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Items: 48

1.

Inflamed phenotype of splenic marginal zone B-cell lymphomas with expression of PD-L1 by intratumoral monocytes/macrophages and dendritic cells.

Vincent-Fabert C, Soubeyran I, Velasco V, Parrens M, Jeannet R, Lereclus E, Gachard N, Feuillard J, Faumont N.

Cell Mol Immunol. 2019 Jun;16(6):621-624. doi: 10.1038/s41423-019-0228-y. Epub 2019 Apr 9. No abstract available.

PMID:
30967638
2.

Adult Bone Marrow Three-Dimensional Phenotypic Landscape of B-Cell Differentiation.

Carrion C, Guérin E, Gachard N, le Guyader A, Giraut S, Feuillard J.

Cytometry B Clin Cytom. 2019 Jan;96(1):30-38. doi: 10.1002/cyto.b.21747. Epub 2018 Nov 18.

PMID:
30450798
3.

Pathology of Nerve Biopsy and Diagnostic Yield of PCR-Based Clonality Testing in Neurolymphomatosis.

Duchesne M, Roussellet O, Maisonobe T, Gachard N, Rizzo D, Armand M, Viala K, Richard L, Delage-Corre M, Jaccard A, Corcia P, Vallat JM, Magy L.

J Neuropathol Exp Neurol. 2018 Sep 1;77(9):769-781. doi: 10.1093/jnen/nly055.

PMID:
30011033
4.

Normal serum protein electrophoresis and mutated IGHV genes detect very slowly evolving chronic lymphocytic leukemia patients.

Chauzeix J, Laforêt MP, Deveza M, Crowther L, Marcellaud E, Derouault P, Lia AS, Boyer F, Bargues N, Olombel G, Jaccard A, Feuillard J, Gachard N, Rizzo D.

Cancer Med. 2018 Jun;7(6):2621-2628. doi: 10.1002/cam4.1510. Epub 2018 May 9.

5.

Neurotensin receptor type 2 protects B-cell chronic lymphocytic leukemia cells from apoptosis.

Abbaci A, Talbot H, Saada S, Gachard N, Abraham J, Jaccard A, Bordessoule D, Fauchais AL, Naves T, Jauberteau MO.

Oncogene. 2018 Feb 8;37(6):756-767. doi: 10.1038/onc.2017.365. Epub 2017 Oct 23.

6.

Molecular analysis of immunoglobulin variable genes supports a germinal center experienced normal counterpart in primary cutaneous diffuse large B-cell lymphoma, leg-type.

Pham-Ledard A, Prochazkova-Carlotti M, Deveza M, Laforet MP, Beylot-Barry M, Vergier B, Parrens M, Feuillard J, Merlio JP, Gachard N.

J Dermatol Sci. 2017 Nov;88(2):238-246. doi: 10.1016/j.jdermsci.2017.07.008. Epub 2017 Jul 26.

PMID:
28838616
7.

Impact of cytogenetic abnormalities in adults with Ph-negative B-cell precursor acute lymphoblastic leukemia.

Lafage-Pochitaloff M, Baranger L, Hunault M, Cuccuini W, Lefebvre C, Bidet A, Tigaud I, Eclache V, Delabesse E, Bilhou-Nabéra C, Terré C, Chapiro E, Gachard N, Mozziconacci MJ, Ameye G, Porter S, Grardel N, Béné MC, Chalandon Y, Graux C, Huguet F, Lhéritier V, Ifrah N, Dombret H; Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL).

Blood. 2017 Oct 19;130(16):1832-1844. doi: 10.1182/blood-2017-05-783852. Epub 2017 Aug 8.

8.

c-Myc dysregulation is a co-transforming event for nuclear factor-κB activated B cells.

David A, Arnaud N, Fradet M, Lascaux H, Ouk-Martin C, Gachard N, Zimber-Strobl U, Feuillard J, Faumont N.

Haematologica. 2017 May;102(5):883-894. doi: 10.3324/haematol.2016.156281. Epub 2017 Feb 23.

9.

A novel t(3;13)(q13;q12) translocation fusing FLT3 with GOLGB1: toward myeloid/lymphoid neoplasms with eosinophilia and rearrangement of FLT3?

Troadec E, Dobbelstein S, Bertrand P, Faumont N, Trimoreau F, Touati M, Chauzeix J, Petit B, Bordessoule D, Feuillard J, Bastard C, Gachard N.

Leukemia. 2017 Feb;31(2):514-517. doi: 10.1038/leu.2016.304. Epub 2016 Oct 31. No abstract available.

10.

Recommendations for accreditation of laboratories in molecular biology of hematologic malignancies.

Flandrin-Gresta P, Cornillet P, Hayette S, Gachard N, Tondeur S, Mauté C, Cayuela JM; Groupe des biologistes moléculaires des hémopathies malignes (GBMHM).

Ann Biol Clin (Paris). 2015 Sep-Oct;73(5):595-630. doi: 10.1684/abc.2015.1067.

11.

IgM peak independently predicts treatment-free survival in chronic lymphocytic leukemia and correlates with accumulation of adverse oncogenetic events.

Rizzo D, Chauzeix J, Trimoreau F, Woillard JB, Genevieve F, Bouvier A, Labrousse J, Poli C, Guerin E, Dmytruk N, Remenieras L, Feuillard J, Gachard N.

Leukemia. 2015 Feb;29(2):337-45. doi: 10.1038/leu.2014.198. Epub 2014 Jun 19.

PMID:
24943833
12.

Clinical and biological characterization of patients with low (0.1-2%) JAK2V617F allele burden at diagnosis.

Lippert E, Mansier O, Migeon M, Denys B, Nilsson A, Rosmond C, Lodé L, Ugo V, Lascaux A, Bellosillo B, Martinez-Lopez J, Naguib D, Gachard N, Maroc N, Hermouet S.

Haematologica. 2014 Jul;99(7):e98-101. doi: 10.3324/haematol.2014.107656. Epub 2014 May 16. No abstract available.

13.

14q deletions are associated with trisomy 12, NOTCH1 mutations and unmutated IGHV genes in chronic lymphocytic leukemia and small lymphocytic lymphoma.

Cosson A, Chapiro E, Belhouachi N, Cung HA, Keren B, Damm F, Algrin C, Lefebvre C, Fert-Ferrer S, Luquet I, Gachard N, Mugneret F, Terre C, Collonge-Rame MA, Michaux L, Rafdord-Weiss I, Talmant P, Veronese L, Nadal N, Struski S, Barin C, Helias C, Lafage M, Lippert E, Auger N, Eclache V, Roos-Weil D, Leblond V, Settegrana C, Maloum K, Davi F, Merle-Beral H, Lesty C, Nguyen-Khac F; Groupe Francophone de Cytogénétique Hématologique.

Genes Chromosomes Cancer. 2014 Aug;53(8):657-66. doi: 10.1002/gcc.22176. Epub 2014 Apr 12.

PMID:
24729385
14.

RelA and RelB cross-talk and function in Epstein-Barr virus transformed B cells.

Chanut A, Duguet F, Marfak A, David A, Petit B, Parrens M, Durand-Panteix S, Boulin-Deveza M, Gachard N, Youlyouz-Marfak I, Bordessoule D, Feuillard J, Faumont N.

Leukemia. 2014 Apr;28(4):871-9. doi: 10.1038/leu.2013.274. Epub 2013 Sep 23.

PMID:
24056880
15.

Outcome of older patients with acute myeloid leukemia in first relapse.

Sarkozy C, Gardin C, Gachard N, Merabet F, Turlure P, Malfuson JV, Pautas C, Micol JB, Thomas X, Quesnel B, Celli-Lebras K, Preudhomme C, Terré C, Fenaux P, Chevret S, Castaigne S, Dombret H.

Am J Hematol. 2013 Sep;88(9):758-64. doi: 10.1002/ajh.23498. Epub 2013 Aug 7.

16.

Very low levels of surface CD45 reflect CLL cell fragility, are inversely correlated with trisomy 12 and are associated with increased treatment-free survival.

Rizzo D, Lotay A, Gachard N, Marfak I, Faucher JL, Trimoreau F, Guérin E, Bordessoule D, Jaccard A, Feuillard J.

Am J Hematol. 2013 Sep;88(9):747-53. doi: 10.1002/ajh.23494. Epub 2013 Jul 23.

17.

Neurofibromatosis-1 gene deletions and mutations in de novo adult acute myeloid leukemia.

Boudry-Labis E, Roche-Lestienne C, Nibourel O, Boissel N, Terre C, Perot C, Eclache V, Gachard N, Tigaud I, Plessis G, Cuccuini W, Geffroy S, Villenet C, Figeac M, Leprêtre F, Renneville A, Cheok M, Soulier J, Dombret H, Preudhomme C; French ALFA group.

Am J Hematol. 2013 Apr;88(4):306-11. doi: 10.1002/ajh.23403. Epub 2013 Mar 5.

18.

Design and feasibility of a novel, rapid, and simple fluorescence 26-plex rt-PCR assay for simultaneous detection of 24 fusion transcripts in adult acute myeloid leukemia.

Laforêt MP, Turlure P, Lippert E, Cornillet-Lefebvre P, Pigneux A, Pradeau R, Feuillard J, Gachard N.

J Mol Diagn. 2013 Mar;15(2):186-95. doi: 10.1016/j.jmoldx.2012.11.004. Epub 2013 Jan 11.

PMID:
23318495
19.

Superior long-term outcome with idarubicin compared with high-dose daunorubicin in patients with acute myeloid leukemia age 50 years and older.

Gardin C, Chevret S, Pautas C, Turlure P, Raffoux E, Thomas X, Quesnel B, de Revel T, de Botton S, Gachard N, Renneville A, Boissel N, Preudhomme C, Terré C, Fenaux P, Bordessoule D, Celli-Lebras K, Castaigne S, Dombret H.

J Clin Oncol. 2013 Jan 20;31(3):321-7. doi: 10.1200/JCO.2011.40.3642. Epub 2012 Dec 17.

PMID:
23248249
20.

T/B ratio does not reflect levels of ZAP70 expression in clonal CLL B-cells due to ZAP70 overexpression in patient T-cells.

Rizzo D, Bouvier G, Youlyouz-Marfak I, Guerin E, Trimoreau F, Bordessoule D, Jaccard A, Gachard N, Feuillard J.

Cytometry B Clin Cytom. 2013 Mar;84(2):125-32. doi: 10.1002/cyto.b.21055. Epub 2012 Dec 6.

21.

Chromosomal aberrations and their prognostic value in a series of 174 untreated patients with Waldenström's macroglobulinemia.

Nguyen-Khac F, Lambert J, Chapiro E, Grelier A, Mould S, Barin C, Daudignon A, Gachard N, Struski S, Henry C, Penther D, Mossafa H, Andrieux J, Eclache V, Bilhou-Nabera C, Luquet I, Terre C, Baranger L, Mugneret F, Chiesa J, Mozziconacci MJ, Callet-Bauchu E, Veronese L, Blons H, Owen R, Lejeune J, Chevret S, Merle-Beral H, Leblondon V; Groupe Français d'Etude de la Leucémie Lymphoïde Chronique et Maladie de Waldenström (GFCLL/MW); Groupe Ouest-Est d’étude des Leucémie Aiguës et Autres Maladies du Sang (GOELAMS); Groupe d’Etude des Lymphomes de l’Adulte (GELA).

Haematologica. 2013 Apr;98(4):649-54. doi: 10.3324/haematol.2012.070458. Epub 2012 Oct 12.

22.

IGHV gene features and MYD88 L265P mutation separate the three marginal zone lymphoma entities and Waldenström macroglobulinemia/lymphoplasmacytic lymphomas.

Gachard N, Parrens M, Soubeyran I, Petit B, Marfak A, Rizzo D, Devesa M, Delage-Corre M, Coste V, Laforêt MP, de Mascarel A, Merlio JP, Bouabdhalla K, Milpied N, Soubeyran P, Schmitt A, Bordessoule D, Cogné M, Feuillard J.

Leukemia. 2013 Jan;27(1):183-9. doi: 10.1038/leu.2012.257. Epub 2012 Sep 4.

PMID:
22944768
23.

PICALM-MLLT10 acute myeloid leukemia: a French cohort of 18 patients.

Borel C, Dastugue N, Cances-Lauwers V, Mozziconacci MJ, Prebet T, Vey N, Pigneux A, Lippert E, Visanica S, Legrand F, Rault JP, Taviaux S, Bastard C, Mugneret F, Collonges Rames MA, Gachard N, Talmant P, Delabesse E, Récher C.

Leuk Res. 2012 Nov;36(11):1365-9. doi: 10.1016/j.leukres.2012.07.008. Epub 2012 Aug 5.

PMID:
22871473
24.

Chronic lymphocytic leukemia and prolymphocytic leukemia with MYC translocations: a subgroup with an aggressive disease course.

Put N, Van Roosbroeck K, Konings P, Meeus P, Brusselmans C, Rack K, Gervais C, Nguyen-Khac F, Chapiro E, Radford-Weiss I, Struski S, Dastugue N, Gachard N, Lefebvre C, Barin C, Eclache V, Fert-Ferrer S, Laibe S, Mozziconacci MJ, Quilichini B, Poirel HA, Wlodarska I, Hagemeijer A, Moreau Y, Vandenberghe P, Michaux L; BCGHo and the GFCH.

Ann Hematol. 2012 Jun;91(6):863-73. doi: 10.1007/s00277-011-1393-y. Epub 2011 Dec 30.

PMID:
22205151
25.

A new Leukemia Prognostic Scoring System for refractory/relapsed adult acute myelogeneous leukaemia patients: a GOELAMS study.

Chevallier P, Labopin M, Turlure P, Prebet T, Pigneux A, Hunault M, Filanovsky K, Cornillet-Lefebvre P, Luquet I, Lode L, Richebourg S, Blanchet O, Gachard N, Vey N, Ifrah N, Milpied N, Harousseau JL, Bene MC, Mohty M, Delaunay J.

Leukemia. 2011 Jun;25(6):939-44. doi: 10.1038/leu.2011.25. Epub 2011 Feb 18.

PMID:
21331073
26.

Specific chromosomal IG translocations have different prognoses in chronic lymphocytic leukemia.

Nguyen-Khac F, Chapiro E, Lesty C, Grelier A, Luquet I, Radford-Weiss I, Lefebvre C, Fert-Ferrer S, Callet-Bauchu E, Lippert E, Raggueneau V, Michaux L, Barin C, Collonge-Rame MA, Mugneret F, Eclache V, Taviaux S, Dastugue N, Richebourg S, Struski S, Talmant P, Baranger L, Gachard N, Gervais C, Quilichini B, Settegrana C, Maloum K, Davi F, Merle-Béral H.

Am J Blood Res. 2011;1(1):13-21. Epub 2011 Apr 15.

27.

Efficacy of L-asparaginase with methotrexate and dexamethasone (AspaMetDex regimen) in patients with refractory or relapsing extranodal NK/T-cell lymphoma, a phase 2 study.

Jaccard A, Gachard N, Marin B, Rogez S, Audrain M, Suarez F, Tilly H, Morschhauser F, Thieblemont C, Ysebaert L, Devidas A, Petit B, de Leval L, Gaulard P, Feuillard J, Bordessoule D, Hermine O; GELA and GOELAMS Intergroup.

Blood. 2011 Feb 10;117(6):1834-9. doi: 10.1182/blood-2010-09-307454. Epub 2010 Dec 1.

28.

Chromosomal abnormalities in transformed Ph-negative myeloproliferative neoplasms are associated to the transformation subtype and independent of JAK2 and the TET2 mutations.

Nguyen-Khac F, Lesty C, Eclache V, Couronné L, Kosmider O, Andrieux J, Collonge-Rame MA, Penther D, Lafage M, Bilhou-Nabera C, Chapiro E, Mozziconacci MJ, Mugneret F, Gachard N, Nadal N, Lippert E, Struski S, Dastugue N, Cabrol C, Bernard OA; Groupe Francophone de Cytogénétique Hématologique.

Genes Chromosomes Cancer. 2010 Oct;49(10):919-27. doi: 10.1002/gcc.20802.

PMID:
20629097
29.

Loss of the Y chromosome in Philadelphia-positive cells predicts a poor response of chronic myeloid leukemia patients to imatinib mesylate therapy.

Lippert E, Etienne G, Mozziconacci MJ, Laibe S, Gervais C, Girault S, Gachard N, Tigaud I, Dastugue N, Huguet F, Fort MP, Legros L, Eclache V, Mahon FX.

Haematologica. 2010 Sep;95(9):1604-7. doi: 10.3324/haematol.2009.019109. Epub 2010 Apr 30.

30.

Analyses of TET2 mutations in post-myeloproliferative neoplasm acute myeloid leukemias.

Couronné L, Lippert E, Andrieux J, Kosmider O, Radford-Weiss I, Penther D, Dastugue N, Mugneret F, Lafage M, Gachard N, Nadal N, Bernard OA, Nguyen-Khac F.

Leukemia. 2010 Jan;24(1):201-3. doi: 10.1038/leu.2009.169. Epub 2009 Aug 27. No abstract available.

PMID:
19710701
31.

Among 157 marginal zone lymphomas, DBA.44(CD76) expression is restricted to tumour cells infiltrating the red pulp of the spleen with a diffuse architectural pattern.

Petit B, Parrens M, Soubeyran I, Costes-Martineau V, Gachard N, Boulin M, Laurent C, Marfak A, Labrousse F, Bordessoule D, Feuillard J.

Histopathology. 2009 Apr;54(5):626-31. doi: 10.1111/j.1365-2559.2009.03262.x. No abstract available.

PMID:
19413643
32.

The favorable impact of CEBPA mutations in patients with acute myeloid leukemia is only observed in the absence of associated cytogenetic abnormalities and FLT3 internal duplication.

Renneville A, Boissel N, Gachard N, Naguib D, Bastard C, de Botton S, Nibourel O, Pautas C, Reman O, Thomas X, Gardin C, Terré C, Castaigne S, Preudhomme C, Dombret H.

Blood. 2009 May 21;113(21):5090-3. doi: 10.1182/blood-2008-12-194704. Epub 2009 Mar 16.

33.

L-asparaginase-based treatment of 15 western patients with extranodal NK/T-cell lymphoma and leukemia and a review of the literature.

Jaccard A, Petit B, Girault S, Suarez F, Gressin R, Zini JM, Coiteux V, Larroche C, Devidas A, Thiéblemont C, Gaulard P, Marin B, Gachard N, Bordessoule D, Hermine O.

Ann Oncol. 2009 Jan;20(1):110-6. doi: 10.1093/annonc/mdn542. Epub 2008 Aug 13. Review.

PMID:
18701429
34.

Splenic marginal zone lymphomas and lymphoplasmacytic lymphomas originate from B-cell compartments with two different antigen-exposure histories.

Parrens M, Gachard N, Petit B, Marfak A, Troadec E, Bouabdhalla K, Milpied N, Merlio JP, de Mascarel A, Laurent C, Soubeyran I, Coste V, Labrousse F, Cogné M, Feuillard J.

Leukemia. 2008 Aug;22(8):1621-4. doi: 10.1038/leu.2008.24. Epub 2008 Feb 28. No abstract available.

PMID:
18305562
35.

Multicenter study of ZAP-70 expression in patients with B-cell chronic lymphocytic leukemia using an optimized flow cytometry method.

Gachard N, Salviat A, Boutet C, Arnoulet C, Durrieu F, Lenormand B, Leprêtre S, Olschwang S, Jardin F, Lafage-Pochitaloff M, Penther D, Sainty D, Reminieras L, Feuillard J, Béné MC; GEIL.

Haematologica. 2008 Feb;93(2):215-23. doi: 10.3324/haematol.11622. Epub 2008 Jan 26.

36.

Identification of a novel p53-dependent activation pathway of STAT1 by antitumour genotoxic agents.

Youlyouz-Marfak I, Gachard N, Le Clorennec C, Najjar I, Baran-Marszak F, Reminieras L, May E, Bornkamm GW, Fagard R, Feuillard J.

Cell Death Differ. 2008 Feb;15(2):376-85. Epub 2007 Nov 9.

37.

Indolent lymphoplasmacytic and marginal zone B-cell lymphomas: absence of both IRF4 and Ki67 expression identifies a better prognosis subgroup.

Petit B, Chaury MP, Le Clorennec C, Jaccard A, Gachard N, Moalic-Judge S, Labrousse F, Cogné M, Bordessoule D, Feuillard J.

Haematologica. 2005 Feb;90(2):200-6.

38.

The CD4+ CD56+ CD116- CD123+ CD45RA+ CD45RO- profile is specific of DC2 malignancies.

Trimoreau F, Donnard M, Turlure P, Gachard N, Bordessoule D, Feuillard J.

Haematologica. 2003 Mar;88(3):ELT10. No abstract available.

39.

CD4(+), CD56(+) DC2 acute leukemia is characterized by recurrent clonal chromosomal changes affecting 6 major targets: a study of 21 cases by the Groupe Français de Cytogénétique Hématologique.

Leroux D, Mugneret F, Callanan M, Radford-Weiss I, Dastugue N, Feuillard J, Le Mée F, Plessis G, Talmant P, Gachard N, Uettwiller F, Pages MP, Mozziconacci MJ, Eclache V, Sibille C, Avet-Loiseau H, Lafage-Pochitaloff M.

Blood. 2002 Jun 1;99(11):4154-9.

40.

Effect of platelet-activating factor on the growth of human erythroid and myeloid CD34+ progenitors.

Dupuis F, Gachard N, Allegraud A, Dulery C, Praloran V, Denizot Y.

Mediators Inflamm. 1998;7(2):99-103.

41.

Thymoma-associated pancytopenia: effectiveness of cyclosporine A.

Liozon E, Touati M, Allegraud A, Gachard N, Loustaud V, Vidal E, Bordessoule D.

Ann Hematol. 1998 Oct;77(4):175-8.

PMID:
9829850
42.

B cell compartments in multiple myeloma: flow cytometric analysis of their labelling indices and Bcl-2 protein expression.

Trimoreau F, Gachard N, Jaccard A, Boutros Toni F, Bordessoule D, Praloran V.

Hematol Cell Ther. 1998 Feb;40(1):11-6.

PMID:
9556184
43.

Spontaneous and inducible production of macrophage colony-stimulating factor by human bone marrow stromal cells.

Fixe P, Rougier F, Ostyn E, Gachard N, Faucher JL, Praloran V, Denizot Y.

Eur Cytokine Netw. 1997 Mar;8(1):91-5.

PMID:
9110154
44.

Leukemia inhibitory factor concentrations in the bone marrow plasma of healthy subjects and patients with hematologic malignancies.

Lorgeot V, Trimoreau F, Gachard N, Praloran V, Denizot Y.

Eur Cytokine Netw. 1997 Mar;8(1):57-9.

PMID:
9110149
45.

Cytogenetic study of 30 patients with multiple myeloma: comparison of 3 and 6 day bone marrow cultures stimulated or not with cytokines by using a miniaturized karyotypic method.

Brigaudeau C, Trimoreau F, Gachard N, Rouzier E, Jaccard A, Bordessoule D, Praloran V.

Br J Haematol. 1997 Mar;96(3):594-600.

PMID:
9054668
46.

Tumour necrosis factor-alpha (TNFalpha) stimulates the growth of human bone marrow stromal cells.

Rougier F, Cornu E, Gachard N, Praloran V, Denizot Y.

Mediators Inflamm. 1997;6(3):233-5.

47.

A "miniaturized" method for the karyotypic analysis of bone marrow or blood samples in hematological malignancies.

Brigaudeau C, Gachard N, Clay D, Fixe P, Rouzier E, Praloran V.

Hematol Cell Ther. 1996 Jul;38(3):275-7.

PMID:
8974792
48.

[Surveillance of iatrogenic complications in a department of cardiology. Thoughts about a preventive strategy].

Raimondeau J, Bouhour JB, Gachard N, Rouet F, Reyrolle L.

Ann Cardiol Angeiol (Paris). 1993 Sep;42(7):345-50. French.

PMID:
8285562

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