jimmunol.1501092. Epub 2015 Nov 9.

10.

Multidimensional endotypes of asthma: topological data analysis of cross-sectional clinical, pathological, and immunological data.

Hinks T, Zhou X, Staples K, Dimitrov B, Manta A, Petrossian T, Lum P, Smith C, Ward J, Howarth P, Walls A, Gadola SD, Djukanović R.

Lancet. 2015 Feb 26;385 Suppl 1:S42. doi: 10.1016/S0140-6736(15)60357-9.

PMID:
26312864
11.

Microcirculation in the foot is augmented by neuromuscular stimulation via the common peroneal nerve in different lower limb postures: a potential treatment for leg ulcers.

Warwick DJ, Shaikh A, Worsley P, Bain D, Gadola S, Tucker A, Gadola S, Stokes M.

Int Angiol. 2015 Jul 3. [Epub ahead of print]

PMID:
26138236
12.

T-cell populations in chronic pancreatitis.

Jupp J, Mansour S, Johnson CD, Sanderson J, Fine D, Gadola S.

Pancreatology. 2015 Jul-Aug;15(4):311-2. doi: 10.1016/j.pan.2015.04.009. Epub 2015 May 8. No abstract available.

PMID:
26003853
13.

Microcirculation in the foot is augmented by neuromuscular stimulation via the common peroneal nerve in different lower limb postures: a potential treatment for leg ulcers.

Warwick D, Shaikh A, Worsley P, Gadola S, Bain D, Tucker A, Gadola SD, Stokes M.

Int Angiol. 2015 Apr;34(2):158-65.

PMID:
25839841
14.

Innate and adaptive T cells in asthmatic patients: Relationship to severity and disease mechanisms.

Hinks TS, Zhou X, Staples KJ, Dimitrov BD, Manta A, Petrossian T, Lum PY, Smith CG, Ward JA, Howarth PH, Walls AF, Gadola SD, Djukanović R.

J Allergy Clin Immunol. 2015 Aug;136(2):323-33. doi: 10.1016/j.jaci.2015.01.014. Epub 2015 Mar 5.

15.

Reply: To PMID 24582167.

Gao Y, Gadola S, Grimbacher B, Williams AP.

J Allergy Clin Immunol. 2014 Oct;134(4):990. doi: 10.1016/j.jaci.2014.06.040. Epub 2014 Aug 23. No abstract available.

PMID:
25159467
16.

Common variable immunodeficiency is associated with a functional deficiency of invariant natural killer T cells.

Gao Y, Workman S, Gadola S, Elliott T, Grimbacher B, Williams AP.

J Allergy Clin Immunol. 2014 May;133(5):1420-8, 1428.e1. doi: 10.1016/j.jaci.2013.10.059. Epub 2014 Feb 26.

PMID:
24582167
17.

NK cell killer Ig-like receptor repertoire acquisition and maturation are strongly modulated by HLA class I molecules.

Sleiman M, Brons NH, Kaoma T, Dogu F, Villa-Forte A, Lenoble P, Hentges F, Kotsch K, Gadola SD, Vilches C, Zimmer J.

J Immunol. 2014 Mar 15;192(6):2602-10. doi: 10.4049/jimmunol.1302843. Epub 2014 Feb 19.

18.

Neuromuscular electrostimulation viathe common peroneal nerve promotes lower limb blood flow in a below-kneecast: A potential for thromboprophylaxis.

Warwick DJ, Shaikh A, Gadola S, Stokes M, Worsley P, Bain D, Tucker AT, Gadola SD.

Bone Joint Res. 2013 Sep 2;2(9):179-85. doi: 10.1302/2046-3758.29.2000176. Print 2013.

19.

CD1d protein structure determines species-selective antigenicity of isoglobotrihexosylceramide (iGb3) to invariant NKT cells.

Sanderson JP, Brennan PJ, Mansour S, Matulis G, Patel O, Lissin N, Godfrey DI, Kawahara K, Zähringer U, Rossjohn J, Brenner MB, Gadola SD.

Eur J Immunol. 2013 Mar;43(3):815-25. doi: 10.1002/eji.201242952. Epub 2013 Jan 31.

20.

Intestinal ischaemia and mesenteric necrosis in a heavy smoker.

Darshan J, Shaw E, Green B, Gallagher PJ, Gadola SD.

QJM. 2013 Feb;106(2):183-6. doi: 10.1093/qjmed/hcs178. Epub 2012 Oct 12. No abstract available.

PMID:
23064830
21.

Motor control retraining exercises for shoulder impingement: effects on function, muscle activation, and biomechanics in young adults.

Worsley P, Warner M, Mottram S, Gadola S, Veeger HE, Hermens H, Morrissey D, Little P, Cooper C, Carr A, Stokes M.

J Shoulder Elbow Surg. 2013 Apr;22(4):e11-9. doi: 10.1016/j.jse.2012.06.010. Epub 2012 Sep 1.

22.

Clinical and immunological remarks about TAP deficiency.

Zimmer J, Sleiman M, Hentges F, Gadola SD.

J Biol Chem. 2012 Aug 3;287(32):27047; author reply 27048. doi: 10.1074/jbc.L112.379578. No abstract available.

23.

Perspectives: modelling the vasculitis and granulomatous tissue destruction of granulomatosis with polyangiitis (GPA).

Gadola SD.

Clin Exp Rheumatol. 2012 Jan-Feb;30(1 Suppl 70):S1-2. Epub 2012 May 10. No abstract available.

PMID:
22640646
24.

Vasculitis in 2011: the renaissance of granulomatous inflammation in AAV.

Gadola SD, Gross WL.

Nat Rev Rheumatol. 2012 Jan 10;8(2):74-6. doi: 10.1038/nrrheum.2011.218. Review.

PMID:
22231230
25.

Invariant natural killer T cells recognize lipid self antigen induced by microbial danger signals.

Brennan PJ, Tatituri RV, Brigl M, Kim EY, Tuli A, Sanderson JP, Gadola SD, Hsu FF, Besra GS, Brenner MB.

Nat Immunol. 2011 Oct 30;12(12):1202-11. doi: 10.1038/ni.2143.

26.

Natural variations at position 93 of the invariant Vα24-Jα18 α chain of human iNKT-cell TCRs strongly impact on CD1d binding.

Sanderson JP, Waldburger-Hauri K, Garzón D, Matulis G, Mansour S, Pumphrey NJ, Lissin N, Villiger PM, Jakobsen B, Faraldo-Gómez JD, Gadola SD.

Eur J Immunol. 2012 Jan;42(1):248-55. doi: 10.1002/eji.201141956. Epub 2011 Nov 28.

27.

Innate-like control of human iNKT cell autoreactivity via the hypervariable CDR3beta loop.

Matulis G, Sanderson JP, Lissin NM, Asparuhova MB, Bommineni GR, Schümperli D, Schmidt RR, Villiger PM, Jakobsen BK, Gadola SD.

PLoS Biol. 2010 Jun 22;8(6):e1000402. doi: 10.1371/journal.pbio.1000402.

28.

Expression of CD1d and presence of invariant NKT cells in classical Hodgkin lymphoma.

Xu C, de Vries R, Visser L, Diepstra A, Gadola SD, Poppema S, van den Berg A.

Am J Hematol. 2010 Jul;85(7):539-41. doi: 10.1002/ajh.21743. No abstract available.

29.

Nasal carriage of Staphylococcus aureus and endonasal activity in Wegener s granulomatosis as compared to rheumatoid arthritis and chronic Rhinosinusitis with nasal polyps.

Laudien M, Gadola SD, Podschun R, Hedderich J, Paulsen J, Reinhold-Keller E, Csernok E, Ambrosch P, Hellmich B, Moosig F, Gross WL, Sahly H, Lamprecht P.

Clin Exp Rheumatol. 2010 Jan-Feb;28(1 Suppl 57):51-5.

PMID:
20412703
30.

[Interleukin-1 cytokines, inflammasomes, NOD-signalosomes and autoinflammation].

Gadola SD.

Z Rheumatol. 2009 Nov;68(9):712-9. doi: 10.1007/s00393-009-0488-5. German.

PMID:
19830437
31.

Anti-TNF-induced lupus.

Williams EL, Gadola S, Edwards CJ.

Rheumatology (Oxford). 2009 Jul;48(7):716-20. doi: 10.1093/rheumatology/kep080. Epub 2009 May 4. Review.

PMID:
19416947
32.

Virus infection, asthma, and chronic obstructive pulmonary disease.

Djukanovic R, Gadola SD.

N Engl J Med. 2008 Nov 6;359(19):2062-4. doi: 10.1056/NEJMcibr0806978. No abstract available.

PMID:
18987374
33.

TAP deficiency syndrome: chronic rhinosinusitis and conductive hearing loss.

Caversaccio M, Bonél HM, Carter R, Williams AP, Gadola SD.

Eur Arch Otorhinolaryngol. 2008 Oct;265(10):1289-92. doi: 10.1007/s00405-008-0610-3. Epub 2008 Feb 19.

34.

Evidence that anti-muscarinic antibodies in Sjögren's syndrome recognise both M3R and M1R.

Schegg V, Vogel M, Didichenko S, Stadler MB, Beleznay Z, Gadola S, Sengupta C, Stadler BM, Miescher SM.

Biologicals. 2008 Jul;36(4):213-22. doi: 10.1016/j.biologicals.2007.11.001. Epub 2008 Jan 14.

PMID:
18249005
35.

Facets of lupus erythematosus: panniculitis responding to thalidomide.

Wienert S, Gadola S, Hunziker T.

J Dtsch Dermatol Ges. 2008 Mar;6(3):214-6. Epub 2007 Dec 11. English, German.

PMID:
18076656
36.

Pregnancy induces numerical and functional changes of CD4+CD25 high regulatory T cells in patients with rheumatoid arthritis.

Förger F, Marcoli N, Gadola S, Möller B, Villiger PM, Østensen M.

Ann Rheum Dis. 2008 Jul;67(7):984-90. Epub 2007 Oct 30.

PMID:
17971458
37.
38.

Invariant natural killer T cells in asthma and chronic obstructive pulmonary disease.

Vijayanand P, Seumois G, Pickard C, Powell RM, Angco G, Sammut D, Gadola SD, Friedmann PS, Djukanovic R.

N Engl J Med. 2007 Apr 5;356(14):1410-22.

39.

Impaired selection of invariant natural killer T cells in diverse mouse models of glycosphingolipid lysosomal storage diseases.

Gadola SD, Silk JD, Jeans A, Illarionov PA, Salio M, Besra GS, Dwek R, Butters TD, Platt FM, Cerundolo V.

J Exp Med. 2006 Oct 2;203(10):2293-303. Epub 2006 Sep 18.

40.

Structure and binding kinetics of three different human CD1d-alpha-galactosylceramide-specific T cell receptors.

Gadola SD, Koch M, Marles-Wright J, Lissin NM, Shepherd D, Matulis G, Harlos K, Villiger PM, Stuart DI, Jakobsen BK, Cerundolo V, Jones EY.

J Exp Med. 2006 Mar 20;203(3):699-710. Epub 2006 Mar 6.

41.

Report of the roundtable discussion organised by the Swiss Proteomics Society (SPS), Bern, 8th December 2004.

Noukakis D, Gadola S, Stöcklin R.

Proteomics. 2005 Aug;5(12):3017-8.

PMID:
16021608
42.

The crystal structure of human CD1d with and without alpha-galactosylceramide.

Koch M, Stronge VS, Shepherd D, Gadola SD, Mathew B, Ritter G, Fersht AR, Besra GS, Schmidt RR, Jones EY, Cerundolo V.

Nat Immunol. 2005 Aug;6(8):819-26. Epub 2005 Jul 10.

PMID:
16007090
44.

[Adult-onset primary immunodeficiencies].

Gadola S, Salzer U, Schultz H, Grimbacher B.

Internist (Berl). 2004 Aug;45(8):912-22. German.

PMID:
15241502
45.

The crystal structure of human CD1b with a bound bacterial glycolipid.

Batuwangala T, Shepherd D, Gadola SD, Gibson KJ, Zaccai NR, Fersht AR, Besra GS, Cerundolo V, Jones EY.

J Immunol. 2004 Feb 15;172(4):2382-8.

46.

The mechanisms controlling NK cell autoreactivity in TAP2-deficient patients.

Markel G, Mussaffi H, Ling KL, Salio M, Gadola S, Steuer G, Blau H, Achdout H, de Miguel M, Gonen-Gross T, Hanna J, Arnon TI, Qimron U, Volovitz I, Eisenbach L, Blumberg RS, Porgador A, Cerundolo V, Mandelboim O.

Blood. 2004 Mar 1;103(5):1770-8. Epub 2003 Nov 6. Erratum in: Blood. 2015 Mar 19;125(12):2006.

47.

Immunoregulatory role of CD1d in the hydrocarbon oil-induced model of lupus nephritis.

Yang JQ, Singh AK, Wilson MT, Satoh M, Stanic AK, Park JJ, Hong S, Gadola SD, Mizutani A, Kakumanu SR, Reeves WH, Cerundolo V, Joyce S, Van Kaer L, Singh RR.

J Immunol. 2003 Aug 15;171(4):2142-53.

48.
49.

Generation of CD1 tetramers as a tool to monitor glycolipid-specific T cells.

Gadola SD, Karadimitris A, Zaccai NR, Salio M, Dulphy N, Shepherd D, Jones EY, Cerundolo V.

Philos Trans R Soc Lond B Biol Sci. 2003 May 29;358(1433):875-7. Review.

50.

Identification of a TAP-independent, immunoproteasome-dependent CD8+ T-cell epitope in Epstein-Barr virus latent membrane protein 2.

Lautscham G, Haigh T, Mayrhofer S, Taylor G, Croom-Carter D, Leese A, Gadola S, Cerundolo V, Rickinson A, Blake N.

J Virol. 2003 Feb;77(4):2757-61.

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