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Items: 1 to 50 of 63

1.

Microbiota and the clock: sexual dimorphism matters!

Weger BD, Gachon F.

Aging (Albany NY). 2019 Jun 20. doi: 10.18632/aging.102051. [Epub ahead of print] No abstract available.

2.

Chronotype: Implications for Epidemiologic Studies on Chrono-Nutrition and Cardiometabolic Health.

Almoosawi S, Vingeliene S, Gachon F, Voortman T, Palla L, Johnston JD, Van Dam RM, Darimont C, Karagounis LG.

Adv Nutr. 2019 Jan 1;10(1):30-42. doi: 10.1093/advances/nmy070.

3.

Cross-regulatory circuits linking inflammation, high-fat diet, and the circadian clock.

Gachon F, Yeung J, Naef F.

Genes Dev. 2018 Nov 1;32(21-22):1359-1360. doi: 10.1101/gad.320911.118. Review.

4.

The Mouse Microbiome Is Required for Sex-Specific Diurnal Rhythms of Gene Expression and Metabolism.

Weger BD, Gobet C, Yeung J, Martin E, Jimenez S, Betrisey B, Foata F, Berger B, Balvay A, Foussier A, Charpagne A, Boizet-Bonhoure B, Chou CJ, Naef F, Gachon F.

Cell Metab. 2019 Feb 5;29(2):362-382.e8. doi: 10.1016/j.cmet.2018.09.023. Epub 2018 Oct 18.

5.

Transcriptomic analyses reveal rhythmic and CLOCK-driven pathways in human skeletal muscle.

Perrin L, Loizides-Mangold U, Chanon S, Gobet C, Hulo N, Isenegger L, Weger BD, Migliavacca E, Charpagne A, Betts JA, Walhin JP, Templeman I, Stokes K, Thompson D, Tsintzas K, Robert M, Howald C, Riezman H, Feige JN, Karagounis LG, Johnston JD, Dermitzakis ET, Gachon F, Lefai E, Dibner C.

Elife. 2018 Apr 16;7. pii: e34114. doi: 10.7554/eLife.34114.

6.

Clock-dependent chromatin topology modulates circadian transcription and behavior.

Mermet J, Yeung J, Hurni C, Mauvoisin D, Gustafson K, Jouffe C, Nicolas D, Emmenegger Y, Gobet C, Franken P, Gachon F, Naef F.

Genes Dev. 2018 Mar 1;32(5-6):347-358. doi: 10.1101/gad.312397.118. Epub 2018 Mar 23.

7.

[Circadian proteomics].

Gachon F.

Biol Aujourdhui. 2018;212(3-4):55-59. doi: 10.1051/jbio/2018025. Epub 2019 Apr 11. French.

PMID:
30973132
8.

Transcription factor activity rhythms and tissue-specific chromatin interactions explain circadian gene expression across organs.

Yeung J, Mermet J, Jouffe C, Marquis J, Charpagne A, Gachon F, Naef F.

Genome Res. 2018 Feb;28(2):182-191. doi: 10.1101/gr.222430.117. Epub 2017 Dec 18.

9.

Diurnal liver mass is associated with ribosome biogenesis.

Sinturel F, Gachon F.

Oncotarget. 2017 Nov 1;8(57):96476-96477. doi: 10.18632/oncotarget.22255. eCollection 2017 Nov 14. No abstract available.

10.

Guidelines for Genome-Scale Analysis of Biological Rhythms.

Hughes ME, Abruzzi KC, Allada R, Anafi R, Arpat AB, Asher G, Baldi P, de Bekker C, Bell-Pedersen D, Blau J, Brown S, Ceriani MF, Chen Z, Chiu JC, Cox J, Crowell AM, DeBruyne JP, Dijk DJ, DiTacchio L, Doyle FJ, Duffield GE, Dunlap JC, Eckel-Mahan K, Esser KA, FitzGerald GA, Forger DB, Francey LJ, Fu YH, Gachon F, Gatfield D, de Goede P, Golden SS, Green C, Harer J, Harmer S, Haspel J, Hastings MH, Herzel H, Herzog ED, Hoffmann C, Hong C, Hughey JJ, Hurley JM, de la Iglesia HO, Johnson C, Kay SA, Koike N, Kornacker K, Kramer A, Lamia K, Leise T, Lewis SA, Li J, Li X, Liu AC, Loros JJ, Martino TA, Menet JS, Merrow M, Millar AJ, Mockler T, Naef F, Nagoshi E, Nitabach MN, Olmedo M, Nusinow DA, Ptáček LJ, Rand D, Reddy AB, Robles MS, Roenneberg T, Rosbash M, Ruben MD, Rund SSC, Sancar A, Sassone-Corsi P, Sehgal A, Sherrill-Mix S, Skene DJ, Storch KF, Takahashi JS, Ueda HR, Wang H, Weitz C, Westermark PO, Wijnen H, Xu Y, Wu G, Yoo SH, Young M, Zhang EE, Zielinski T, Hogenesch JB.

J Biol Rhythms. 2017 Oct;32(5):380-393. doi: 10.1177/0748730417728663. Epub 2017 Nov 3.

11.

[Characterization of rhythmic liver physiology by nuclear proteomics].

Mauvoisin D, Gachon F.

Med Sci (Paris). 2017 Jun-Jul;33(6-7):573-576. doi: 10.1051/medsci/20173306005. Epub 2017 Jul 19. French. No abstract available.

12.

Lipidomics reveals diurnal lipid oscillations in human skeletal muscle persisting in cellular myotubes cultured in vitro.

Loizides-Mangold U, Perrin L, Vandereycken B, Betts JA, Walhin JP, Templeman I, Chanon S, Weger BD, Durand C, Robert M, Paz Montoya J, Moniatte M, Karagounis LG, Johnston JD, Gachon F, Lefai E, Riezman H, Dibner C.

Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):E8565-E8574. doi: 10.1073/pnas.1705821114. Epub 2017 Sep 25.

13.

The genomic landscape of human cellular circadian variation points to a novel role for the signalosome.

Gaspar L, Howald C, Popadin K, Maier B, Mauvoisin D, Moriggi E, Gutierrez-Arcelus M, Falconnet E, Borel C, Kunz D, Kramer A, Gachon F, Dermitzakis ET, Antonarakis SE, Brown SA.

Elife. 2017 Sep 4;6. pii: e24994. doi: 10.7554/eLife.24994.

14.

Circadian and Feeding Rhythms Orchestrate the Diurnal Liver Acetylome.

Mauvoisin D, Atger F, Dayon L, Núñez Galindo A, Wang J, Martin E, Da Silva L, Montoliu I, Collino S, Martin FP, Ratajczak J, Cantó C, Kussmann M, Naef F, Gachon F.

Cell Rep. 2017 Aug 15;20(7):1729-1743. doi: 10.1016/j.celrep.2017.07.065.

15.

Diurnal Oscillations in Liver Mass and Cell Size Accompany Ribosome Assembly Cycles.

Sinturel F, Gerber A, Mauvoisin D, Wang J, Gatfield D, Stubblefield JJ, Green CB, Gachon F, Schibler U.

Cell. 2017 May 4;169(4):651-663.e14. doi: 10.1016/j.cell.2017.04.015.

16.

Transcriptional regulatory logic of the diurnal cycle in the mouse liver.

Sobel JA, Krier I, Andersin T, Raghav S, Canella D, Gilardi F, Kalantzi AS, Rey G, Weger B, Gachon F, Dal Peraro M, Hernandez N, Schibler U, Deplancke B, Naef F; CycliX consortium.

PLoS Biol. 2017 Apr 17;15(4):e2001069. doi: 10.1371/journal.pbio.2001069. eCollection 2017 Apr.

17.

Regulation of Mammalian Physiology by Interconnected Circadian and Feeding Rhythms.

Atger F, Mauvoisin D, Weger B, Gobet C, Gachon F.

Front Endocrinol (Lausanne). 2017 Mar 8;8:42. doi: 10.3389/fendo.2017.00042. eCollection 2017. Review.

18.

Glucose Homeostasis: Regulation by Peripheral Circadian Clocks in Rodents and Humans.

Gachon F, Loizides-Mangold U, Petrenko V, Dibner C.

Endocrinology. 2017 May 1;158(5):1074-1084. doi: 10.1210/en.2017-00218. Review.

PMID:
28324069
19.

Pancreatic α- and β-cellular clocks have distinct molecular properties and impact on islet hormone secretion and gene expression.

Petrenko V, Saini C, Giovannoni L, Gobet C, Sage D, Unser M, Heddad Masson M, Gu G, Bosco D, Gachon F, Philippe J, Dibner C.

Genes Dev. 2017 Feb 15;31(4):383-398. doi: 10.1101/gad.290379.116. Epub 2017 Mar 8.

20.

Extensive Regulation of Diurnal Transcription and Metabolism by Glucocorticoids.

Weger BD, Weger M, Görling B, Schink A, Gobet C, Keime C, Poschet G, Jost B, Krone N, Hell R, Gachon F, Luy B, Dickmeis T.

PLoS Genet. 2016 Dec 12;12(12):e1006512. doi: 10.1371/journal.pgen.1006512. eCollection 2016 Dec.

21.

Nuclear Proteomics Uncovers Diurnal Regulatory Landscapes in Mouse Liver.

Wang J, Mauvoisin D, Martin E, Atger F, Galindo AN, Dayon L, Sizzano F, Palini A, Kussmann M, Waridel P, Quadroni M, Dulić V, Naef F, Gachon F.

Cell Metab. 2017 Jan 10;25(1):102-117. doi: 10.1016/j.cmet.2016.10.003. Epub 2016 Nov 3.

22.

Perturbed rhythmic activation of signaling pathways in mice deficient for Sterol Carrier Protein 2-dependent diurnal lipid transport and metabolism.

Jouffe C, Gobet C, Martin E, Métairon S, Morin-Rivron D, Masoodi M, Gachon F.

Sci Rep. 2016 Apr 21;6:24631. doi: 10.1038/srep24631.

23.

USP2-45 Is a Circadian Clock Output Effector Regulating Calcium Absorption at the Post-Translational Level.

Pouly D, Chenaux S, Martin V, Babis M, Koch R, Nagoshi E, Katanaev VL, Gachon F, Staub O.

PLoS One. 2016 Jan 12;11(1):e0145155. doi: 10.1371/journal.pone.0145155. eCollection 2016.

24.

Circadian and feeding rhythms differentially affect rhythmic mRNA transcription and translation in mouse liver.

Atger F, Gobet C, Marquis J, Martin E, Wang J, Weger B, Lefebvre G, Descombes P, Naef F, Gachon F.

Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6579-88. doi: 10.1073/pnas.1515308112. Epub 2015 Nov 9.

25.

Circadian Dysfunction and Obesity: Is Leptin the Missing Link?

Dibner C, Gachon F.

Cell Metab. 2015 Sep 1;22(3):359-60. doi: 10.1016/j.cmet.2015.08.008.

26.

Development of a freeze-dried kit formulation for the preparation of 99mTc-NTP 15-5, a radiotracer for scintigraphic imaging of proteoglycans.

Vidal A, Gaumet V, Galmier MJ, Besse S, Leal F, Gachon F, Viot G, Métin J, Chezal JM, Miot-Noirault E, Auzeloux P.

Appl Radiat Isot. 2015 Jul;101:1-9. doi: 10.1016/j.apradiso.2015.03.010. Epub 2015 Mar 11.

PMID:
25813000
27.

Proteomics and circadian rhythms: it's all about signaling!

Mauvoisin D, Dayon L, Gachon F, Kussmann M.

Proteomics. 2015 Jan;15(2-3):310-7. doi: 10.1002/pmic.201400187. Epub 2014 Sep 22. Review.

28.

Local renal circadian clocks control fluid-electrolyte homeostasis and BP.

Tokonami N, Mordasini D, Pradervand S, Centeno G, Jouffe C, Maillard M, Bonny O, Gachon F, Gomez RA, Sequeira-Lopez ML, Firsov D.

J Am Soc Nephrol. 2014 Jul;25(7):1430-9. doi: 10.1681/ASN.2013060641. Epub 2014 Mar 20.

29.

Circadian clock-dependent and -independent rhythmic proteomes implement distinct diurnal functions in mouse liver.

Mauvoisin D, Wang J, Jouffe C, Martin E, Atger F, Waridel P, Quadroni M, Gachon F, Naef F.

Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):167-72. doi: 10.1073/pnas.1314066111. Epub 2013 Dec 16.

30.

(123)I-BZA2 as a melanin-targeted radiotracer for the identification of melanoma metastases: results and perspectives of a multicenter phase III clinical trial.

Cachin F, Miot-Noirault E, Gillet B, Isnardi V, Labeille B, Payoux P, Meyer N, Cammilleri S, Gaudy C, Razzouk-Cadet M, Lacour JP, Granel-Brocard F, Tychyj C, Benbouzid F, Grange JD, Baulieu F, Kelly A, Merlin C, Mestas D, Gachon F, Chezal JM, Degoul F, D'Incan M.

J Nucl Med. 2014 Jan;55(1):15-22. doi: 10.2967/jnumed.113.123554. Epub 2013 Nov 21.

31.

Chronopharmacology: new insights and therapeutic implications.

Dallmann R, Brown SA, Gachon F.

Annu Rev Pharmacol Toxicol. 2014;54:339-61. doi: 10.1146/annurev-pharmtox-011613-135923. Epub 2013 Oct 16. Review.

32.

The circadian clock coordinates ribosome biogenesis.

Jouffe C, Cretenet G, Symul L, Martin E, Atger F, Naef F, Gachon F.

PLoS Biol. 2013;11(1):e1001455. doi: 10.1371/journal.pbio.1001455. Epub 2013 Jan 3.

33.

Proline- and acidic amino acid-rich basic leucine zipper proteins modulate peroxisome proliferator-activated receptor alpha (PPARalpha) activity.

Gachon F, Leuenberger N, Claudel T, Gos P, Jouffe C, Fleury Olela F, de Mollerat du Jeu X, Wahli W, Schibler U.

Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4794-9. doi: 10.1073/pnas.1002862108. Epub 2011 Mar 7.

34.

The role of circadian timing system on drug metabolism and detoxification.

Gachon F, Firsov D.

Expert Opin Drug Metab Toxicol. 2011 Feb;7(2):147-58. doi: 10.1517/17425255.2011.544251. Epub 2010 Dec 31. Review.

35.

Cardiac hypertrophy, low blood pressure, and low aldosterone levels in mice devoid of the three circadian PAR bZip transcription factors DBP, HLF, and TEF.

Wang Q, Maillard M, Schibler U, Burnier M, Gachon F.

Am J Physiol Regul Integr Comp Physiol. 2010 Oct;299(4):R1013-9. doi: 10.1152/ajpregu.00241.2010. Epub 2010 Aug 4.

36.

Circadian clock-coordinated hepatic lipid metabolism: only transcriptional regulation?

Gachon F, Bonnefont X.

Aging (Albany NY). 2010 Mar 20;2(2):101-6.

37.

Circadian clock-coordinated 12 Hr period rhythmic activation of the IRE1alpha pathway controls lipid metabolism in mouse liver.

Cretenet G, Le Clech M, Gachon F.

Cell Metab. 2010 Jan;11(1):47-57. doi: 10.1016/j.cmet.2009.11.002.

38.

Phase I dose escalation trial of docetaxel plus curcumin in patients with advanced and metastatic breast cancer.

Bayet-Robert M, Kwiatkowski F, Leheurteur M, Gachon F, Planchat E, Abrial C, Mouret-Reynier MA, Durando X, Barthomeuf C, Chollet P.

Cancer Biol Ther. 2010 Jan;9(1):8-14. Epub 2010 Jan 21.

PMID:
19901561
39.
40.

Crosstalk between xenobiotics metabolism and circadian clock.

Claudel T, Cretenet G, Saumet A, Gachon F.

FEBS Lett. 2007 Jul 31;581(19):3626-33. Epub 2007 Apr 17. Review.

41.

A novel role for proline- and acid-rich basic region leucine zipper (PAR bZIP) proteins in the transcriptional regulation of a BH3-only proapoptotic gene.

Benito A, Gutierrez O, Pipaon C, Real PJ, Gachon F, Ritchie AE, Fernandez-Luna JL.

J Biol Chem. 2006 Dec 15;281(50):38351-7. Epub 2006 Oct 20.

42.
43.

Circulating chromogranin a and hormone refractory prostate cancer chemotherapy.

Cabrespine A, Guy L, Gachon F, Curé H, Chollet P, Bay JO.

J Urol. 2006 Apr;175(4):1347-52.

PMID:
16515996
44.

[Stress, cancer and circadian rhythm of melatonin].

Kwiatkowski F, Abrial C, Gachon F, Chevrier R, Curé H, Chollet P.

Pathol Biol (Paris). 2005 Jun;53(5):269-72. Epub 2005 Jan 20. Review. French.

PMID:
15939136
45.

[Therapeutic potential of melatonin in cancer treatment].

Abrial C, Kwiatkowski F, Chevrier R, Gachon F, Curé H, Chollet P.

Pathol Biol (Paris). 2005 Jun;53(5):265-8. Epub 2005 Jan 20. Review. French.

PMID:
15939135
46.

Early CYFRA 21-1 variation predicts tumor response to chemotherapy and survival in locally advanced non-small cell lung cancer patients.

Merle P, Janicot H, Filaire M, Roux D, Bailly C, Vincent C, Gachon F, Tchirkov A, Kwiatkowski F, Naamé A, Escande G, Caillaud D, Verrelle P.

Int J Biol Markers. 2004 Oct-Dec;19(4):310-5.

PMID:
15646838
47.

The mammalian circadian timing system: from gene expression to physiology.

Gachon F, Nagoshi E, Brown SA, Ripperger J, Schibler U.

Chromosoma. 2004 Sep;113(3):103-12. Epub 2004 Aug 3. Review.

PMID:
15338234
48.

The loss of circadian PAR bZip transcription factors results in epilepsy.

Gachon F, Fonjallaz P, Damiola F, Gos P, Kodama T, Zakany J, Duboule D, Petit B, Tafti M, Schibler U.

Genes Dev. 2004 Jun 15;18(12):1397-412. Epub 2004 Jun 2.

49.

[Is there a circadian rhythm of interleukin 15 in humans?].

Chevalier V, Gachon F, Kwiatkowski F, Papon J, Curé H, Doly M, Madelmont JC, Chollet P.

Pathol Biol (Paris). 2003 Jun;51(4):194-6. French.

PMID:
12852986
50.

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