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Items: 1 to 50 of 105

1.

Engineered nanoparticles for systemic siRNA delivery to malignant brain tumours.

Karlsson J, Rui Y, Kozielski KL, Placone AL, Choi O, Tzeng SY, Kim J, Keyes JJ, Bogorad MI, Gabrielson K, Guerrero-Cazares H, Quiñones-Hinojosa A, Searson PC, Green JJ.

Nanoscale. 2019 Nov 14;11(42):20045-20057. doi: 10.1039/c9nr04795f. Epub 2019 Oct 15.

PMID:
31612183
2.

Fropofol Prevents Disease Progression in Mice with Hypertrophic Cardiomyopathy.

Huang Y, Lu H, Ren X, Li F, Bu W, Liu W, Daily WP, Saeki H, Gabrielson K, Abraham R, Eckenhoff R, Dong Gao W.

Cardiovasc Res. 2019 Aug 19. pii: cvz218. doi: 10.1093/cvr/cvz218. [Epub ahead of print]

PMID:
31424496
3.

Noninvasive Monitoring of Allogeneic Stem Cell Delivery with Dual-Modality Imaging-Visible Microcapsules in a Rabbit Model of Peripheral Arterial Disease.

Fu Y, Weiss CR, Kedziorek DA, Xie Y, Tully E, Shea SM, Solaiyappan M, Ehtiati T, Gabrielson K, Wacker FH, Bulte JWM, Kraitchman DL.

Stem Cells Int. 2019 Mar 14;2019:9732319. doi: 10.1155/2019/9732319. eCollection 2019.

5.

BLT-Immune Humanized Mice as a Model for Nivolumab-Induced Immune-Mediated Adverse Events: Comparison of the NOG and NOG-EXL Strains.

Weaver JL, Zadrozny LM, Gabrielson K, Semple KM, Shea KI, Howard KE.

Toxicol Sci. 2019 May 1;169(1):194-208. doi: 10.1093/toxsci/kfz045.

PMID:
30850839
6.

In Vivo Imaging With Confirmation by Histopathology for Increased Rigor and Reproducibility in Translational Research: A Review of Examples, Options, and Resources.

Gabrielson K, Maronpot R, Monette S, Mlynarczyk C, Ramot Y, Nyska A, Sysa-Shah P.

ILAR J. 2018 Dec 1;59(1):80-98. doi: 10.1093/ilar/ily010.

PMID:
30541081
7.

Regulatory Forum Opinion Piece*: Imaging Applications in Toxicologic Pathology-Recommendations for Use in Regulated Nonclinical Toxicity Studies.

Maronpot RR, Nyska A, Troth SP, Gabrielson K, Sysa-Shah P, Kalchenko V, Kuznetsov Y, Harmelin A, Schiffenbauer YS, Bonnel D, Stauber J, Ramot Y.

Toxicol Pathol. 2017 Jun;45(4):444-471. doi: 10.1177/0192623317710014.

PMID:
28641506
8.

Development of prostate specific membrane antigen targeted ultrasound microbubbles using bioorthogonal chemistry.

Zlitni A, Yin M, Janzen N, Chatterjee S, Lisok A, Gabrielson KL, Nimmagadda S, Pomper MG, Foster FS, Valliant JF.

PLoS One. 2017 May 4;12(5):e0176958. doi: 10.1371/journal.pone.0176958. eCollection 2017.

9.

RK-33 Radiosensitizes Prostate Cancer Cells by Blocking the RNA Helicase DDX3.

Xie M, Vesuna F, Tantravedi S, Bol GM, Heerma van Voss MR, Nugent K, Malek R, Gabrielson K, van Diest PJ, Tran PT, Raman V.

Cancer Res. 2016 Nov 1;76(21):6340-6350. Epub 2016 Sep 12.

10.

An Fc-Small Molecule Conjugate for Targeted Inhibition of the Adenosine 2A Receptor.

Hsiao PY, Kalin JH, Sun IH, Amin MN, Lo YC, Chiang MJ, Giddens J, Sysa-Shah P, Gabrielson K, Wang LX, Powell JD, Cole PA.

Chembiochem. 2016 Oct 17;17(20):1951-1960. doi: 10.1002/cbic.201600337. Epub 2016 Aug 26.

11.

Echocardiographic Characterization of a Murine Model of Hypertrophic Obstructive Cardiomyopathy Induced by Cardiac-specific Overexpression of Epidermal Growth Factor Receptor 2.

Sørensen LL, Bedja D, Sysa-Shah P, Liu H, Maxwell A, Yi X, Pozios I, Olsen NT, Abraham TP, Abraham R, Gabrielson K.

Comp Med. 2016;66(4):268-77.

12.

A preclinical murine model for the early detection of radiation-induced brain injury using magnetic resonance imaging and behavioral tests for learning and memory: with applications for the evaluation of possible stem cell imaging agents and therapies.

Ngen EJ, Wang L, Gandhi N, Kato Y, Armour M, Zhu W, Wong J, Gabrielson KL, Artemov D.

J Neurooncol. 2016 Jun;128(2):225-33. doi: 10.1007/s11060-016-2111-3. Epub 2016 Mar 28.

PMID:
27021492
13.

Bidirectional cross-regulation between ErbB2 and β-adrenergic signalling pathways.

Sysa-Shah P, Tocchetti CG, Gupta M, Rainer PP, Shen X, Kang BH, Belmonte F, Li J, Xu Y, Guo X, Bedja D, Gao WD, Paolocci N, Rath R, Sawyer DB, Naga Prasad SV, Gabrielson K.

Cardiovasc Res. 2016 Mar 1;109(3):358-73. doi: 10.1093/cvr/cvv274. Epub 2015 Dec 21.

14.

Imaging transplanted stem cells in real time using an MRI dual-contrast method.

Ngen EJ, Wang L, Kato Y, Krishnamachary B, Zhu W, Gandhi N, Smith B, Armour M, Wong J, Gabrielson K, Artemov D.

Sci Rep. 2015 Sep 2;5:13628. doi: 10.1038/srep13628.

15.

Electrocardiographic Characterization of Cardiac Hypertrophy in Mice that Overexpress the ErbB2 Receptor Tyrosine Kinase.

Sysa-Shah P, Sørensen LL, Abraham MR, Gabrielson KL.

Comp Med. 2015 Aug;65(4):295-307.

16.

ErbB2 overexpression upregulates antioxidant enzymes, reduces basal levels of reactive oxygen species, and protects against doxorubicin cardiotoxicity.

Belmonte F, Das S, Sysa-Shah P, Sivakumaran V, Stanley B, Guo X, Paolocci N, Aon MA, Nagane M, Kuppusamy P, Steenbergen C, Gabrielson K.

Am J Physiol Heart Circ Physiol. 2015 Oct;309(8):H1271-80. doi: 10.1152/ajpheart.00517.2014. Epub 2015 Aug 7.

17.

Targeting DDX3 with a small molecule inhibitor for lung cancer therapy.

Bol GM, Vesuna F, Xie M, Zeng J, Aziz K, Gandhi N, Levine A, Irving A, Korz D, Tantravedi S, Heerma van Voss MR, Gabrielson K, Bordt EA, Polster BM, Cope L, van der Groep P, Kondaskar A, Rudek MA, Hosmane RS, van der Wall E, van Diest PJ, Tran PT, Raman V.

EMBO Mol Med. 2015 May;7(5):648-69. doi: 10.15252/emmm.201404368.

18.

Parkin-independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain.

Kageyama Y, Hoshijima M, Seo K, Bedja D, Sysa-Shah P, Andrabi SA, Chen W, Höke A, Dawson VL, Dawson TM, Gabrielson K, Kass DA, Iijima M, Sesaki H.

EMBO J. 2014 Dec 1;33(23):2798-813. doi: 10.15252/embj.201488658. Epub 2014 Oct 27.

19.

AEG-1 promoter-mediated imaging of prostate cancer.

Bhatnagar A, Wang Y, Mease RC, Gabrielson M, Sysa P, Minn I, Green G, Simmons B, Gabrielson K, Sarkar S, Fisher PB, Pomper MG.

Cancer Res. 2014 Oct 15;74(20):5772-81. doi: 10.1158/0008-5472.CAN-14-0018. Epub 2014 Aug 21.

20.

A novel viscous dissecting gel for endoscopic submucosal dissection: a prospective survival study in a porcine model.

Saxena P, Simons BW, Gabrielson K, Haito-Chavez Y, Valeshabad AK, Kumbhari V, Singh VK, Lennon AM, Canto MI, Pasricha PJ, Kalloo A, Khashab MA.

Endoscopy. 2014 Jul;46(7):605-9. doi: 10.1055/s-0034-1365406. Epub 2014 Apr 25.

PMID:
24770967
21.

Fused X-ray and MR imaging guidance of intrapericardial delivery of microencapsulated human mesenchymal stem cells in immunocompetent swine.

Fu Y, Azene N, Ehtiati T, Flammang A, Gilson WD, Gabrielson K, Weiss CR, Bulte JW, Solaiyappan M, Johnston PV, Kraitchman DL.

Radiology. 2014 Aug;272(2):427-37. doi: 10.1148/radiol.14131424. Epub 2014 Apr 17.

22.

Geranylgeranylacetone blocks doxorubicin-induced cardiac toxicity and reduces cancer cell growth and invasion through RHO pathway inhibition.

Sysa-Shah P, Xu Y, Guo X, Pin S, Bedja D, Bartock R, Tsao A, Hsieh A, Wolin MS, Moens A, Raman V, Orita H, Gabrielson KL.

Mol Cancer Ther. 2014 Jul;13(7):1717-28. doi: 10.1158/1535-7163.MCT-13-0965. Epub 2014 Apr 15.

23.

Generation of a cre recombinase-conditional Nos1ap over-expression transgenic mouse.

Auer DR, Sysa-Shah P, Bedja D, Simmers JL, Pak E, Dutra A, Cohn R, Gabrielson KL, Chakravarti A, Kapoor A.

Biotechnol Lett. 2014 Jun;36(6):1179-85. doi: 10.1007/s10529-014-1473-x. Epub 2014 Feb 22.

24.

A Pkd1-Fbn1 genetic interaction implicates TGF-β signaling in the pathogenesis of vascular complications in autosomal dominant polycystic kidney disease.

Liu D, Wang CJ, Judge DP, Halushka MK, Ni J, Habashi JP, Moslehi J, Bedja D, Gabrielson KL, Xu H, Qian F, Huso D, Dietz HC, Germino GG, Watnick T.

J Am Soc Nephrol. 2014 Jan;25(1):81-91. doi: 10.1681/ASN.2012050486. Epub 2013 Sep 26.

25.

Fatal eosinophilic myocarditis develops in the absence of IFN-γ and IL-17A.

Barin JG, Baldeviano GC, Talor MV, Wu L, Ong S, Fairweather D, Bedja D, Stickel NR, Fontes JA, Cardamone AB, Zheng D, Gabrielson KL, Rose NR, Ciháková D.

J Immunol. 2013 Oct 15;191(8):4038-47. doi: 10.4049/jimmunol.1301282. Epub 2013 Sep 18.

26.

Loss of NAC1 expression is associated with defective bony patterning in the murine vertebral axis.

Yap KL, Sysa-Shah P, Bolon B, Wu RC, Gao M, Herlinger AL, Wang F, Faiola F, Huso D, Gabrielson K, Wang TL, Wang J, Shih IeM.

PLoS One. 2013 Jul 26;8(7):e69099. doi: 10.1371/journal.pone.0069099. Print 2013.

27.

Endocardial endothelium is a key determinant of force-frequency relationship in rat ventricular myocardium.

Shen X, Tan Z, Zhong X, Tian Y, Wang X, Yu B, Ramirez-Correa G, Murphy A, Gabrielson K, Paolocci N, Gao WD.

J Appl Physiol (1985). 2013 Aug 1;115(3):383-93. doi: 10.1152/japplphysiol.01415.2012. Epub 2013 May 23.

28.

Anti-hypertrophic and anti-oxidant effect of beta3-adrenergic stimulation in myocytes requires differential neuronal NOS phosphorylation.

Watts VL, Sepulveda FM, Cingolani OH, Ho AS, Niu X, Kim R, Miller KL, Vandegaer K, Bedja D, Gabrielson KL, Rameau G, O'Rourke B, Kass DA, Barouch LA.

J Mol Cell Cardiol. 2013 Sep;62:8-17. doi: 10.1016/j.yjmcc.2013.04.025. Epub 2013 May 2.

29.

Monoamine oxidase B prompts mitochondrial and cardiac dysfunction in pressure overloaded hearts.

Kaludercic N, Carpi A, Nagayama T, Sivakumaran V, Zhu G, Lai EW, Bedja D, De Mario A, Chen K, Gabrielson KL, Lindsey ML, Pacak K, Takimoto E, Shih JC, Kass DA, Di Lisa F, Paolocci N.

Antioxid Redox Signal. 2014 Jan 10;20(2):267-80. doi: 10.1089/ars.2012.4616. Epub 2013 May 22.

30.

Beneficial cardiac effects of caloric restriction are lost with age in a murine model of obesity.

AlGhatrif M, Watts VL, Niu X, Halushka M, Miller KL, Vandegaer K, Bedja D, Fox-Talbot K, Bielawska A, Gabrielson KL, Barouch LA.

J Cardiovasc Transl Res. 2013 Jun;6(3):436-45. doi: 10.1007/s12265-013-9453-4. Epub 2013 Mar 2.

PMID:
23456569
31.

TLR3 deficiency induces chronic inflammatory cardiomyopathy in resistant mice following coxsackievirus B3 infection: role for IL-4.

Abston ED, Coronado MJ, Bucek A, Onyimba JA, Brandt JE, Frisancho JA, Kim E, Bedja D, Sung YK, Radtke AJ, Gabrielson KL, Mitzner W, Fairweather D.

Am J Physiol Regul Integr Comp Physiol. 2013 Feb 15;304(4):R267-77. doi: 10.1152/ajpregu.00516.2011. Epub 2012 Dec 19.

32.

Interleukin 10 knockout frail mice develop cardiac and vascular dysfunction with increased age.

Sikka G, Miller KL, Steppan J, Pandey D, Jung SM, Fraser CD 3rd, Ellis C, Ross D, Vandegaer K, Bedja D, Gabrielson K, Walston JD, Berkowitz DE, Barouch LA.

Exp Gerontol. 2013 Feb;48(2):128-35. doi: 10.1016/j.exger.2012.11.001. Epub 2012 Nov 13.

33.

Cardiac-specific over-expression of epidermal growth factor receptor 2 (ErbB2) induces pro-survival pathways and hypertrophic cardiomyopathy in mice.

Sysa-Shah P, Xu Y, Guo X, Belmonte F, Kang B, Bedja D, Pin S, Tsuchiya N, Gabrielson K.

PLoS One. 2012;7(8):e42805. doi: 10.1371/journal.pone.0042805. Epub 2012 Aug 9.

34.

A composite polymer nanoparticle overcomes multidrug resistance and ameliorates doxorubicin-associated cardiomyopathy.

Pramanik D, Campbell NR, Das S, Gupta S, Chenna V, Bisht S, Sysa-Shah P, Bedja D, Karikari C, Steenbergen C, Gabrielson KL, Maitra A, Maitra A.

Oncotarget. 2012 Jun;3(6):640-50.

35.

Cardioprotective effect of beta-3 adrenergic receptor agonism: role of neuronal nitric oxide synthase.

Niu X, Watts VL, Cingolani OH, Sivakumaran V, Leyton-Mange JS, Ellis CL, Miller KL, Vandegaer K, Bedja D, Gabrielson KL, Paolocci N, Kass DA, Barouch LA.

J Am Coll Cardiol. 2012 May 29;59(22):1979-87. doi: 10.1016/j.jacc.2011.12.046. Erratum in: J Am Coll Cardiol. 2012 Jul 31;60(5):481.

36.

Doxorubicin-induced cardiomyopathy: from molecular mechanisms to therapeutic strategies.

Octavia Y, Tocchetti CG, Gabrielson KL, Janssens S, Crijns HJ, Moens AL.

J Mol Cell Cardiol. 2012 Jun;52(6):1213-25. doi: 10.1016/j.yjmcc.2012.03.006. Epub 2012 Mar 21. Review.

37.

IL-33 independently induces eosinophilic pericarditis and cardiac dilation: ST2 improves cardiac function.

Abston ED, Barin JG, Cihakova D, Bucek A, Coronado MJ, Brandt JE, Bedja D, Kim JB, Georgakopoulos D, Gabrielson KL, Mitzner W, Fairweather D.

Circ Heart Fail. 2012 May 1;5(3):366-75. doi: 10.1161/CIRCHEARTFAILURE.111.963769. Epub 2012 Mar 27.

38.

X-ray-visible microcapsules containing mesenchymal stem cells improve hind limb perfusion in a rabbit model of peripheral arterial disease.

Kedziorek DA, Hofmann LV, Fu Y, Gilson WD, Cosby KM, Kohl B, Barnett BP, Simons BW, Walczak P, Bulte JW, Gabrielson K, Kraitchman DL.

Stem Cells. 2012 Jun;30(6):1286-96. doi: 10.1002/stem.1096.

39.

Endothelial expression of hypoxia-inducible factor 1 protects the murine heart and aorta from pressure overload by suppression of TGF-β signaling.

Wei H, Bedja D, Koitabashi N, Xing D, Chen J, Fox-Talbot K, Rouf R, Chen S, Steenbergen C, Harmon JW, Dietz HC, Gabrielson KL, Kass DA, Semenza GL.

Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):E841-50. doi: 10.1073/pnas.1202081109. Epub 2012 Mar 8.

40.

Testosterone and interleukin-1β increase cardiac remodeling during coxsackievirus B3 myocarditis via serpin A 3n.

Coronado MJ, Brandt JE, Kim E, Bucek A, Bedja D, Abston ED, Shin J, Gabrielson KL, Mitzner W, Fairweather D.

Am J Physiol Heart Circ Physiol. 2012 Apr 15;302(8):H1726-36. doi: 10.1152/ajpheart.00783.2011. Epub 2012 Feb 10.

41.

Dose-dependent depth of tissue injury with carbon dioxide cryotherapy in porcine GI tract.

Shin EJ, Amateau SK, Kim Y, Gabrielson KL, Montgomery EA, Khashab MA, Chandrasekhara V, Rolshud D, Giday SA, Canto MI.

Gastrointest Endosc. 2012 May;75(5):1062-7. doi: 10.1016/j.gie.2011.12.007. Epub 2012 Jan 31.

PMID:
22301345
42.

Acute renal venous obstruction is more detrimental to the kidney than arterial occlusion: implication for murine models of acute kidney injury.

Li X, Liu M, Bedja D, Thoburn C, Gabrielson K, Racusen L, Rabb H.

Am J Physiol Renal Physiol. 2012 Mar 1;302(5):F519-25. doi: 10.1152/ajprenal.00011.2011. Epub 2011 Nov 23.

43.

Th2 regulation of viral myocarditis in mice: different roles for TLR3 versus TRIF in progression to chronic disease.

Abston ED, Coronado MJ, Bucek A, Bedja D, Shin J, Kim JB, Kim E, Gabrielson KL, Georgakopoulos D, Mitzner W, Fairweather D.

Clin Dev Immunol. 2012;2012:129486. doi: 10.1155/2012/129486. Epub 2011 Oct 15.

44.

Apolipoprotein A-I mimetic peptide L-4F prevents myocardial and coronary dysfunction in diabetic mice.

Vecoli C, Cao J, Neglia D, Inoue K, Sodhi K, Vanella L, Gabrielson KK, Bedja D, Paolocci N, L'abbate A, Abraham NG.

J Cell Biochem. 2011 Sep;112(9):2616-26. doi: 10.1002/jcb.23188.

45.

The innate immune response to coxsackievirus B3 predicts progression to cardiovascular disease and heart failure in male mice.

Onyimba JA, Coronado MJ, Garton AE, Kim JB, Bucek A, Bedja D, Gabrielson KL, Guilarte TR, Fairweather D.

Biol Sex Differ. 2011 Feb 21;2:2. doi: 10.1186/2042-6410-2-2.

46.

Tumor-specific imaging through progression elevated gene-3 promoter-driven gene expression.

Bhang HE, Gabrielson KL, Laterra J, Fisher PB, Pomper MG.

Nat Med. 2011 Jan;17(1):123-9. doi: 10.1038/nm.2269. Epub 2010 Dec 12.

47.

Continuing education course #1: non-invasive imaging as a problem-solving tool and translational biomarker strategy in toxicologic pathology.

Peterson RA, Gabrielson KL, Allan Johnson G, Pomper MG, Coatney RW, Winkelmann CT.

Toxicol Pathol. 2011 Jan;39(1):267-72. doi: 10.1177/0192623310390392. Epub 2010 Dec 8.

48.

Myocardial remodeling is controlled by myocyte-targeted gene regulation of phosphodiesterase type 5.

Zhang M, Takimoto E, Hsu S, Lee DI, Nagayama T, Danner T, Koitabashi N, Barth AS, Bedja D, Gabrielson KL, Wang Y, Kass DA.

J Am Coll Cardiol. 2010 Dec 7;56(24):2021-30. doi: 10.1016/j.jacc.2010.08.612. Epub 2010 Oct 21.

49.

Gastric wall healing after NOTES procedures: closure with endoscopic clips provides superior histological outcome compared with threaded tags closure.

Dray X, Krishnamurty DM, Donatelli G, Gabrielson KL, Wroblewski RJ, Shin EJ, Giday SA, Buscaglia JM, Pipitone LJ, Marohn MR, Kalloo AN, Kantsevoy SV.

Gastrointest Endosc. 2010 Aug;72(2):343-50. doi: 10.1016/j.gie.2010.02.023.

PMID:
20674622
50.

Variation in echocardiographic and cardiac hemodynamic effects of PM and ozone inhalation exposure in strains related to Nppa and Npr1 gene knock-out mice.

Tankersley CG, Peng RD, Bedga D, Gabrielson K, Champion HC.

Inhal Toxicol. 2010 Jul;22(8):695-707. doi: 10.3109/08958378.2010.487549.

PMID:
20540624

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