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Items: 1 to 50 of 58

1.

Raman microspectroscopy differentiates perinatal pathogens on ex vivo infected human fetal membrane tissues.

Ayala OD, Doster RS, Manning SD, O'Brien CM, Aronoff DM, Gaddy JA, Mahadevan-Jansen A.

J Biophotonics. 2019 Jun 4:e201800449. doi: 10.1002/jbio.201800449. [Epub ahead of print]

PMID:
31162821
2.

Protein kinase D mediates inflammatory responses of human placental macrophages to Group B Streptococcus.

Sutton JA, Rogers LM, Dixon BREA, Kirk L, Doster R, Algood HM, Gaddy JA, Flaherty R, Manning SD, Aronoff DM.

Am J Reprod Immunol. 2019 Mar;81(3):e13075. doi: 10.1111/aji.13075. Epub 2019 Jan 30.

PMID:
30582878
3.

Investigation of the Role That NADH Peroxidase Plays in Oxidative Stress Survival in Group B Streptococcus.

Korir ML, Flaherty RA, Rogers LM, Gaddy JA, Aronoff DM, Manning SD.

Front Microbiol. 2018 Nov 20;9:2786. doi: 10.3389/fmicb.2018.02786. eCollection 2018.

4.

Streptococcus agalactiae Induces Placental Macrophages To Release Extracellular Traps Loaded with Tissue Remodeling Enzymes via an Oxidative Burst-Dependent Mechanism.

Doster RS, Sutton JA, Rogers LM, Aronoff DM, Gaddy JA.

MBio. 2018 Nov 20;9(6). pii: e02084-18. doi: 10.1128/mBio.02084-18.

5.

ArsRS-Dependent Regulation of homB Contributes to Helicobacter pylori Biofilm Formation.

Servetas SL, Doster RS, Kim A, Windham IH, Cha JH, Gaddy JA, Merrell DS.

Front Microbiol. 2018 Aug 2;9:1497. doi: 10.3389/fmicb.2018.01497. eCollection 2018.

6.

Decidual stromal cell-derived PGE2 regulates macrophage responses to microbial threat.

Rogers LM, Anders AP, Doster RS, Gill EA, Gnecco JS, Holley JM, Randis TM, Ratner AJ, Gaddy JA, Osteen K, Aronoff DM.

Am J Reprod Immunol. 2018 Oct;80(4):e13032. doi: 10.1111/aji.13032. Epub 2018 Aug 7.

PMID:
30084522
7.

Human Milk Oligosaccharides (HMOs) Sensitize Group B Streptococcus to Clindamycin, Erythromycin, Gentamicin, and Minocycline on a Strain Specific Basis.

Craft KM, Gaddy JA, Townsend SD.

ACS Chem Biol. 2018 Aug 17;13(8):2020-2026. doi: 10.1021/acschembio.8b00661. Epub 2018 Aug 6.

PMID:
30071726
9.

Drug-Resistant Staphylococcus aureus Strains Reveal Distinct Biochemical Features with Raman Microspectroscopy.

Ayala OD, Wakeman CA, Pence IJ, Gaddy JA, Slaughter JC, Skaar EP, Mahadevan-Jansen A.

ACS Infect Dis. 2018 Aug 10;4(8):1197-1210. doi: 10.1021/acsinfecdis.8b00029. Epub 2018 Jun 25.

PMID:
29845863
10.

CagY-Dependent Regulation of Type IV Secretion in Helicobacter pylori Is Associated with Alterations in Integrin Binding.

Skoog EC, Morikis VA, Martin ME, Foster GA, Cai LP, Hansen LM, Li B, Gaddy JA, Simon SI, Solnick JV.

MBio. 2018 May 15;9(3). pii: e00717-18. doi: 10.1128/mBio.00717-18.

11.

The Host Antimicrobial Protein Calgranulin C Participates in the Control of Campylobacter jejuni Growth via Zinc Sequestration.

Shank JM, Kelley BR, Jackson JW, Tweedie JL, Franklin D, Damo SM, Gaddy JA, Murphy CN, Johnson JG.

Infect Immun. 2018 May 22;86(6). pii: e00234-18. doi: 10.1128/IAI.00234-18. Print 2018 Jun.

12.

Antimicrobial and Antibiofilm Activity of Human Milk Oligosaccharides against Streptococcus agalactiae, Staphylococcus aureus, and Acinetobacter baumannii.

Ackerman DL, Craft KM, Doster RS, Weitkamp JH, Aronoff DM, Gaddy JA, Townsend SD.

ACS Infect Dis. 2018 Mar 9;4(3):315-324. doi: 10.1021/acsinfecdis.7b00183. Epub 2017 Dec 8.

13.

Macrophage Extracellular Traps: A Scoping Review.

Doster RS, Rogers LM, Gaddy JA, Aronoff DM.

J Innate Immun. 2018;10(1):3-13. doi: 10.1159/000480373. Epub 2017 Oct 7. Review.

14.

Human Milk Oligosaccharides Exhibit Antimicrobial and Antibiofilm Properties against Group B Streptococcus.

Ackerman DL, Doster RS, Weitkamp JH, Aronoff DM, Gaddy JA, Townsend SD.

ACS Infect Dis. 2017 Aug 11;3(8):595-605. doi: 10.1021/acsinfecdis.7b00064. Epub 2017 Jun 13.

15.

Expression, Purification, and Antimicrobial Activity of S100A12.

Jackson E, Little S, Franklin DS, Gaddy JA, Damo SM.

J Vis Exp. 2017 May 13;(123). doi: 10.3791/55557.

16.

Group B Streptococcus Induces Neutrophil Recruitment to Gestational Tissues and Elaboration of Extracellular Traps and Nutritional Immunity.

Kothary V, Doster RS, Rogers LM, Kirk LA, Boyd KL, Romano-Keeler J, Haley KP, Manning SD, Aronoff DM, Gaddy JA.

Front Cell Infect Microbiol. 2017 Feb 3;7:19. doi: 10.3389/fcimb.2017.00019. eCollection 2017.

17.

Current concepts in maternal-fetal immunology: Recognition and response to microbial pathogens by decidual stromal cells.

Anders AP, Gaddy JA, Doster RS, Aronoff DM.

Am J Reprod Immunol. 2017 Mar;77(3). doi: 10.1111/aji.12623. Epub 2017 Jan 3. Review.

18.

The PAS Domain-Containing Protein HeuR Regulates Heme Uptake in Campylobacter jejuni.

Johnson JG, Gaddy JA, DiRita VJ.

MBio. 2016 Nov 15;7(6). pii: e01691-16. doi: 10.1128/mBio.01691-16.

19.

Idiopathic subglottic stenosis is associated with activation of the inflammatory IL-17A/IL-23 axis.

Gelbard A, Katsantonis NG, Mizuta M, Newcomb D, Rotsinger J, Rousseau B, Daniero JJ, Edell ES, Ekbom DC, Kasperbauer JL, Hillel AT, Yang L, Garrett CG, Netterville JL, Wootten CT, Francis DO, Stratton C, Jenkins K, McGregor TL, Gaddy JA, Blackwell TS, Drake WP.

Laryngoscope. 2016 Nov;126(11):E356-E361. doi: 10.1002/lary.26098. Epub 2016 Jun 14.

20.

Nutrition and Helicobacter pylori: Host Diet and Nutritional Immunity Influence Bacterial Virulence and Disease Outcome.

Haley KP, Gaddy JA.

Gastroenterol Res Pract. 2016;2016:3019362. doi: 10.1155/2016/3019362. Epub 2016 Sep 5. Review.

21.

Clinical investigation of biofilm in non-healing wounds by high resolution microscopy techniques.

Hurlow J, Blanz E, Gaddy JA.

J Wound Care. 2016 Sep;25 Suppl 9:S11-22. doi: 10.12968/jowc.2016.25.Sup9.S11.

22.

Staphylococcus aureus Infection of Human Gestational Membranes Induces Bacterial Biofilm Formation and Host Production of Cytokines.

Doster RS, Kirk LA, Tetz LM, Rogers LM, Aronoff DM, Gaddy JA.

J Infect Dis. 2017 Feb 15;215(4):653-657. doi: 10.1093/infdis/jiw300.

23.

Characterization of Key Helicobacter pylori Regulators Identifies a Role for ArsRS in Biofilm Formation.

Servetas SL, Carpenter BM, Haley KP, Gilbreath JJ, Gaddy JA, Merrell DS.

J Bacteriol. 2016 Aug 25;198(18):2536-48. doi: 10.1128/JB.00324-16. Print 2016 Sep 15.

24.

The innate immune protein calprotectin promotes Pseudomonas aeruginosa and Staphylococcus aureus interaction.

Wakeman CA, Moore JL, Noto MJ, Zhang Y, Singleton MD, Prentice BM, Gilston BA, Doster RS, Gaddy JA, Chazin WJ, Caprioli RM, Skaar EP.

Nat Commun. 2016 Jun 15;7:11951. doi: 10.1038/ncomms11951.

25.

Molecular analysis of idiopathic subglottic stenosis for Mycobacterium species.

Gelbard A, Katsantonis NG, Mizuta M, Newcomb D, Rotsinger J, Rousseau B, Daniero JJ, Edell ES, Ekbom DC, Kasperbauer JL, Hillel AT, Yang L, Garrett CG, Netterville JL, Wootten CT, Francis DO, Stratton C, Jenkins K, McGregor TL, Gaddy JA, Blackwell TS, Drake WP.

Laryngoscope. 2017 Jan;127(1):179-185. doi: 10.1002/lary.26097. Epub 2016 Jun 14.

26.

Association between genotypic diversity and biofilm production in group B Streptococcus.

Parker RE, Laut C, Gaddy JA, Zadoks RN, Davies HD, Manning SD.

BMC Microbiol. 2016 May 20;16:86. doi: 10.1186/s12866-016-0704-9.

27.

Peptidomimetic Small Molecules Disrupt Type IV Secretion System Activity in Diverse Bacterial Pathogens.

Shaffer CL, Good JA, Kumar S, Krishnan KS, Gaddy JA, Loh JT, Chappell J, Almqvist F, Cover TL, Hadjifrangiskou M.

MBio. 2016 Apr 26;7(2):e00221-16. doi: 10.1128/mBio.00221-16.

28.

Helicobacter pylori Resists the Antimicrobial Activity of Calprotectin via Lipid A Modification and Associated Biofilm Formation.

Gaddy JA, Radin JN, Cullen TW, Chazin WJ, Skaar EP, Trent MS, Algood HM.

MBio. 2015 Dec 8;6(6):e01349-15. doi: 10.1128/mBio.01349-15.

29.

Highly differentiated human airway epithelial cells: a model to study host cell-parasite interactions in pertussis.

Guevara C, Zhang C, Gaddy JA, Iqbal J, Guerra J, Greenberg DP, Decker MD, Carbonetti N, Starner TD, McCray PB Jr, Mooi FR, Gómez-Duarte OG.

Infect Dis (Lond). 2016;48(3):177-88. doi: 10.3109/23744235.2015.1100323. Epub 2015 Oct 22.

30.

Helicobacter pylori adaptation in vivo in response to a high-salt diet.

Loh JT, Gaddy JA, Algood HM, Gaudieri S, Mallal S, Cover TL.

Infect Immun. 2015 Dec;83(12):4871-83. doi: 10.1128/IAI.00918-15. Epub 2015 Oct 5.

31.

Metalloregulation of Helicobacter pylori physiology and pathogenesis.

Haley KP, Gaddy JA.

Front Microbiol. 2015 Sep 2;6:911. doi: 10.3389/fmicb.2015.00911. eCollection 2015. Review.

32.

The Human Antimicrobial Protein Calgranulin C Participates in Control of Helicobacter pylori Growth and Regulation of Virulence.

Haley KP, Delgado AG, Piazuelo MB, Mortensen BL, Correa P, Damo SM, Chazin WJ, Skaar EP, Gaddy JA.

Infect Immun. 2015 Jul;83(7):2944-56. doi: 10.1128/IAI.00544-15. Epub 2015 May 11.

33.

Helicobacter pylori: Genomic Insight into the Host-Pathogen Interaction.

Haley KP, Gaddy JA.

Int J Genomics. 2015;2015:386905. doi: 10.1155/2015/386905. Epub 2015 Feb 5. Review.

34.

Regulation of Helicobacter pylori Virulence Within the Context of Iron Deficiency.

Noto JM, Lee JY, Gaddy JA, Cover TL, Amieva MR, Peek RM Jr.

J Infect Dis. 2015 Jun 1;211(11):1790-4. doi: 10.1093/infdis/jiu805. Epub 2014 Dec 11.

35.
36.

The host protein calprotectin modulates the Helicobacter pylori cag type IV secretion system via zinc sequestration.

Gaddy JA, Radin JN, Loh JT, Piazuelo MB, Kehl-Fie TE, Delgado AG, Ilca FT, Peek RM, Cover TL, Chazin WJ, Skaar EP, Scott Algood HM.

PLoS Pathog. 2014 Oct 16;10(10):e1004450. doi: 10.1371/journal.ppat.1004450. eCollection 2014 Oct.

37.

Insights into reference point indentation involving human cortical bone: sensitivity to tissue anisotropy and mechanical behavior.

Granke M, Coulmier A, Uppuganti S, Gaddy JA, Does MD, Nyman JS.

J Mech Behav Biomed Mater. 2014 Sep;37:174-85. doi: 10.1016/j.jmbbm.2014.05.016. Epub 2014 May 27.

38.

Genes required for assembly of pili associated with the Helicobacter pylori cag type IV secretion system.

Johnson EM, Gaddy JA, Voss BJ, Hennig EE, Cover TL.

Infect Immun. 2014 Aug;82(8):3457-70. doi: 10.1128/IAI.01640-14. Epub 2014 Jun 2.

39.

Analysis of surface-exposed outer membrane proteins in Helicobacter pylori.

Voss BJ, Gaddy JA, McDonald WH, Cover TL.

J Bacteriol. 2014 Jul;196(13):2455-71. doi: 10.1128/JB.01768-14. Epub 2014 Apr 25.

40.

Role of connexin 43 in Helicobacter pylori VacA-induced cell death.

Radin JN, González-Rivera C, Frick-Cheng AE, Sheng J, Gaddy JA, Rubin DH, Algood HM, McClain MS, Cover TL.

Infect Immun. 2014 Jan;82(1):423-32. doi: 10.1128/IAI.00827-13. Epub 2013 Nov 4.

41.

Control of gene expression in Helicobacter pylori using the Tet repressor.

McClain MS, Duncan SS, Gaddy JA, Cover TL.

J Microbiol Methods. 2013 Dec;95(3):336-41. doi: 10.1016/j.mimet.2013.09.019. Epub 2013 Oct 8.

42.

Impaired autophagy, defective T cell homeostasis, and a wasting syndrome in mice with a T cell-specific deletion of Vps34.

Parekh VV, Wu L, Boyd KL, Williams JA, Gaddy JA, Olivares-Villagómez D, Cover TL, Zong WX, Zhang J, Van Kaer L.

J Immunol. 2013 May 15;190(10):5086-101. doi: 10.4049/jimmunol.1202071. Epub 2013 Apr 17.

43.

Flagellar localization of a Helicobacter pylori autotransporter protein.

Radin JN, Gaddy JA, González-Rivera C, Loh JT, Algood HM, Cover TL.

MBio. 2013 Apr 9;4(2):e00613-12. doi: 10.1128/mBio.00613-12.

44.

High dietary salt intake exacerbates Helicobacter pylori-induced gastric carcinogenesis.

Gaddy JA, Radin JN, Loh JT, Zhang F, Washington MK, Peek RM Jr, Algood HM, Cover TL.

Infect Immun. 2013 Jun;81(6):2258-67. doi: 10.1128/IAI.01271-12. Epub 2013 Apr 8.

45.

Functional plasticity in the type IV secretion system of Helicobacter pylori.

Barrozo RM, Cooke CL, Hansen LM, Lam AM, Gaddy JA, Johnson EM, Cariaga TA, Suarez G, Peek RM Jr, Cover TL, Solnick JV.

PLoS Pathog. 2013 Feb;9(2):e1003189. doi: 10.1371/journal.ppat.1003189. Epub 2013 Feb 28.

46.

Effect of ethanol on differential protein production and expression of potential virulence functions in the opportunistic pathogen Acinetobacter baumannii.

Nwugo CC, Arivett BA, Zimbler DL, Gaddy JA, Richards AM, Actis LA.

PLoS One. 2012;7(12):e51936. doi: 10.1371/journal.pone.0051936. Epub 2012 Dec 20.

47.

Iron deficiency accelerates Helicobacter pylori-induced carcinogenesis in rodents and humans.

Noto JM, Gaddy JA, Lee JY, Piazuelo MB, Friedman DB, Colvin DC, Romero-Gallo J, Suarez G, Loh J, Slaughter JC, Tan S, Morgan DR, Wilson KT, Bravo LE, Correa P, Cover TL, Amieva MR, Peek RM Jr.

J Clin Invest. 2013 Jan;123(1):479-92. doi: 10.1172/JCI64373. Epub 2012 Dec 21.

48.

Alterations in Helicobacter pylori triggered by contact with gastric epithelial cells.

Johnson EM, Gaddy JA, Cover TL.

Front Cell Infect Microbiol. 2012 Feb 28;2:17. doi: 10.3389/fcimb.2012.00017. eCollection 2012. Review.

49.

Role of acinetobactin-mediated iron acquisition functions in the interaction of Acinetobacter baumannii strain ATCC 19606T with human lung epithelial cells, Galleria mellonella caterpillars, and mice.

Gaddy JA, Arivett BA, McConnell MJ, López-Rojas R, Pachón J, Actis LA.

Infect Immun. 2012 Mar;80(3):1015-24. doi: 10.1128/IAI.06279-11. Epub 2012 Jan 9.

50.

Helicobacter pylori exploits a unique repertoire of type IV secretion system components for pilus assembly at the bacteria-host cell interface.

Shaffer CL, Gaddy JA, Loh JT, Johnson EM, Hill S, Hennig EE, McClain MS, McDonald WH, Cover TL.

PLoS Pathog. 2011 Sep;7(9):e1002237. doi: 10.1371/journal.ppat.1002237. Epub 2011 Sep 1.

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